{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T02:31:27Z","timestamp":1786415487269,"version":"build-2736575974"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:00:00Z","timestamp":1784332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.sleep.2026.109148","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:07:10Z","timestamp":1784304430000},"page":"109148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Long-term effects of introducing novel hypnotics to users of benzodiazepine receptor agonist hypnotics"],"prefix":"10.1016","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1130-052X","authenticated-orcid":false,"given":"Nobutaka","family":"Ayani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Kurokawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chizuru","family":"Nohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Makino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nozomu","family":"Oya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riki","family":"Kitaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Narumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2026.109148_bib1","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1093\/sleep\/32.8.1027","article-title":"Incidence and risk factors of insomnia in a population-based sample","volume":"32","author":"LeBlanc","year":"2009","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2026.109148_bib2","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.70089","article-title":"The prevalence of insomnia disorder in the general population: a meta-analysis","volume":"34","author":"van Straten","year":"2025","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2026.109148_bib3","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.18782","article-title":"Incidence, persistence, and remission rates of insomnia over 5 years","volume":"3","author":"Morin","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.sleep.2026.109148_bib4","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1093\/sleep\/33.12.1633","article-title":"Sleep symptoms predict the development of the metabolic syndrome","volume":"33","author":"Troxel","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2026.109148_bib5","doi-asserted-by":"crossref","first-page":"414","DOI":"10.2337\/dc09-1124","article-title":"Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis","volume":"33","author":"Cappuccio","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.sleep.2026.109148_bib6","doi-asserted-by":"crossref","first-page":"489","DOI":"10.5664\/jcsm.26913","article-title":"Do insomnia complaints cause hypertension or cardiovascular disease?","volume":"3","author":"Phillips","year":"2007","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2026.109148_bib7","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.smrv.2018.10.006","article-title":"Insomnia as a predictor of mental disorders: a systematic review and meta-analysis","volume":"43","author":"Hertenstein","year":"2019","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2026.109148_bib8","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jad.2011.01.011","article-title":"Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies","volume":"135","author":"Baglioni","year":"2011","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2026.109148_bib9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.sleep.2011.03.020","article-title":"Chronic insomnia, quality-of-life, and utility scores: Comparison with good sleepers in a cross-sectional international survey","volume":"13","author":"L\u00e9ger","year":"2012","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2026.109148_bib10","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1177\/2047487312460020","article-title":"Insomnia and risk of cardiovascular disease: a meta-analysis","volume":"21","author":"Sofi","year":"2014","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.sleep.2026.109148_bib11","doi-asserted-by":"crossref","first-page":"487","DOI":"10.5664\/jcsm.27286","article-title":"Clinical guideline for the evaluation and management of chronic insomnia in adults","volume":"4","author":"Schutte-Rodin","year":"2008","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2026.109148_bib12","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1177\/0269881110379307","article-title":"British association for psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders","volume":"24","author":"Wilson","year":"2010","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.sleep.2026.109148_bib13","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.14035","article-title":"The european insomnia guideline: an update on the diagnosis and treatment of insomnia 2023","volume":"32","author":"Riemann","year":"2023","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2026.109148_bib14","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1001\/jamapsychiatry.2020.1767","article-title":"Effectiveness of sequential psychological and medication therapies for insomnia disorder: a randomized clinical trial","volume":"77","author":"Morin","year":"2020","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.sleep.2026.109148_bib15","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5664\/jcsm.6470","article-title":"Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American academy of sleep medicine clinical practice guideline","volume":"13","author":"Sateia","year":"2017","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2026.109148_bib16","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1177\/0269881119855343","article-title":"British association for psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update","volume":"33","author":"Wilson","year":"2019","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.sleep.2026.109148_bib17","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1056\/NEJMra1611832","article-title":"Treatment of benzodiazepine dependence","volume":"376","author":"Soyka","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.sleep.2026.109148_bib18","article-title":"Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users","volume":"3","author":"Baandrup","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.sleep.2026.109148_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.comppsych.2020.152216","article-title":"Association between discontinuation of benzodiazepine receptor agonists and post-operative delirium among inpatients with liaison intervention: a retrospective cohort study","volume":"104","author":"Omichi","year":"2021","journal-title":"Compr Psychiatry"},{"key":"10.1016\/j.sleep.2026.109148_bib20","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1136\/bmj.38623.768588.47","article-title":"Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits","volume":"331","author":"Glass","year":"2005","journal-title":"BMJ"},{"issue":"17","key":"10.1016\/j.sleep.2026.109148_bib21","doi-asserted-by":"crossref","first-page":"5138","DOI":"10.3390\/jcm11175138","article-title":"Use of melatonin and\/on ramelteon for the treatment of insomnia in older adults: a systematic review and meta-analysis","volume":"11","author":"Marupuru","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.sleep.2026.109148_bib22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41398-025-03439-8","article-title":"Comparative efficacy and safety of daridorexant, lemborexant, and suvorexant for insomnia: a systematic review and network meta-analysis","volume":"15","author":"Kishi","year":"2025","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.sleep.2026.109148_bib23","doi-asserted-by":"crossref","first-page":"184","DOI":"10.9758\/cpn.2018.16.2.184","article-title":"Assessment of switching to suvorexant versus the use of Add-on suvorexant in combination with benzodiazepine receptor agonists in insomnia patients: a retrospective study","volume":"16","author":"Hatano","year":"2018","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"10.1016\/j.sleep.2026.109148_bib24","doi-asserted-by":"crossref","first-page":"603","DOI":"10.5664\/jcsm.10946","article-title":"A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in patients switching from long-term benzodiazepine receptor agonists","volume":"20","author":"Tachibana","year":"2024","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2026.109148_bib25","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1080\/14656566.2024.2392018","article-title":"Evaluation of prescribing patterns of switching to and add-on lemborexant in patients treated with hypnotic medication: a nationwide claims database study in Japan","volume":"25","author":"Tanaka-Mizuno","year":"2024","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.sleep.2026.109148_bib26","volume":"vol. 3","year":"2004"},{"key":"10.1016\/j.sleep.2026.109148_bib27","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/aje\/kwq433","article-title":"Updating and validating the charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries","volume":"173","author":"Quan","year":"2011","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.sleep.2026.109148_bib28","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World medical association declaration of helsinki: ethical principles for medical research involving human subjects","volume":"310","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.sleep.2026.109148_bib29","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.3399\/bjgp12X625157","article-title":"Prevalence of causes of insomnia in primary care: a cross-sectional study","volume":"62","author":"Arroll","year":"2012","journal-title":"Br J Gen Pract"},{"key":"10.1016\/j.sleep.2026.109148_bib30","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1186\/s12888-023-04683-2","article-title":"Hypnotic prescription trends and patterns for the treatment of insomnia in Japan: analysis of a nationwide Japanese claims database","volume":"23","author":"Okuda","year":"2023","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.sleep.2026.109148_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0284389","article-title":"Global trends in antidepressant, atypical antipsychotic, and benzodiazepine use: a cross-sectional analysis of 64 countries","volume":"18","author":"Alabaku","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.sleep.2026.109148_bib32","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3390\/jcm7020017","article-title":"Benzodiazepines I: upping the care on downers: the evidence of risks, benefits and alternatives","volume":"7","author":"Guina","year":"2018","journal-title":"J Clin Med"},{"key":"10.1016\/j.sleep.2026.109148_bib33","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0140-6736(22)00878-9","article-title":"Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis","volume":"400","author":"De Crescenzo","year":"2022","journal-title":"Lancet"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945726003874?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945726003874?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T02:12:22Z","timestamp":1786414342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945726003874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":33,"alternative-id":["S1389945726003874"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2026.109148","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term effects of introducing novel hypnotics to users of benzodiazepine receptor agonist hypnotics","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2026.109148","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"109148"}}