{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:24:44Z","timestamp":1787790284176,"version":"build-2784847793"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000779","name":"University of London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009148","name":"Queen Mary University of London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009148","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Social Science &amp; Medicine"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.socscimed.2026.119588","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T15:03:56Z","timestamp":1784214236000},"page":"119588","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["\u201cI want to be able to say that I did everything I could\u201d. Exploring the negotiations between the logic of care and the logic of research in clinical trials"],"prefix":"10.1016","volume":"405","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-4917","authenticated-orcid":false,"given":"Duncan J.","family":"Reynolds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8278-697X","authenticated-orcid":false,"given":"Manuela","family":"Perrotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7875-7562","authenticated-orcid":false,"given":"Giuliano","family":"Maeilli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.socscimed.2026.119588_bib1","series-title":"The Professional Guinea Pig: Big Pharma and the Risky World of Human Subjects","author":"Abadie","year":"2010"},{"key":"10.1016\/j.socscimed.2026.119588_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.imr.2019.01.001","article-title":"Should RCT's be used as the gold standard for evidence based medicine?","volume":"8","author":"Ahuja","year":"2019","journal-title":"Integr Med Res"},{"key":"10.1016\/j.socscimed.2026.119588_bib3","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1136\/adc.2004.058222","article-title":"Understanding randomised controlled trials","volume":"90","author":"Akobeng","year":"2005","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.socscimed.2026.119588_bib4","doi-asserted-by":"crossref","first-page":"20","DOI":"10.2307\/3562038","article-title":"False hopes and best data: consent to research and the therapeutic misconception","volume":"17","author":"Appelbaum","year":"1987","journal-title":"Hastings Cent. Rep."},{"key":"10.1016\/j.socscimed.2026.119588_bib5","series-title":"Randomized Control Trials in the Field of Development: a Critical Perspective","author":"B\u00e9d\u00e9carrats","year":"2020"},{"key":"10.1016\/j.socscimed.2026.119588_bib6","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"Braun","year":"2006","journal-title":"Qual. Res. Psychol."},{"key":"10.1016\/j.socscimed.2026.119588_bib7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1017\/S1745855207005029","article-title":"Are RCTs the Gold standard?","volume":"2","author":"Cartwright","year":"2007","journal-title":"BioSocieties"},{"key":"10.1016\/j.socscimed.2026.119588_bib8","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1177\/1077800413508523","article-title":"Scientific-based research and randomized controlled trials, the \u201cgold\u201d standard? Alternative paradigms and mixed methodologies","volume":"20","author":"Christ","year":"2014","journal-title":"Qual. Inq."},{"key":"10.1016\/j.socscimed.2026.119588_bib9","article-title":"Effectiveness and efficiency: Random reflections on health services","author":"Cochrane","year":"1972","journal-title":"Nuffield Trust"},{"key":"10.1016\/j.socscimed.2026.119588_bib10","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.socscimed.2017.12.005","article-title":"Understanding and misunderstanding randomized controlled trials","volume":"210","author":"Deaton","year":"2018","journal-title":"Soc. Sci. Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib11","series-title":"Chicago Guides to Writing, Editing, and Publishing","article-title":"Writing ethnographic fieldnotes","author":"Emerson","year":"2011"},{"key":"10.1016\/j.socscimed.2026.119588_bib12","series-title":"Transforming Clinical Research in the United States: Challenges and Opportunities: Workshop Summary","author":"English","year":"2010"},{"key":"10.1016\/j.socscimed.2026.119588_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12961-019-0462-x","article-title":"\u201cLike a nurse but not a nurse\u201d: Clinical research practitioners and the evolution of the clinical research delivery workforce in the NHS","volume":"17","author":"Faulkner-Gurstein","year":"2019","journal-title":"Health Res. Pol. Syst."},{"key":"10.1016\/j.socscimed.2026.119588_bib14","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0277-9536(01)00197-6","article-title":"\u201cWhy don't they just tell me straight, why allocate it?\u201d the struggle to make sense of participating in a randomised controlled trial","volume":"55","author":"Featherstone","year":"2002","journal-title":"Soc. Sci. Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib15","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1056\/NEJM198212233072604","article-title":"Double standards, scientific methods, and epidemiologic research","volume":"307","author":"Feinstein","year":"1982","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib16","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.3390\/ijerph16183232","article-title":"Integrating public health into climate change policy and planning: state of practice update","volume":"16","author":"Fox","year":"2019","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.socscimed.2026.119588_bib17","series-title":"Fundamentals of Clinical Trials","author":"Friedman","year":"2015"},{"key":"10.1016\/j.socscimed.2026.119588_bib18","doi-asserted-by":"crossref","DOI":"10.4155\/cli.14.116","article-title":"Data fraud in clinical trials","volume":"5","author":"George","year":"2015","journal-title":"Clin. Invest."},{"key":"10.1016\/j.socscimed.2026.119588_bib19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1080\/14740338.2023.2203488","article-title":"There is no single gold standard study design (RCTs are not the gold standard)","volume":"22","author":"Gerstman","year":"2023","journal-title":"Expert Opin. Drug Saf."},{"key":"10.1016\/j.socscimed.2026.119588_bib20","series-title":"Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients","author":"Goldacre","year":"2012"},{"key":"10.1016\/j.socscimed.2026.119588_bib21","series-title":"How to Read a Paper: the Basics of Evidence-based Medicine and Healthcare","author":"Greenhalgh","year":"2019"},{"key":"10.1016\/j.socscimed.2026.119588_bib22","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.g3725","article-title":"Evidence based medicine: a movement in crisis?","volume":"348","author":"Greenhalgh","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.socscimed.2026.119588_bib23","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1056\/NEJMp2409329","article-title":"The duffy null phenotype \u2014 addressing a source of discrimination in cancer care","volume":"391","author":"Hantel","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib24","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1111\/1471-0528.15199","article-title":"Randomised controlled trials\u2014the gold standard for effectiveness research","volume":"125","author":"Hariton","year":"2018","journal-title":"BJOG"},{"key":"10.1016\/j.socscimed.2026.119588_bib25","doi-asserted-by":"crossref","first-page":"28","DOI":"10.4212\/cjhp.v68i1.1422","article-title":"An introduction to the fundamentals of randomized controlled trials in pharmacy research","volume":"68","author":"Houle","year":"2015","journal-title":"Can. J. Hosp. Pharm."},{"key":"10.1016\/j.socscimed.2026.119588_bib26","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/1467-9566.12094","article-title":"Careful science? Bodywork and care practices in randomised clinical trials","volume":"36","author":"Jespersen","year":"2014","journal-title":"Sociol. Health Illness"},{"key":"10.1016\/j.socscimed.2026.119588_bib27","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/jep.13071","article-title":"Population ageing in a globalized world: risks and dilemmas?","volume":"25","author":"Khan","year":"2019","journal-title":"J. Eval. Clin. Pract."},{"key":"10.1016\/j.socscimed.2026.119588_bib28","series-title":"The Logic of Care: Health and the Problem of Patient Choice","author":"Mol","year":"2008"},{"key":"10.1016\/j.socscimed.2026.119588_bib29","series-title":"Medical Proofs, Social Experiments: Clinical Trials in Shifting Contexts","author":"Moreira","year":"2012"},{"key":"10.1016\/j.socscimed.2026.119588_bib30","series-title":"The SAGE Encyclopedia of Communication Research Methods","first-page":"455","article-title":"Ethnographic interview","author":"Munz","year":"2018"},{"key":"10.1016\/j.socscimed.2026.119588_bib31","first-page":"387","article-title":"The ethics of clinical trials","volume":"8","author":"Nardini","year":"2014","journal-title":"Ecancermedicalscience"},{"key":"10.1016\/j.socscimed.2026.119588_bib32","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.socscimed.2014.04.008","article-title":"Testing devices or experimental systems? Cancer clinical trials take the genomic turn","volume":"111","author":"Nelson","year":"2014","journal-title":"Soc. Sci. Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib33","doi-asserted-by":"crossref","first-page":"53","DOI":"10.21586\/ross0000004","article-title":"Handling the Hawthorne effect: the challenges surrounding a participant observer","volume":"1","author":"Oswald","year":"2014","journal-title":"Rev. Soc. Stud."},{"key":"10.1016\/j.socscimed.2026.119588_bib34","series-title":"When Experiments Travel: Clinical Trials and the Global Search for Human Subjects","author":"Petryna","year":"2009"},{"key":"10.1016\/j.socscimed.2026.119588_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.socscimed.2020.112961","article-title":"A mixed-methods systematic review of patients' experience of being invited to participate in surgical randomised controlled trials","volume":"253","author":"Phelps","year":"2020","journal-title":"Soc. Sci. Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib36","series-title":"Clinical Trials: a Methodologic Perspective","author":"Piantadosi","year":"2024"},{"key":"10.1016\/j.socscimed.2026.119588_bib37","series-title":"A Practice-based Approach to Trust: an Ethnographic Study on Trusting in Medical Practices (Phd)","author":"Reynolds","year":"2023"},{"key":"10.1016\/j.socscimed.2026.119588_bib38","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1186\/s13063-025-08993-6","article-title":"Finding trials for participants: an ethnographic study of successful recruitment strategies for clinical trials","volume":"26","author":"Reynolds","year":"2025","journal-title":"Trials"},{"key":"10.1016\/j.socscimed.2026.119588_bib39","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.312.7023.71","article-title":"Evidence based medicine: what it is and what it isn't","volume":"312","author":"Sackett","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.socscimed.2026.119588_bib40","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2022-074256","article-title":"Practical thematic analysis: a guide for multidisciplinary health services research teams engaging in qualitative analysis","volume":"381","author":"Saunders","year":"2023","journal-title":"BMJ"},{"key":"10.1016\/j.socscimed.2026.119588_bib41","series-title":"Making Medical Knowledge","author":"Solomon","year":"2015"},{"key":"10.1016\/j.socscimed.2026.119588_bib42","series-title":"Medical Proofs, Social Experiments","article-title":"Reconciling research with medical care in RCTs","author":"Timmermans","year":"2010"},{"key":"10.1016\/j.socscimed.2026.119588_bib43","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1177\/0162243910366155","article-title":"The joy of science: finding success in a \u201cfailed\u201d randomized clinical trial","volume":"36","author":"Timmermans","year":"2011","journal-title":"Sci. Technol. Hum. Val."},{"key":"10.1016\/j.socscimed.2026.119588_bib44","series-title":"The Gold Standard: the Challenge of Evidence-based Medicine and Standardization in Health Care","author":"Timmermans","year":"2003"},{"key":"10.1016\/j.socscimed.2026.119588_bib45","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1164\/rccm.202201-0136SO","article-title":"Fiftieth anniversary of uncovering the tuskegee syphilis study: the story and timeless lessons","volume":"205","author":"Tobin","year":"2022","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.socscimed.2026.119588_bib46","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1542\/hpeds.2022-006690","article-title":"Hierarchy of evidence within the medical literature","volume":"12","author":"Wallace","year":"2022","journal-title":"Hosp. Pediatr."},{"key":"10.1016\/j.socscimed.2026.119588_bib47","series-title":"Ethnography in Higher Education","author":"Wieser","year":"2020"},{"key":"10.1016\/j.socscimed.2026.119588_bib48","author":"Will"},{"key":"10.1016\/j.socscimed.2026.119588_bib49","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1017\/S1745855207005078","article-title":"The alchemy of clinical trials","volume":"2","author":"Will","year":"2007","journal-title":"BioSocieties"},{"key":"10.1016\/j.socscimed.2026.119588_bib50","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1177\/0162243909340261","article-title":"Identifying effectiveness in \u2018\u201cThe old old\u201d\u2019: principles and values in the age of clinical trials","volume":"34","author":"Will","year":"2009","journal-title":"Sci. Technol. Hum. Val."},{"key":"10.1016\/j.socscimed.2026.119588_bib51","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3102\/00346543047002245","article-title":"The use of ethnographic techniques in educational research","volume":"47","author":"Wilson","year":"1977","journal-title":"Rev. Educ. Res."}],"container-title":["Social Science &amp; Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0277953626006647?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0277953626006647?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:08:36Z","timestamp":1787789316000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0277953626006647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":51,"alternative-id":["S0277953626006647"],"URL":"https:\/\/doi.org\/10.1016\/j.socscimed.2026.119588","relation":{},"ISSN":["0277-9536"],"issn-type":[{"value":"0277-9536","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u201cI want to be able to say that I did everything I could\u201d. Exploring the negotiations between the logic of care and the logic of research in clinical trials","name":"articletitle","label":"Article Title"},{"value":"Social Science & Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.socscimed.2026.119588","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"119588"}}