{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:48:36Z","timestamp":1792633716096,"version":"4.5.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Pediatric Neurology"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.spen.2012.02.004","type":"journal-article","created":{"date-parts":[[2012,8,11]],"date-time":"2012-08-11T13:13:22Z","timestamp":1344690802000},"page":"96-100","source":"Crossref","is-referenced-by-count":126,"title":["Neurologic Complications of Influenza"],"prefix":"10.1016","volume":"19","author":[{"given":"Jeffrey J.","family":"Ekstrand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.spen.2012.02.004_bib1","series-title":"Red Book","first-page":"400","article-title":"Influenza","year":"2009"},{"key":"10.1016\/j.spen.2012.02.004_bib2","first-page":"1057","article-title":"Estimates of deaths associated with seasonal influenza\u2014United States, 1976-2007","volume":"59","year":"2010","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.spen.2012.02.004_bib3","first-page":"725","article-title":"Nervous and mental disturbances of influenza","volume":"108","author":"Jelliffe","year":"1918","journal-title":"N Y Med J"},{"key":"10.1016\/j.spen.2012.02.004_bib4","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00702-008-0161-1","article-title":"Encephalitis lethargica and influenza","volume":"116","author":"Foley","year":"2009","journal-title":"J Neural Transm"},{"key":"10.1016\/j.spen.2012.02.004_bib5","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.mehy.2009.12.012","article-title":"Influenza caused epidemic encephalitis (encephalitis lethargica): The circumstantial evidence and a challenge to the nonbelievers","volume":"74","author":"Maurizi","year":"2010","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.spen.2012.02.004_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00006205-199712000-00005","article-title":"Reye's syndrome: An update","volume":"22","author":"Ward","year":"1997","journal-title":"Nurse Pract"},{"key":"10.1016\/j.spen.2012.02.004_bib7","doi-asserted-by":"crossref","first-page":"e626","DOI":"10.1542\/peds.2004-0143","article-title":"Neurologic complications associated with influenza A in children during the 2003-2004 influenza season in Houston, Texas","volume":"114","author":"Maricich","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.spen.2012.02.004_bib8","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1086\/341407","article-title":"Encephalitis and encephalopathy associated with an influenza epidemic in Japan","volume":"35","author":"Morishima","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.spen.2012.02.004_bib9","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.jpeds.2006.11.054","article-title":"Neurologic complications in children hospitalized with influenza: Characteristics, incidence, and risk factors","volume":"150","author":"Newland","year":"2007","journal-title":"J Pediatr"},{"key":"10.1016\/j.spen.2012.02.004_bib10","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/INF.0b013e31816507b2","article-title":"Acute childhood encephalitis and encephalopathy associated with influenza: A prospective 11-year review","volume":"27","author":"Amin","year":"2008","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.spen.2012.02.004_bib11","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/ana.22184","article-title":"Heightened neurologic complications in children with pandemic H1N1 influenza","volume":"68","author":"Ekstrand","year":"2010","journal-title":"Ann Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib12","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.pediatrneurol.2010.08.011","article-title":"Pediatric neurologic complications associated with influenza A H1N1","volume":"44","author":"Landau","year":"2011","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib13","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.pediatrneurol.2011.02.010","article-title":"Neurologic manifestations of novel influenza A (H1N1) virus infection in childhood","volume":"45","author":"Ozkan","year":"2011","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib14","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s00431-010-1352-y","article-title":"Neurological complications of pandemic influenza (H1N1) in children","volume":"170","author":"Yildizda\u015f","year":"2011","journal-title":"Eur J Pediatr"},{"issue":"suppl 1","key":"10.1016\/j.spen.2012.02.004_bib15","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1177\/08830738020170010601","article-title":"Febrile seizures","volume":"17","author":"Shinnar","year":"2002","journal-title":"J Child Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib16","doi-asserted-by":"crossref","first-page":"E63","DOI":"10.1542\/peds.108.4.e63","article-title":"Influenza A infection is an important cause of febrile seizures","volume":"108","author":"Chiu","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.spen.2012.02.004_bib17","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.pediatrneurol.2006.07.005","article-title":"Influenza A and febrile seizures in childhood","volume":"35","author":"Kwong","year":"2006","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib18","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0140-6736(98)12449-2","article-title":"PCR on cerebrospinal fluid to show influenza-associated acute encephalopathy or encephalitis","volume":"352","author":"Fujimoto","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.spen.2012.02.004_bib19","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/(SICI)1096-9071(199908)58:4<420::AID-JMV16>3.0.CO;2-T","article-title":"Detection of influenza virus RNA by reverse transcription-PCR and proinflammatory cytokines in influenza-virus-associated encephalopathy","volume":"58","author":"Ito","year":"1999","journal-title":"J Med Virol"},{"key":"10.1016\/j.spen.2012.02.004_bib20","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/clind\/24.4.736","article-title":"Use of the polymerase chain reaction for demonstration of influenza virus dissemination in children","volume":"24","author":"Mori","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.spen.2012.02.004_bib21","first-page":"773","article-title":"Neurologic complications associated with novel influenza A (H1N1) virus infection in children\u2014Dallas, Texas, May 2009","volume":"58","year":"2009","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.spen.2012.02.004_bib22","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.3174\/ajnr.A1903","article-title":"Influenza A encephalopathy, cerebral vasculopathy, and posterior reversible encephalopathy syndrome: Combined occurrence in a 3-year-old child","volume":"31","author":"Bartynski","year":"2010","journal-title":"Am J Neuroradiol"},{"key":"10.1016\/j.spen.2012.02.004_bib23","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s00117-011-2131-0","article-title":"Transient splenial lesion in influenza A H1N1 2009 infection","volume":"51","author":"Linden","year":"2011","journal-title":"Radiologe"},{"key":"10.1016\/j.spen.2012.02.004_bib24","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/INF.0b013e3181f2de6f","article-title":"Neurologic manifestations of pediatric novel H1N1 influenza infection","volume":"30","author":"Rellosa","year":"2011","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.spen.2012.02.004_bib25","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1600-0404.2007.00809.x","article-title":"Acute encephalopathy associated with influenza and other viral infections","volume":"186","author":"Mizuguchi","year":"2007","journal-title":"Acta Neurol Scand Suppl"},{"key":"10.1016\/j.spen.2012.02.004_bib26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0387-7604(96)00063-0","article-title":"Acute necrotizing encephalopathy of childhood: A novel form of acute encephalopathy prevalent in Japan and Taiwan","volume":"19","author":"Mizuguchi","year":"1997","journal-title":"Brain Dev"},{"key":"10.1016\/j.spen.2012.02.004_bib27","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1055\/s-2006-924164","article-title":"Influenza A-associated acute necrotizing encephalopathy","volume":"37","author":"Olgar","year":"2006","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.spen.2012.02.004_bib28","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1136\/jnnp.58.5.555","article-title":"Acute necrotising encephalopathy of childhood: A new syndrome presenting with multifocal, symmetric brain lesions","volume":"58","author":"Mizuguchi","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.spen.2012.02.004_bib29","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1469-8749.2009.03405.x","article-title":"Recurrent acute necrotizing encephalopathy following influenza A in a genetically predisposed family","volume":"52","author":"Gika","year":"2010","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib30","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1177\/088307380101601204","article-title":"Study of influenza-associated encephalitis\/encephalopathy in children during the 1997 to 2001 influenza seasons","volume":"16","author":"Yoshikawa","year":"2001","journal-title":"J Child Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib31","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.virusres.2004.02.016","article-title":"Influenza-associated acute encephalopathy in Japanese children in 1994-2002","volume":"103","author":"Togashi","year":"2004","journal-title":"Virus Res"},{"key":"10.1016\/j.spen.2012.02.004_bib32","series-title":"2003 Annual Report of the Research Committee for Research on Emerging and Re-emerging Diseases","first-page":"11","article-title":"On the nationwide surveillance of influenza encephalopathy in the year 2002\/2003","author":"Morishima","year":"2004"},{"key":"10.1016\/j.spen.2012.02.004_bib33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000206854","article-title":"Encephalitis after influenza in Sweden 1987-1998: A rare complication of a common infection","volume":"61","author":"Hjalmarsson","year":"2009","journal-title":"Eur Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib34","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ejpn.2004.06.002","article-title":"Encephalopathy associated with influenza A","volume":"8","author":"Smidt","year":"2004","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib35","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1086\/367623","article-title":"Acute encephalopathy associated with influenza A virus infection","volume":"36","author":"Steininger","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.spen.2012.02.004_bib36","first-page":"504","article-title":"Influenza A associated morbidity and mortality in a paediatric intensive care unit","volume":"28","author":"Milne","year":"2004","journal-title":"Commun Dis Intell"},{"key":"10.1016\/j.spen.2012.02.004_bib37","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1440-1754.2008.01390.x","article-title":"Emergence of acute necrotising encephalopathy in Australia","volume":"44","author":"Troedson","year":"2008","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.spen.2012.02.004_bib38","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1177\/088307380502000612","article-title":"Acute necrotizing encephalopathy in Caucasian children: Two cases and review of the literature","volume":"20","author":"Kirton","year":"2005","journal-title":"J Child Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib39","first-page":"837","article-title":"Severe morbidity and mortality associated with influenza in children and young adults\u2014Michigan, 2003","volume":"52","year":"2003","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.spen.2012.02.004_bib40","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1097\/01.inf.0000115631.99896.41","article-title":"Influenza A virus-associated acute necrotizing encephalopathy in the United States","volume":"23","author":"Weitkamp","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.spen.2012.02.004_bib41","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/PCC.0b013e3181cf4652","article-title":"Neurological sequelae of 2009 influenza A (H1N1) in children: A case series observed during a pandemic","volume":"11","author":"Baltagi","year":"2010","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.spen.2012.02.004_bib42","doi-asserted-by":"crossref","first-page":"396","DOI":"10.3174\/ajnr.A2058","article-title":"Acute necrotizing encephalopathy in a child during the 2009 influenza A (H1N1) pandemia: MR imaging in diagnosis and follow-up","volume":"31","author":"Ormitti","year":"2010","journal-title":"Am J Neuroradiol"},{"key":"10.1016\/j.spen.2012.02.004_bib43","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/0883073810382660","article-title":"Miller Fisher syndrome in a toddler with influenza A (pH1N1) infection","volume":"26","author":"Costiniuk","year":"2011","journal-title":"J Child Neurol"},{"key":"10.1016\/j.spen.2012.02.004_bib44","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1473-3099(10)70140-7","article-title":"Guillain-Barre syndrome after exposure to influenza virus","volume":"10","author":"Lehmann","year":"2010","journal-title":"Lancet Infect Dis"}],"container-title":["Seminars in Pediatric Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071909112000058?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071909112000058?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T10:28:22Z","timestamp":1714300102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1071909112000058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S1071909112000058"],"URL":"https:\/\/doi.org\/10.1016\/j.spen.2012.02.004","relation":{},"ISSN":["1071-9091"],"issn-type":[{"value":"1071-9091","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}