{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T09:56:23Z","timestamp":1786528583893,"version":"build-2736575974"},"reference-count":52,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004739","name":"Chinese Academy of Sciences Youth Innovation Promotion Association","doi-asserted-by":"publisher","award":["2021364"],"award-info":[{"award-number":["2021364"]}],"id":[{"id":"10.13039\/501100004739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271403"],"award-info":[{"award-number":["32271403"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52425309"],"award-info":[{"award-number":["52425309"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20690"],"award-info":[{"award-number":["U23A20690"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["525B2190"],"award-info":[{"award-number":["525B2190"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018601","name":"Guangdong Special Support Plan","doi-asserted-by":"publisher","award":["2023TQ07A534"],"award-info":[{"award-number":["2023TQ07A534"]}],"id":[{"id":"10.13039\/501100018601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFB3804500"],"award-info":[{"award-number":["2022YFB3804500"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["RCJC20210706092010008"],"award-info":[{"award-number":["RCJC20210706092010008"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["JCYJ20240813154700001"],"award-info":[{"award-number":["JCYJ20240813154700001"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Stem Cell"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.stem.2026.03.002","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T15:29:39Z","timestamp":1774538979000},"page":"837-852.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Preservation of chondrocyte microspheroids by local sustained hydrogen supply improves osteoarthritic cartilage repair"],"prefix":"10.1016","volume":"33","author":[{"given":"Shengqiang","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingrui","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sizhen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danyang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingting","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Shangguan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengji","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanglin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjiang","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0689-8838","authenticated-orcid":false,"given":"Qianjun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.stem.2026.03.002_bib1","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1126\/science.add6492","article-title":"Emerging frontiers in regenerative medicine","volume":"380","author":"McKinley","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.stem.2026.03.002_bib2","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/s41578-018-0027-6","article-title":"Tissue repair and regeneration with endogenous stem cells","volume":"3","author":"Xia","year":"2018","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.stem.2026.03.002_bib3","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/nm.3627","article-title":"Translational strategies and challenges in regenerative medicine","volume":"20","author":"Dimmeler","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.stem.2026.03.002_bib4","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s44222-024-00238-6","article-title":"Encapsulated islet transplantation","volume":"3","author":"Liu","year":"2025","journal-title":"Nat. Rev. Bioeng."},{"key":"10.1016\/j.stem.2026.03.002_bib5","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S0140-6736(24)00693-7","article-title":"Acute liver failure","volume":"404","author":"Maiwall","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.stem.2026.03.002_bib6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrrheum.2014.157","article-title":"Repair and tissue engineering techniques for articular cartilage","volume":"11","author":"Makris","year":"2015","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.stem.2026.03.002_bib7","doi-asserted-by":"crossref","first-page":"36","DOI":"10.7150\/ijms.21666","article-title":"Ethical and safety issues of stem cell-based therapy","volume":"15","author":"Volarevic","year":"2018","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.stem.2026.03.002_bib8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.stem.2015.06.007","article-title":"Stem cell therapies in clinical trials: progress and challenges","volume":"17","author":"Trounson","year":"2015","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stem.2026.03.002_bib9","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-019-1165-5","article-title":"Stem cells: past, present, and future","volume":"10","author":"Zakrzewski","year":"2019","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.stem.2026.03.002_bib10","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/s44222-024-00214-0","article-title":"Designing drug delivery systems for cell therapy","volume":"2","author":"Wang","year":"2024","journal-title":"Nat. Rev. Bioeng."},{"key":"10.1016\/j.stem.2026.03.002_bib11","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/s41578-024-00766-y","article-title":"Delivering living medicines with biomaterials","volume":"10","author":"Harimoto","year":"2025","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.stem.2026.03.002_bib12","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/s41584-023-00979-5","article-title":"Failure of cartilage regeneration: emerging hypotheses and related therapeutic strategies","volume":"19","author":"Muthu","year":"2023","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.stem.2026.03.002_bib13","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/s41584-019-0255-1","article-title":"Surgical and tissue engineering strategies for articular cartilage and meniscus repair","volume":"15","author":"Kwon","year":"2019","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.stem.2026.03.002_bib14","article-title":"The use of autologous chondrocyte transplantation for the treatment of osteoarthritis: a systematic review of clinical trials","volume":"26","author":"Fares","year":"2024","journal-title":"Cell Tissue Bank."},{"key":"10.1016\/j.stem.2026.03.002_bib15","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1007\/s00167-022-07030-2","article-title":"Autologous chondrocyte implantation provides good long-term clinical results in the treatment of knee osteoarthritis: a systematic review.","volume":"31","author":"Colombini","year":"2023","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"10.1016\/j.stem.2026.03.002_bib16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1365-2613.2012.00837.x","article-title":"Cell sources for the regeneration of articular cartilage: the past, the horizon and the future","volume":"93","author":"Oldershaw","year":"2012","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1016\/j.stem.2026.03.002_bib17","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0092-8674(82)90027-7","article-title":"Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels","volume":"30","author":"Benya","year":"1982","journal-title":"Cell"},{"key":"10.1016\/j.stem.2026.03.002_bib18","article-title":"Regenerative medicine: a review of the evolution of autologous chondrocyte implantation (ACI) therapy","volume":"6","author":"Davies","year":"2019","journal-title":"Bioengineering (Basel)"},{"key":"10.1016\/j.stem.2026.03.002_bib19","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/ac1e76","article-title":"Perichondrium-inspired permeable nanofibrous tube well promoting differentiation of hiPSC-derived pellet toward hyaline-like cartilage pellet","volume":"13","author":"Lee","year":"2021","journal-title":"Biofabrication"},{"key":"10.1016\/j.stem.2026.03.002_bib20","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-020-02045-3","article-title":"Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo","volume":"12","author":"Futrega","year":"2021","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.stem.2026.03.002_bib21","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s13770-019-00231-w","article-title":"Rapid cartilage regeneration of spheroids composed of human nasal septum-derived chondrocyte in rat osteochondral defect model","volume":"17","author":"Jeon","year":"2020","journal-title":"Tissue Eng. Regen. Med."},{"key":"10.1016\/j.stem.2026.03.002_bib22","article-title":"Intestine-targeted controlled hydrogen-releasing MgH2 microcapsules for improving the mitochondrial metabolism of inflammatory bowel disease","volume":"34","author":"Liu","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.stem.2026.03.002_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2023.122230","article-title":"Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery","volume":"301","author":"Zhao","year":"2023","journal-title":"Biomaterials"},{"key":"10.1016\/j.stem.2026.03.002_bib24","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1007\/s12274-022-4860-y","article-title":"Fe-porphyrin: a redox-related biosensor of hydrogen molecule","volume":"16","author":"Jin","year":"2023","journal-title":"Nano Res."},{"key":"10.1016\/j.stem.2026.03.002_bib25","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S1063-4584(03)00150-X","article-title":"The role of reactive oxygen species in homeostasis and degradation of cartilage","volume":"11","author":"Henrotin","year":"2003","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.stem.2026.03.002_bib26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.freeradbiomed.2018.08.038","article-title":"Reactive oxygen species, aging and articular cartilage homeostasis","volume":"132","author":"Bolduc","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.stem.2026.03.002_bib27","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.bbrc.2008.06.011","article-title":"Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes","volume":"373","author":"Heywood","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.stem.2026.03.002_bib28","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1080\/10715769900300431","article-title":"Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants","volume":"30","author":"Tiku","year":"1999","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.stem.2026.03.002_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.149733","article-title":"Mechanisms of chondrocyte regulated cell death in osteoarthritis: Focus on ROS-triggered ferroptosis, parthanatos, and oxeiptosis","volume":"705","author":"Fan","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.stem.2026.03.002_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-023-43618-z","article-title":"Q. Local H2 release remodels senescence microenvironment for improved repair of injured bone","volume":"14","author":"Chen","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.stem.2026.03.002_bib31","article-title":"Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing","volume":"13","author":"Chen","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.stem.2026.03.002_bib32","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abq0959","article-title":"NIR-photocatalytic regulation of arthritic synovial microenvironment","volume":"8","author":"Zhao","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.stem.2026.03.002_bib33","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/nm1577","article-title":"Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals","volume":"13","author":"Ohsawa","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.stem.2026.03.002_bib34","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.bbrc.2010.06.009","article-title":"Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials","volume":"397","author":"Kawasaki","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.stem.2026.03.002_bib35","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10561-019-09758-7","article-title":"Storage solution containing hydrogen improves the preservation effect of osteochondral allograft","volume":"20","author":"Han","year":"2019","journal-title":"Cell Tissue Bank."},{"key":"10.1016\/j.stem.2026.03.002_bib36","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202114594","article-title":"An activity-based ratiometric fluorescent probe for in vivo real-time imaging of hydrogen molecules","volume":"61","author":"Gong","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.stem.2026.03.002_bib37","doi-asserted-by":"crossref","DOI":"10.1093\/nsr\/nwad063","article-title":"Sonocatalytic hydrogen\/hole-combined therapy for anti-biofilm and infected diabetic wound healing","volume":"10","author":"Xu","year":"2023","journal-title":"Natl. Sci. Rev."},{"key":"10.1016\/j.stem.2026.03.002_bib38","article-title":"Ultrasound-driven piezoelectrocatalytic immunoactivation of deep tumor","volume":"10","author":"Wu","year":"2023","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.stem.2026.03.002_bib39","article-title":"Local sustained H2 release assisted stem cell transplantation for enhanced osteoarthritic cartilage regeneration","volume":"2","author":"Chen","year":"2025","journal-title":"Cell Biomater."},{"key":"10.1016\/j.stem.2026.03.002_bib40","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.actbio.2022.12.056","article-title":"Injectable spontaneous hydrogen-releasing hydrogel for long-lasting alleviation of osteoarthritis","volume":"158","author":"Zhang","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.stem.2026.03.002_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202201705","article-title":"Two-dimensional Mg2Si nanosheet-enabled sustained hydrogen generation for improved repair and regeneration of deeply-burned skin","volume":"12","author":"Zhu","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.stem.2026.03.002_bib42","article-title":"A sustained H2\/fluorouracil-releasing suppository for high efficacy and low-toxicity hydrogenochemotherapy of colon cancer","volume":"14","author":"Chen","year":"2025","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.stem.2026.03.002_bib43","doi-asserted-by":"crossref","first-page":"2772","DOI":"10.1021\/ja808426h","article-title":"TiO2\/TiSi2 heterostructures for high-efficiency photoelectrochemical H2O splitting","volume":"131","author":"Lin","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.stem.2026.03.002_bib44","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1039\/c2cp44270a","article-title":"RuO2\/TiSi2\/graphene composite for enhanced photocatalytic hydrogen generation under visible light irradiation","volume":"15","author":"Mou","year":"2013","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.stem.2026.03.002_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/catal9030299","article-title":"One-Step synthesis of MoS2\/TiSi2 via an in situ photo-assisted reduction method for enhanced photocatalytic H2 evolution under simulated sunlight illumination","volume":"9","author":"Zhang","year":"2019","journal-title":"Catalysts"},{"key":"10.1016\/j.stem.2026.03.002_bib46","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2016.0851","article-title":"Measurement of oxygen tension within mesenchymal stem cell spheroids","volume":"14","author":"Murphy","year":"2017","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.stem.2026.03.002_bib47","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00441-014-1830-z","article-title":"Human mesenchymal stem cell spheroids in fibrin hydrogels exhibit improved cell survival and potential for bone healing","volume":"357","author":"Murphy","year":"2014","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.stem.2026.03.002_bib48","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nprot.2016.037","article-title":"Functionalization, preparation and use of cell-laden gelatin methacryloyl\u2013based hydrogels as modular tissue culture platforms","volume":"11","author":"Loessner","year":"2016","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.stem.2026.03.002_bib49","article-title":"Acid-responsive H2-releasing 2D MgB2 nanosheet for therapeutic synergy and side effect attenuation of gastric cancer chemotherapy","volume":"8","author":"Fan","year":"2019","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.stem.2026.03.002_bib50","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/s41584-023-00966-w","article-title":"Matrix metalloproteinases in arthritis: towards precision medicine","volume":"19","author":"Grillet","year":"2023","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.stem.2026.03.002_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116786","article-title":"The role of matrix metalloproteinases in osteoarthritis pathogenesis: an updated review","volume":"234","author":"Mehana","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.stem.2026.03.002_bib52","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaz4499","article-title":"Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects","volume":"13","author":"Acevedo Rua","year":"2021","journal-title":"Sci. Transl. Med."}],"container-title":["Cell Stem Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934590926001128?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934590926001128?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:23:36Z","timestamp":1778833416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934590926001128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S1934590926001128"],"URL":"https:\/\/doi.org\/10.1016\/j.stem.2026.03.002","relation":{},"ISSN":["1934-5909"],"issn-type":[{"value":"1934-5909","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preservation of chondrocyte microspheroids by local sustained hydrogen supply improves osteoarthritic cartilage repair","name":"articletitle","label":"Article Title"},{"value":"Cell Stem Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.stem.2026.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}