{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:37:44Z","timestamp":1790879864229,"version":"4.1.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Oncology Nursing"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1016\/j.soncn.2006.04.004","type":"journal-article","created":{"date-parts":[[2006,8,8]],"date-time":"2006-08-08T12:46:58Z","timestamp":1155041218000},"page":"163-173","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":139,"title":["Evidence-Based Skin Care Management in Radiation Therapy"],"prefix":"10.1016","volume":"22","author":[{"given":"Maurene","family":"McQuestion","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.soncn.2006.04.004_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0885-3924(91)90015-V","article-title":"Skin problems in advanced and terminal cancer patients","volume":"6","author":"De Conno","year":"1991","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.soncn.2006.04.004_bib2","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.12968\/bjon.1999.8.17.6503","article-title":"Radiation-induced reactions. 1: An examination of the phenomenon","volume":"8","author":"Noble-Adams","year":"1999","journal-title":"Br J Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib3","first-page":"193","article-title":"Impaired skin integrity related to radiation therapy","volume":"17","author":"Ratliff","year":"1990","journal-title":"J Enterostom Ther"},{"key":"10.1016\/j.soncn.2006.04.004_bib4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0167-8140(02)00060-9","article-title":"The radiotherapeutic injury \u2013 A complex \u2018wound\u2019","volume":"63","author":"Denham","year":"2002","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib5","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/00129334-200209000-00007","article-title":"Wound care after radiation therapy","volume":"15","author":"Mendelsohn","year":"2002","journal-title":"Adv Skin Wound Care"},{"key":"10.1016\/j.soncn.2006.04.004_bib6","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0194-5998(99)70062-8","article-title":"Choosing the optimal wound dressing for irradiated soft tissue wounds","volume":"121","author":"Hom","year":"1999","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.soncn.2006.04.004_bib7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/193293a0","article-title":"Formation of the scab and the rate of epithelialization of superficial wounds in the skin of the young domestic pig","volume":"193","author":"Winter","year":"1962","journal-title":"Nature"},{"key":"10.1016\/j.soncn.2006.04.004_bib8","first-page":"40","article-title":"Maintaining skin integrity during radiation therapy","volume":"97","author":"Korinko","year":"1997","journal-title":"Am J Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib9","first-page":"33","article-title":"Factors influencing the severity of radiation skin and oral mucosal reactions","volume":"11","author":"Porock","year":"2002","journal-title":"Eur J Cancer Care"},{"key":"10.1016\/j.soncn.2006.04.004_bib10","first-page":"907","article-title":"Early and late radiation-induced skin alterations. Part II: Nursing care of irradiated skin","author":"Sitton","year":"1992","journal-title":"Oncol Nurs Forum"},{"key":"10.1016\/j.soncn.2006.04.004_bib11","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/S0360-3016(02)02756-6","article-title":"Skin toxicity due to intensity-modulated radiotherapy for head-and-neck cancer","volume":"53","author":"Lee","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.soncn.2006.04.004_bib12","first-page":"3","article-title":"Skin care recommendations during radiotherapy","volume":"34","author":"Bolderston","year":"2003","journal-title":"Can J MRT"},{"key":"10.1016\/j.soncn.2006.04.004_bib13","unstructured":"Bolderston A, Lloyd NS, Wong RKS, et al and Members of the Supportive Care Guidelines Group. Program in evidence-based care. A Cancer Care Ontario program. Available at www.cancercare.on.ca (accessed May 11, 2006)."},{"key":"10.1016\/j.soncn.2006.04.004_bib14","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1188\/05.ONF.1199-1205","article-title":"The standardization of radiation skin care in British Columbia","volume":"32","author":"Nystedt","year":"2005","journal-title":"Oncol Nurs Forum"},{"key":"10.1016\/j.soncn.2006.04.004_bib15","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0936-6555(05)80971-9","article-title":"Can patients wash during radiotherapy to the breast or chest wall? A randomized controlled trial","volume":"4","author":"Campbell","year":"1992","journal-title":"Clin Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib16","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0167-8140(00)00322-4","article-title":"The impact of skin washing with water and soap during breast irradiation","volume":"58","author":"Roy","year":"2001","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib17","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0190-9622(79)70001-6","article-title":"The soap chamber","volume":"1","author":"Frosch","year":"1979","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.soncn.2006.04.004_bib18","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0167-8140(99)00146-2","article-title":"Advice on hair and scalp care during cranial radiotherapy","volume":"54","author":"Westbury","year":"2000","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib19","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0360-3016(97)00095-3","article-title":"Measurement of 6-MV X-ray surface dose when topical agents are applied prior to external beam irradiation","volume":"38","author":"Burch","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.soncn.2006.04.004_bib20","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/00002820-200212000-00007","article-title":"A phase II study on the efficacy of topical aloe vera gel on irradiated breast tissue","volume":"25","author":"Heggie","year":"2002","journal-title":"Cancer Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib21","first-page":"543","article-title":"The effect of aloe vera gel\/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy","volume":"3","author":"Olsen","year":"2001","journal-title":"Oncol Nurs Forum"},{"key":"10.1016\/j.soncn.2006.04.004_bib22","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0360-3016(96)00320-3","article-title":"Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity","volume":"36","author":"Williams","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.soncn.2006.04.004_bib23","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1017\/S146039699900031X","article-title":"Pilot study to investigate the toxicity of aloe Vera gel in the management of radiation induced skin reactions for post-operative primary breast cancer","volume":"1","author":"Dudek","year":"2000","journal-title":"J Radiother Pract"},{"key":"10.1016\/j.soncn.2006.04.004_bib24","first-page":"823","article-title":"Aloe vera","volume":"49","author":"Vogler","year":"1999","journal-title":"Br J General Pract"},{"key":"10.1016\/j.soncn.2006.04.004_bib25","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/S0360-3016(00)00782-3","article-title":"Randomized phase III study comparing best supportive care to Biafine as a prophylactic agent for radiation-induced skin toxicity for women undergoing breast irradiation","volume":"48","author":"Fisher","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.soncn.2006.04.004_bib26","first-page":"305","article-title":"Topical Biafine and Liperderm for the prevention of radiation dermatitis","volume":"8","author":"Fenig","year":"2001","journal-title":"Oncol Rep"},{"key":"10.1016\/j.soncn.2006.04.004_bib27","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1200\/JCO.2004.07.063","article-title":"Phase III randomized trial of Calendual Officinalis compared with Tromaline for the prevention of acute dermatitis during irradiation for breast cancer","volume":"22","author":"Pommier","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib28","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0167-8140(96)01882-8","article-title":"Double-blind randomized clinical trial comparing hyaluronic acid cream to placebo in patients treated with radiotherapy","volume":"42","author":"Liguori","year":"1997","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib29","first-page":"333","article-title":"Hyaluronic acid prevents oxygen free-radical damage to granulation tissue","volume":"12","author":"Foschi","year":"1990","journal-title":"Int J Tissue Reactions"},{"key":"10.1016\/j.soncn.2006.04.004_bib30","first-page":"34","article-title":"Topical corticosteroids","volume":"Vol 11","author":"Yohn","year":"1990"},{"key":"10.1016\/j.soncn.2006.04.004_bib31","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0167-8140(01)00327-9","article-title":"Potent corticosteroid cream (mometasone furoate) significantly reduces acute radiation dermatitis","volume":"59","author":"Bostrom","year":"2001","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib32","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1046\/j.1365-2133.2002.04751.x","article-title":"Topical corticosteroid therapy for acute radiation dermatitis","volume":"146","author":"Schmuth","year":"2002","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.soncn.2006.04.004_bib33","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0009-9260(79)80217-2","article-title":"Effectiveness of topical steroids in the control of radiation dermatitis","volume":"30","author":"Glees","year":"1979","journal-title":"Clin Radiol"},{"key":"10.1016\/j.soncn.2006.04.004_bib34","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1148\/radiology.143.3.7079509","article-title":"Prophylaxis of radiation dermatitis with a topical cortisone cream","volume":"143","author":"Potera","year":"1982","journal-title":"Radiology"},{"key":"10.1016\/j.soncn.2006.04.004_bib35","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/0002-9343(89)90154-X","article-title":"Epidermal growth factor in the gastroprotective and ulcer healing action of sucralfate in rats","volume":"86","author":"Konturek","year":"1989","journal-title":"Am J Med"},{"key":"10.1016\/j.soncn.2006.04.004_bib36","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/BF01536921","article-title":"Effect of sucralfate and its components on taurocholate-induced damage to rate gastric mucosal cells in tissue culture","volume":"35","author":"Romano","year":"1990","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.soncn.2006.04.004_bib37","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1080\/02841860152619188","article-title":"Effects of Na-sucrose octasulfate on skin and mucosa reactions during radiotherapy of head and neck cancers","volume":"40","author":"Evensen","year":"2001","journal-title":"Acta Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib38","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3109\/02841869409098406","article-title":"Skin protection by sucralfate cream during electron beam therapy","volume":"33","author":"Maiche","year":"1994","journal-title":"Acta Oncologica"},{"key":"10.1016\/j.soncn.2006.04.004_bib39","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.radonc.2004.07.032","article-title":"Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions? A randomised controlled trial","volume":"73","author":"Wells","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib40","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.ijrobp.2004.04.033","article-title":"Effect of oral sucralfate on late rectal injury associated with radiotherapy for prostate cancer","volume":"60","author":"Kneebone","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.soncn.2006.04.004_bib41","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0167-8140(97)00231-4","article-title":"Does sucralfate reduce the acute side-effects in head and neck cancer treated with radiotherapy? A double-blind randomized trial","volume":"47","author":"Lievens","year":"1998","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib42","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/j.1440-1673.1997.tb00672.x","article-title":"Sucralfate cream in the management of moist desquamation during radiotherapy","volume":"41","author":"Delaney","year":"1997","journal-title":"Australas Radiol"},{"key":"10.1016\/j.soncn.2006.04.004_bib43","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0360-3016(03)01431-7","article-title":"Randomized paired comparison of No-Sting barrier film versus sorbolene cream (10% glycerine) skin care during postmastectomy irradiation","volume":"58","author":"Graham","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.soncn.2006.04.004_bib44","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0936-6555(98)80064-2","article-title":"A pilot study of Dermofilm in acute radiation-induced desquamative skin reactions","volume":"10","author":"See","year":"1998","journal-title":"Clin Oncol"},{"key":"10.1016\/j.soncn.2006.04.004_bib45","first-page":"620","article-title":"Topical antibacterial agents for wound care","volume":"29","author":"Thornton Spann","year":"2003","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.soncn.2006.04.004_bib46","first-page":"11","article-title":"Comparison of moisture vapor permeable (MVP) dressings to conventional dressings for the management of radiation skin reactions","author":"Shell","year":"1986","journal-title":"Oncol Nurs Forum"},{"key":"10.1016\/j.soncn.2006.04.004_bib47","first-page":"71","article-title":"Management of radiation-induced moist skin desquamation using hydrocolloid dressing","volume":"13","author":"Margolin","year":"1990","journal-title":"Cancer Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib48","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/00002820-200006000-00010","article-title":"The effects of hydrocolloid dressing and gentian violet on radiation induced moist desquamation wound healing","volume":"23","author":"Mak","year":"2000","journal-title":"Cancer Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib49","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.12968\/bjon.2003.12.Sup4.12215","article-title":"An overview of Acticoat dressing in wound management","volume":"12","author":"Dowsett","year":"2003","journal-title":"Br J Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib50","first-page":"41","article-title":"A guide to the properties and uses of silver dressings in wound care","volume":"20","author":"Lansdown","year":"2005","journal-title":"Prof Nurs"},{"key":"10.1016\/j.soncn.2006.04.004_bib51","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ijrobp.2003.11.031","article-title":"Silver leaf nylon dressing to prevent radiation dermatitis in patients undergoing chemotherapy and external beam radiotherapy to the perineum","volume":"59","author":"Vuong","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Seminars in Oncology Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749208106000581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749208106000581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T04:35:49Z","timestamp":1760070949000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749208106000581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S0749208106000581"],"URL":"https:\/\/doi.org\/10.1016\/j.soncn.2006.04.004","relation":{},"ISSN":["0749-2081"],"issn-type":[{"value":"0749-2081","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evidence-Based Skin Care Management in Radiation Therapy","name":"articletitle","label":"Article Title"},{"value":"Seminars in Oncology Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.soncn.2006.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}