{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:28:49Z","timestamp":1791404929856,"version":"4.3.3"},"reference-count":159,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T00:00:00Z","timestamp":1405036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Immunology"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.smim.2014.06.003","type":"journal-article","created":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T16:45:25Z","timestamp":1405097125000},"page":"329-340","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":249,"title":["Host protective roles of type 2 immunity: Parasite killing and tissue repair, flip sides of the same coin"],"prefix":"10.1016","volume":"26","author":[{"given":"Judith E.","family":"Allen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara E.","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.smim.2014.06.003_bib0005","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nri2992","article-title":"Diversity and dialogue in immunity to helminths","volume":"11","author":"Allen","year":"2011","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0010","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nri2199","article-title":"Protective immune mechanisms in helminth infection","volume":"7","author":"Anthony","year":"2007","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0015","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/ni.2617","article-title":"TH2, allergy and group 2 innate lymphoid cells","volume":"14","author":"Licona-Lim\u00f3n","year":"2013","journal-title":"Nat Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0020","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1600-065X.2008.00713.x","article-title":"Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites","volume":"226","author":"Saenz","year":"2008","journal-title":"Immunol Rev"},{"key":"10.1016\/j.smim.2014.06.003_bib0025","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/nri3476","article-title":"Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths","volume":"13","author":"Gause","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0030","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.chom.2014.02.001","article-title":"A2B adenosine receptor induces protective antihelminth Type 2 immune responses","volume":"15","author":"Patel","year":"2014","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.smim.2014.06.003_bib0035","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3389\/fimmu.2012.00082","article-title":"Mast cells respond to cell injury through the recognition of IL-33","volume":"3","author":"Lunderius-Andersson","year":"2012","journal-title":"Front Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0040","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S1074-7613(04)00026-3","article-title":"Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production","volume":"20","author":"Voehringer","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0045","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1128\/IAI.72.1.398-407.2004","article-title":"Both free-living and parasitic nematodes induce a characteristic Th2 response that is dependent on the presence of intact glycans","volume":"72","author":"Tawill","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molbiopara.2009.04.008","article-title":"Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity","volume":"167","author":"Hewitson","year":"2009","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.smim.2014.06.003_bib0055","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nri1412","article-title":"Fibrotic disease and the T(H)1\/T(H)2 paradigm","volume":"4","author":"Wynn","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0060","doi-asserted-by":"crossref","first-page":"e1002003","DOI":"10.1371\/journal.ppat.1002003","article-title":"Evolution of th2 immunity: a rapid repair response to tissue destructive pathogens","volume":"7","author":"Allen","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0065","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.immunol.21.120601.141142","article-title":"IL-13 effector functions","volume":"21","author":"Wynn","year":"2003","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0070","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S1074-7613(00)80477-X","article-title":"IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis","volume":"8","author":"Urban","year":"1998","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0075","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fimmu.2013.00074","article-title":"Development of CD4T cell dependent immunity against N. brasiliensis infection","volume":"4","author":"Harvie","year":"2013","journal-title":"Front Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0080","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/nm.2628","article-title":"An essential role for T(H)2-type responses in limiting acute tissue damage during experimental helminth infection","volume":"18","author":"Chen","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0085","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/eji.200737827","article-title":"Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages","volume":"38","author":"Marsland","year":"2008","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0090","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1128\/IAI.00192-08","article-title":"Hookworm-induced persistent changes to the immunological environment of the lung","volume":"76","author":"Reece","year":"2008","journal-title":"Infect Immun"},{"issue":"Suppl 2","key":"10.1016\/j.smim.2014.06.003_bib0095","doi-asserted-by":"crossref","first-page":"i101","DOI":"10.1136\/annrheumdis-2011-200589","article-title":"IL-33: a Janus cytokine","volume":"71","author":"Liew","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.smim.2014.06.003_bib0100","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/nature08636","article-title":"Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells","volume":"463","author":"Moro","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.smim.2014.06.003_bib0105","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/nature08900","article-title":"Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity","volume":"464","author":"Neill","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.smim.2014.06.003_bib0110","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1182\/blood-2012-07-442640","article-title":"The biology of nematode- and IL4R\u03b1-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics","volume":"120","author":"Thomas","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.smim.2014.06.003_bib0115","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.immuni.2009.05.007","article-title":"Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases","volume":"31","author":"L\u00fcthi","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0120","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1084\/jem.191.6.1069","article-title":"T1\/ST2-deficient mice demonstrate the importance of T1\/ST2 in developing primary T helper cell type 2 responses","volume":"191","author":"Townsend","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0125","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.molimm.2013.05.225","article-title":"IL-33 accelerates cutaneous wound healing involved in upregulation of alternatively activated macrophages","volume":"56","author":"Yin","year":"2013","journal-title":"Mol Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0130","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1755-1536-5-18","article-title":"Emerging role of the interleukin (IL)-33\/ST2 axis in gut mucosal wound healing and fibrosis","volume":"5","author":"Lopetuso","year":"2012","journal-title":"Fibrogenesis Tissue Repair"},{"key":"10.1016\/j.smim.2014.06.003_bib0135","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.immuni.2013.07.018","article-title":"Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis","volume":"39","author":"McHedlidze","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0140","doi-asserted-by":"crossref","first-page":"6469","DOI":"10.4049\/jimmunol.0901575","article-title":"IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation","volume":"183","author":"Kurowska-Stolarska","year":"2009","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0145","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.4049\/jimmunol.180.4.2443","article-title":"IL-33 a potent inducer of adaptive immunity to intestinal nematodes","volume":"180","author":"Humphreys","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0150","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1073\/pnas.1206587110","article-title":"IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms","volume":"110","author":"Hung","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.smim.2014.06.003_bib0155","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1084\/jem.20051615","article-title":"Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion","volume":"203","author":"Fallon","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0160","doi-asserted-by":"crossref","first-page":"11489","DOI":"10.1073\/pnas.1003988107","article-title":"Systemically dispersed innate IL-13-expressing cells in type 2 immunity","volume":"107","author":"Price","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.smim.2014.06.003_bib0165","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1084\/jem.20051496","article-title":"Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract","volume":"203","author":"Owyang","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0170","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1128\/IAI.00646-13","article-title":"Interleukin-25 (IL-25) promotes efficient protective immunity against Trichinella spiralis infection by enhancing the antigen-specific IL-9 response","volume":"81","author":"Angkasekwinai","year":"2013","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0175","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1053\/j.gastro.2009.02.049","article-title":"Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut","volume":"136","author":"Caruso","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.smim.2014.06.003_bib0180","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/cmi.2008.53","article-title":"Inhibitory effect of recombinant IL-25 on the development of dextran sulfate sodium-induced experimental colitis in mice","volume":"5","author":"Mchenga","year":"2008","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0185","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/S1074-7613(01)00243-6","article-title":"IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo","volume":"15","author":"Fort","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0190","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1073\/pnas.1315854111","article-title":"IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis","volume":"111","author":"Hams","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.smim.2014.06.003_bib0195","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/ni.1852","article-title":"Sensing the outside world: TSLP regulates barrier immunity","volume":"11","author":"Ziegler","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0200","doi-asserted-by":"crossref","DOI":"10.1002\/hep.27169","article-title":"Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice","author":"Proctor","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.smim.2014.06.003_bib0205","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/glia.22662","article-title":"Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system","volume":"62","author":"Kitic","year":"2014","journal-title":"Glia"},{"key":"10.1016\/j.smim.2014.06.003_bib0210","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1084\/jem.20051135","article-title":"TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand","volume":"202","author":"Ito","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0215","article-title":"Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages","author":"Han","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0220","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1084\/jem.20081499","article-title":"TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis","volume":"206","author":"Taylor","year":"2009","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0225","doi-asserted-by":"crossref","first-page":"13968","DOI":"10.1073\/pnas.0906367106","article-title":"Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function","volume":"106","author":"Massacand","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.smim.2014.06.003_bib0230","doi-asserted-by":"crossref","first-page":"6452","DOI":"10.4049\/jimmunol.0900181","article-title":"Regulation of helminth-induced Th2 responses by thymic stromal lymphopoietin","volume":"182","author":"Ramalingam","year":"2009","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0235","doi-asserted-by":"crossref","first-page":"7232","DOI":"10.4049\/jimmunol.1100504","article-title":"IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin","volume":"186","author":"Oh","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0240","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.coi.2012.06.003","article-title":"Susceptibility and immunity to helminth parasites","volume":"24","author":"Maizels","year":"2012","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0245","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.coi.2013.02.010","article-title":"Development and function of group 2 innate lymphoid cells","volume":"25","author":"Walker","year":"2013","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0250","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.immuni.2014.01.011","article-title":"Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation","volume":"40","author":"Halim","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0255","doi-asserted-by":"crossref","first-page":"443","DOI":"10.4049\/jimmunol.169.1.443","article-title":"New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25","volume":"169","author":"Hurst","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0260","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1084\/jem.20130071","article-title":"IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation","volume":"210","author":"Turner","year":"2013","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0265","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.immuni.2010.05.007","article-title":"Alternative activation of macrophages: mechanism and functions","volume":"32","author":"Gordon","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0270","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.coi.2007.07.002","article-title":"Alternatively activated macrophages in helminth infections","volume":"19","author":"Kreider","year":"2007","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0275","doi-asserted-by":"crossref","first-page":"e1003771","DOI":"10.1371\/journal.ppat.1003771","article-title":"Antibodies trap tissue migrating helminth larvae and prevent tissue damage by driving IL-4R\u03b1-independent alternative differentiation of macrophages","volume":"9","author":"Bieren","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0280","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/icb.2013.109","article-title":"Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection","volume":"92","author":"Filbey","year":"2014","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0285","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0014-4894(02)00015-2","article-title":"Brugian infections in the peritoneal cavities of laboratory mice: kinetics of infection and cellular responses","volume":"100","author":"Rajan","year":"2002","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.smim.2014.06.003_bib0290","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1046\/j.1365-3024.2001.00394.x","article-title":"Divergent roles for macrophages in lymphatic filariasis","volume":"23","author":"Allen","year":"2001","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0295","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1128\/IAI.00625-13","article-title":"Human and mouse macrophages collaborate with neutrophils to kill larval Strongyloides stercoralis","volume":"81","author":"Bonne-Ann\u00e9e","year":"2013","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0300","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/nm1451","article-title":"Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites","volume":"12","author":"Anthony","year":"2006","journal-title":"Nat Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0305","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1053\/j.gastro.2008.03.077","article-title":"Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages","volume":"135","author":"Zhao","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.smim.2014.06.003_bib0310","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1084\/jem.20121999","article-title":"IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1","volume":"210","author":"Jenkins","year":"2013","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0315","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1084\/jem.20082048","article-title":"Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung","volume":"206","author":"Nair","year":"2009","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0320","doi-asserted-by":"crossref","first-page":"e1000393","DOI":"10.1371\/journal.ppat.1000393","article-title":"Retnla (relmalpha\/fizz1) suppresses helminth-induced Th2-type immunity","volume":"5","author":"Pesce","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0325","doi-asserted-by":"crossref","first-page":"e84763","DOI":"10.1371\/journal.pone.0084763","article-title":"Role of macrophages in the altered epithelial function during a Type 2 immune response induced by enteric nematode infection","volume":"9","author":"Notari","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.smim.2014.06.003_bib0330","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature05746","article-title":"Chitin induces accumulation in tissue of innate immune cells associated with allergy","volume":"447","author":"Reese","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.smim.2014.06.003_bib0335","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/path.4133","article-title":"Macrophage plasticity and polarization in tissue repair and remodelling","volume":"229","author":"Mantovani","year":"2013","journal-title":"J Pathol"},{"key":"10.1016\/j.smim.2014.06.003_bib0340","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1476-5381.2009.00374.x","article-title":"Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives","volume":"158","author":"Maarsingh","year":"2009","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.smim.2014.06.003_bib0345","doi-asserted-by":"crossref","first-page":"3926","DOI":"10.4049\/jimmunol.179.6.3926","article-title":"Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection","volume":"179","author":"Loke","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0350","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1189\/jlb.72.1.72","article-title":"Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation","volume":"72","author":"Hung","year":"2002","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0355","doi-asserted-by":"crossref","first-page":"240ra76-6","DOI":"10.1126\/scitranslmed.3007096","article-title":"Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis","volume":"6","author":"Zhou","year":"2014","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0360","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1161\/01.RES.0000073999.07698.33","article-title":"FIZZ1\/RELMalpha a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties","volume":"92","author":"Teng","year":"2003","journal-title":"Circ Res"},{"key":"10.1016\/j.smim.2014.06.003_bib0365","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1189\/jlb.0504288","article-title":"IL-4-induced macrophage-derived IGF-I protects myofibroblasts from apoptosis following growth factor withdrawal","volume":"76","author":"Wynes","year":"2004","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0370","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1083\/jcb.201301081","article-title":"M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway","volume":"202","author":"Madsen","year":"2013","journal-title":"J Cell Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0375","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/sj.jid.5700701","article-title":"Inflammation in wound repair: molecular and cellular mechanisms","volume":"127","author":"Eming","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.smim.2014.06.003_bib0380","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1002\/(SICI)1521-4141(200004)30:4<1127::AID-IMMU1127>3.0.CO;2-#","article-title":"Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of na\u00efve CD4(+) T cells","volume":"30","author":"Loke","year":"2000","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0385","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S1074-7613(00)80014-X","article-title":"Other functions, other genes: alternative activation of antigen-presenting cells","volume":"10","author":"Goerdt","year":"1999","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0390","doi-asserted-by":"crossref","first-page":"3656","DOI":"10.1128\/IAI.70.7.3656-3664.2002","article-title":"Chronic helminth infection induces alternatively activated macrophages expressing high levels of CCR5 with low interleukin-12 production and Th2-biasing ability","volume":"70","author":"Rodr\u00edguez-Sosa","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0395","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.4049\/jimmunol.149.4.1283","article-title":"IL-4 reciprocally regulates IL-1 and IL-1 receptor antagonist expression in human monocytes","volume":"149","author":"Fenton","year":"1992","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0400","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.it.2004.09.015","article-title":"The chemokine system in diverse forms of macrophage activation and polarization","volume":"25","author":"Mantovani","year":"2004","journal-title":"Trends Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0405","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2172-3-7","article-title":"IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype","volume":"3","author":"Loke","year":"2002","journal-title":"BMC Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0410","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S1074-7613(04)00107-4","article-title":"Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology","volume":"20","author":"Herbert","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0415","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.immunol.24.021605.090737","article-title":"Transforming growth factor-beta regulation of immune responses","volume":"24","author":"Li","year":"2006","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0420","doi-asserted-by":"crossref","first-page":"15267","DOI":"10.1074\/jbc.M410638200","article-title":"A role for the mouse 12\/15-lipoxygenase pathway in promoting epithelial wound healing and host defense","volume":"280","author":"Gronert","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.smim.2014.06.003_bib0425","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.plipres.2006.02.003","article-title":"Inflammation and immune regulation by 12\/15-lipoxygenases","volume":"45","author":"K\u00fchn","year":"2006","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.smim.2014.06.003_bib0430","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1002\/eji.201242929","article-title":"T-cell-derived, but not B-cell-derived, IL-10 suppresses antigen-specific T-cell responses in Litomosoides sigmodontis-infected mice","volume":"43","author":"Haben","year":"2013","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0435","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.immuni.2014.03.012","article-title":"Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis","volume":"40","author":"Zigmond","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0440","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1189\/jlb.0413236","article-title":"Extrinsic and intrinsic control of macrophage inflammatory responses","volume":"94","author":"Cohen","year":"2013","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0445","doi-asserted-by":"crossref","first-page":"1242974","DOI":"10.1126\/science.1242974","article-title":"Beyond stem cells: self-renewal of differentiated macrophages","volume":"342","author":"Sieweke","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.smim.2014.06.003_bib0450","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1084\/jem.20131199","article-title":"Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF","volume":"210","author":"Guilliams","year":"2013","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0455","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.immuni.2012.08.026","article-title":"Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells","volume":"37","author":"Zigmond","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0460","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/mi.2012.89","article-title":"Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6C(hi) monocyte precursors","volume":"6","author":"Bain","year":"2012","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0465","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.immuni.2013.04.004","article-title":"Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes","volume":"38","author":"Hashimoto","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0470","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1126\/science.1204351","article-title":"Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation","volume":"332","author":"Jenkins","year":"2011","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.smim.2014.06.003_bib0475","doi-asserted-by":"crossref","first-page":"e1004080","DOI":"10.1371\/journal.ppat.1004080","article-title":"Ly6Chigh monocytes become alternatively activated macrophages in Schistosome granulomas with help from CD4+ cells","volume":"10","author":"Girgis","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0480","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004282","article-title":"Ly6Chi monocyte recruitment is responsible for Th2 associated host-protective macrophage accumulation in liver inflammation due to schistosomiasis","author":"Nascimento","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0485","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1182\/blood-2013-08-520619","article-title":"Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct","volume":"123","author":"Gundra","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.smim.2014.06.003_bib0490","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1146\/annurev.immunol.24.021605.090720","article-title":"The eosinophil","volume":"24","author":"Rothenberg","year":"2006","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0495","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1046\/j.1365-3024.2001.00352.x","article-title":"Involvement of complement and fibronectin in eosinophil-mediated damage to Nippostrongylus brasiliensis larvae","volume":"23","author":"Shin","year":"2001","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0500","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.4049\/jimmunol.144.8.3166","article-title":"In vitro killing of microfilariae of Brugia-Pahangi and Brugia-Malayi by eosinophil granule proteins","volume":"144","author":"Hamann","year":"1990","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0505","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/256727a0","article-title":"Eosinophils as mediators of antibody-dependent damage to schistosomula","volume":"256","author":"Butterworth","year":"1975","journal-title":"Nature"},{"key":"10.1016\/j.smim.2014.06.003_bib0510","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1365-3024.1998.00132.x","article-title":"Eosinophil-mediated killing of Haemonchus contortus larvae: effect of eosinophil activation and role of antibody, complement and interleukin-5","volume":"20","author":"Rainbird","year":"1998","journal-title":"Parasite Immunol"},{"issue":"Suppl 1","key":"10.1016\/j.smim.2014.06.003_bib0515","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1159\/000237717","article-title":"Protective roles of eosinophils in Nippostrongylus brasiliensis infection","volume":"114","author":"Shin","year":"1997","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0520","doi-asserted-by":"crossref","first-page":"5315","DOI":"10.1128\/IAI.67.10.5315-5323.1999","article-title":"Trapping and immobilization of Nippostrongylus brasiliensis larvae at the site of inoculation in primary infections of interleukin-5 transgenic mice","volume":"67","author":"Daly","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0525","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.ijpara.2007.04.006","article-title":"Impaired resistance in early secondary Nippostrongylus brasiliensis infections in mice with defective eosinophilopoeisis","volume":"37","author":"Knott","year":"2007","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.smim.2014.06.003_bib0530","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1128\/IAI.72.2.810-817.2004","article-title":"Immunoglobulin E and eosinophil-dependent protective immunity to larval Onchocerca volvulus in mice immunized with irradiated larvae","volume":"72","author":"Abraham","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0535","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/PL00008258","article-title":"IL-5 is essential for vaccine-induced protection and for resolution of primary infection in murine filariasis","volume":"189","author":"Martin","year":"2000","journal-title":"Med Microbiol Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0540","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.1128\/IAI.68.5.2513-2517.2000","article-title":"Interleukin-5 is essential for vaccine-mediated immunity but not innate resistance to a filarial parasite","volume":"68","author":"Le Goff","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0545","doi-asserted-by":"crossref","first-page":"e1000525","DOI":"10.1371\/journal.pbio.1000525","article-title":"Filarial parasites develop faster and reproduce earlier in response to host immune effectors that determine filarial life expectancy","volume":"8","author":"Babayan","year":"2010","journal-title":"PLoS Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0550","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.4049\/jimmunol.145.11.3911","article-title":"Ablation of eosinophil and ige responses with Anti-IL-5 or Anti-IL-4 antibodies fails to affect immunity against Schistosoma-Mansoni in the mouse","volume":"145","author":"Sher","year":"1990","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0555","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.4049\/jimmunol.149.11.3642","article-title":"Depletion of eosinophils by anti-Il-5 monoclonal-antibody treatment of mice infected with Trichinella-Spiralis does not alter parasite burden or immunological resistance to reinfection","volume":"149","author":"Herndon","year":"1992","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0560","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1046\/j.1365-3024.1999.00200.x","article-title":"Mast cells, eosinophils and antibody-mediated cellular cytotoxicity are not critical in resistance to Trichuris muris","volume":"21","author":"Betts","year":"1999","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0565","first-page":"502","article-title":"The role of interleukin-5 in protective immunity to Strongyloides-Venezuelensis infection in mice","volume":"72","author":"Korenaga","year":"1991","journal-title":"Immunology"},{"key":"10.1016\/j.smim.2014.06.003_bib0570","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1365-3024.1993.tb00619.x","article-title":"Ablation of eosinophils with anti-IL-5 antibody enhances the survival of intracranial worms of Angiostrongylus-Cantonensis in the mouse","volume":"15","author":"Sasaki","year":"1993","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0575","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/eji.200425541","article-title":"Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection","volume":"35","author":"Simons","year":"2005","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0580","doi-asserted-by":"crossref","first-page":"e1003988","DOI":"10.1371\/journal.ppat.1003988","article-title":"Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae","volume":"10","author":"Cadman","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0585","doi-asserted-by":"crossref","first-page":"8442","DOI":"10.1128\/IAI.73.12.8442-8443.2005","article-title":"Eosinophils, but not eosinophil peroxidase or major basic protein, are important for host protection in experimental Brugia pahangi infection","volume":"73","author":"Ramalingam","year":"2005","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0590","doi-asserted-by":"crossref","first-page":"5236","DOI":"10.1128\/IAI.00329-06","article-title":"Lack of eosinophil peroxidase or major basic protein impairs defense against murine filarial infection","volume":"74","author":"Specht","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0595","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1086\/522968","article-title":"Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice","volume":"196","author":"Padigel","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.smim.2014.06.003_bib0600","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.ajpath.2011.04.025","article-title":"Eosinophils contribute to IL-4 production and shape the T-helper cytokine profile and inflammatory response in pulmonary cryptococcosis","volume":"179","author":"Piehler","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.smim.2014.06.003_bib0605","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1084\/jem.20071836","article-title":"Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma","volume":"205","author":"Walsh","year":"2008","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0610","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.2353\/ajpath.2006.060617","article-title":"Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling","volume":"169","author":"Fulkerson","year":"2006","journal-title":"Am J Pathol"},{"key":"10.1016\/j.smim.2014.06.003_bib0615","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1084\/jem.184.5.1871","article-title":"Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils","volume":"184","author":"Sabin","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0620","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1084\/jem.20052448","article-title":"Type 2 immunity is controlled by IL-4\/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system","volume":"203","author":"Voehringer","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0625","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.4049\/jimmunol.182.3.1577","article-title":"Eosinophil deficiency compromises parasite survival in chronic nematode infection","volume":"182","author":"Fabre","year":"2009","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0630","doi-asserted-by":"crossref","first-page":"417","DOI":"10.4049\/jimmunol.1101980","article-title":"Eosinophils preserve parasitic nematode larvae by regulating local immunity","volume":"188","author":"Gebreselassie","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0635","first-page":"581","article-title":"A light microscopical study of healing incised dermal wounds in rats, with special reference to eosinophil leucocytes and to the collagenous fibres of the periwound areas","volume":"58","author":"Bassett","year":"1977","journal-title":"Br J Exp Pathol"},{"key":"10.1016\/j.smim.2014.06.003_bib0640","doi-asserted-by":"crossref","first-page":"9914","DOI":"10.1073\/pnas.1304046110","article-title":"Eosinophils secrete IL-4 to facilitate liver regeneration","volume":"110","author":"Goh","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.smim.2014.06.003_bib0645","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.cell.2013.02.053","article-title":"Type 2 innate signals stimulate fibro\/adipogenic progenitors to facilitate muscle regeneration","volume":"153","author":"Heredia","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.smim.2014.06.003_bib0650","first-page":"1307","article-title":"The eosinophil as a cellular source of transforming growth factor-alpha in healing cutaneous wounds","volume":"138","author":"Todd","year":"1991","journal-title":"Am J Pathol"},{"key":"10.1016\/j.smim.2014.06.003_bib0655","first-page":"130","article-title":"Sequential expression of transforming growth-factor-alpha and factor-beta(1) by eosinophils during cutaneous wound-healing in the hamster","volume":"143","author":"Wong","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1016\/j.smim.2014.06.003_bib0660","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1002\/jcb.240450407","article-title":"Egf and Tgf-alpha in wound-healing and repair","volume":"45","author":"Schultz","year":"1991","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.smim.2014.06.003_bib0665","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/BF00402221","article-title":"Human eosinophils stimulate DNA synthesis and matrix production in dermal fibroblasts","volume":"286","author":"Birkland","year":"1994","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.smim.2014.06.003_bib0670","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1365-2249.2004.02396.x","article-title":"The effect of eosinophils on collagen gel contraction and implications for tissue remodelling","volume":"135","author":"Zagai","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0675","doi-asserted-by":"crossref","first-page":"e29815","DOI":"10.1371\/journal.pone.0029815","article-title":"Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis","volume":"7","author":"Wong","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.smim.2014.06.003_bib0680","doi-asserted-by":"crossref","first-page":"4317","DOI":"10.4049\/jimmunol.1301465","article-title":"IL-33 markedly activates murine eosinophils by an NF-(B-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop","volume":"191","author":"Bouffi","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0685","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/icb.2008.72","article-title":"IL-5-overexpressing mice exhibit eosinophilia and altered wound healing through mechanisms involving prolonged inflammation","volume":"87","author":"Leitch","year":"2009","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.smim.2014.06.003_bib0690","doi-asserted-by":"crossref","first-page":"5347","DOI":"10.4049\/jimmunol.160.11.5347","article-title":"Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase\/arginase balance: competitive regulation by CD4+ T cells correlates with Th1\/Th2 phenotype","volume":"160","author":"Munder","year":"1998","journal-title":"J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0695","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1002\/eji.200839041","article-title":"L-arginine deprivation impairs Leishmania major-specific T-cell responses","volume":"39","author":"Munder","year":"2009","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0700","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.imbio.2007.09.008","article-title":"Role of arginine metabolism in immunity and immunopathology","volume":"212","author":"Peranzoni","year":"2008","journal-title":"Immunobiology"},{"key":"10.1016\/j.smim.2014.06.003_bib0705","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/SLA.0b013e31828611f8","article-title":"The central role of arginine catabolism in T-cell dysfunction and increased susceptibility to infection after physical injury","volume":"259","author":"Zhu","year":"2014","journal-title":"Ann Surg"},{"key":"10.1016\/j.smim.2014.06.003_bib0710","doi-asserted-by":"crossref","first-page":"1602S","DOI":"10.1093\/jn\/137.6.1602S","article-title":"Arginine metabolism: boundaries of our knowledge","volume":"137","author":"Morris","year":"2007","journal-title":"J Nutr"},{"key":"10.1016\/j.smim.2014.06.003_bib0715","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1084\/jem.20130761","article-title":"The skin is an important bulwark of acquired immunity against intestinal helminths","volume":"210","author":"Obata-Ninomiya","year":"2013","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0720","doi-asserted-by":"crossref","first-page":"e1000371","DOI":"10.1371\/journal.ppat.1000371","article-title":"Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis","volume":"5","author":"Pesce","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.smim.2014.06.003_bib0725","doi-asserted-by":"crossref","first-page":"e61961","DOI":"10.1371\/journal.pone.0061961","article-title":"Role of arginase 1 from myeloid cells in th2-dominated lung inflammation","volume":"8","author":"Barron","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.smim.2014.06.003_bib0730","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1038\/ni.1671","article-title":"Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens","volume":"9","author":"Kasmi El","year":"2008","journal-title":"Nat Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0735","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1126\/science.1133715","article-title":"Amphiregulin, a TH2 cytokine enhancing resistance to nematodes","volume":"314","author":"Zaiss","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.smim.2014.06.003_bib0740","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.immuni.2012.09.023","article-title":"Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor","volume":"38","author":"Zaiss","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0745","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1126\/science.1108661","article-title":"Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion","volume":"308","author":"Cliffe","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.smim.2014.06.003_bib0750","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1038\/ni.2131","article-title":"Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus","volume":"12","author":"Monticelli","year":"2011","journal-title":"Nat Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0755","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.cell.2013.10.054","article-title":"A special population of regulatory T cells potentiates muscle repair","volume":"155","author":"Burzyn","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.smim.2014.06.003_bib0760","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1126\/science.1233632","article-title":"Role of tissue protection in lethal respiratory viral-bacterial coinfection","volume":"340","author":"Jamieson","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.smim.2014.06.003_bib0765","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1002\/hep.22437","article-title":"The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis","volume":"48","author":"Perugorria","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.smim.2014.06.003_bib0770","doi-asserted-by":"crossref","first-page":"4970","DOI":"10.1128\/IAI.00687-06","article-title":"Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages","volume":"74","author":"Reece","year":"2006","journal-title":"Infect Immun"},{"key":"10.1016\/j.smim.2014.06.003_bib0775","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.it.2010.11.005","article-title":"To B or not to B: B cells and the Th2-type immune response to helminths","volume":"32","author":"Harris","year":"2011","journal-title":"Trends Immunol"},{"key":"10.1016\/j.smim.2014.06.003_bib0780","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.immuni.2013.10.006","article-title":"Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity","volume":"39","author":"Palm","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0785","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.immuni.2013.10.005","article-title":"A beneficial role for immunoglobulin E in host defense against honeybee venom","volume":"39","author":"Marichal","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2014.06.003_bib0790","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1084\/jem.20120295","article-title":"Non-canonical alternatives: what a macrophage is 4","volume":"209","author":"Karp","year":"2012","journal-title":"J Exp Med"},{"key":"10.1016\/j.smim.2014.06.003_bib0795","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1084\/jem.20071868","article-title":"IL-33 reduces the development of atherosclerosis","volume":"205","author":"Miller","year":"2008","journal-title":"J Exp Med"}],"container-title":["Seminars in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044532314000608?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044532314000608?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T01:55:37Z","timestamp":1689386137000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1044532314000608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":159,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S1044532314000608"],"URL":"https:\/\/doi.org\/10.1016\/j.smim.2014.06.003","relation":{},"ISSN":["1044-5323"],"issn-type":[{"value":"1044-5323","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Host protective roles of type 2 immunity: Parasite killing and tissue repair, flip sides of the same coin","name":"articletitle","label":"Article Title"},{"value":"Seminars in Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.smim.2014.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}