{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:43:40Z","timestamp":1787496220478,"version":"build-2736575974"},"reference-count":31,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","thespinejournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Spine Journal"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.spinee.2018.03.002","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T13:39:29Z","timestamp":1520516369000},"page":"1779-1786","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Effect of posterior instrumented fusion on three-dimensional volumetric growth of cervical ossification of the posterior longitudinal ligament: a multiple regression analysis"],"prefix":"10.1016","volume":"18","author":[{"given":"Jong Joo","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Ah","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keung Nyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do Heum","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Chul","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.spinee.2018.03.002_bib0010","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1097\/BRS.0b013e31817f988c","article-title":"Radiographic predictors for the development of myelopathy in patients with ossification of the posterior longitudinal ligament: a multicenter cohort study","volume":"33","author":"Matsunaga","year":"2008","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0015","doi-asserted-by":"crossref","first-page":"E309","DOI":"10.1097\/BRS.0b013e318241ad33","article-title":"Ossification of the posterior longitudinal ligament of the cervical spine: etiology and natural history","volume":"37","author":"Matsunaga","year":"2012","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0020","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.wneu.2016.02.054","article-title":"Clinical characteristics and surgical outcome of revision surgery in patients with cervical ossification of the posterior longitudinal ligament","volume":"90","author":"Ha","year":"2016","journal-title":"World Neurosurg"},{"key":"10.1016\/j.spinee.2018.03.002_bib0025","doi-asserted-by":"crossref","first-page":"E101","DOI":"10.1097\/BRS.0b013e31818a3135","article-title":"A patient with two re-surgeries for delayed myelopathy due to progression of ossification of the posterior longitudinal ligaments after cervical laminoplasty","volume":"34","author":"Tokuhashi","year":"2009","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0030","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3171\/2012.9.SPINE12548","article-title":"Does ossification of the posterior longitudinal ligament progress after laminoplasty? Radiographic and clinical evidence of ossification of the posterior longitudinal ligament lesion growth and the risk factors for late neurologic deterioration","volume":"17","author":"Fargen","year":"2012","journal-title":"J Neurosurg Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0035","doi-asserted-by":"crossref","first-page":"E551","DOI":"10.1097\/BRS.0b013e31814614f3","article-title":"How does the ossification area of the posterior longitudinal ligament thicken following cervical laminoplasty?","volume":"32","author":"Hori","year":"2007","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0040","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1097\/01.brs.0000245870.97231.65","article-title":"How does the ossification area of the posterior longitudinal ligament progress after cervical laminoplasty?","volume":"31","author":"Hori","year":"2006","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0045","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/00007632-198107000-00005","article-title":"Operative results and postoperative progression of ossification among patients with ossification of cervical posterior longitudinal ligament","volume":"6","author":"Hirabayashi","year":"1981","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0050","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.2106\/00004623-200112000-00005","article-title":"Progression of ossification of the posterior longitudinal ligament following en bloc cervical laminoplasty","volume":"83-a","author":"Kawaguchi","year":"2001","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.spinee.2018.03.002_bib0055","first-page":"271","article-title":"Radiological study of cervical ossification of the posterior longitudinal ligament","volume":"12","author":"Takatsu","year":"1999","journal-title":"J Spinal Disord"},{"key":"10.1016\/j.spinee.2018.03.002_bib0060","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1007\/s00586-015-4328-9","article-title":"Posterior instrumented fusion suppresses the progression of ossification of the posterior longitudinal ligament: a comparison of laminoplasty with and without instrumented fusion by three-dimensional analysis","volume":"25","author":"Katsumi","year":"2016","journal-title":"Eur Spine J"},{"key":"10.1016\/j.spinee.2018.03.002_bib0065","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1007\/s00586-013-2989-9","article-title":"Three-dimensional evaluation of volume change in ossification of the posterior longitudinal ligament of the cervical spine using computed tomography","volume":"22","author":"Izumi","year":"2013","journal-title":"Eur Spine J"},{"key":"10.1016\/j.spinee.2018.03.002_bib0070","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3171\/2011.11.SPINE11502","article-title":"Three-dimensional measurement of growth of ossification of the posterior longitudinal ligament","volume":"16","author":"Fujimori","year":"2012","journal-title":"J Neurosurg Spine"},{"issue":"2 Suppl.","key":"10.1016\/j.spinee.2018.03.002_bib0075","first-page":"180","article-title":"Long-term results of expansive laminoplasty for ossification of the posterior longitudinal ligament of the cervical spine: more than 10 years follow up","volume":"96","author":"Iwasaki","year":"2002","journal-title":"J Neurosurg"},{"key":"10.1016\/j.spinee.2018.03.002_bib0080","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s00264-008-0609-9","article-title":"Long-term outcome of laminectomy and instrumented fusion for cervical ossification of the posterior longitudinal ligament","volume":"33","author":"Chen","year":"2009","journal-title":"Int Orthop"},{"key":"10.1016\/j.spinee.2018.03.002_bib0085","first-page":"1081","article-title":"Laminectomy and posterior cervical plating for multilevel cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament: effects on cervical alignment, spinal cord compression, and neurological outcome","volume":"52","author":"Houten","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.spinee.2018.03.002_bib0090","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jocn.2016.06.013","article-title":"Addition of instrumented fusion after posterior decompression surgery suppresses thickening of ossification of the posterior longitudinal ligament of the cervical spine","volume":"34","author":"Ota","year":"2016","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.spinee.2018.03.002_bib0095","first-page":"425","article-title":"The ossification of the posterior longitudinal ligament of the spine (OPLL). The Investigation Committee on OPLL of the Japanese Ministry of Public Health and Welfare","volume":"55","year":"1981","journal-title":"Nippon Seikeigeka Gakkai Zasshi"},{"key":"10.1016\/j.spinee.2018.03.002_bib0100","article-title":"Natural history of the ossification of cervical posterior longitudinal ligament: a three dimensional analysis","author":"Katsumi","year":"2017","journal-title":"Int Orthop"},{"key":"10.1016\/j.spinee.2018.03.002_bib0105","doi-asserted-by":"crossref","first-page":"E9","DOI":"10.1097\/BSD.0000000000000058","article-title":"Expansive laminoplasty versus laminectomy alone versus laminectomy and fusion for cervical ossification of the posterior longitudinal ligament: is there a difference in the clinical outcome and sagittal alignment?","volume":"29","author":"Lee","year":"2016","journal-title":"Clin Spine Surg"},{"key":"10.1016\/j.spinee.2018.03.002_bib0110","doi-asserted-by":"crossref","first-page":"234","DOI":"10.3171\/spi.2006.5.3.234","article-title":"Repetitive tensile stress to rat caudal vertebrae inducing cartilage formation in the spinal ligaments: a possible role of mechanical stress in the development of ossification of the spinal ligaments","volume":"5","author":"Tsukamoto","year":"2006","journal-title":"J Neurosurg Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0115","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3171\/spi.2005.3.1.0017","article-title":"Multicenter study investigating the postoperative progression of ossification of the posterior longitudinal ligament in the cervical spine: a new computer-assisted measurement","volume":"3","author":"Chiba","year":"2005","journal-title":"J Neurosurg Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0120","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1007\/s00774-004-0531-1","article-title":"Dietary habits and risk of ossification of the posterior longitudinal ligaments of the spine (OPLL); findings from a case-control study in Japan","volume":"22","author":"Okamoto","year":"2004","journal-title":"J Bone Miner Metab"},{"key":"10.1016\/j.spinee.2018.03.002_bib0125","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2188\/jea.14.168","article-title":"Sleeping habit and other life styles in the prime of life and risk for ossification of the posterior longitudinal ligament of the spine (OPLL): a case-control study in Japan","volume":"14","author":"Washio","year":"2004","journal-title":"J Epidemiol"},{"key":"10.1016\/j.spinee.2018.03.002_bib0130","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1007\/s007760050169","article-title":"Recent progress in the study of pathogenesis of ossification of the posterior longitudinal ligament","volume":"5","author":"Sakou","year":"2000","journal-title":"J Orthop Sci"},{"issue":"2 Suppl.","key":"10.1016\/j.spinee.2018.03.002_bib0135","first-page":"168","article-title":"Pathogenesis of myelopathy in patients with ossification of the posterior longitudinal ligament","volume":"96","author":"Matsunaga","year":"2002","journal-title":"J Neurosurg"},{"key":"10.1016\/j.spinee.2018.03.002_bib0140","doi-asserted-by":"crossref","first-page":"E417","DOI":"10.1097\/BRS.0000000000000187","article-title":"Spontaneous reduction in ossification of the posterior longitudinal ligament of the thoracic spine after posterior spinal fusion without decompression: a case report","volume":"39","author":"Kimura","year":"2014","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0145","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1007\/s00586-015-3888-z","article-title":"Bone union and remodelling of the non-ossified segment in thoracic ossification of the posterior longitudinal ligament after posterior decompression and fusion surgery","volume":"24","author":"Koda","year":"2015","journal-title":"Eur Spine J"},{"key":"10.1016\/j.spinee.2018.03.002_bib0150","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3340\/jkns.2015.0708.014","article-title":"Inter- and intra-observer variability of the volume of cervical ossification of the posterior longitudinal ligament using medical image processing software","volume":"60","author":"Shin","year":"2017","journal-title":"J Korean Neurosurg Soc"},{"key":"10.1016\/j.spinee.2018.03.002_bib0155","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1097\/BRS.0000000000001072","article-title":"Usefulness of 3-dimensional measurement of ossification of the posterior longitudinal ligament (OPLL) in patients with OPLL-induced myelopathy","volume":"40","author":"Lee","year":"2015","journal-title":"Spine"},{"key":"10.1016\/j.spinee.2018.03.002_bib0160","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/BRS.0000000000001933","article-title":"Are there differences in the progression of ossification of the posterior longitudinal ligament following laminoplasty versus fusion? A meta-analysis","volume":"42","author":"Lee","year":"2017","journal-title":"Spine"}],"container-title":["The Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1529943018300858?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1529943018300858?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T16:06:22Z","timestamp":1547568382000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1529943018300858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":31,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S1529943018300858"],"URL":"https:\/\/doi.org\/10.1016\/j.spinee.2018.03.002","relation":{},"ISSN":["1529-9430"],"issn-type":[{"value":"1529-9430","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of posterior instrumented fusion on three-dimensional volumetric growth of cervical ossification of the posterior longitudinal ligament: a multiple regression analysis","name":"articletitle","label":"Article Title"},{"value":"The Spine Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.spinee.2018.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}