{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:47:06Z","timestamp":1777898826876,"version":"3.51.4"},"reference-count":63,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DK10381"],"award-info":[{"award-number":["R01 DK10381"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA68485-19"],"award-info":[{"award-number":["P30 CA68485-19"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2444112"],"award-info":[{"award-number":["2444112"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["193797963"],"award-info":[{"award-number":["193797963"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["P30 DK058404"],"award-info":[{"award-number":["P30 DK058404"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01 DK128190"],"award-info":[{"award-number":["R01 DK128190"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["RC2 DK118640"],"award-info":[{"award-number":["RC2 DK118640"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Reports"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.stemcr.2026.102820","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T16:07:05Z","timestamp":1771517225000},"page":"102820","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Myosin VB is critical for progenitor cell identity and function in the intestine"],"prefix":"10.1016","volume":"21","author":[{"given":"Andreanna","family":"Burman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica E.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Momoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca","family":"Adeniran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken S.","family":"Lau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda C.","family":"Samuelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell D.","family":"Shub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph T.","family":"Roland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5395-0497","authenticated-orcid":false,"given":"Izumi","family":"Kaji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.stemcr.2026.102820_bib1","doi-asserted-by":"crossref","first-page":"C475","DOI":"10.1152\/ajpcell.00180.2008","article-title":"Revised immunolocalization of the Na+-D-glucose cotransporter SGLT1 in rat organs with an improved antibody","volume":"295","author":"Balen","year":"2008","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.stemcr.2026.102820_bib2","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1101\/gad.1674008","article-title":"The intestinal stem cell","volume":"22","author":"Barker","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.stemcr.2026.102820_bib3","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.stemcr.2020.05.010","article-title":"Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition","volume":"15","author":"Bohin","year":"2020","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.stemcr.2026.102820_bib4","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.jcmgh.2020.05.013","article-title":"Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury","volume":"10","author":"Bohin","year":"2020","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.jcmgh.2022.04.015","article-title":"Altered MYO5B Function Underlies Microvillus Inclusion Disease: Opportunities for Intervention at a Cellular Level","volume":"14","author":"Bowman","year":"2022","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2025.108328","article-title":"Microvillus inclusion disease-causing MYO5B point mutations exert differential effects on motor function","volume":"301","author":"Bowman","year":"2025","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.stemcr.2026.102820_bib7","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.jcmgh.2022.12.015","article-title":"Modeling of a Novel Patient-Based MYO5B Point Mutation Reveals Insights Into MVID Pathogenesis","volume":"15","author":"Burman","year":"2023","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib8","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1016\/j.cub.2007.10.039","article-title":"YAP1 increases organ size and expands undifferentiated progenitor cells","volume":"17","author":"Camargo","year":"2007","journal-title":"Curr. Biol."},{"key":"10.1016\/j.stemcr.2026.102820_bib9","doi-asserted-by":"crossref","first-page":"5279","DOI":"10.1038\/s41388-022-02508-2","article-title":"Myosin Vb as a tumor suppressor gene in intestinal cancer","volume":"41","author":"Carton-Garcia","year":"2022","journal-title":"Oncogene"},{"key":"10.1016\/j.stemcr.2026.102820_bib10","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1053\/j.gastro.2019.11.031","article-title":"HNF4 Regulates Fatty Acid Oxidation and Is Required for Renewal of Intestinal Stem Cells in Mice","volume":"158","author":"Chen","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib11","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1056\/NEJM198903093201006","article-title":"Microvillus inclusion disease: an inherited defect of brush-border assembly and differentiation","volume":"320","author":"Cutz","year":"1989","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.stemcr.2026.102820_bib12","doi-asserted-by":"crossref","first-page":"4099","DOI":"10.1158\/0008-5472.CAN-18-4075","article-title":"Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling","volume":"79","author":"D'Agostino","year":"2019","journal-title":"Cancer Res."},{"key":"10.1016\/j.stemcr.2026.102820_bib13","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/0016-5085(78)90458-4","article-title":"Familial enteropathy: a syndrome of protracted diarrhea from birth, failure to thrive, and hypoplastic villus atrophy","volume":"75","author":"Davidson","year":"1978","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.894737","article-title":"The Hippo-YAP\/TAZ Signaling Pathway in Intestinal Self-Renewal and Regeneration After Injury","volume":"10","author":"Deng","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.stemcr.2026.102820_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmgh.2025.101537","article-title":"The molecular motor Myosin 5B and its folding chaperone UNC45A are decreased in colorectal cancer","volume":"19","author":"Dooley","year":"2025","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib16","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1053\/j.gastro.2020.02.034","article-title":"Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-Lined Inclusions and Alterations in Sodium Transporters","volume":"158","author":"Engevik","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib17","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1053\/j.gastro.2018.08.025","article-title":"Loss of MYO5B Leads to Reductions in Na(+) Absorption With Maintenance of CFTR-Dependent Cl(-) Secretion in Enterocytes","volume":"155","author":"Engevik","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib18","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1002\/ajmg.a.32605","article-title":"Navajo microvillous inclusion disease is due to a mutation in MYO5B","volume":"146a","author":"Erickson","year":"2008","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.stemcr.2026.102820_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.100848","article-title":"RAB11A-mediated YAP localization to adherens and tight junctions is essential for colonic epithelial integrity","volume":"297","author":"Goswami","year":"2021","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.stemcr.2026.102820_bib20","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/nature15382","article-title":"Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer","volume":"526","author":"Gregorieff","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.stemcr.2026.102820_bib21","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/S0046-8177(00)80011-8","article-title":"Enterocyte apoptosis and proliferation are increased in microvillous inclusion disease (familial microvillous atrophy)","volume":"31","author":"Groisman","year":"2000","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.stemcr.2026.102820_bib22","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nature24489","article-title":"A single-cell survey of the small intestinal epithelium","volume":"551","author":"Haber","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.stemcr.2026.102820_bib23","doi-asserted-by":"crossref","first-page":"26533","DOI":"10.1074\/jbc.M111.265322","article-title":"BCL-2 modifying factor (BMF) is a central regulator of anoikis in human intestinal epithelial cells","volume":"286","author":"Hausmann","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.stemcr.2026.102820_bib24","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.cell.2005.06.007","article-title":"The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP","volume":"122","author":"Huang","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib25","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/ncb3084","article-title":"Dual role of YAP and TAZ in renewal of the intestinal epithelium","volume":"17","author":"Imajo","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.stemcr.2026.102820_bib26","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1016\/j.jcmgh.2022.08.007","article-title":"Limitations to Understanding Intestinal Stem Cell Activity via Cre-Lox-Based Lineage Tracing","volume":"14","author":"Johnson","year":"2022","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib27","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202256240","article-title":"RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells","volume":"24","author":"Joseph","year":"2023","journal-title":"EMBO Rep."},{"key":"10.1016\/j.stemcr.2026.102820_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2025.1498902","article-title":"Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells","volume":"13","author":"Joseph","year":"2025","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.stemcr.2026.102820_bib29","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.150416","article-title":"Cell differentiation is disrupted by MYO5B loss through Wnt\/Notch imbalance","volume":"6","author":"Kaji","year":"2021","journal-title":"JCI Insight"},{"key":"10.1016\/j.stemcr.2026.102820_bib30","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1053\/j.gastro.2020.06.008","article-title":"Lysophosphatidic Acid Increases Maturation of Brush Borders and SGLT1 Activity in MYO5B-deficient Mice, a Model of Microvillus Inclusion Disease","volume":"159","author":"Kaji","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib31","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202310118","article-title":"Modeling the cell biology of monogenetic intestinal epithelial disorders","volume":"223","author":"Kaji","year":"2024","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.stemcr.2026.102820_bib32","doi-asserted-by":"crossref","first-page":"G142","DOI":"10.1152\/ajpgi.00041.2016","article-title":"Identification of intestinal ion transport defects in microvillus inclusion disease","volume":"311","author":"Kravtsov","year":"2016","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.stemcr.2026.102820_bib33","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1074\/jbc.M113.516351","article-title":"A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases","volume":"289","author":"Landry","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.stemcr.2026.102820_bib34","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1091\/mbc.12.6.1843","article-title":"Myosin vb is associated with plasma membrane recycling systems","volume":"12","author":"Lapierre","year":"2001","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib35","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.049692","article-title":"Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth","volume":"16","author":"Lemmetyinen","year":"2023","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.stemcr.2026.102820_bib36","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.stem.2018.04.001","article-title":"Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging","volume":"22","author":"Mihaylova","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib37","doi-asserted-by":"crossref","first-page":"G877","DOI":"10.1152\/ajpgi.00091.2024","article-title":"Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation","volume":"327","author":"Momoh","year":"2024","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.stemcr.2026.102820_bib38","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1038\/ng.225","article-title":"MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity","volume":"40","author":"Muller","year":"2008","journal-title":"Nat. Genet."},{"key":"10.1016\/j.stemcr.2026.102820_bib39","doi-asserted-by":"crossref","first-page":"3079","DOI":"10.1038\/emboj.2012.166","article-title":"The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers","volume":"31","author":"Munoz","year":"2012","journal-title":"EMBO J."},{"key":"10.1016\/j.stemcr.2026.102820_bib40","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.celrep.2013.09.005","article-title":"Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium","volume":"5","author":"Mustata","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.stemcr.2026.102820_bib41","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1113\/EP091040","article-title":"Active glucose transport varies by small intestinal region and oestrous cycle stage in mice","volume":"108","author":"Overduin","year":"2023","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.stemcr.2026.102820_bib42","first-page":"34","article-title":"Periodic acid-Schiff staining abnormality in microvillous atrophy: photometric and ultrastructural studies","volume":"30","author":"Phillips","year":"2000","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.stemcr.2026.102820_bib43","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adf9460","article-title":"Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation","volume":"9","author":"Pikkupeura","year":"2023","journal-title":"Sci. Adv."},{"key":"10.1016\/j.stemcr.2026.102820_bib44","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.cell.2012.02.042","article-title":"The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor","volume":"149","author":"Powell","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib45","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1126\/science.1062257","article-title":"Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis","volume":"293","author":"Puthalakath","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.stemcr.2026.102820_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmgh.2024.101443","article-title":"Paneth Cells: Dispensable yet Irreplaceable for the Intestinal Stem Cell Niche","volume":"19","author":"Quintero","year":"2025","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib47","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1750-1172-1-22","article-title":"Microvillous inclusion disease (microvillous atrophy)","volume":"1","author":"Ruemmele","year":"2006","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.stemcr.2026.102820_bib48","doi-asserted-by":"crossref","first-page":"4827","DOI":"10.1113\/JP271931","article-title":"The regulatory niche of intestinal stem cells","volume":"594","author":"Sailaja","year":"2016","journal-title":"J. Physiol."},{"key":"10.1016\/j.stemcr.2026.102820_bib49","doi-asserted-by":"crossref","first-page":"12408","DOI":"10.1073\/pnas.1516672112","article-title":"An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking","volume":"112","author":"Schneeberger","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.stemcr.2026.102820_bib50","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.stemcr.2014.05.018","article-title":"Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus","volume":"3","author":"Schuijers","year":"2014","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.stemcr.2026.102820_bib51","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41575-024-00980-7","article-title":"Dietary and metabolic effects on intestinal stem cells in health and disease","volume":"22","author":"Shay","year":"2025","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib52","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.stem.2019.08.017","article-title":"PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism","volume":"25","author":"Stine","year":"2019","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108633","article-title":"A constant pool of Lgr5(+) intestinal stem cells is required for intestinal homeostasis","volume":"34","author":"Tan","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.stemcr.2026.102820_bib54","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1053\/j.gastro.2018.03.067","article-title":"Advances in Evaluation of Chronic Diarrhea in Infants","volume":"154","author":"Thiagarajah","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib55","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nature10408","article-title":"A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable","volume":"478","author":"Tian","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.stemcr.2026.102820_bib56","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008803","article-title":"MYO5B mutations in pheochromocytoma\/paraganglioma promote cancer progression","volume":"16","author":"Tomi\u0107","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.stemcr.2026.102820_bib57","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1053\/j.gastro.2009.05.035","article-title":"OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells","volume":"137","author":"van der Flier","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.stemcr.2026.102820_bib58","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.stem.2024.05.009","article-title":"Activation of fetal-like molecular programs during regeneration in the intestine and beyond","volume":"31","author":"Viragova","year":"2024","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib59","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.tcb.2021.02.001","article-title":"Metabolic Regulation of Intestinal Stem Cell Homeostasis","volume":"31","author":"Wang","year":"2021","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.stemcr.2026.102820_bib60","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jcmgh.2015.11.009","article-title":"Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum","volume":"2","author":"Weis","year":"2016","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.stemcr.2026.102820_bib61","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.stem.2017.11.001","article-title":"YAP\/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration","volume":"22","author":"Yui","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.stemcr.2026.102820_bib62","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1101\/gad.1664408","article-title":"TEAD mediates YAP-dependent gene induction and growth control","volume":"22","author":"Zhao","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.stemcr.2026.102820_bib63","doi-asserted-by":"crossref","first-page":"E1312","DOI":"10.1073\/pnas.1110428108","article-title":"Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance","volume":"108","author":"Zhou","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"}],"updated-by":[{"DOI":"10.1016\/j.stemcr.2026.102862","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000}},{"DOI":"10.1016\/j.stemcr.2026.102862","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000}}],"container-title":["Stem Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213671126000317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213671126000317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:42:21Z","timestamp":1777628541000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213671126000317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":63,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2213671126000317"],"URL":"https:\/\/doi.org\/10.1016\/j.stemcr.2026.102820","relation":{},"ISSN":["2213-6711"],"issn-type":[{"value":"2213-6711","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myosin VB is critical for progenitor cell identity and function in the intestine","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.stemcr.2026.102820","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of International Society for Stem Cell Research.","name":"copyright","label":"Copyright"}],"article-number":"102820"}}