{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T08:53:53Z","timestamp":1782118433828,"version":"3.54.5"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","soard.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery for Obesity and Related Diseases"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.soard.2015.04.022","type":"journal-article","created":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T21:16:59Z","timestamp":1430947019000},"page":"246-252","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["The influence of prophylactic proton pump inhibitor treatment on the development of symptomatic marginal ulceration in Roux-en-Y gastric bypass patients: a historic cohort study"],"prefix":"10.1016","volume":"12","author":[{"given":"Usha K.","family":"Coblijn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd M.","family":"Lagarde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve M.M.","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd D.","family":"Kuiken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem F.","family":"van Tets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart A.","family":"van Wagensveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.soard.2015.04.022_bib1","unstructured":"World Health Organisation [homepage on the Internet]. Geneva, Switzerland: WHO; 2015 Aug 1 [cited 2015 Jan 14]. Obesity and overweight. Available from: http:\/\/www\/who\/int\/mediacentre\/factsheets\/fs311\/en\/2014."},{"key":"10.1016\/j.soard.2015.04.022_bib2","first-page":"CD003641","article-title":"Surgery for weight loss in adults","volume":"8","author":"Colquitt","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"10.1016\/j.soard.2015.04.022_bib3","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s11695-012-0864-0","article-title":"Metabolic\/bariatric surgery worldwide 2011","volume":"23","author":"Buchwald","year":"2013","journal-title":"Obes Surg"},{"issue":"1","key":"10.1016\/j.soard.2015.04.022_bib4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1381\/096089296765557259","article-title":"Staple disruption and marginal ulceration in gastric bypass procedures for weight reduction","volume":"6","author":"Capella","year":"1996","journal-title":"Obes Surg"},{"issue":"7","key":"10.1016\/j.soard.2015.04.022_bib5","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1007\/s00464-007-9285-x","article-title":"Marginal ulceration after laparoscopic gastric bypass: an analysis of predisposing factors in 260 patients","volume":"21","author":"Rasmussen","year":"2007","journal-title":"Surg Endosc"},{"issue":"2","key":"10.1016\/j.soard.2015.04.022_bib6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s11695-008-9588-6","article-title":"Incidence of marginal ulcer 1 month and 1 to 2 years after gastric bypass: a prospective consecutive endoscopic evaluation of 442 patients with morbid obesity","volume":"19","author":"Csendes","year":"2009","journal-title":"Obes Surg"},{"issue":"9","key":"10.1016\/j.soard.2015.04.022_bib7","first-page":"1165","article-title":"Stomal complications of gastric bypass: incidence and outcome of therapy","volume":"87","author":"Sanyal","year":"1992","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1016\/j.soard.2015.04.022_bib8","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1381\/096089298765554061","article-title":"Marginal ulcer after gastric bypass: a prospective 3-year study of 173 patients","volume":"8","author":"Sapala","year":"1998","journal-title":"Obes Surg"},{"issue":"1","key":"10.1016\/j.soard.2015.04.022_bib9","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1381\/096089299765553674","article-title":"Gastro-gastric fistulas and marginal ulcers in gastric bypass procedures for weight reduction","volume":"9","author":"Capella","year":"1999","journal-title":"Obes Surg"},{"issue":"11","key":"10.1016\/j.soard.2015.04.022_bib10","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1007\/s11695-011-0470-6","article-title":"Comparison of hand-sewn, linear-stapled, and circular-stapled gastrojejunostomy in laparoscopic Roux-en-Y gastric bypass","volume":"21","author":"Bendewald","year":"2011","journal-title":"Obes Surg"},{"issue":"2","key":"10.1016\/j.soard.2015.04.022_bib11","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s11695-013-1118-5","article-title":"Development of ulcer disease after Roux-en-Y gastric bypass, incidence, risk factors, and patient presentation: a systematic review","volume":"24","author":"Coblijn","year":"2014","journal-title":"Obes Surg"},{"issue":"6","key":"10.1016\/j.soard.2015.04.022_bib12","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1381\/096089206777346754","article-title":"The influence of Helicobacter pylori infection on the development of gastric ulcer in symptomatic patients after bariatric surgery","volume":"16","author":"Yang","year":"2006","journal-title":"Obes Surg"},{"issue":"11","key":"10.1016\/j.soard.2015.04.022_bib13","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1007\/s00464-009-0449-8","article-title":"Preoperative bariatric screening and treatment of Helicobacter pylori","volume":"23","author":"Hartin","year":"2009","journal-title":"Surg Endosc"},{"issue":"11","key":"10.1016\/j.soard.2015.04.022_bib14","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1055\/s-0030-1256951","article-title":"Marginal ulceration after Roux-en-Y gastric bypass surgery: characteristics, risk factors, treatment, and outcomes","volume":"43","author":"Azagury","year":"2011","journal-title":"Endoscopy"},{"issue":"5","key":"10.1016\/j.soard.2015.04.022_bib15","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s11695-009-0062-x","article-title":"Can a short course of prophylactic low-dose proton pump inhibitor therapy prevent stomal ulceration after laparoscopic Roux-en-Y gastric bypass?","volume":"20","author":"D\u05f3Hondt","year":"2010","journal-title":"Obes Surg"},{"issue":"4","key":"10.1016\/j.soard.2015.04.022_bib16","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.soard.2006.12.008","article-title":"Risk of massive upper gastrointestinal bleeding in gastric bypass patients taking clopidogrel","volume":"3","author":"Caruana","year":"2007","journal-title":"Surg Obes Relat Dis"},{"issue":"4","key":"10.1016\/j.soard.2015.04.022_bib17","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.soard.2011.06.008","article-title":"Incidence of perforated gastrojejunal anastomotic ulcers after laparoscopic gastric bypass for morbid obesity and role of laparoscopy in their management","volume":"8","author":"Kalaiselvan","year":"2012","journal-title":"Surg Obes Relat Dis"},{"issue":"2","key":"10.1016\/j.soard.2015.04.022_bib18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1590\/S0004-28032010000200003","article-title":"Early marginal ulcer following Roux-en-Y gastric bypass under proton pump inhibitor treatment: prospective multicentric study","volume":"47","author":"Garrido","year":"2010","journal-title":"Arq Gastroenterol"},{"issue":"7","key":"10.1016\/j.soard.2015.04.022_bib19","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1007\/s00464-010-1553-5","article-title":"Wireless pH-metry at the gastrojejunostomy after Roux-en-Y gastric bypass: a novel use of the BRAVO system","volume":"25","author":"Hedberg","year":"2011","journal-title":"Surg Endosc"},{"issue":"1","key":"10.1016\/j.soard.2015.04.022_bib20","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11695-013-1079-8","article-title":"Interdisciplinary European guidelines on metabolic and bariatric surgery","volume":"24","author":"Fried","year":"2014","journal-title":"Obes Surg"},{"issue":"7","key":"10.1016\/j.soard.2015.04.022_bib21","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s00464-004-8132-6","article-title":"Optimal management of the morbidly obese patient. SAGES appropriateness conference statement","volume":"18","author":"Jones","year":"2004","journal-title":"Surg Endosc"},{"issue":"2","key":"10.1016\/j.soard.2015.04.022_bib22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.soard.2012.12.010","volume":"9","author":"Mechanick","year":"2013","journal-title":"Surg Obes Relat Dis"},{"issue":"5","key":"10.1016\/j.soard.2015.04.022_bib23","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s11695-014-1482-9","article-title":"Symptomatic marginal ulcer disease after Roux-en-Y gastric bypass: incidence, risk factors and management","volume":"25","author":"Coblijn","year":"2015","journal-title":"Obes Surg"},{"issue":"5","key":"10.1016\/j.soard.2015.04.022_bib24","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s11695-013-1152-3","article-title":"Management of anastomotic ulcers after Roux-en-Y gastric bypass: results of an international survey","volume":"24","author":"Steinemann","year":"2014","journal-title":"Obes Surg"},{"issue":"5","key":"10.1016\/j.soard.2015.04.022_bib25","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.soard.2012.06.012","article-title":"Effect of Helicobacter pylori on marginal ulcer and stomal stenosis after Roux-en-Y gastric bypass","volume":"9","author":"Rawlins","year":"2013","journal-title":"Surg Obes Relat Dis"},{"issue":"5","key":"10.1016\/j.soard.2015.04.022_bib26","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1007\/s00464-014-3794-1","article-title":"Prophylactic PPI help reduce marginal ulcers after gastric bypass surgery: a systematic review and meta-analysis of cohort studies","volume":"29","author":"Wu","year":"2015","journal-title":"Surg Endosc"},{"issue":"2","key":"10.1016\/j.soard.2015.04.022_bib27","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1007\/s00464-012-2492-0","article-title":"Omental patch repair effectively treats perforated marginal ulcer following Roux-en-Y gastric bypass","volume":"27","author":"Wendling","year":"2013","journal-title":"Surg Endosc"},{"issue":"1","key":"10.1016\/j.soard.2015.04.022_bib28","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1089\/lap.2010.0402","article-title":"Laparoscopic repair of perforated marginal ulcer following Roux-en-Y gastric bypass: a case series","volume":"21","author":"Wheeler","year":"2011","journal-title":"J Laparoendosc Adv Surg Tech A"},{"issue":"10","key":"10.1016\/j.soard.2015.04.022_bib29","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1007\/s00464-008-9996-7","article-title":"Perforated marginal ulcers after laparoscopic gastric bypass","volume":"22","author":"Felix","year":"2008","journal-title":"Surg Endosc"},{"issue":"6","key":"10.1016\/j.soard.2015.04.022_bib30","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.soard.2012.11.005","article-title":"Patient predictors of follow-up care attendance in Roux-en-Y gastric bypass patients","volume":"9","author":"McVay","year":"2013","journal-title":"Surg Obes Relat Dis"}],"container-title":["Surgery for Obesity and Related Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550728915001410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550728915001410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:02:03Z","timestamp":1761552123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550728915001410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["S1550728915001410"],"URL":"https:\/\/doi.org\/10.1016\/j.soard.2015.04.022","relation":{},"ISSN":["1550-7289"],"issn-type":[{"value":"1550-7289","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The influence of prophylactic proton pump inhibitor treatment on the development of symptomatic marginal ulceration in Roux-en-Y gastric bypass patients: a historic cohort study","name":"articletitle","label":"Article Title"},{"value":"Surgery for Obesity and Related Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.soard.2015.04.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}