{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T03:40:35Z","timestamp":1759549235758,"version":"build-2065373602"},"reference-count":9,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Stem Cell"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.stem.2025.08.008","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T03:16:30Z","timestamp":1759547790000},"page":"1481-1482","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unmasking cancer\u2019s hidden nerve route with patient-derived organoids"],"prefix":"10.1016","volume":"32","author":[{"given":"Kevin M.","family":"Waters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akil","family":"Merchant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.stem.2025.08.008_bib1","first-page":"1595","article-title":"A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer","volume":"32","author":"Chan","year":"2025","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stem.2025.08.008_bib2","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.medj.2024.08.010","article-title":"Patient-derived organoids in precision cancer medicine","volume":"5","author":"Tong","year":"2024","journal-title":"Med"},{"key":"10.1016\/j.stem.2025.08.008_bib3","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.ccell.2023.02.012","article-title":"Cancer hallmarks intersect with neuroscience in the tumor microenvironment","volume":"41","author":"Hanahan","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.stem.2025.08.008_bib4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ccell.2016.11.005","article-title":"Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling","volume":"31","author":"Hayakawa","year":"2017","journal-title":"Cancer Cell"},{"key":"10.1016\/j.stem.2025.08.008_bib5","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1038\/s41586-025-08591-1","article-title":"Nociceptive neurons promote gastric tumour progression via a CGRP\u2013RAMP1 axis","volume":"640","author":"Zhi","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.stem.2025.08.008_bib6","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.chembiol.2023.01.005","article-title":"Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production","volume":"30","author":"Nguyen","year":"2023","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.stem.2025.08.008_bib7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1039\/D2CB00172A","article-title":"SREBP activation contributes to fatty acid accumulations in necroptosis","volume":"4","author":"Lu","year":"2023","journal-title":"RSC Chem. Biol."},{"key":"10.1016\/j.stem.2025.08.008_bib8","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/s41568-022-00543-5","article-title":"Acetyl-CoA metabolism in cancer","volume":"23","author":"Guertin","year":"2023","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.stem.2025.08.008_bib9","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0022-2275(20)37449-6","article-title":"Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin","volume":"38","author":"Morand","year":"1997","journal-title":"J. Lipid Res."}],"container-title":["Cell Stem Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934590925003005?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934590925003005?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T03:19:46Z","timestamp":1759547986000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934590925003005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1934590925003005"],"URL":"https:\/\/doi.org\/10.1016\/j.stem.2025.08.008","relation":{},"ISSN":["1934-5909"],"issn-type":[{"value":"1934-5909","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unmasking cancer\u2019s hidden nerve route with patient-derived organoids","name":"articletitle","label":"Article Title"},{"value":"Cell Stem Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.stem.2025.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.stem.2025.08.006","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}