{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:20:09Z","timestamp":1769077209191,"version":"3.49.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","soard.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery for Obesity and Related Diseases"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.soard.2017.12.017","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T03:38:20Z","timestamp":1514518700000},"page":"446-451","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effect of bariatric surgery on urinary sphingolipids in adolescents with severe obesity"],"prefix":"10.1016","volume":"14","author":[{"given":"Stephanie","family":"Davis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Nehus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Inge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wujuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Setchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Mitsnefes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.soard.2017.12.017_bib1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1001\/jama.2009.2012","article-title":"Prevalence of high body mass index in US children and adolescents, 2007-2008","volume":"303","author":"Ogden","year":"2010","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.soard.2017.12.017_bib2","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1001\/jama.2014.732","article-title":"Prevalence of childhood and adult obesity in the United States, 2011-2012","volume":"311","author":"Ogden","year":"2014","journal-title":"JAMA"},{"issue":"15","key":"10.1016\/j.soard.2017.12.017_bib3","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1161\/CIR.0b013e3182a5cfb3","article-title":"Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the American Heart Association","volume":"128","author":"Kelly","year":"2013","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.soard.2017.12.017_bib4","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3109\/17477161003587774","article-title":"Trends and racial\/ethnic disparities in severe obesity among US children and adolescents, 1976-2006","volume":"6","author":"Claire Wang","year":"2011","journal-title":"Int J Pediatr Obes"},{"issue":"1","key":"10.1016\/j.soard.2017.12.017_bib5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jpeds.2010.01.025","article-title":"Prevalence of extreme obesity in a multiethnic cohort of children and adolescents","volume":"157","author":"Koebnick","year":"2010","journal-title":"J Pediatr"},{"issue":"6","key":"10.1016\/j.soard.2017.12.017_bib6","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1038\/ki.1996.265","article-title":"The hyperfiltration theory: a paradigm shift in nephrology","volume":"49","author":"Brenner","year":"1996","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.soard.2017.12.017_bib7","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1046\/j.1523-1755.2001.0590041498.x","article-title":"Obesity-related glomerulopathy: an emerging epidemic","volume":"59","author":"Kambham","year":"2001","journal-title":"Kidney Int"},{"issue":"1","key":"10.1016\/j.soard.2017.12.017_bib8","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1053\/j.ajkd.2008.02.303","article-title":"Obesity-related glomerulopathy in China: a case series of 90 patients","volume":"52","author":"Chen","year":"2008","journal-title":"Am J Kidney Dis"},{"issue":"9","key":"10.1016\/j.soard.2017.12.017_bib9","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1093\/ndt\/16.9.1790","article-title":"Clinical features and long-term outcome of obesity-associated focal segmental glomerulosclerosis","volume":"16","author":"Praga","year":"2001","journal-title":"Nephrol Dial Transplant"},{"issue":"12","key":"10.1016\/j.soard.2017.12.017_bib10","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1681\/ASN.2010010085","article-title":"A multi-marker approach to predict incident CKD and microalbuminuria","volume":"21","author":"Fox","year":"2010","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.soard.2017.12.017_bib11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/sj.ki.5002586","article-title":"Association between obesity and kidney disease: a systematic review and meta-analysis","volume":"73","author":"Wang","year":"2008","journal-title":"Kidney Int"},{"issue":"8","key":"10.1016\/j.soard.2017.12.017_bib12","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/sj.ki.5002796","article-title":"Renal injury in the extremely obese patients with normal renal function","volume":"73","author":"Serra","year":"2008","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.soard.2017.12.017_bib13","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s00467-008-1024-6","article-title":"Obesity-related focal and segmental glomerulosclerosis: normalization of proteinuria in an adolescent after bariatric surgery","volume":"24","author":"Fowler","year":"2009","journal-title":"Pediatr Nephrol"},{"issue":"4","key":"10.1016\/j.soard.2017.12.017_bib14","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1067\/mpd.2001.113006","article-title":"Proteinuria and focal segmental glomerulosclerosis in severely obese adolescents","volume":"138","author":"Adelman","year":"2001","journal-title":"J Pediatr"},{"issue":"21","key":"10.1016\/j.soard.2017.12.017_bib15","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1001\/2013.jamainternmed.85","article-title":"Body mass index in 1.2 million adolescents and risk for end-stage renal disease","volume":"172","author":"Vivante","year":"2012","journal-title":"Arch Intern Med"},{"issue":"6","key":"10.1016\/j.soard.2017.12.017_bib16","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1542\/peds.2013-2185","article-title":"The effect of obesity in adolescence on adult health status","volume":"132","author":"Inge","year":"2013","journal-title":"Pediatrics"},{"key":"10.1016\/j.soard.2017.12.017_bib17","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3389\/fendo.2014.00127","article-title":"Podocyte pathology and nephropathy - sphingolipids in glomerular diseases","volume":"5","author":"Merscher","year":"2014","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"10","key":"10.1016\/j.soard.2017.12.017_bib18","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1194\/jlr.M500202-JLR200","article-title":"Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants","volume":"46","author":"Sun","year":"2005","journal-title":"J Lipid Res"},{"issue":"6","key":"10.1016\/j.soard.2017.12.017_bib19","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1111\/j.1523-1755.2005.00365.x","article-title":"Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)","volume":"67","author":"Levey","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.soard.2017.12.017_bib20","unstructured":"Ogden CL, Flegal KM. Changes in terminology for childhood overweight and obesity. Natl Health Stat Report 2010;(25):1\u20135."},{"issue":"29","key":"10.1016\/j.soard.2017.12.017_bib21","doi-asserted-by":"crossref","first-page":"25841","DOI":"10.1074\/jbc.R200011200","article-title":"Sphingolipid metabolism and signaling minireview series","volume":"277","author":"Smith","year":"2002","journal-title":"J Biol Chem"},{"issue":"29","key":"10.1016\/j.soard.2017.12.017_bib22","doi-asserted-by":"crossref","first-page":"25843","DOI":"10.1074\/jbc.R200009200","article-title":"De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway","volume":"277","author":"Merrill","year":"2002","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.soard.2017.12.017_bib23","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/nrm2329","article-title":"Principles of bioactive lipid signalling: lessons from sphingolipids","volume":"9","author":"Hannun","year":"2008","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"12","key":"10.1016\/j.soard.2017.12.017_bib24","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.bbamem.2006.08.009","article-title":"Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy","volume":"1758","author":"Zheng","year":"2006","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"10.1016\/j.soard.2017.12.017_bib25","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1124\/jpet.110.168815","article-title":"Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet","volume":"334","author":"Boini","year":"2010","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"10.1016\/j.soard.2017.12.017_bib26","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2337\/db08-1228","article-title":"Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance","volume":"58","author":"Haus","year":"2009","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.soard.2017.12.017_bib27","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1210\/er.2007-0025","article-title":"Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism","volume":"29","author":"Holland","year":"2008","journal-title":"Endocr Rev"},{"issue":"11","key":"10.1016\/j.soard.2017.12.017_bib28","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1038\/oby.2011.107","article-title":"Gastric bypass surgery reduces plasma ceramide subspecies and improves insulin sensitivity in severely obese patients","volume":"19","author":"Huang","year":"2011","journal-title":"Obesity (Silver Spring)"},{"issue":"6","key":"10.1016\/j.soard.2017.12.017_bib29","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1681\/ASN.2014050508","article-title":"Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis","volume":"26","author":"Nowling","year":"2015","journal-title":"J Am Soc Nephrol"},{"issue":"3","key":"10.1016\/j.soard.2017.12.017_bib30","doi-asserted-by":"crossref","first-page":"F204","DOI":"10.1152\/ajprenal.00150.2015","article-title":"Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells","volume":"309","author":"Subathra","year":"2015","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.soard.2017.12.017_bib31","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.cca.2016.10.005","article-title":"Biomarkers of morbid obesity and prediabetes by metabolomic profiling of human discordant phenotypes","volume":"463","author":"Tulipani","year":"2016","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.soard.2017.12.017_bib32","doi-asserted-by":"crossref","first-page":"e141","DOI":"10.1038\/nutd.2014.38","article-title":"Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults","volume":"4","author":"Hanamatsu","year":"2014","journal-title":"Nutr Diabetes"},{"issue":"12","key":"10.1016\/j.soard.2017.12.017_bib33","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1161\/01.ATV.20.12.2614","article-title":"Plasma sphingomyelin level as a risk factor for coronary artery disease","volume":"20","author":"Jiang","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.soard.2017.12.017_bib34","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1743-7075-3-5","article-title":"Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease","volume":"3","author":"Schlitt","year":"2006","journal-title":"Nutr Metabol"},{"key":"10.1016\/j.soard.2017.12.017_bib35","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ebiom.2016.03.033","article-title":"Mass spectrometry imaging reveals elevated glomerular ATP\/AMP in diabetes\/obesity and identifies sphingomyelin as a possible mediator","volume":"7","author":"Miyamoto","year":"2016","journal-title":"EBioMedicine"},{"issue":"3","key":"10.1016\/j.soard.2017.12.017_bib36","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1172\/JCI116299","article-title":"A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus","volume":"91","author":"Zador","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.soard.2017.12.017_bib37","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2369-13-70","article-title":"Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy","volume":"13","author":"Brunskill","year":"2012","journal-title":"BMC Nephrol"},{"issue":"2","key":"10.1016\/j.soard.2017.12.017_bib38","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.kint.2016.09.031","article-title":"Kidney outcomes 3 years after bariatric surgery in severely obese adolescents","volume":"91","author":"Nehus","year":"2016","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.soard.2017.12.017_bib39","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1002\/oby.21070","article-title":"Subclinical kidney injury before and 1 year after bariatric surgery among adolescents with severe obesity","volume":"23","author":"Xiao","year":"2015","journal-title":"Obesity (Silver Spring)"}],"container-title":["Surgery for Obesity and Related Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550728917311036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550728917311036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:07:41Z","timestamp":1761552461000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550728917311036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S1550728917311036"],"URL":"https:\/\/doi.org\/10.1016\/j.soard.2017.12.017","relation":{},"ISSN":["1550-7289"],"issn-type":[{"value":"1550-7289","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of bariatric surgery on urinary sphingolipids in adolescents with severe obesity","name":"articletitle","label":"Article Title"},{"value":"Surgery for Obesity and Related Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.soard.2017.12.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}