{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:04:06Z","timestamp":1790168646261,"version":"4.1.0"},"reference-count":9,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Stem Cell"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.stem.2026.07.005","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T15:11:12Z","timestamp":1786029072000},"page":"1246-1248","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The price of plasticity: Losing colon identity to gain metastatic potential"],"prefix":"10.1016","volume":"33","author":[{"given":"Bianca","family":"B\u0103loiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4189-5213","authenticated-orcid":false,"given":"Hugo J.G.","family":"Snippert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.stem.2026.07.005_bib1","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/j.stem.2026.05.013","article-title":"Lineage plasticity driven by GATA6 loss fuels colorectal cancer metastasis","volume":"33","author":"Goto","year":"2026","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stem.2026.07.005_bib2","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/s41586-024-07135-3","article-title":"SOX17 enables immune evasion of early colorectal adenomas and cancers","volume":"627","author":"Goto","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.stem.2026.07.005_bib3","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/s41586-025-09125-5","article-title":"Loss of colonic fidelity enables multilineage plasticity and metastasis","volume":"644","author":"Cammareri","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.stem.2026.07.005_bib4","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/s41586-024-08150-0","article-title":"Progressive plasticity during colorectal cancer metastasis","volume":"637","author":"Moorman","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.stem.2026.07.005_bib5","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/s41588-024-02058-1","article-title":"Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer","volume":"57","author":"Mzoughi","year":"2025","journal-title":"Nat. Genet."},{"key":"10.1016\/j.stem.2026.07.005_bib6","article-title":"Phenotypic heterogeneity and plasticity in colorectal cancer metastasis","volume":"5","author":"Ogden","year":"2025","journal-title":"Cell Genom."},{"key":"10.1016\/j.stem.2026.07.005_bib7","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/s41586-026-10344-7","article-title":"Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers","volume":"654","author":"Buissant des Amorie","year":"2026","journal-title":"Nature"},{"key":"10.1016\/j.stem.2026.07.005_bib8","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/s41586-022-05402-9","article-title":"Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells","volume":"611","author":"Ca\u00f1ellas-Socias","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.stem.2026.07.005_bib9","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1158\/0008-5472.CAN-21-0933","article-title":"Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage","volume":"82","author":"Heinz","year":"2022","journal-title":"Cancer Res."}],"container-title":["Cell Stem Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934590926002651?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934590926002651?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T12:20:26Z","timestamp":1790166026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934590926002651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1934590926002651"],"URL":"https:\/\/doi.org\/10.1016\/j.stem.2026.07.005","relation":{},"ISSN":["1934-5909"],"issn-type":[{"value":"1934-5909","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The price of plasticity: Losing colon identity to gain metastatic potential","name":"articletitle","label":"Article Title"},{"value":"Cell Stem Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.stem.2026.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.stem.2026.05.013","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}