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Biol."},{"key":"10.1016\/j.smim.2021.101510_bib0400","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/363172a0","article-title":"A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5","volume":"363","author":"Milburn","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.smim.2021.101510_bib0405","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/(SICI)1097-0134(199611)26:3<304::AID-PROT6>3.0.CO;2-D","article-title":"Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor","volume":"26","author":"Rozwarski","year":"1996","journal-title":"Proteins"},{"key":"10.1016\/j.smim.2021.101510_bib0410","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1749-6632.1994.tb39796.x","article-title":"The three-dimensional structure of human interleukin-5 at 2.4-angstroms resolution: implication for the structures of other cytokines","volume":"725","author":"Wells","year":"1994","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.smim.2021.101510_bib0415","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1126\/science.3923623","article-title":"Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins","volume":"228","author":"Wong","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.smim.2021.101510_bib0420","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0092-8674(86)90360-0","article-title":"Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3","volume":"47","author":"Yang","year":"1986","journal-title":"Cell"},{"key":"10.1016\/j.smim.2021.101510_bib0425","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1080\/1744666X.2016.1208564","article-title":"The role of interleukin 5 in asthma","volume":"12","author":"Varricchi","year":"2016","journal-title":"Expert Rev. Clin. 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Biol. Chem."},{"key":"10.1016\/j.smim.2021.101510_bib0525","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0092-8674(00)81167-8","article-title":"Jak2 is essential for signaling through a variety of cytokine receptors","volume":"93","author":"Parganas","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.smim.2021.101510_bib0530","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0092-8674(00)81166-6","article-title":"Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses","volume":"93","author":"Rodig","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.smim.2021.101510_bib0535","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.4049\/jimmunol.162.3.1496","article-title":"The mapping of the Lyn kinase binding site of the common beta subunit of IL-3\/granulocyte-macrophage colony-stimulating factor\/IL-5 receptor","volume":"162","author":"Adachi","year":"1999","journal-title":"J. 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Cell. Biol."},{"key":"10.1016\/j.smim.2021.101510_bib0580","doi-asserted-by":"crossref","first-page":"3298","DOI":"10.1182\/blood.V82.11.3298.3298","article-title":"Human granulocyte-macrophage colony-stimulating factor receptor signal transduction requires the proximal cytoplasmic domains of the alpha and beta subunits","volume":"82","author":"Weiss","year":"1993","journal-title":"Blood"},{"key":"10.1016\/j.smim.2021.101510_bib0585","first-page":"665","article-title":"Interleukin-3 production as a sensitive measure of T-lymphocyte activation in the mouse","volume":"62","author":"Dotsika","year":"1987","journal-title":"Immunology"},{"key":"10.1016\/j.smim.2021.101510_bib0590","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.87157","article-title":"IL-3 promotes the development of experimental autoimmune encephalitis","volume":"1","author":"Renner","year":"2016","journal-title":"JCI Insight"},{"key":"10.1016\/j.smim.2021.101510_bib0595","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4049\/jimmunol.141.1.151","article-title":"Identification of IL-6 as a T cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate","volume":"141","author":"Hodgkin","year":"1988","journal-title":"J. Immunol."},{"key":"10.1016\/j.smim.2021.101510_bib0600","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1084\/jem.166.5.1229","article-title":"Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies","volume":"166","author":"Cherwinski","year":"1987","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.smim.2021.101510_bib0605","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aan0829","article-title":"Regulatory T cells induce activation rather than suppression of human basophils","volume":"3","author":"Sharma","year":"2018","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.smim.2021.101510_bib0610","first-page":"778","article-title":"Involvement of interleukin-3 in delayed-type hypersensitivity","volume":"91","author":"Mach","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.smim.2021.101510_bib0615","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1172\/JCI114352","article-title":"Regulation of interleukin 3 gene induction in normal human T cells","volume":"84","author":"Guba","year":"1989","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.smim.2021.101510_bib0620","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/339064a0","article-title":"Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon RI or to calcium ionophores","volume":"339","author":"Plaut","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.smim.2021.101510_bib0625","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4049\/jimmunol.1900310","article-title":"In activated murine mast cells, NFATc2 is critical for the production of autocrine IL-3, thereby promoting the expression of IL-9","volume":"206","author":"Sabbaghi","year":"2021","journal-title":"J. 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Med."},{"key":"10.1016\/j.smim.2021.101510_bib0645","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.4049\/jimmunol.137.11.3521","article-title":"Astrocyte-derived interleukin 3 as a growth factor for microglia cells and peritoneal macrophages","volume":"137","author":"Frei","year":"1986","journal-title":"J. Immunol."},{"key":"10.1016\/j.smim.2021.101510_bib0650","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0165-5728(95)00057-9","article-title":"Expression of interleukin-3 and tumor necrosis factor-beta mRNAs in cultured microglia","volume":"60","author":"Appel","year":"1995","journal-title":"J. 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