{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:31:15Z","timestamp":1790209875228,"version":"4.1.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Immunology"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.smim.2008.09.002","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T11:48:00Z","timestamp":1224071280000},"page":"8-13","source":"Crossref","is-referenced-by-count":104,"title":["Retinoic acid production by intestinal dendritic cells and its role in T-cell trafficking"],"prefix":"10.1016","volume":"21","author":[{"given":"Makoto","family":"Iwata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.smim.2008.09.002_bib1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/ajcn\/80.1.193","article-title":"Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles","volume":"80","author":"Caulfield","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib2","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/S0140-6736(86)91157-8","article-title":"Impact of vitamin A supplementation on childhood mortality. A randomised controlled community trial","volume":"1","author":"Sommer","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.smim.2008.09.002_bib3","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1136\/bmj.304.6821.207","article-title":"Childhood mortality after a high dose of vitamin A in a high risk population","volume":"304","author":"Daulaire","year":"1992","journal-title":"BMJ"},{"key":"10.1016\/j.smim.2008.09.002_bib4","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1136\/bmj.306.6874.366","article-title":"Vitamin A supplementation in infectious diseases: a meta-analysis","volume":"306","author":"Glasziou","year":"1993","journal-title":"BMJ"},{"key":"10.1016\/j.smim.2008.09.002_bib5","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0140-6736(94)92998-X","article-title":"Effect of vitamin A supplementation on diarrhoea and acute lower-respiratory-tract infections in young children in Brazil","volume":"344","author":"Barreto","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.smim.2008.09.002_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1136\/adc.77.3.191","article-title":"Vitamin A prophylaxis","volume":"77","author":"Sommer","year":"1997","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.smim.2008.09.002_bib7","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1128\/CMR.18.3.446-464.2005","article-title":"Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes","volume":"18","author":"Villamor","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.smim.2008.09.002_bib8","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1093\/jn\/127.7.1297","article-title":"Retinoic acid stimulates early cellular proliferation in the adapting remnant rat small intestine after partial resection","volume":"127","author":"Wang","year":"1997","journal-title":"J Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib9","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/jn\/110.1.178","article-title":"The prevalence, metabolism and migration of goblet cells in rat intestine following the induction of rapid, synchronous vitamin A deficiency","volume":"110","author":"Rojanapo","year":"1980","journal-title":"J Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib10","first-page":"127","article-title":"Impaired local immune response in vitamin A-deficient rats","volume":"40","author":"Sirisinha","year":"1980","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib11","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1093\/jn\/129.5.934","article-title":"Vitamin A prevents the decline in immunoglobulin A and Th2 cytokine levels in small intestinal mucosa of protein-malnourished mice","volume":"129","author":"Nikawa","year":"1999","journal-title":"J Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib12","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/sj.bjp.0703345","article-title":"Retinoid-mediated inhibition of interleukin-12 production in mouse macrophages suppresses Th1 cytokine profile in CD4+ T cells","volume":"130","author":"Kang","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.smim.2008.09.002_bib13","doi-asserted-by":"crossref","first-page":"3736","DOI":"10.1093\/jn\/132.12.3736","article-title":"Retinoic acid enhances the T helper 2 cell development that is essential for robust antibody responses through its action on antigen-presenting cells","volume":"132","author":"Hoag","year":"2002","journal-title":"J Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib14","doi-asserted-by":"crossref","first-page":"4495","DOI":"10.4049\/jimmunol.168.9.4495","article-title":"Vitamin A enhances in vitro Th2 development via retinoid X receptor pathway","volume":"168","author":"Stephensen","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib15","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1093\/intimm\/dxg101","article-title":"Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors","volume":"15","author":"Iwata","year":"2003","journal-title":"Int Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1471-2172-7-27","article-title":"Direct and indirect effects of retinoic acid on human Th2 cytokine and chemokine expression by human T lymphocytes","volume":"7","author":"Dawson","year":"2006","journal-title":"BMC Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib17","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.smim.2008.06.005","article-title":"Regulation of B cell proliferation and differentiation by retinoic acid","volume":"21","author":"Ertesv\u00e5g","year":"2009","journal-title":"Semin Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib18","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.smim.2008.08.004","article-title":"Augmentation of antibody responses by retinoic acid and costimulatory molecules","volume":"21","author":"Ross","year":"2009","journal-title":"Semin Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib19","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.immuni.2004.08.011","article-title":"Retinoic acid imprints gut-homing specificity on T cells","volume":"21","author":"Iwata","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2008.09.002_bib20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1146\/annurev.nutr.25.050304.092614","article-title":"Mechanisms of digestion and absorption of dietary vitamin A","volume":"25","author":"Harrison","year":"2005","journal-title":"Annu Rev Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib21","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1126\/science.1132742","article-title":"Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells","volume":"314","author":"Mora","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.smim.2008.09.002_bib22","first-page":"1","article-title":"Impaired intestinal localization of mesenteric lymphoblasts associated with vitamin A deficiency and protein-calorie malnutrition","volume":"45","author":"McDermott","year":"1982","journal-title":"Immunology"},{"key":"10.1016\/j.smim.2008.09.002_bib23","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1046\/j.1365-2249.2002.02009.x","article-title":"Loss of ileal IgA+ plasma cells and of CD4+ lymphocytes in ileal Peyer's patches of vitamin A deficient rats","volume":"130","author":"Bjersing","year":"2002","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib24","doi-asserted-by":"crossref","first-page":"838S","DOI":"10.1093\/jn\/127.5.838S","article-title":"Components of the AIN-93 diets as improvements in the AIN-76A diet","volume":"127","author":"Reeves","year":"1997","journal-title":"J Nutr"},{"key":"10.1016\/j.smim.2008.09.002_bib25","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0065-2776(08)60022-X","article-title":"Lymphocyte trafficking and regional immunity","volume":"72","author":"Butcher","year":"1999","journal-title":"Adv Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib26","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1056\/NEJM200010053431407","article-title":"T-cell function and migration. Two sides of the same coin","volume":"343","author":"von Andrian","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.smim.2008.09.002_bib27","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1126\/science.1058867","article-title":"Preferential localization of effector memory cells in nonlymphoid tissue","volume":"291","author":"Masopust","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.smim.2008.09.002_bib28","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1084\/jem.148.6.1661","article-title":"The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions","volume":"148","author":"Guy-Grand","year":"1978","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib29","doi-asserted-by":"crossref","first-page":"5173","DOI":"10.4049\/jimmunol.162.9.5173","article-title":"Differential homing commitments of antigen-specific T cells after oral or parenteral immunization in humans","volume":"162","author":"Kantele","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib30","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1172\/JCI0215988","article-title":"CCL25 mediates the localization of recently activated CD8\u03b1\u03b2+ lymphocytes to the small-intestinal mucosa","volume":"110","author":"Svensson","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.smim.2008.09.002_bib31","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.4049\/jimmunol.152.7.3282","article-title":"Role of \u03b14-integrins in lymphocyte homing to mucosal tissues in vivo","volume":"152","author":"Hamann","year":"1994","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib32","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1084\/jem.194.10.1541","article-title":"CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin","volume":"194","author":"Reiss","year":"2001","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib33","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/nri1354","article-title":"Lymphocyte trafficking across high endothelial venules: dogmas and enigmas","volume":"4","author":"Miyasaka","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib34","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1083\/jcb.127.5.1485","article-title":"Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow","volume":"127","author":"Alon","year":"1994","journal-title":"J Cell Biol"},{"key":"10.1016\/j.smim.2008.09.002_bib35","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1021\/ac702030f","article-title":"Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometry","volume":"80","author":"Kane","year":"2008","journal-title":"Anal Chem"},{"key":"10.1016\/j.smim.2008.09.002_bib36","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1046\/j.1523-1747.2002.01816.x","article-title":"High albumin levels restrict the kinetics of 13-cis retinoic acid uptake and intracellular isomerization to all-trans retinoic acid and inhibit its anti-proliferative effect on SZ95 sebocytes","volume":"119","author":"Tsukada","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.smim.2008.09.002_bib37","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.smim.2008.08.002","article-title":"Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells","volume":"21","author":"Mora","year":"2009","journal-title":"Semin Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib38","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1182\/blood.V94.7.2533.419k37_2533_2536","article-title":"TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6\/CCR9 as a specific receptor","volume":"94","author":"Youn","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.smim.2008.09.002_bib39","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1084\/jem.190.9.1241","article-title":"Human G protein-coupled receptor GPR-9-6\/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis","volume":"190","author":"Zabel","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib40","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1182\/blood.V97.4.850","article-title":"Expression of CCR9 \u03b2-chemokine receptor is modulated in thymocyte differentiation and is selectively maintained in CD8+ T cells from secondary lymphoid organs","volume":"97","author":"Carramolino","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.smim.2008.09.002_bib41","doi-asserted-by":"crossref","first-page":"5069","DOI":"10.4049\/jimmunol.165.9.5069","article-title":"The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system","volume":"165","author":"Papadakis","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib42","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/nature01726","article-title":"Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells","volume":"424","author":"Mora","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.smim.2008.09.002_bib43","doi-asserted-by":"crossref","first-page":"3668","DOI":"10.4049\/jimmunol.173.6.3668","article-title":"CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells","volume":"173","author":"Hieshima","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib44","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.4049\/jimmunol.180.3.1609","article-title":"Colonic patches direct the cross-talk between systemic compartments and large intestine independently of innate immunity","volume":"180","author":"Chang","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib45","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1080\/10739680701409993","article-title":"CXCL12 and CCL20 play a significant role in mucosal T-lymphocyte adherence to intestinal microvessels in mice","volume":"14","author":"Oyama","year":"2007","journal-title":"Microcirculation"},{"key":"10.1016\/j.smim.2008.09.002_bib46","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1002\/eji.200425817","article-title":"Dendritic cells govern induction and reprogramming of polarized tissue-selective homing receptor patterns of T cells: important roles for soluble factors and tissue microenvironments","volume":"35","author":"Dudda","year":"2005","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib47","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1600-065X.2006.00482.x","article-title":"Generation of gut-homing T cells and their localization to the small intestinal mucosa","volume":"215","author":"Johansson-Lindbom","year":"2007","journal-title":"Immunol Rev"},{"key":"10.1016\/j.smim.2008.09.002_bib48","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/nm1587","article-title":"Retinaldehyde represses adipogenesis and diet-induced obesity","volume":"13","author":"Ziouzenkova","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.smim.2008.09.002_bib49","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0092-8674(95)90202-3","article-title":"Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?","volume":"83","author":"Kastner","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.smim.2008.09.002_bib50","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.cell.2007.02.050","article-title":"Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors","volume":"129","author":"Schug","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.smim.2008.09.002_bib51","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.smim.2008.07.002","article-title":"Regulation of CD8+ T cell functions by RAR\u03b3","volume":"21","author":"Gordy","year":"2009","journal-title":"Semin Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib52","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1002\/1521-4141(200205)32:5<1445::AID-IMMU1445>3.0.CO;2-E","article-title":"Intestinal dendritic cells increase T Cell expression of \u03b14\u03b27 integrin","volume":"32","author":"Stagg","year":"2002","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib53","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1084\/jem.20031244","article-title":"Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant","volume":"198","author":"Johansson-Lindbom","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib54","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1388-1981(99)00117-1","article-title":"Interactions of retinoid binding proteins and enzymes in retinoid metabolism","volume":"1440","author":"Napoli","year":"1999","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.smim.2008.09.002_bib55","doi-asserted-by":"crossref","first-page":"4315","DOI":"10.1046\/j.1432-1327.2000.01497.x","article-title":"Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid","volume":"267","author":"Duester","year":"2000","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.smim.2008.09.002_bib56","doi-asserted-by":"crossref","first-page":"15360","DOI":"10.1074\/jbc.274.22.15360","article-title":"Identification of a novel class of retinoic acid receptor \u03b2-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells","volume":"274","author":"Li","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.smim.2008.09.002_bib57","doi-asserted-by":"crossref","first-page":"4222","DOI":"10.1021\/jm9704309","article-title":"Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers","volume":"40","author":"Umemiya","year":"1997","journal-title":"J Med Chem"},{"key":"10.1016\/j.smim.2008.09.002_bib58","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1084\/jem.20051100","article-title":"Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing","volume":"202","author":"Johansson-Lindbom","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib59","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1084\/jem.20070590","article-title":"A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-\u03b2 and retinoic acid-dependent mechanism","volume":"204","author":"Coombes","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib60","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/ni.1622","article-title":"Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5","volume":"9","author":"Uematsu","year":"2008","journal-title":"Nat Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib61","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1038\/ni1511","article-title":"Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses","volume":"8","author":"Denning","year":"2007","journal-title":"Nat Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib62","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.smim.2008.07.007","article-title":"Retinoic acid dependent regulation of immune responses by dendritic cells and macrophages","volume":"21","author":"Manicassamy","year":"2009","journal-title":"Semin Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib63","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s004410000281","article-title":"Localization of retinal dehydrogenase type 1 in the stomach and intestine","volume":"302","author":"Frota-Ruchon","year":"2000","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.smim.2008.09.002_bib64","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1111\/j.1742-4658.2007.05665.x","article-title":"High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract: implications for Parkinson's disease","volume":"274","author":"Westerlund","year":"2007","journal-title":"FEBS J"},{"key":"10.1016\/j.smim.2008.09.002_bib65","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/nature06033","article-title":"Regulation of IgA production by naturally occurring TNF\/iNOS-producing dendritic cells","volume":"448","author":"Tezuka","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.smim.2008.09.002_bib66","doi-asserted-by":"crossref","first-page":"4361","DOI":"10.4049\/jimmunol.180.7.4361","article-title":"Cutting edge: Langerin+ dendritic cells in the mesenteric lymph node set the stage for skin and gut immune system cross-talk","volume":"180","author":"Chang","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib67","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1084\/jem.20070602","article-title":"Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid","volume":"204","author":"Sun","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib68","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1126\/science.1145697","article-title":"Reciprocal TH17 regulatory T cell differentiation mediated by retinoic acid","volume":"317","author":"Mucida","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.smim.2008.09.002_bib69","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1084\/jem.20070719","article-title":"All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation","volume":"204","author":"Benson","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib70","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1002\/eji.200737621","article-title":"Activation of retinoic acid receptor-\u03b1 favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation","volume":"37","author":"Schambach","year":"2007","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib71","doi-asserted-by":"crossref","first-page":"3724","DOI":"10.4049\/jimmunol.179.6.3724","article-title":"Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells","volume":"179","author":"Kang","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib72","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1084\/jem.20071251","article-title":"Oral tolerance: is it all retinoic acid?","volume":"204","author":"von Boehmer","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib73","doi-asserted-by":"crossref","first-page":"416910","DOI":"10.1155\/2008\/416910","article-title":"Regulation of FoxP3 regulatory T cells and Th17 cells by retinoids","volume":"2008","author":"Kim","year":"2008","journal-title":"Clin Dev Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib74","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.smim.2008.08.001","article-title":"From the diet to the nucleus: vitamin A and TGF-\u03b2 join efforts at the mucosal interface of the intestine","volume":"21","author":"Mucida","year":"2009","journal-title":"Semin Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib75","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1002\/eji.200636575","article-title":"Induction of organ-selective CD4+ regulatory T cell homing","volume":"37","author":"Siewert","year":"2007","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib76","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1084\/jem.20041645","article-title":"Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues","volume":"201","author":"Mora","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib77","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1038\/sj.emboj.7601181","article-title":"Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites","volume":"25","author":"Huq","year":"2006","journal-title":"EMBO J"},{"key":"10.1016\/j.smim.2008.09.002_bib78","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1084\/jem.20060141","article-title":"PPAR\u03b3 controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells","volume":"203","author":"Szatmari","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2008.09.002_bib79","doi-asserted-by":"crossref","first-page":"3504","DOI":"10.4049\/jimmunol.179.6.3504","article-title":"In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid","volume":"179","author":"Saurer","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib80","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1042\/bj2440489","article-title":"Terminal-group oxidation of retinol by mouse epidermis. Inhibition in vitro and in vivo","volume":"244","author":"Connor","year":"1987","journal-title":"Biochem J"},{"key":"10.1016\/j.smim.2008.09.002_bib81","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1016\/0006-2952(88)90030-5","article-title":"Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde","volume":"37","author":"Russo","year":"1988","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.smim.2008.09.002_bib82","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/dbio.2000.9979","article-title":"Retinoic acid-mediated gene expression in transgenic reporter zebrafish","volume":"229","author":"Perz-Edwards","year":"2001","journal-title":"Dev Biol"},{"key":"10.1016\/j.smim.2008.09.002_bib83","doi-asserted-by":"crossref","first-page":"3585","DOI":"10.1021\/jf063472r","article-title":"Chemical and physical stability of citral and limonene in sodium dodecyl sulfate-chitosan and gum arabic-stabilized oil-in-water emulsions","volume":"55","author":"Djordjevic","year":"2007","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.smim.2008.09.002_bib84","doi-asserted-by":"crossref","first-page":"6501","DOI":"10.4049\/jimmunol.180.10.6501","article-title":"Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells","volume":"180","author":"Elgueta","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib85","doi-asserted-by":"crossref","first-page":"4708","DOI":"10.4049\/jimmunol.160.10.4708","article-title":"In situ immune response in gut-associated lymphoid tissue (GALT) following oral antigen in TCR-transgenic mice","volume":"160","author":"Gonnella","year":"1998","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib86","doi-asserted-by":"crossref","DOI":"10.1182\/blood-2008-01-135251","article-title":"Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid","author":"Spiegl","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.smim.2008.09.002_bib87","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1006\/dbio.1999.9487","article-title":"Complementary domains of retinoic acid production and degradation in the early chick embryo","volume":"216","author":"Swindell","year":"1999","journal-title":"Dev Biol"},{"key":"10.1016\/j.smim.2008.09.002_bib88","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/(SICI)1521-1878(199910)21:10<809::AID-BIES2>3.0.CO;2-0","article-title":"Heads or tails? Retinoic acid will decide","volume":"21","author":"Maden","year":"1999","journal-title":"Bioessays"},{"key":"10.1016\/j.smim.2008.09.002_bib89","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.1210\/en.141.10.3638","article-title":"Expression of enzymes synthesizing (aldehyde dehydrogenase 1 and reinaldehyde dehydrogenase 2) and metabolizaing (Cyp26) retinoic acid in the mouse female reproductive system","volume":"141","author":"Vermot","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.smim.2008.09.002_bib90","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.mce.2007.09.010","article-title":"LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol","volume":"280","author":"Lane","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.smim.2008.09.002_bib91","doi-asserted-by":"crossref","first-page":"6908","DOI":"10.1074\/jbc.275.10.6908","article-title":"4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7","volume":"275","author":"Samokyszyn","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.smim.2008.09.002_bib92","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/1389200033336900","article-title":"Retinoic acid metabolism and mechanism of action: a review","volume":"4","author":"Marill","year":"2003","journal-title":"Curr Drug Metab"},{"key":"10.1016\/j.smim.2008.09.002_bib93","doi-asserted-by":"crossref","first-page":"3302","DOI":"10.4049\/jimmunol.149.10.3302","article-title":"Retinoic acids inhibit activation-induced apoptosis in T cell hybridomas and thymocytes","volume":"149","author":"Iwata","year":"1992","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2008.09.002_bib94","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0076-6879(86)23015-3","article-title":"Quantification of physiological levels of retinoic acid","volume":"123","author":"Napoli","year":"1986","journal-title":"Methods Enzymol"}],"container-title":["Seminars in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044532308000948?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044532308000948?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T09:50:39Z","timestamp":1684576239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1044532308000948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":94,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S1044532308000948"],"URL":"https:\/\/doi.org\/10.1016\/j.smim.2008.09.002","relation":{},"ISSN":["1044-5323"],"issn-type":[{"value":"1044-5323","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}