{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:00:54Z","timestamp":1790805654364,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100021016","name":"Istituto di Ricovero e Cura a Carattere Scientifico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100021016","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Oncology Nursing"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.soncn.2026.152396","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T06:22:57Z","timestamp":1790576577000},"page":"152396","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Effects of Microbiota-Modifying Interventions for Gastrointestinal Disorders in Adults with Colorectal Cancer: A Systematic Review and Network Meta-Analysis"],"prefix":"10.1016","volume":"42","author":[{"given":"Silvia","family":"Belloni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Magon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"La Bella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Giacon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Alfredo","family":"Arcidiacono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Conte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7736-6209","authenticated-orcid":false,"given":"Rosario","family":"Caruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Arrigoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0001","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"4","key":"10.1016\/j.soncn.2026.152396_bib0002","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1136\/gutjnl-2015-310912","article-title":"Global patterns and trends in colorectal cancer incidence and mortality","volume":"66","author":"Arnold","year":"2017","journal-title":"Gut"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0003","doi-asserted-by":"crossref","first-page":"E132","DOI":"10.1097\/NCC.0000000000000785","article-title":"Symptom experiences in colorectal cancer survivors after cancer treatments: a systematic review and meta-analysis","volume":"43","author":"Han","year":"2020","journal-title":"Cancer Nurs"},{"issue":"14","key":"10.1016\/j.soncn.2026.152396_bib0004","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.3390\/cancers16142597","article-title":"Chemotoxicity and associated risk factors in colorectal cancer: a systematic review and meta-analysis","volume":"16","author":"Han","year":"2024","journal-title":"Cancers"},{"issue":"11","key":"10.1016\/j.soncn.2026.152396_bib0005","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S1470-2045(07)70341-8","article-title":"Gastrointestinal symptoms after pelvic radiotherapy: a new understanding to improve management of symptomatic patients","volume":"8","author":"Andreyev","year":"2007","journal-title":"Lancet Oncol"},{"issue":"8","key":"10.1016\/j.soncn.2026.152396_bib0006","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/nrgastro.2017.75","article-title":"Expert consensus document: the International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics","volume":"14","author":"Gibson","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0007","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3390\/nu14020356","article-title":"When eating becomes torturous: understanding nutrition-related cancer treatment side effects among individuals with cancer and their caregivers","volume":"14","author":"Milliron","year":"2022","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0008","doi-asserted-by":"crossref","first-page":"pkaf048","DOI":"10.1093\/jncics\/pkaf048","article-title":"Thriving after cancer: a special collection on the benefits of exercise and nutrition in cancer survivorship","volume":"9","author":"Tchelebi","year":"2025","journal-title":"JNCI Cancer Spectr"},{"issue":"6","key":"10.1016\/j.soncn.2026.152396_bib0009","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nrgastro.2017.20","article-title":"Gut microbiota modulation of chemotherapy efficacy and toxicity","volume":"14","author":"Alexander","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0010","doi-asserted-by":"crossref","first-page":"648","DOI":"10.7150\/jca.99421","article-title":"Important role of intestinal microbiota in chemotherapy-induced diarrhea and therapeutics","volume":"16","author":"Jiang","year":"2025","journal-title":"J Cancer"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0011","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3390\/antibiotics14030264","article-title":"Exploring the impact of chemotherapy on the emergence of antibiotic resistance in the gut microbiota of colorectal cancer patients","volume":"14","author":"Kenneth","year":"2025","journal-title":"Antibiotics"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0012","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/SPC.0000000000000704","article-title":"The systemic outcomes of gastrointestinal mucositis: host-microbe interaction leading to systemic inflammatory responses","volume":"18","author":"Stringer","year":"2024","journal-title":"Curr Opin Support Palliat Care"},{"issue":"1","key":"10.1016\/j.soncn.2026.152396_bib0013","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s13073-016-0306-z","article-title":"Microbiome mediation of infections in the cancer setting","volume":"8","author":"Taur","year":"2016","journal-title":"Genome Med"},{"issue":"5","key":"10.1016\/j.soncn.2026.152396_bib0014","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/nrc.2017.13","article-title":"Microbiota: a key orchestrator of cancer therapy","volume":"17","author":"Roy","year":"2017","journal-title":"Nat Rev Cancer"},{"issue":"6529","key":"10.1016\/j.soncn.2026.152396_bib0015","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1126\/science.abb5920","article-title":"Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients","volume":"371","author":"Baruch","year":"2021","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.soncn.2026.152396_bib0016","doi-asserted-by":"crossref","first-page":"6022","DOI":"10.3390\/ijms25116022","article-title":"Effects of probiotics on gut microbiota: an overview","volume":"25","author":"Chandrasekaran","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.soncn.2026.152396_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2025.118559","article-title":"Bacteria-mediated cancer therapy (BMCT): therapeutic applications, clinical insights, and the microbiome as an emerging hallmark of cancer","volume":"192","author":"Jayaprakash","year":"2025","journal-title":"Biomed Pharmacother"},{"issue":"4","key":"10.1016\/j.soncn.2026.152396_bib0018","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1038\/s41564-026-02279-6","article-title":"A clinic-responder-derived defined microbial consortium enhances anti-PD-1 immunotherapy efficacy in mice","volume":"11","author":"Zhou","year":"2026","journal-title":"Nat Microbiol"},{"issue":"5","key":"10.1016\/j.soncn.2026.152396_bib0019","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.colegn.2023.08.001","article-title":"Factors associated with nursing practice for cancer patients using complementary and alternative medicine","volume":"30","author":"Kusunoki","year":"2023","journal-title":"Collegian"},{"key":"10.1016\/j.soncn.2026.152396_bib0020","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.823288","article-title":"Oral administration of probiotics reduces chemotherapy-induced diarrhea and oral mucositis: a systematic review and meta-analysis","volume":"9","author":"Feng","year":"2022","journal-title":"Front Nutr"},{"key":"10.1016\/j.soncn.2026.152396_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctim.2025.103151","article-title":"Oral probiotic supplementation to alleviate diarrhea induced by fluoropyrimidines or irinotecan-based chemotherapy: a systematic review and meta-analysis","volume":"89","author":"Siritientong","year":"2025","journal-title":"Complement Ther Med"},{"issue":"27","key":"10.1016\/j.soncn.2026.152396_bib0022","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000043126","article-title":"Efficacy and safety of probiotics in preventing chemotherapy-related diarrhea in patients with colorectal cancer: a systematic review and meta-analysis based on 18 randomized trials","volume":"104","author":"Yang","year":"2025","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"10.1016\/j.soncn.2026.152396_bib0023","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/s12876-025-03914-y","article-title":"Evaluation of the efficacy of probiotics in the chemoradiotherapy of colorectal cancer: a meta-analysis of randomized controlled trials","volume":"25","author":"Yang","year":"2025","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.soncn.2026.152396_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2025.104779","article-title":"Symptomatologic outcomes of gut microbiota modifiers (probiotics, prebiotics and synbiotics) in cancer care: a scoping review of randomized controlled trials","volume":"212","author":"Belloni","year":"2025","journal-title":"Crit Rev Oncol Hematol"},{"issue":"11","key":"10.1016\/j.soncn.2026.152396_bib0025","doi-asserted-by":"crossref","first-page":"777","DOI":"10.7326\/M14-2385","article-title":"The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations","volume":"162","author":"Hutton","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.soncn.2026.152396_bib0026","unstructured":"Higgins J, Thomas J, Chandler J. Cochrane handbook for systematic reviews of interventions version 6.5 (updated August 2024). Cochrane; 2024. https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook\/current"},{"issue":"9","key":"10.1016\/j.soncn.2026.152396_bib0027","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138237","article-title":"The role of google scholar in evidence reviews and its applicability to grey literature searching","volume":"10","author":"Haddaway","year":"2015","journal-title":"PLOS ONE"},{"key":"10.1016\/j.soncn.2026.152396_bib0028","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.soncn.2026.152396_bib0029","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2024-079839","article-title":"Risk of bias in network meta-analysis (RoB NMA) tool","volume":"388","author":"Lunny","year":"2025","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.soncn.2026.152396_bib0030","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/jrsm.1316","article-title":"A comparison of heterogeneity variance estimators in simulated random-effects meta-analyses","volume":"10","author":"Langan","year":"2019","journal-title":"Res Synth Methods"},{"issue":"11","key":"10.1016\/j.soncn.2026.152396_bib0031","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0032","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ctim.2015.03.008","article-title":"Prevention of irinotecan induced diarrhea by probiotics: a randomized double blind, placebo controlled pilot study","volume":"23","author":"Mego","year":"2015","journal-title":"Complement Ther Med"},{"key":"10.1016\/j.soncn.2026.152396_bib0033","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1168654","article-title":"Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12\u00aeLactobacillus rhamnosus LGG\u00ae in colorectal cancer patients","volume":"13","author":"Mego","year":"2023","journal-title":"Front Oncol"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0034","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/jrsm.1044","article-title":"Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies","volume":"3","author":"Higgins","year":"2012","journal-title":"Res Synth Methods"},{"issue":"474","key":"10.1016\/j.soncn.2026.152396_bib0035","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1198\/016214505000001302","article-title":"Assessing evidence inconsistency in mixed treatment comparisons","volume":"101","author":"Lu","year":"2006","journal-title":"J Am Stat Assoc"},{"issue":"10","key":"10.1016\/j.soncn.2026.152396_bib0036","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076654","article-title":"Graphical tools for network meta-analysis in STATA","volume":"8","author":"Chaimani","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.soncn.2026.152396_bib0037","article-title":"CINeMA: software for semiautomated assessment of the confidence in the results of network meta-analysis","volume":"16","author":"Papakonstantinou","year":"2020","journal-title":"Campbell Syst Rev"},{"issue":"8","key":"10.1016\/j.soncn.2026.152396_bib0038","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/sj.bjc.6603990","article-title":"Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study","volume":"97","author":"Osterlund","year":"2007","journal-title":"Br J Cancer"},{"issue":"6","key":"10.1016\/j.soncn.2026.152396_bib0039","doi-asserted-by":"crossref","first-page":"E335","DOI":"10.1188\/09.ONF.E335-E342","article-title":"Effect of kefir on the quality of life of patients being treated for colorectal cancer","volume":"36","author":"Can","year":"2009","journal-title":"Oncol Nurs Forum"},{"issue":"6","key":"10.1016\/j.soncn.2026.152396_bib0040","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s10637-008-9171-y","article-title":"Effect of oral administration of kefir on serum proinflammatory cytokines on 5-FU induced oral mucositis in patients with colorectal cancer","volume":"26","author":"Topuz","year":"2008","journal-title":"Invest New Drugs"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0041","article-title":"A clinical trial on preventive efficacy on CPT11induced diarrhea by Bifidobacterium capsules","volume":"23","author":"ping","year":"2011","journal-title":"Chin J Microecol"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0042","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/ajco.12758","article-title":"Strain-specific probiotic (microbial cell preparation) and omega-3 fatty acid in modulating quality of life and inflammatory markers in colorectal cancer patients: a randomized controlled trial","volume":"14","author":"Golkhalkhali","year":"2018","journal-title":"Asia Pac J Clin Oncol"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0043","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3390\/nu15020356","article-title":"Postoperative probiotics administration attenuates gastrointestinal complications and gut microbiota dysbiosis caused by chemotherapy in colorectal cancer patients","volume":"15","author":"Huang","year":"2023","journal-title":"Nutrients"},{"issue":"10","key":"10.1016\/j.soncn.2026.152396_bib0044","first-page":"799","article-title":"A randomized controlled clinical study on the effect of synbiotics on improving the adverse reactions of chemotherapy in patients with colorectal cancer","volume":"31","author":"Lu","year":"2019","journal-title":"Shanghai J Prev Med"},{"issue":"32","key":"10.1016\/j.soncn.2026.152396_bib0045","first-page":"105","article-title":"Effect of probiotics on intestinal flora in patients with colon cancer undergoing chemotherapy","volume":"13","author":"Zhan","year":"2018","journal-title":"China Pract Med"},{"issue":"3","key":"10.1016\/j.soncn.2026.152396_bib0046","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3233\/MNM-200413","article-title":"Effect of synbiotic supplementation on matrix metalloproteinase enzymes, quality of life and dietary intake and weight changes in rectal cancer patients undergoing neoadjuvant chemoradiotherapy","volume":"13","author":"Farshi Radvar","year":"2020","journal-title":"Mediterr J Nutr Metab"},{"issue":"1","key":"10.1016\/j.soncn.2026.152396_bib0047","first-page":"127","article-title":"The effectiveness of yogurt+ probiotic on chemotherapy-related diarrhea in patients with colorectal cancer: a randomized clinical trial","volume":"14","author":"Mohebian","year":"2023","journal-title":"Middle East J Cancer"},{"issue":"5","key":"10.1016\/j.soncn.2026.152396_bib0048","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/apt.12878","article-title":"Systematic review: the role of the gut microbiota in chemotherapy- or radiation-induced gastrointestinal mucositis \u2013 current evidence and potential clinical applications","volume":"40","author":"Touchefeu","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.soncn.2026.152396_bib0049","doi-asserted-by":"crossref","first-page":"414","DOI":"10.3389\/fphar.2016.00414","article-title":"Chemotherapy-induced constipation and diarrhea: pathophysiology, current and emerging treatments","volume":"7","author":"McQuade","year":"2016","journal-title":"Front Pharmacol"},{"issue":"5","key":"10.1016\/j.soncn.2026.152396_bib0050","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/j.1365-2613.2009.00671.x","article-title":"Irinotecan-induced mucositis manifesting as diarrhoea corresponds with an amended intestinal flora and mucin profile","volume":"90","author":"Stringer","year":"2009","journal-title":"Int J Experimental Path"},{"key":"10.1016\/j.soncn.2026.152396_bib0051","article-title":"Synbiotics: effects of prebiotics on the growth and viability of probiotics in food matrices","volume":"32","author":"Priyanka","year":"2024","journal-title":"Bioact Carbohydr Diet Fibre"},{"issue":"24","key":"10.1016\/j.soncn.2026.152396_bib0052","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1200\/JCO.20.01296","article-title":"Antiemetics: ASCO guideline update","volume":"38","author":"Hesketh","year":"2020","journal-title":"JCO"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2023.102195","article-title":"2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting","volume":"9","author":"Herrstedt","year":"2024","journal-title":"ESMO Open"},{"issue":"2","key":"10.1016\/j.soncn.2026.152396_bib0054","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.cgh.2020.03.056","article-title":"Management of chronic abdominal distension and bloating","volume":"19","author":"Lacy","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.soncn.2026.152396_bib0055","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1516449","article-title":"Safety evaluation of irinotecan: a real-world disproportionality analysis using FAERS and JADER databases during the time period 2004-2024","volume":"16","author":"Lou","year":"2025","journal-title":"Front Pharmacol"},{"issue":"6","key":"10.1016\/j.soncn.2026.152396_bib0056","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1158\/1535-7163.MCT-15-0990","article-title":"Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms","volume":"15","author":"Wardill","year":"2016","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.soncn.2026.152396_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176614","article-title":"Mechanisms and emerging strategies for irinotecan-induced diarrhea","volume":"974","author":"Xu","year":"2024","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.soncn.2026.152396_bib0058","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3389\/fimmu.2013.00512","article-title":"Modulation of intestinal TLR4-inflammatory signaling pathways by probiotic microorganisms: lessons learned from Lactobacillus jensenii TL2937","volume":"4","author":"Villena","year":"2014","journal-title":"Front Immunol"},{"issue":"8","key":"10.1016\/j.soncn.2026.152396_bib0059","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.4049\/jimmunol.2200855","article-title":"Mechanism of TLR4-mediated anti-inflammatory response induced by exopolysaccharide from the probiotic Bacillus subtilis","volume":"211","author":"Zamora-Pineda","year":"2023","journal-title":"J Immunol"},{"issue":"42","key":"10.1016\/j.soncn.2026.152396_bib0060","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000035370","article-title":"The effect of continuous care on the recovery of patients with advanced colorectal cancer undergoing chemotherapy","volume":"102","author":"Wang","year":"2023","journal-title":"Medicine"},{"issue":"6","key":"10.1016\/j.soncn.2026.152396_bib0061","doi-asserted-by":"crossref","first-page":"778","DOI":"10.3390\/nu16060778","article-title":"Prebiotics and probiotics for gastrointestinal disorders","volume":"16","author":"Rau","year":"2024","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.soncn.2026.152396_bib0062","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e27908","article-title":"Accounting for the health risk of probiotics","volume":"10","author":"Liu","year":"2024","journal-title":"Heliyon"}],"container-title":["Seminars in Oncology Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749208126002767?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749208126002767?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:38:59Z","timestamp":1790804339000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749208126002767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":62,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S0749208126002767"],"URL":"https:\/\/doi.org\/10.1016\/j.soncn.2026.152396","relation":{},"ISSN":["0749-2081"],"issn-type":[{"value":"0749-2081","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative Effects of Microbiota-Modifying Interventions for Gastrointestinal Disorders in Adults with Colorectal Cancer: A Systematic Review and Network Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"Seminars in Oncology Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.soncn.2026.152396","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"152396"}}