{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:31:43Z","timestamp":1789234303373,"version":"build-2803163510"},"reference-count":44,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["patient-research.elsevier.com","thespinejournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Spine Journal"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.spinee.2013.10.049","type":"journal-article","created":{"date-parts":[[2013,11,16]],"date-time":"2013-11-16T17:00:32Z","timestamp":1384621232000},"page":"1902-1908","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Persistent hypoalbuminemia is a predictor of outcome in cervical spinal cord injury"],"prefix":"10.1016","volume":"14","author":[{"given":"Guo-Xin","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Qian","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Zhu","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.spinee.2013.10.049_bib1","series-title":"Spinal Cord Injury Facts and Figures","doi-asserted-by":"crossref","year":"2008","DOI":"10.1111\/j.1365-2044.1996.tb07883.x"},{"key":"10.1016\/j.spinee.2013.10.049_bib2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/BF03013253","article-title":"Predictors of hospital mortality and mechanical ventilation in patients with cervical spinal cord injury","volume":"45","author":"Claxton","year":"1998","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.spinee.2013.10.049_bib3","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1136\/jnnp.52.3.403","article-title":"Initial factors predicting survival in patients with a spinal cord injury","volume":"52","author":"Daverat","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.spinee.2013.10.049_bib4","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.amjsurg.2005.05.051","article-title":"Patterns of injury and functional outcome after hanging: analysis of National Trauma Data Bank","volume":"190","author":"Martin","year":"2005","journal-title":"Am J Surg"},{"key":"10.1016\/j.spinee.2013.10.049_bib5","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/j.1365-2044.1996.tb07883.x","article-title":"The prognostic value of serial measurements of serum albumin concentration in patients admitted to an intensive care unit","volume":"51","author":"McCluskey","year":"1996","journal-title":"Anaesthesia"},{"key":"10.1016\/j.spinee.2013.10.049_bib6","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/01.SLA.0000055547.93484.87","article-title":"Hypoalbuminemia in acute illness: Is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials","volume":"237","author":"Vincent","year":"2003","journal-title":"Ann Surg"},{"key":"10.1016\/j.spinee.2013.10.049_bib7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jcrc.2004.02.011","article-title":"Serum levels of calcium and albumin in survivors versus nonsurvivors after critical injury","volume":"19","author":"Ward","year":"2004","journal-title":"J Crit Care"},{"key":"10.1016\/j.spinee.2013.10.049_bib8","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/10790268.1997.11719485","article-title":"Anemia and serum protein deficiencies in patients with traumatic spinal cord injury","volume":"20","author":"Lipetz","year":"1997","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.spinee.2013.10.049_bib9","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/sc.2009.163","article-title":"Anemia and hypoalbuminemia of chronic spinal cord injury: prevalence and prognostic significance","volume":"48","author":"Frisbie","year":"2010","journal-title":"Spinal Cord"},{"key":"10.1016\/j.spinee.2013.10.049_bib10","first-page":"407","article-title":"Guidelines for the management of acute cervical spine and spinal cord injuries","volume":"49","author":"Hadley","year":"2002","journal-title":"Clin Neurosurg"},{"key":"10.1016\/j.spinee.2013.10.049_bib11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0140-6736(74)91639-0","article-title":"Assessment of coma and impaired consciousness. A practical scale","volume":"2","author":"Teasdale","year":"1974","journal-title":"Lancet"},{"key":"10.1016\/j.spinee.2013.10.049_bib12","doi-asserted-by":"crossref","first-page":"3137","DOI":"10.1097\/00003246-200009000-00001","article-title":"Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group","volume":"28","author":"Mangialardi","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.spinee.2013.10.049_bib13","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/sc.1987.48","article-title":"Respiratory aspects of spinal cord injury management","volume":"25","author":"Carter","year":"1987","journal-title":"Paraplegia"},{"key":"10.1016\/j.spinee.2013.10.049_bib14","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1097\/00007632-199410150-00011","article-title":"Respiratory complications after cervical spinal cord injury","volume":"19","author":"Lemons","year":"1994","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2013.10.049_bib15","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/0003-9993(94)90027-2","article-title":"Incidence of respiratory complications following SCI","volume":"75","author":"Jackson","year":"1994","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.spinee.2013.10.049_bib16","first-page":"605","article-title":"The effects of hypoproteinemia and volume expansion on lung and soft tissue transvascular fluid filtration","volume":"105","author":"Harms","year":"1989","journal-title":"Surgery"},{"key":"10.1016\/j.spinee.2013.10.049_bib17","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1179\/2045772311Y.0000000024","article-title":"Factors associated with early mortality after cervical spinal cord injury","volume":"34","author":"Shao","year":"2011","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.spinee.2013.10.049_bib18","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/sc.1989.3","article-title":"Cervical spinal cord injury: the correlations of initial clinical features and blood gas analyses with early prognosis","volume":"27","author":"Myllynen","year":"1989","journal-title":"Paraplegia"},{"key":"10.1016\/j.spinee.2013.10.049_bib19","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/sj.sc.3101382","article-title":"Nutritional and immune status following spinal cord injury: a case controlled study","volume":"40","author":"Lynch","year":"2002","journal-title":"Spinal Cord"},{"key":"10.1016\/j.spinee.2013.10.049_bib20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0261-5614(99)80070-3","article-title":"Changes in weight, fluid balance and serum albumin in patients referred for nutritional support","volume":"18","author":"Lobo","year":"1999","journal-title":"Clin Nutr"},{"key":"10.1016\/j.spinee.2013.10.049_bib21","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0140-6736(85)91447-3","article-title":"Increased vascular permeability: a major cause of hypoalbuminaemia in disease and injury","volume":"1","author":"Fleck","year":"1985","journal-title":"Lancet"},{"key":"10.1016\/j.spinee.2013.10.049_bib22","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/0026-0495(94)90117-1","article-title":"Transcapillary escape rate of albumin positively correlates with plasma albumin concentration in acute but not in chronic inflammatory disease","volume":"43","author":"Ballmer","year":"1994","journal-title":"Metabolism"},{"key":"10.1016\/j.spinee.2013.10.049_bib23","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/sc.1974.21","article-title":"Elimination rate of human serum albumin in paraplegic patients","volume":"12","author":"Ring","year":"1974","journal-title":"Paraplegia"},{"key":"10.1016\/j.spinee.2013.10.049_bib24","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1097\/TA.0b013e31803428cc","article-title":"Serum albumin level as a predictor of outcome in traumatic brain injury: potential for treatment","volume":"64","author":"Bernard","year":"2008","journal-title":"J Trauma"},{"key":"10.1016\/j.spinee.2013.10.049_bib25","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/sc.1983.34","article-title":"A review and update of experimental and clinical studies of spinal cord injury","volume":"21","author":"Collins","year":"1983","journal-title":"Paraplegia"},{"key":"10.1016\/j.spinee.2013.10.049_bib26","doi-asserted-by":"crossref","first-page":"743","DOI":"10.3171\/jns.1985.62.5.0743","article-title":"The role of monamines in experimental spinal cord injury in rats. Relationship between Na + - K+ - ATP ase and lipid peroxidation","volume":"62","author":"Kurihara","year":"1985","journal-title":"J Neurosurg"},{"key":"10.1016\/j.spinee.2013.10.049_bib27","first-page":"S31","article-title":"Inhibition of lipid peroxidation in CNS trauma","volume":"8","author":"Hall","year":"1991","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.spinee.2013.10.049_bib28","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1161\/01.STR.25.2.445","article-title":"Nitric oxide synthase inbition alters cerebral blood flow and oxygen balance in focal cerbral ischemia in rats","volume":"25","author":"Wei","year":"1994","journal-title":"Stroke"},{"key":"10.1016\/j.spinee.2013.10.049_bib29","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1161\/01.STR.0000110790.05859.DA","article-title":"Human serum albumin and its N-terminal tetrapeptide (DAHK) block oxidant-induced neuronal death","volume":"35","author":"Gum","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.spinee.2013.10.049_bib30","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1365-2362.1995.tb01739.x","article-title":"Albumin affects erythrocyte aggregation and sedimentation","volume":"25","author":"Reinhart","year":"1995","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.spinee.2013.10.049_bib31","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1242\/jcs.109.10.2571","article-title":"Serum albumin is a specific inhibitor of apoptosis in human endothelial cells","volume":"109","author":"Zoellner","year":"1996","journal-title":"J Cell Sci"},{"key":"10.1016\/j.spinee.2013.10.049_bib32","doi-asserted-by":"crossref","first-page":"E50","DOI":"10.1161\/01.RES.86.3.e50","article-title":"Regulation of endothelial nitric oxide synthase expression by albumin-derived advanced glycosylation end products","volume":"86","author":"Rojas","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.spinee.2013.10.049_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1098-1136(19990101)25:1<1::AID-GLIA1>3.0.CO;2-2","article-title":"The effect of albumin on astrocyte energy metabolism is not brought about through the control of cytosolic Ca2+ concentrations but by free-fatty acid sequestration","volume":"25","author":"Tabernero","year":"1999","journal-title":"Glia"},{"key":"10.1016\/j.spinee.2013.10.049_bib34","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1161\/hs0402.105555","article-title":"Albumin therapy of transient focal cerebral ischemia: in vivo analysis of dynamic microvascular responses","volume":"33","author":"Belayev","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.spinee.2013.10.049_bib35","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1227\/00006123-199308000-00017","article-title":"Beneficial effect of prolonged administration of albumin on ischemic cerebral edema and infarction after occlusion of middle cerebral artery in rats","volume":"33","author":"Matsui","year":"1993","journal-title":"Neurosurgery"},{"key":"10.1016\/j.spinee.2013.10.049_bib36","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1002\/jnr.21265","article-title":"Serum albumin improves recovery from spinal cord injury","volume":"15","author":"Cain","year":"2007","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.spinee.2013.10.049_bib37","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1161\/01.STR.32.2.553","article-title":"Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window","volume":"32","author":"Belayev","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.spinee.2013.10.049_bib38","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1001\/archsurg.1985.01390320035006","article-title":"Postoperative albumin infusion therapy based on colloid osmotic pressure","volume":"120","author":"Grundmann","year":"1985","journal-title":"Arch Surg"},{"key":"10.1016\/j.spinee.2013.10.049_bib39","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1365-2044.1992.tb01942.x","article-title":"Colloid solutions in the critically ill. A randomized comparison of albumin and polygeline. 2. Serum albumin concentration and the incidences of pulmonary oedema and acute renal failure","volume":"47","author":"Stockwell","year":"1992","journal-title":"Anaesthesia"},{"key":"10.1016\/j.spinee.2013.10.049_bib40","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00003246-199202000-00001","article-title":"Time to abandon routine albumin supplementation","volume":"20","author":"Blackburn","year":"1992","journal-title":"Crit Care Med"},{"key":"10.1016\/j.spinee.2013.10.049_bib41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1136\/bmj.317.7153.235","article-title":"Human albumin administration in critically ill patients: systematic review of randomised controlled trials","volume":"317","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.spinee.2013.10.049_bib42","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1097\/01.CCM.0000171539.47006.02","article-title":"A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury","volume":"33","author":"Martin","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.spinee.2013.10.049_bib43","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1097\/01.CCM.0000239119.57544.0C","article-title":"Albumin administration improves organ function in critically ill hypoalbuminemic patients: A prospective, randomized, controlled, pilot study","volume":"34","author":"Dubois","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.spinee.2013.10.049_bib44","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/00003246-200301000-00029","article-title":"Albumin resuscitation increases cardiomyocyte contractility and decreases nitric oxide synthase II expression in rat endotoxemia","volume":"31","author":"Walley","year":"2003","journal-title":"Crit Care Med"}],"container-title":["The Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1529943013017178?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1529943013017178?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T13:53:52Z","timestamp":1647093232000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1529943013017178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":44,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S1529943013017178"],"URL":"https:\/\/doi.org\/10.1016\/j.spinee.2013.10.049","relation":{},"ISSN":["1529-9430"],"issn-type":[{"value":"1529-9430","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistent hypoalbuminemia is a predictor of outcome in cervical spinal cord injury","name":"articletitle","label":"Article Title"},{"value":"The Spine Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.spinee.2013.10.049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}