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Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib68","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1126\/science.1164206","article-title":"Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity","volume":"322","author":"Hildner","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.smim.2026.102037_bib69","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.ccell.2017.04.003","article-title":"Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy","volume":"31","author":"Spranger","year":"2017","journal-title":"Cancer Cell."},{"key":"10.1016\/j.smim.2026.102037_bib70","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/s41590-020-00824-x","article-title":"The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens","volume":"22","author":"Canton","year":"2021","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib71","doi-asserted-by":"crossref","first-page":"4016","DOI":"10.1016\/j.cell.2021.05.021","article-title":"Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity","volume":"184","author":"Giampazolias","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.smim.2026.102037_bib72","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.immuni.2021.10.020","article-title":"Type I interferon activates MHC class I-dressed CD11b(+) conventional dendritic cells to promote protective anti-tumor CD8(+) T cell immunity","volume":"55","author":"Duong","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2026.102037_bib73","doi-asserted-by":"crossref","first-page":"5548","DOI":"10.1038\/sj.onc.1203957","article-title":"The protein tyrosine kinase family of the human genome","volume":"19","author":"Robinson","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.smim.2026.102037_bib74","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.cell.2007.11.013","article-title":"SnapShot: EGFR signaling pathway","volume":"131","author":"Yarden","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.smim.2026.102037_bib75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2017.03.003","article-title":"PDGFs and their receptors","volume":"614","author":"Kazlauskas","year":"2017","journal-title":"Gene"},{"key":"10.1016\/j.smim.2026.102037_bib76","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/nm0603-669","article-title":"The biology of VEGF and its receptors","volume":"9","author":"Ferrara","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.smim.2026.102037_bib77","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/s41586-021-04140-8","article-title":"Mechanism for the activation of the anaplastic lymphoma kinase receptor","volume":"600","author":"Reshetnyak","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.smim.2026.102037_bib78","doi-asserted-by":"crossref","first-page":"4074","DOI":"10.1038\/s41467-021-24367-3","article-title":"Structural basis of the activation of c-MET receptor","volume":"12","author":"Uchikawa","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.smim.2026.102037_bib79","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/s41588-021-00803-4","article-title":"Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice","volume":"53","author":"Wang","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.smim.2026.102037_bib80","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1158\/0008-5472.CAN-20-3351","article-title":"Activated ALK Cooperates with N-Myc via Wnt\/beta-Catenin Signaling to Induce Neuroendocrine Prostate Cancer","volume":"81","author":"Unno","year":"2021","journal-title":"Cancer Res."},{"key":"10.1016\/j.smim.2026.102037_bib81","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1186\/s12943-019-1073-4","article-title":"EGFR-TKI resistance promotes immune escape in lung cancer via increased PD-L1 expression","volume":"18","author":"Peng","year":"2019","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.smim.2026.102037_bib82","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s12943-018-0788-y","article-title":"Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products","volume":"17","author":"Siveen","year":"2018","journal-title":"Mol. 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Ther."},{"key":"10.1016\/j.smim.2026.102037_bib86","article-title":"Roles of non-receptor tyrosine kinases in pathogenesis and treatment of depression","volume":"21","author":"Mao","year":"2022","journal-title":"J. Integr. Neurosci."},{"key":"10.1016\/j.smim.2026.102037_bib87","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1038\/s41418-019-0321-x","article-title":"FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1\/2-dependent apoptosis","volume":"26","author":"Turunen","year":"2019","journal-title":"Cell. Death Differ."},{"key":"10.1016\/j.smim.2026.102037_bib88","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/nrc.2017.8","article-title":"Advances and challenges in targeting FGFR signalling in cancer","volume":"17","author":"Babina","year":"2017","journal-title":"Nat. Rev. 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J. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib104","doi-asserted-by":"crossref","first-page":"5635","DOI":"10.4049\/jimmunol.178.9.5635","article-title":"Macrophages and dendritic cells use different Axl\/Mertk\/Tyro3 receptors in clearance of apoptotic cells","volume":"178","author":"Seitz","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib105","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1172\/JCI72051","article-title":"An AXL\/LRP-1\/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo","volume":"124","author":"Subramanian","year":"2014","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.smim.2026.102037_bib106","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.bbrc.2023.09.021","article-title":"AXL receptor tyrosine kinase inhibition improves the anti-tumor effects of CD8(+) T cells by inducing CD103(+) dendritic cell-mediated T cell priming","volume":"680","author":"Im","year":"2023","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.smim.2026.102037_bib107","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.4049\/jimmunol.0804384","article-title":"Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl\/Gas6 pathway","volume":"183","author":"Scutera","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib108","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.canlet.2020.11.022","article-title":"Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy","volume":"499","author":"Llopiz","year":"2021","journal-title":"Cancer Lett."},{"key":"10.1016\/j.smim.2026.102037_bib109","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/s41590-024-02065-8","article-title":"Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer","volume":"26","author":"Belabed","year":"2025","journal-title":"Nat. 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Commun."},{"key":"10.1016\/j.smim.2026.102037_bib112","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtho.2022.07.608","article-title":"EP08.01-036 Low-dose EGFR-TKIs Directly Induce Maturation and Functional Activity of Human Dendritic Cells in an EGFR-independent manner","volume":"17","author":"Inoue","year":"2022","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.smim.2026.102037_bib113","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1038\/nm.4078","article-title":"The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death","volume":"22","author":"Pozzi","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.smim.2026.102037_bib114","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/jnci\/djad072","article-title":"Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer","volume":"115","author":"Li","year":"2023","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.smim.2026.102037_bib115","doi-asserted-by":"crossref","first-page":"5374","DOI":"10.1158\/0008-5472.CAN-16-2774","article-title":"Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells","volume":"77","author":"Gall","year":"2017","journal-title":"Cancer Res."},{"key":"10.1016\/j.smim.2026.102037_bib116","article-title":"Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk","volume":"5","author":"Wang","year":"2010","journal-title":"PLoS. One"},{"key":"10.1016\/j.smim.2026.102037_bib117","doi-asserted-by":"crossref","first-page":"4431","DOI":"10.1182\/blood-2003-02-0500","article-title":"Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin","volume":"102","author":"de Saint-Vis","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.smim.2026.102037_bib118","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2172-5-9","article-title":"Expression and functional effects of Eph receptor tyrosine kinase A family members on Langerhans like dendritic cells","volume":"5","author":"Munthe","year":"2004","journal-title":"BMC Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib119","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138835","article-title":"Expression of the Receptor Tyrosine Kinase EphB2 on Dendritic Cells Is Modulated by Toll-Like Receptor Ligation but Is Not Required for T Cell Activation","volume":"10","author":"Mimche","year":"2015","journal-title":"PLoS. One"},{"key":"10.1016\/j.smim.2026.102037_bib120","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216567","article-title":"EphB1 promotes the differentiation and maturation of dendritic cells in non-small cell lung cancer","volume":"582","author":"Xie","year":"2024","journal-title":"Cancer Lett."},{"key":"10.1016\/j.smim.2026.102037_bib121","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1356321","article-title":"Manipulating the tumor immune microenvironment to improve cancer immunotherapy: IGF1R, a promising target","volume":"15","author":"Pellegrino","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib122","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.canlet.2015.01.007","article-title":"Insulin-like growth factors inhibit dendritic cell-mediated anti-tumor immunity through regulating ERK1\/2 phosphorylation and p38 dephosphorylation","volume":"359","author":"Huang","year":"2015","journal-title":"Cancer Lett."},{"key":"10.1016\/j.smim.2026.102037_bib123","doi-asserted-by":"crossref","first-page":"E1016","DOI":"10.1073\/pnas.1520245113","article-title":"Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation","volume":"113","author":"Triplett","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.smim.2026.102037_bib124","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s12032-023-02023-8","article-title":"Identification of INSRR as an immune-related gene in the tumor microenvironment of glioblastoma by integrated bioinformatics analysis","volume":"40","author":"Zhang","year":"2023","journal-title":"Med. Oncol."},{"key":"10.1016\/j.smim.2026.102037_bib125","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.4049\/jimmunol.1200729","article-title":"The HGF receptor\/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity","volume":"189","author":"Baek","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib126","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/s41419-018-1010-2","article-title":"CCL19 suppresses angiogenesis through promoting miR-206 and inhibiting Met\/ERK\/Elk-1\/HIF-1alpha\/VEGF-A pathway in colorectal cancer","volume":"9","author":"Xu","year":"2018","journal-title":"Cell. Death Dis."},{"key":"10.1016\/j.smim.2026.102037_bib127","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1016\/j.jid.2022.12.025","article-title":"Met-Signaling Controls Dendritic Cell Migration in Skin by Regulating Podosome Formation and Function","volume":"143","author":"Hamouda","year":"2023","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.smim.2026.102037_bib128","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1002\/1521-4141(200207)32:7<1832::AID-IMMU1832>3.0.CO;2-2","article-title":"The impact of c-met\/scatter factor receptor on dendritic cell migration","volume":"32","author":"Kurz","year":"2002","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib129","doi-asserted-by":"crossref","first-page":"4745","DOI":"10.4049\/jimmunol.175.7.4745","article-title":"A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function","volume":"175","author":"Okunishi","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.smim.2026.102037_bib130","doi-asserted-by":"crossref","first-page":"688","DOI":"10.15537\/1658-3175.3889","article-title":"The role of hepatocyte growth factor in the differentiation of dendritic cells from peripheral blood monocytes","volume":"28","author":"Sonmez","year":"2007","journal-title":"Saudi Med. J."},{"key":"10.1016\/j.smim.2026.102037_bib131","article-title":"RON Expression Mediates Lipopolysaccharide-Mediated Dendritic Cell Maturation via March-I","volume":"10","author":"Huang","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.smim.2026.102037_bib132","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.4049\/jimmunol.175.3.1399","article-title":"The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion","volume":"175","author":"MacDonald","year":"2005","journal-title":"J. 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Res."},{"key":"10.1016\/j.smim.2026.102037_bib134","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/all.14011","article-title":"Colony-stimulating factor 1 and its receptor are new potential therapeutic targets for allergic asthma","volume":"75","author":"Moon","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.smim.2026.102037_bib135","doi-asserted-by":"crossref","first-page":"404","DOI":"10.4049\/jimmunol.174.1.404","article-title":"Enhancement of dendritic cell production by fms-like tyrosine kinase-3 ligand increases the resistance of mice to a burn wound infection","volume":"174","author":"Toliver-Kinsky","year":"2005","journal-title":"J. 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Biophys. Res. Commun."},{"key":"10.1016\/j.smim.2026.102037_bib152","doi-asserted-by":"crossref","first-page":"5279","DOI":"10.1038\/s41467-018-07685-x","article-title":"CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages","volume":"9","author":"Percin","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.smim.2026.102037_bib153","doi-asserted-by":"crossref","first-page":"981","DOI":"10.3389\/fimmu.2017.00981","article-title":"Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells","volume":"8","author":"Bandola","year":"2017","journal-title":"Front. 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Pathol."},{"key":"10.1016\/j.smim.2026.102037_bib159","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aag2611","article-title":"A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions","volume":"9","author":"Damelin","year":"2017","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.smim.2026.102037_bib160","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/cyto.b.22228","article-title":"PTK7 helps detect T lymphoblastic leukemia\/lymphoma by flow cytometry","volume":"108","author":"Maggard","year":"2025","journal-title":"Cytom. B Clin. Cytom."},{"key":"10.1016\/j.smim.2026.102037_bib161","doi-asserted-by":"crossref","first-page":"T105","DOI":"10.1530\/ERC-17-0303","article-title":"RET-mediated modulation of tumor microenvironment and immune response in multiple endocrine neoplasia type 2 (MEN2)","volume":"25","author":"Castellone","year":"2018","journal-title":"Endocr. Relat. 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Chem."},{"key":"10.1016\/j.smim.2026.102037_bib251","doi-asserted-by":"crossref","first-page":"2354","DOI":"10.1016\/j.immuni.2021.09.005","article-title":"Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity","volume":"54","author":"Sharma","year":"2021","journal-title":"Immunity"},{"key":"10.1016\/j.smim.2026.102037_bib252","article-title":"Bruton's tyrosine kinase and protein kinase C micro are required for TLR7\/9-induced IKKalpha and IRF-1 activation and interferon-beta production in conventional dendritic cells","volume":"9","author":"Li","year":"2014","journal-title":"PLoS. 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