{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T23:46:28Z","timestamp":1782344788809,"version":"3.54.5"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008386","name":"Marmara University","doi-asserted-by":"publisher","award":["TTU-2025- 11596"],"award-info":[{"award-number":["TTU-2025- 11596"]}],"id":[{"id":"10.13039\/501100008386","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.sleep.2026.108949","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T07:42:32Z","timestamp":1775634152000},"page":"108949","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Association of morning plasma melatonin levels with chronotype, sleep disturbance, anxiety, and depression symptoms in adolescents with ADHD"],"prefix":"10.1016","volume":"144","author":[{"given":"Gizem","family":"Kuru","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-9770","authenticated-orcid":false,"given":"Hatice","family":"\u00dcnver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhan","family":"\u00dcner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goncag\u00fcl","family":"Haklar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.sleep.2026.108949_bib1","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1097\/chi.0b013e318054e724","article-title":"Practice parameter for the assessment and treatment of children and adolescents with attention-deficit\/hyperactivity disorder","volume":"46","author":"Pliszka","year":"2007","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.sleep.2026.108949_bib2","series-title":"Diagnostic and statistical manual of mental disorders (DSM-5)","year":"2013"},{"key":"10.1016\/j.sleep.2026.108949_bib3","series-title":"Lewis's child and adolescent psychiatry a comprehensive text book","first-page":"1010","article-title":"Attention-Deficit\/Hyperactivity disorder","author":"Lacramioara","year":"2017"},{"issue":"9","key":"10.1016\/j.sleep.2026.108949_bib4","first-page":"894","article-title":"Sleep in children with attention-deficit\/hyperactivity disorder: meta-analysis of subjective and objective studies","volume":"48","author":"Cortese","year":"2009","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"10","key":"10.1016\/j.sleep.2026.108949_bib5","doi-asserted-by":"crossref","first-page":"811","DOI":"10.2165\/11538990-000000000-00000","article-title":"Sleep problems in the child with attention-deficit hyperactivity disorder","volume":"24","author":"Weiss","year":"2010","journal-title":"CNS Drugs"},{"issue":"9\u201310","key":"10.1016\/j.sleep.2026.108949_bib6","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.addr.2010.05.009","article-title":"Circadian rhythms in gene expression: relationship to physiology, disease, drug disposition and drug action","volume":"62","author":"Sukumaran","year":"2010","journal-title":"Adv Drug Deliv Rev"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib7","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1177\/0748730402239679","article-title":"Life between clocks: daily temporal patterns of human chronotypes","volume":"18","author":"Roenneberg","year":"2003","journal-title":"J Biol Rhythm"},{"key":"10.1016\/j.sleep.2026.108949_bib8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.sleep.2018.03.025","article-title":"Eveningness chronotype, insomnia symptoms, and emotional and behavioural problems in adolescents","volume":"47","author":"Li","year":"2018","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2026.108949_bib9","doi-asserted-by":"crossref","first-page":"491","DOI":"10.3109\/07420528.2012.668995","article-title":"Associations between chronotypes, psychopathology, and personality among incoming college students","volume":"29","author":"Hsu","year":"2012","journal-title":"Chronobiol Int"},{"issue":"9","key":"10.1016\/j.sleep.2026.108949_bib10","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.jaac.2020.12.035","article-title":"Review: identification and management of circadian rhythm sleep disorders as a transdiagnostic feature in child and adolescent psychiatry","volume":"60","author":"Arns","year":"2021","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"3","key":"10.1016\/j.sleep.2026.108949_bib11","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s12402-016-0214-5","article-title":"A systematic review of circadian function, chronotype and chronotherapy in attention deficit hyperactivity disorder","volume":"9","author":"Coogan","year":"2017","journal-title":"Attention Deficit and Hyperactivity Disorders"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib12","first-page":"5","article-title":"The role of the circadian system in the etiology and pathophysiology of ADHD: time to redefine ADHD? Attention deficit and hyperactivity disorders","volume":"11","author":"Bijlenga","year":"2019"},{"issue":"3","key":"10.1016\/j.sleep.2026.108949_bib13","first-page":"149","article-title":"Chronotype as modulator of morning serum melatonin levels","volume":"41","author":"Morera-Fumero","year":"2013","journal-title":"Actas Esp Psiquiatr"},{"issue":"7","key":"10.1016\/j.sleep.2026.108949_bib14","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3109\/07420528.2011.596983","article-title":"Salivary melatonin rhythm as a marker of the circadian system in healthy children and those with attention-deficit\/hyperactivity disorder","volume":"28","author":"Nov\u00e1kov\u00e1","year":"2011","journal-title":"Chronobiol Int"},{"issue":"3","key":"10.1016\/j.sleep.2026.108949_bib15","first-page":"179","article-title":"Melatonin in mood disorders and anxiety","volume":"8","author":"Srinivasan","year":"2010","journal-title":"Sleep Biol Rhythm"},{"key":"10.1016\/j.sleep.2026.108949_bib16","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0091-3057(81)90048-4","article-title":"The effects of melatonin on open field behavior","volume":"15","author":"Golus","year":"1981","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.sleep.2026.108949_bib17","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0014-2999(93)90273-K","article-title":"Melatonin as an anxiolytic in rats: time dependence and interaction with the central GABAergic system","volume":"237","author":"Golombek","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.sleep.2026.108949_bib18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jpain.2008.08.007","article-title":"Preoperative anxiolytic effect of melatonin and clonidine on postoperative pain and morphine consumption in patients","volume":"10","author":"Caumo","year":"2009","journal-title":"J Pain"},{"key":"10.1016\/j.sleep.2026.108949_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/abr.abr_106_19","article-title":"The effect of melatonin on anxiety and pain of tourniquet in intravenous regional anesthesia","volume":"8","author":"Abbasivash","year":"2019","journal-title":"Adv Biomed Res"},{"issue":"24","key":"10.1016\/j.sleep.2026.108949_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232416187","article-title":"Melatonin as a potential approach to anxiety treatment","volume":"23","author":"Repova","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.sleep.2026.108949_bib21","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/0024-3205(96)00350-5","article-title":"Melatonin increases the in situ activity of tyrosine hydroxylase in the mediobasal hypothalamus of Male Syrian hamsters","volume":"59","author":"Alexiuk","year":"1996","journal-title":"Life Sci"},{"key":"10.1016\/j.sleep.2026.108949_bib22","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/0166-2236(94)90005-1","article-title":"Modulatory functions of neurotransmitters in the striatum: ach\/dopamine\/nmda interactions","volume":"17","author":"Di Chiara","year":"1994","journal-title":"Trends Neurosci"},{"issue":"7","key":"10.1016\/j.sleep.2026.108949_bib23","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/00004583-199707000-00021","article-title":"Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL)","volume":"36","author":"Kaufman","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.sleep.2026.108949_bib24","article-title":"Reliability and validity of the K-SADS-PL-DSM-5-T","author":"Unal","year":"2019","journal-title":"Turkish Journal of Psychiatry"},{"issue":"2","key":"10.1016\/j.sleep.2026.108949_bib25","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF00919127","article-title":"Normative data on revised conners parents and teacher rating scales","volume":"6","author":"Goyette","year":"1978","journal-title":"J Abnorm Child Psychol"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib26","first-page":"48","article-title":"Conners k\u0131sa form \u00f6\u011fretmen ve ana baba derecelendirme \u00f6l\u00e7eklerinin ge\u00e7erli\u011fi","volume":"18","author":"Dereboy","year":"2007","journal-title":"T\u00fcrk Psikiyatri Derg"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib27","first-page":"51","article-title":"Categorical and dimensional definitions and evaluations of symptoms of ADHD: history of the SNAP and the SWAN rating scales","volume":"10","author":"Swanson","year":"2012","journal-title":"Int J Educ Psychol Assess"},{"issue":"3","key":"10.1016\/j.sleep.2026.108949_bib28","first-page":"132","article-title":"Efforts to develop a test battery for attention deficit hyperactivity disorder and disruptive behavior disorders","volume":"8","author":"Ercan","year":"2001","journal-title":"Turkish J Child Adolescent Mental Health"},{"issue":"5","key":"10.1016\/j.sleep.2026.108949_bib29","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1080\/07420520903044505","article-title":"Assessment of chronotype in Four- to eleven-year-old children: CCTQ","volume":"26","author":"Werner","year":"2009","journal-title":"Chronobiol Int"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib30","doi-asserted-by":"crossref","first-page":"56","DOI":"10.5152\/eajm.2014.0061","article-title":"Turkish validation and adaptation of children's chronotype questionnaire (CCTQ)","volume":"47","author":"Dursun","year":"2015","journal-title":"Eurasian J Med"},{"issue":"4","key":"10.1016\/j.sleep.2026.108949_bib31","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1365-2869.1996.00251.x","article-title":"The sleep disturbance scale for children (SDSC)","volume":"5","author":"Bruni","year":"1996","journal-title":"J Sleep Res"},{"issue":"2","key":"10.1016\/j.sleep.2026.108949_bib32","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4274\/jtsm.galenos.2020.98598","article-title":"Turkish validity and reliability of the sleep disturbance scale for children","volume":"7","author":"A\u011faday\u0131","year":"2020","journal-title":"J Turkish Sleep Med"},{"issue":"3\u20134","key":"10.1016\/j.sleep.2026.108949_bib33","first-page":"103","article-title":"Children's self-report of anxiety symptoms: a comparison with their parents' ratings","volume":"33","author":"Muris","year":"2002","journal-title":"J Behav Ther Exp Psychiatr"},{"issue":"4","key":"10.1016\/j.sleep.2026.108949_bib34","first-page":"285","article-title":"Validity and reliability study of the Turkish version of the revised child anxiety and depression scale","volume":"12","author":"Polat","year":"2011","journal-title":"Anatol J Psychiatry"},{"key":"10.1016\/j.sleep.2026.108949_bib35","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.12998\/wjcc.v7.i17.2420","article-title":"Attention deficit hyperactivity disorder and comorbidity: a review of literature","volume":"7","author":"Gnanavel","year":"2019","journal-title":"World J Clin Cases"},{"issue":"3","key":"10.1016\/j.sleep.2026.108949_bib36","doi-asserted-by":"crossref","first-page":"300","DOI":"10.3390\/jpm14030300","article-title":"The high rates of comorbidity among neurodevelopmental disorders","volume":"14","author":"Bonti","year":"2024","journal-title":"J Personalized Med"},{"issue":"7","key":"10.1016\/j.sleep.2026.108949_bib37","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1002\/hup.964","article-title":"Circadian rhythm disturbances in depression","volume":"23","author":"Germain","year":"2008","journal-title":"Hum Psychopharmacol Clin Exp"},{"issue":"9791","key":"10.1016\/j.sleep.2026.108949_bib38","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S0140-6736(11)60095-0","article-title":"Novel melatonin-based therapies: potential advances in the treatment of major depression","volume":"378","author":"Hickie","year":"2011","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.sleep.2026.108949_bib39","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0063773","article-title":"Melatonin for the treatment of primary sleep disorders: a meta-analysis","volume":"8","author":"Ferracioli-Oda","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib40","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00415-020-10381-w","article-title":"Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis","volume":"269","author":"Fatemeh","year":"2022","journal-title":"J Neurol"},{"issue":"5","key":"10.1016\/j.sleep.2026.108949_bib41","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1177\/1087054719829816","article-title":"Elevated melatonin levels in children with attention deficit hyperactivity disorder: relationship to oxidative and nitrosative stress","volume":"25","author":"Avcil","year":"2021","journal-title":"J Atten Disord"},{"key":"10.1016\/j.sleep.2026.108949_bib42","series-title":"Neurological research","article-title":"Sleep disturbance in children with attention-deficit hyperactivity disorder: relationship with melatonin and behavior","author":"Souza","year":"2024"},{"key":"10.1016\/j.sleep.2026.108949_bib43","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2741\/4125","article-title":"Experimental models of melatonin-deficient hypertension","volume":"18","author":"Simko","year":"2013","journal-title":"Front Biosci"},{"key":"10.1016\/j.sleep.2026.108949_bib44","first-page":"373","article-title":"The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives","volume":"13","author":"Reiter","year":"2013","journal-title":"Mini Rev Med Chem"},{"issue":"4","key":"10.1016\/j.sleep.2026.108949_bib45","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.arcped.2022.02.005","article-title":"Sleep, chronotype, and behavior in adolescents with ADHD","volume":"29","author":"Martinez-Cayuelas","year":"2022","journal-title":"Arch Pediatr"},{"key":"10.1016\/j.sleep.2026.108949_bib46","first-page":"1","article-title":"Exploring chronotype, sleep disturbances, and temperament in adolescents with attention deficit hyperactivity disorder","author":"Cihanyurdu Erdem","year":"2025","journal-title":"Chronobiol Int"},{"issue":"6","key":"10.1016\/j.sleep.2026.108949_bib47","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/1469-7610.00667","article-title":"Sleep and alertness in children with ADHD","volume":"41","author":"Lecendreux","year":"2000","journal-title":"JCPP (J Child Psychol Psychiatry)"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib48","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/da.22422","article-title":"Chronotype associations with depression and anxiety disorders in a large cohort study","volume":"33","author":"Antypa","year":"2016","journal-title":"Depress Anxiety"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib49","doi-asserted-by":"crossref","DOI":"10.1002\/jcv2.12245","article-title":"Chronotype and depression in adolescence: results from a UK birth cohort study","volume":"5","author":"Tsomokos","year":"2024","journal-title":"JCPP Advances"},{"key":"10.1016\/j.sleep.2026.108949_bib50","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41539-023-00171-0","article-title":"A better alignment between chronotype and school timing is associated with lower grade retention in adolescents","volume":"8","author":"Rodr\u00edguez","year":"2023","journal-title":"Npj Sci Learn"},{"issue":"1","key":"10.1016\/j.sleep.2026.108949_bib51","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/07420528.2017.1387792","article-title":"Evening chronotype and sleepiness predict impairment in executive abilities and academic performance of adolescents","volume":"35","author":"Cohen-Zion","year":"2018","journal-title":"Chronobiol Int"},{"issue":"11","key":"10.1016\/j.sleep.2026.108949_bib52","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.5664\/jcsm.10126","article-title":"Longitudinal associations between high school sleep characteristics and young adult health outcomes","volume":"18","author":"Maultsby","year":"2022","journal-title":"J Clin Sleep Med"},{"issue":"2","key":"10.1016\/j.sleep.2026.108949_bib53","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/07420528.2016.1267739","article-title":"Eveningness as a risk for behavioral problems in late adolescence","volume":"34","author":"Merikanto","year":"2017","journal-title":"Chronobiol Int"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945726001887?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945726001887?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T22:49:29Z","timestamp":1782341369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945726001887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":53,"alternative-id":["S1389945726001887"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2026.108949","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of morning plasma melatonin levels with chronotype, sleep disturbance, anxiety, and depression symptoms in adolescents with ADHD","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2026.108949","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108949"}}