{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:42:33Z","timestamp":1792446153632,"version":"4.5.0"},"reference-count":141,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1016\/j.steroids.2007.10.013","type":"journal-article","created":{"date-parts":[[2007,11,13]],"date-time":"2007-11-13T07:22:34Z","timestamp":1194938554000},"page":"233-244","source":"Crossref","is-referenced-by-count":281,"title":["The role of estrogens and estrogen receptors in normal prostate growth and disease"],"prefix":"10.1016","volume":"73","author":[{"given":"Gail S.","family":"Prins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth S.","family":"Korach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.steroids.2007.10.013_bib1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/pros.2990210407","article-title":"Immunohistochemical evidence of the existence and localization of aromatase in human prostatic tissues","volume":"21","author":"Matzkin","year":"1992","journal-title":"Prostate"},{"key":"10.1016\/j.steroids.2007.10.013_bib2","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1677\/erc.0.0100187","article-title":"Estrogens and prostate cancer","volume":"10","author":"Risbridger","year":"2003","journal-title":"Endocr Relat Cancer"},{"key":"10.1016\/j.steroids.2007.10.013_bib3","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1530\/acta.0.1120447","article-title":"Hormone levels in the fetal and neonatal prostate","volume":"112","author":"Zondek","year":"1986","journal-title":"Acta Endocr"},{"key":"10.1016\/j.steroids.2007.10.013_bib4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/pros.2990170104","article-title":"Morphological and immunohistochemical investigations of the utriculus prostaticus from the fetal period up to adulthood","volume":"17","author":"Wernet","year":"1990","journal-title":"Prostate"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib5","first-page":"186","article-title":"Sex steroid imprinting of the immature prostate","volume":"16","author":"Rajfer","year":"1978","journal-title":"Invest Urol"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib6","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/bjc.1988.46","article-title":"The early in utero oestrogen and testosterone environment of blacks and whites: potential effects on male offspring","volume":"57","author":"Henderson","year":"1988","journal-title":"Br J Cancer"},{"key":"10.1016\/j.steroids.2007.10.013_bib7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jsbmb.2004.10.002","article-title":"The epidemiology of sex steroid hormones and their signaling and metabolic pathways in the etiology of prostate cancer","volume":"92","author":"Platz","year":"2004","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib8","first-page":"221","article-title":"Duration of gestation and prostate cancer risk in offspring","volume":"9","author":"Ekbom","year":"2000","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.steroids.2007.10.013_bib9","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1136\/bmj.313.7053.337","article-title":"Perinatal characteristics in relation to incidence of and mortality from prostate cancer","volume":"313","author":"Ekbom","year":"1996","journal-title":"Br Med J"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib10","first-page":"537","article-title":"Effects of prenatal maternal estrogen on the male urogenital system","volume":"56","author":"Driscoll","year":"1980","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.steroids.2007.10.013_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000147709","article-title":"Temporal and spatial factors in diethylstilbestrol-induced squamous metaplasia in the developing human prostate. II. Persistent changes after removal of diethylstilbestrol","volume":"153","author":"Yonemura","year":"1995","journal-title":"Acta Anatom"},{"issue":"10","key":"10.1016\/j.steroids.2007.10.013_bib12","doi-asserted-by":"crossref","first-page":"778","DOI":"10.7326\/0003-4819-122-10-199505150-00008","article-title":"Diethylstilbestrol revisited: a review of the long-term health effects","volume":"122","author":"Giusti","year":"1995","journal-title":"Ann Int Med"},{"key":"10.1016\/j.steroids.2007.10.013_bib13","first-page":"235","article-title":"Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals","volume":"vol. 84","author":"Arai","year":"1983"},{"key":"10.1016\/j.steroids.2007.10.013_bib14","series-title":"Prostate: basic and clinical aspects","first-page":"247","article-title":"Developmental estrogenization of the prostate gland","author":"Prins","year":"1997"},{"key":"10.1016\/j.steroids.2007.10.013_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1386.009","article-title":"The role of estrogens in normal and abnormal development of the prostate gland","volume":"1089","author":"Prins","year":"2006","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib16","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1210\/er.22.3.319","article-title":"Environmental signaling: what embryos and evolution teach us about endocrine disrupting chemicals","volume":"22","author":"McLachlan","year":"2001","journal-title":"Endocr Rev"},{"issue":"11","key":"10.1016\/j.steroids.2007.10.013_bib17","doi-asserted-by":"crossref","first-page":"5624","DOI":"10.1158\/0008-5472.CAN-06-0516","article-title":"Developmental exposure estradiol and bisphenol A (BPA) increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodisesterase type 4 variant (PDE4D4) in the rat prostate","volume":"66","author":"Ho","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib18","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1210\/er.2004-0013","article-title":"The decline of androgen levels in elderly men and its clinical and therapeutic implications","volume":"26","author":"Kaufman","year":"2005","journal-title":"Endocrin Rev"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib19","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1080\/713604678","article-title":"Estradiol in elderly men","volume":"5","author":"Vermeulen","year":"2002","journal-title":"Aging Male"},{"key":"10.1016\/j.steroids.2007.10.013_bib20","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/jcb.10759","article-title":"Estrogens and antiestrogens: key mediators of prostate carcinogenesis and new therapeutic candidates","volume":"91","author":"Ho","year":"2004","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.steroids.2007.10.013_bib21","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/pros.20327","article-title":"Effect of increasing ratio of estrogen:androgen on proliferation of normal and human prostate stromal and epithelial cells and the malignant cell line LNCaP","volume":"66","author":"King","year":"2006","journal-title":"Prostate"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/j.1939-4640.1994.tb00409.x","article-title":"Effects of estrogen on the prostate","volume":"15","author":"Thomas","year":"1994","journal-title":"J Androl"},{"key":"10.1016\/j.steroids.2007.10.013_bib23","series-title":"Non-reproductive actions of sex steroids","first-page":"269","article-title":"Human prostate cancer: a direct role for oestrogens","author":"Castagnetta","year":"1995"},{"key":"10.1016\/j.steroids.2007.10.013_bib24","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/aja.1000600105","article-title":"Normal development of the prostate and seminal vesicles of the rat with a study of experimental postnatal modifications","volume":"60","author":"Price","year":"1936","journal-title":"Am J Anat"},{"issue":"13","key":"10.1016\/j.steroids.2007.10.013_bib25","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1093\/jnci\/80.13.1045","article-title":"Biochemical alterations in sex hormone-induced hyperplasia and dysplasia of the dorsolateral prostates of Noble rats","volume":"80","author":"Leav","year":"1988","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib26","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0094-0143(21)00960-5","article-title":"Clinical and experimental studies of benign prostatic hyperplasia","volume":"17","author":"Coffey","year":"1990","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.steroids.2007.10.013_bib27","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1172\/JCI109532","article-title":"Comparison of spontaneous and experimentally induced canine prostatic hyperplasia","volume":"64","author":"DeKlerk","year":"1979","journal-title":"J Clin Invest"},{"key":"10.1016\/j.steroids.2007.10.013_bib28","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1530\/acta.0.0960422","article-title":"Stroma of human benign prostatic hyperplasia: preferential tissue for androgen metabolism and oestrogen binding","volume":"96","author":"Krieg","year":"1981","journal-title":"Acta Endocr"},{"issue":"6","key":"10.1016\/j.steroids.2007.10.013_bib29","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/j.1939-4640.1981.tb00633.x","article-title":"Effect of estradiol on the rat prostate in the presence and absence of testosterone and pituitary","volume":"2","author":"Lee","year":"1981","journal-title":"J Androl"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib30","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1210\/en.2002-0038","article-title":"The role of prolactin in the prostatic inflammatory response to neonatal estrogen","volume":"144","author":"Gilleran","year":"2003","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.steroids.2007.10.013_bib31","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1093\/carcin\/18.8.1505","article-title":"Suppression of testosterone and estradiol-17beta-induced dysplasia in the dorsolateral prostate of Noble rats by bromocriptine","volume":"18","author":"Lane","year":"1997","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.steroids.2007.10.013_bib32","first-page":"293","article-title":"Studies on prostatic cancer. I. The effect of castration, of estrogen, and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate","volume":"1","author":"Huggins","year":"1941","journal-title":"Cancer Res"},{"issue":"6","key":"10.1016\/j.steroids.2007.10.013_bib33","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1210\/en.130.6.3703","article-title":"Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression","volume":"130","author":"Prins","year":"1992","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib34","first-page":"5199","article-title":"Hormone regulation of human prostate in organ culture","volume":"53","author":"Nevalainen","year":"1993","journal-title":"Cancer Res"},{"issue":"9","key":"10.1016\/j.steroids.2007.10.013_bib35","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.1210\/en.141.9.3471","article-title":"Evidence that estrogens directly alter androgen-regulated prostate development","volume":"141","author":"Jarred","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/dna.1987.6.1","article-title":"The P450 gene superfamily: recommended nomenclature","volume":"6","author":"Nebert","year":"1987","journal-title":"DNA"},{"key":"10.1016\/j.steroids.2007.10.013_bib37","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0092-8674(00)80726-6","article-title":"A unified nomenclature system for the nuclear receptor superfamily","volume":"97","author":"Committee NRN","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.steroids.2007.10.013_bib38","doi-asserted-by":"crossref","first-page":"7889","DOI":"10.1073\/pnas.82.23.7889","article-title":"Cloning of the human estrogen receptor cDNA","volume":"82","author":"Walter","year":"1985","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.steroids.2007.10.013_bib39","series-title":"The nuclear receptor factsbook","author":"Laudet","year":"2002"},{"key":"10.1016\/j.steroids.2007.10.013_bib40","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1210\/mend-1-10-735","article-title":"Structural organization and expression of the mouse estrogen receptor","volume":"1","author":"White","year":"1987","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.steroids.2007.10.013_bib41","first-page":"369","article-title":"Steroid receptor variants and their potential role in cancer","volume":"5","author":"Miksicek","year":"1994","journal-title":"Sem Cancer Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib42","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/humu.1380060202","article-title":"Mutations in the estrogen receptor gene","volume":"6","author":"Sluyser","year":"1995","journal-title":"Hum Mutat"},{"key":"10.1016\/j.steroids.2007.10.013_bib43","doi-asserted-by":"crossref","first-page":"5925","DOI":"10.1073\/pnas.93.12.5925","article-title":"Cloning of a novel estrogen receptor expressed in rat prostate and ovary","volume":"93","author":"Kuiper","year":"1996","journal-title":"Proc Natl Acac Sci USA"},{"key":"10.1016\/j.steroids.2007.10.013_bib44","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0014-5793(96)00782-X","article-title":"ER B: identification and characterization of a novel human estrogen receptor","volume":"392","author":"Mosselman","year":"1996","journal-title":"FEBS"},{"issue":"35","key":"10.1016\/j.steroids.2007.10.013_bib45","doi-asserted-by":"crossref","first-page":"13162","DOI":"10.1073\/pnas.0605676103","article-title":"Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling","volume":"103","author":"Leung","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.steroids.2007.10.013_bib46","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/0092-8674(95)90199-X","article-title":"The nuclear receptor superfamily: the second decade","volume":"83","author":"Mangelsdorf","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.steroids.2007.10.013_bib47","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1152\/physrev.2001.81.3.1269","article-title":"Nuclear hormone receptors and gene expression","volume":"81","author":"Aranda","year":"2001","journal-title":"Physiol Rev"},{"key":"10.1016\/j.steroids.2007.10.013_bib48","doi-asserted-by":"crossref","first-page":"7076","DOI":"10.1074\/jbc.M108255200","article-title":"Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways","volume":"277","author":"Ueda","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.steroids.2007.10.013_bib49","first-page":"163","article-title":"Estrogen receptors: selective ligands, partners, and distinctive pharmacology","volume":"55","author":"Katzenellenbogen","year":"2000","journal-title":"Recent Prog Horm Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib50","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1124\/mol.58.3.584","article-title":"Functional differences between the amino-terminal domains of estrogen receptors alpha and beta","volume":"58","author":"Delaunay","year":"2000","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.steroids.2007.10.013_bib51","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1006\/bbrc.1997.6915","article-title":"Agonist effect of tamoxifen is dependent on cell type, ERE-promoter context, and estrogen receptor subtype: functional difference between estrogen receptors \u03b1 and \u03b2","volume":"236","author":"Watanabe","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.steroids.2007.10.013_bib52","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0960-0760(99)00055-2","article-title":"A comparison of transcriptional activation by ER alpha and ER beta","volume":"69","author":"Cowley","year":"1999","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib53","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0014-5793(97)00413-4","article-title":"The novel estrogen receptor-b subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens","volume":"410","author":"Kuiper","year":"1997","journal-title":"FEBS Lett"},{"key":"10.1016\/j.steroids.2007.10.013_bib54","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1210\/me.2002-0406","article-title":"Domains of estrogen receptor alpha (ERalpha) required for ERalpha\/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells","volume":"17","author":"Kim","year":"2003","journal-title":"Mol Endocrinol"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib55","article-title":"Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism","volume":"9","author":"Shiau","year":"2002","journal-title":"Nat Struct Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib56","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1002\/(SICI)1097-4644(19991215)75:4<640::AID-JCB10>3.0.CO;2-8","article-title":"Regulation of estrogen receptor-alpha gene expression by 1,25-dihydroxyvitamin D in MCF-7 cells","volume":"75","author":"Stoica","year":"1999","journal-title":"J Cell Biochem"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib57","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1210\/en.138.3.863","article-title":"Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors \u03b1 and B","volume":"138","author":"Kuiper","year":"1997","journal-title":"Endocrinology"},{"issue":"10","key":"10.1016\/j.steroids.2007.10.013_bib58","doi-asserted-by":"crossref","first-page":"4252","DOI":"10.1210\/en.139.10.4252","article-title":"Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor \u03b2","volume":"139","author":"Kuiper","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib59","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0039-128X(01)00194-5","article-title":"The ligand binding profiles of estrogen receptors alpha and beta are species dependent","volume":"67","author":"Harris","year":"2002","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2007.10.013_bib60","doi-asserted-by":"crossref","first-page":"4172","DOI":"10.1210\/en.2002-220403","article-title":"Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand","volume":"143","author":"Harris","year":"2002","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib61","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1210\/me.9.7.814","article-title":"The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists","volume":"9","author":"Montano","year":"1995","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.steroids.2007.10.013_bib62","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1210\/me.2006-0203","article-title":"Identification of Regions within the F domain of the human estrogen receptor {alpha} that are important for modulating transactivation and protein\u2013protein interactions","volume":"21","author":"Koide","year":"2007","journal-title":"Mol Endocrinol"},{"issue":"3\u20135","key":"10.1016\/j.steroids.2007.10.013_bib63","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jsbmb.2007.03.002","article-title":"Oestrogen receptors pathways to oestrogen responsive elements: The transactivation function-1 acts as the keystone of oestrogen receptor (ER)alpha-mediated transcriptional repression of ERalpha","volume":"104","author":"Gougeleta","year":"2007","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib64","doi-asserted-by":"crossref","first-page":"4658","DOI":"10.1073\/pnas.89.10.4658","article-title":"Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor","volume":"89","author":"Ignar-Trowbridge","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.steroids.2007.10.013_bib65","doi-asserted-by":"crossref","first-page":"D1379","DOI":"10.2741\/Coleman","article-title":"Intracellular signaling pathways: nongenomic actions of estrogens and ligand-independent activation of estrogen receptors","volume":"6","author":"Coleman","year":"2001","journal-title":"Front Biosci"},{"key":"10.1016\/j.steroids.2007.10.013_bib66","doi-asserted-by":"crossref","first-page":"8531","DOI":"10.1074\/jbc.M109592200","article-title":"Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1\/estrogen receptor cross-talk","volume":"277","author":"Klotz","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.steroids.2007.10.013_bib67","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.1210\/en.141.9.3430","article-title":"Activation of a uterine insulin-like growth factor I signaling pathway by clinical and environmental estrogens: requirement of estrogen receptor-alpha","volume":"141","author":"Klotz","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0079-6603(04)77001-4","article-title":"Nuclear receptor-mediated transactivation through interaction with Sp proteins","volume":"77","author":"Safe","year":"2004","journal-title":"Prog Nucleic Acid Res Mol Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib69","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0960-0760(00)00108-4","article-title":"Estrogen receptor pathways to AP-1","volume":"74","author":"Kushner","year":"2000","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib70","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/pros.2990160408","article-title":"Histological localization of estrogen receptors in normal and diseased human prostates by immunocytochemistry","volume":"16","author":"Schulze","year":"1990","journal-title":"Prostate"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib71","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1210\/endo-121-5-1773","article-title":"Immunocytochemical localization of estrogen receptors in the normal male and female canine urinary tract and prostate","volume":"121","author":"Schulze","year":"1987","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib72","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1095\/biolreprod42.1.11","article-title":"Estrogen and progestin receptors in the reproductive tract of male and female primates","volume":"42","author":"Brenner","year":"1990","journal-title":"Biol Reprod"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib73","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1210\/en.138.5.1801","article-title":"Neonatal estrogen exposure up-regulates estrogen receptor expression in the developing and adult rat prostate lobes","volume":"138","author":"Prins","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib74","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1210\/jc.2002-021015","article-title":"Zone-dependent expression of estrogen receptors alpha and beta in human benign prostatic hyperplasia","volume":"88","author":"Tsurusaki","year":"2003","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.steroids.2007.10.013_bib75","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/pros.2990150213","article-title":"Effect of pubertal development on estrogen receptor levels and stromal morphology in the guinea pig prostate","volume":"15","author":"Tilley","year":"1989","journal-title":"Prostate"},{"issue":"1","key":"10.1016\/j.steroids.2007.10.013_bib76","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/pros.10103","article-title":"Expression of estrogen receptor beta in the fetal, neonatal, and prepubertal human prostate","volume":"52","author":"Adams","year":"2002","journal-title":"Prostate"},{"key":"10.1016\/j.steroids.2007.10.013_bib77","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/S0022-5347(01)65749-5","article-title":"Elevated estrogen receptor expression in human prostatic stromal cells by androgen ablation therapy","volume":"156","author":"Kruithof-Dekker","year":"1996","journal-title":"J Urol"},{"key":"10.1016\/j.steroids.2007.10.013_bib78","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1677\/joe.0.1120139","article-title":"Effects of ageing and hormonal manipulations on the level of oestrogen receptors in the guinea-pig prostate","volume":"112","author":"Tilley","year":"1987","journal-title":"J Endocr"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib79","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1097\/01.ju.0000176472.90432.5b","article-title":"Immunolocalization of estrogen receptor alpha and beta in human fetal prostate","volume":"174","author":"Shapiro","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.steroids.2007.10.013_bib80","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/pros.2990030503","article-title":"Nuclei of stroma: site of highest estrogen concentration in human benign prostatic hyperplasia","volume":"3","author":"Kozak","year":"1982","journal-title":"Prostate"},{"key":"10.1016\/j.steroids.2007.10.013_bib81","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1006\/dbio.2000.9994","article-title":"Evidence that epithelial and mesenchymal estrogen receptor-\u03b1 mediates effects of estrogen on prostatic epithelium","volume":"229","author":"Risbridger","year":"2001","journal-title":"Develop Biol"},{"key":"10.1016\/j.steroids.2007.10.013_bib82","first-page":"6089","article-title":"Estrogen imprinting of the developing prostate gland in mediated through stromal estrogen receptor \u03b1: studies with \u03b1ERKO and \u03b2ERKO mice","volume":"61","author":"Prins","year":"2001","journal-title":"Cancer Res"},{"issue":"11","key":"10.1016\/j.steroids.2007.10.013_bib83","doi-asserted-by":"crossref","first-page":"4796","DOI":"10.1210\/en.137.11.4796","article-title":"Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility","volume":"137","author":"Eddy","year":"1996","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib84","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/j.1939-4640.1996.tb01756.x","article-title":"Morphometric study of the gubernaculum in male estrogen receptor mutant mice","volume":"17","author":"Donaldson","year":"1996","journal-title":"J Androl"},{"key":"10.1016\/j.steroids.2007.10.013_bib85","first-page":"702","article-title":"Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression","volume":"60","author":"Li","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib86","first-page":"3175","article-title":"Expression of estrogen receptor (ER)-\u03b1 and ER-\u03b2 in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation","volume":"60","author":"Lau","year":"2000","journal-title":"Cancer Res"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib87","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0002-9440(10)65160-7","article-title":"Estrogen receptor in prostate cancer and premalignant lesions","volume":"155","author":"Bonkhoff","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.steroids.2007.10.013_bib88","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0002-9440(10)61676-8","article-title":"Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate gland, dysplasia, and in primary and metastatic carcinoma","volume":"1","author":"Leav","year":"2001","journal-title":"Am J Pathol"},{"key":"10.1016\/j.steroids.2007.10.013_bib89","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0022-5347(05)00240-5","article-title":"Association between estrogen receptor alpha gene polymorphism and risk of prostate cancer in black men","volume":"175","author":"Hernandez","year":"2006","journal-title":"J Urol"},{"key":"10.1016\/j.steroids.2007.10.013_bib90","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/mc.10138","article-title":"Polymorphisms of estrogen receptor alpha in prostate cancer","volume":"37","author":"Tanaka","year":"2003","journal-title":"Mol Carcinogen"},{"issue":"12","key":"10.1016\/j.steroids.2007.10.013_bib91","first-page":"42584265","article-title":"Human estrogen receptor \u03b2\u2014gene structure, chromosomal localization, and expression pattern","volume":"82","author":"Enmark","year":"1997","journal-title":"JCEM"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib92","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1210\/en.139.3.874","article-title":"Estrogen receptor-\u03b2 messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats","volume":"139","author":"Prins","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib93","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0303-7207(00)00233-1","article-title":"Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract","volume":"164","author":"Makela","year":"2000","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.steroids.2007.10.013_bib94","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/(SICI)1097-0045(19990701)40:2<115::AID-PROS7>3.0.CO;2-3","article-title":"Estrogen receptor-\u03b2: implications for the prostate gland","volume":"40","author":"Chang","year":"1999","journal-title":"Prostate"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib95","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1507\/endocrj.50.281","article-title":"Regulation of estrogen receptor alpha and beta expression by testosterone in the rat prostate gland","volume":"50","author":"Asano","year":"2003","journal-title":"Endocr J"},{"key":"10.1016\/j.steroids.2007.10.013_bib96","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/pros.10171","article-title":"Differential expression of estrogen receptor beta in human prostate tissue, premalignant changes and in primary, metastatic and recurrent prostatic adenocarcinoma","volume":"54","author":"Fixemer","year":"2003","journal-title":"Prostate"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib97","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1006\/bbrc.2001.6038","article-title":"Differential expression of estrogen receptor beta (ERbeta) and its C-terminal truncated splice variant ERbetacx as prognostic predictors in human prostatic cancer","volume":"289","author":"Fujimura","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.steroids.2007.10.013_bib98","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1210\/me.13.1.129","article-title":"Functional analysis of a novel estrogen receptor beta isoform","volume":"13","author":"Hanstein","year":"1999","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.steroids.2007.10.013_bib99","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1006\/bbrc.1998.8590","article-title":"A novel isoform of rat estrogen receptor beta with 18 amino acid insertion in the ligand binding domain as a putative dominant negative regular of estrogen action","volume":"246","author":"Maruyama","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.steroids.2007.10.013_bib100","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1210\/en.139.3.1082","article-title":"Identification of estrogen receptor beta 2: a functional variant of estrogen receptor beta expressed in normal rat tissues","volume":"139","author":"Petersen","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib101","doi-asserted-by":"crossref","first-page":"9375","DOI":"10.1073\/pnas.0403041101","article-title":"Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate","volume":"101","author":"Imamov","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"issue":"11","key":"10.1016\/j.steroids.2007.10.013_bib102","doi-asserted-by":"crossref","first-page":"6330","DOI":"10.1073\/pnas.111150898","article-title":"A role for estrogen receptor beta in the regulation of growth of the ventral prostate","volume":"98","author":"Weihua","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.steroids.2007.10.013_bib103","first-page":"1","article-title":"Estrogen receptor beta in the prostate","volume":"193","author":"Weihua","year":"2002","journal-title":"Mol Cell Biol"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib104","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0960-0760(00)00105-9","article-title":"Receptor null mice reveal contrasting roles for estrogen receptor alpha and beta in reproductive tissues","volume":"74","author":"Couse","year":"2000","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"19","key":"10.1016\/j.steroids.2007.10.013_bib105","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1242\/dev.127.19.4277","article-title":"Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes","volume":"127","author":"Dupont","year":"2000","journal-title":"Development"},{"issue":"2","key":"10.1016\/j.steroids.2007.10.013_bib106","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1210\/en.2006-0906","article-title":"Essential role for estrogen receptor beta in stromal-epithelial regulation of prostatic hyperplasia","volume":"148","author":"McPherson","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2007.10.013_bib107","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S1567-5769(01)00045-5","article-title":"Estrogen, prolactin, and autoimmunity: actions and interactions","volume":"1","author":"McMurray","year":"2001","journal-title":"Int Immunopharm"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib108","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1385\/ENDO:12:3:207","article-title":"Normal development of thymus in male and female mice requires estrogen\/estrogen receptor-alpha signaling pathway","volume":"12","author":"Yellayi","year":"2000","journal-title":"Endocrine"},{"issue":"10","key":"10.1016\/j.steroids.2007.10.013_bib109","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1210\/en.2003-0550","article-title":"Evaluation of an estrogen receptor-beta agonist in animal models of human disease","volume":"144","author":"Harris","year":"2003","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.steroids.2007.10.013_bib110","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1016\/S0002-9440(10)65517-4","article-title":"Proliferative inflammatory atrophy of the prostate implications for prostatic carcinogenesis","volume":"155","author":"DeMarzo","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.steroids.2007.10.013_bib111","first-page":"25443","article-title":"Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-\u03b1 and estrogen receptor-\u03b2","volume":"273","author":"Montano","year":"1998","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.steroids.2007.10.013_bib112","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1023\/A:1020110718701","article-title":"The diet, prostate inflammation, and the development of prostate cancer","volume":"21","author":"Nelson","year":"2002","journal-title":"Cancer Metast Rev"},{"key":"10.1016\/j.steroids.2007.10.013_bib113","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1210\/jc.86.5.2051","article-title":"Loss of estrogen receptor beta expression in malignant human prostate cells in primary cultures and in prostate cancer tissues","volume":"86","author":"Pasquali","year":"2001","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.steroids.2007.10.013_bib114","first-page":"5331","article-title":"Frequent loss of estrogen receptor-beta expression in prostate cancer","volume":"61","author":"Horvath","year":"2001","journal-title":"Cancer Res"},{"issue":"6","key":"10.1016\/j.steroids.2007.10.013_bib115","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1016\/S0002-9440(10)63760-1","article-title":"Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis","volume":"164","author":"Zhu","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.steroids.2007.10.013_bib116","doi-asserted-by":"crossref","first-page":"7246","DOI":"10.1038\/sj.onc.1210537","article-title":"AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells","volume":"26","author":"Zhang","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.steroids.2007.10.013_bib117","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.febslet.2004.04.025","article-title":"Expression of estrogen receptor beta in prostate carcinoma cells inhibits invasion and proliferation and triggers apoptosis","volume":"566","author":"Cheng","year":"2004","journal-title":"FEBS Lett"},{"key":"10.1016\/j.steroids.2007.10.013_bib118","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.urology.2004.05.036","article-title":"Metastases of prostate cancer express estrogen receptor-beta","volume":"64","author":"Lai","year":"2004","journal-title":"Urology"},{"key":"10.1016\/j.steroids.2007.10.013_bib119","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/0002-9343(80)90267-3","article-title":"The pathogenesis of benign prostatic hyperplasia","volume":"68","author":"Wilson","year":"1980","journal-title":"Am J Med"},{"issue":"12","key":"10.1016\/j.steroids.2007.10.013_bib120","doi-asserted-by":"crossref","first-page":"5445","DOI":"10.1158\/0008-5472.CAN-04-1941","article-title":"The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype","volume":"65","author":"Guerini","year":"2005","journal-title":"Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib121","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1158\/1078-0432.CCR-05-2068","article-title":"2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6","volume":"12","author":"Garcia","year":"2006","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib122","first-page":"2867","article-title":"Evaluation of the cytotoxic activity of diethylstilbestrol and its mono- and diphosphate towards prostatic carcinoma cells","volume":"48","author":"Schulz","year":"1988","journal-title":"Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib123","first-page":"5365","article-title":"Raloxifene, a mixed estrogen agonist\/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines","volume":"62","author":"Kim","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib124","first-page":"6056","article-title":"The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model","volume":"63","author":"Neubauer","year":"2003","journal-title":"Cancer Res"},{"issue":"4","key":"10.1016\/j.steroids.2007.10.013_bib125","first-page":"1003","article-title":"Inhibition of androgen-independent growth of prostate cancer xenografts by 17beta-estradiol","volume":"8","author":"Corey","year":"2002","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.steroids.2007.10.013_bib126","first-page":"1370","article-title":"Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model","volume":"62","author":"Raghow","year":"2002","journal-title":"Cancer Res"},{"issue":"9","key":"10.1016\/j.steroids.2007.10.013_bib127","first-page":"2366","article-title":"A Phase II study of high-dose tamoxifen in patients with hormone-refractory prostate cancer","volume":"5","author":"Bergan","year":"1999","journal-title":"Clin Cancer Res"},{"issue":"3","key":"10.1016\/j.steroids.2007.10.013_bib128","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1097\/00000421-200106000-00015","article-title":"Phase II trial of toremifene in androgen-independent prostate cancer: a Penn cancer clinical trials group trial","volume":"24","author":"Stein","year":"2001","journal-title":"Am J Clin Oncol"},{"issue":"1","key":"10.1016\/j.steroids.2007.10.013_bib129","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3816\/CGC.2003.n.009","article-title":"Phase IIA clinical trials to test the efficacy and safety of Toremifene in men with high-grade prostatic intraepithelial neoplasia","volume":"2","author":"Steiner","year":"2003","journal-title":"Clin Prostate Cancer"},{"key":"10.1016\/j.steroids.2007.10.013_bib130","first-page":"1","article-title":"Aromatase and prostate cancer","volume":"31","author":"Ellem","year":"2006","journal-title":"Minerva Endocrinol"},{"issue":"6","key":"10.1016\/j.steroids.2007.10.013_bib131","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2174\/1568011043352669","article-title":"Aromatase inhibitors: a new paradigm in breast cancer treatment","volume":"4","author":"Narashimamurthy","year":"2004","journal-title":"Curr Med Chem Anticancer Agents"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib132","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1210\/jc.2003-030933","article-title":"Local aromatase expression in human prostate is altered in malignancy","volume":"89","author":"Ellem","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"10.1016\/j.steroids.2007.10.013_bib133","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1002\/cncr.10844","article-title":"Selective aromatase inhibition for patients with androgen-independent prostate carcinoma","volume":"95","author":"Smith","year":"2002","journal-title":"Cancer"},{"issue":"8","key":"10.1016\/j.steroids.2007.10.013_bib134","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1002\/1097-0142(20011015)92:8<2095::AID-CNCR1550>3.0.CO;2-Y","article-title":"Use of the aromatase inhibitor anastrozole in the treatment of patients with advanced prostate carcinoma","volume":"92","author":"Santen","year":"2001","journal-title":"Cancer"},{"issue":"11-18","key":"10.1016\/j.steroids.2007.10.013_bib135","article-title":"Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats","volume":"186","author":"Wang","year":"2002","journal-title":"Cancer Lett"},{"issue":"5","key":"10.1016\/j.steroids.2007.10.013_bib136","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1093\/jn\/135.5.989","article-title":"Dietary genistein improves survival and reduces expression of osteopontin in the prostate of transgenic mice with prostatic adenocarcinoma (TRAMP)","volume":"135","author":"Mentor-Marcel","year":"2005","journal-title":"J Nutr"},{"key":"10.1016\/j.steroids.2007.10.013_bib137","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1158\/1055-9965.EPI-04-0398","article-title":"Resveratrol-induced gene expression profiles in human prostate cancer cells","volume":"14","author":"Jones","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.steroids.2007.10.013_bib138","first-page":"665","article-title":"Soy and isoflavone consumption in relation to prostate cancer risk in China","volume":"12","author":"Lee","year":"2003","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"1","key":"10.1016\/j.steroids.2007.10.013_bib139","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1349-7006.2004.tb03172.x","article-title":"Serum phytoestrogens and prostate cancer risk in a nested case\u2013control study among Japanese men","volume":"95","author":"Ozasa","year":"2004","journal-title":"Cancer Sci"},{"key":"10.1016\/j.steroids.2007.10.013_bib140","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/3-540-26980-0_17","article-title":"Innovative agents in cancer prevention","volume":"166","author":"Manson","year":"2005","journal-title":"Rec Results Cancer Res"},{"issue":"11","key":"10.1016\/j.steroids.2007.10.013_bib141","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1593\/neo.06538","article-title":"Apigenin suppresses cancer cell growth through ERbeta","volume":"8","author":"Mak","year":"2006","journal-title":"Neoplasia"}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X07002103?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X07002103?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,18]],"date-time":"2024-02-18T19:05:59Z","timestamp":1708283159000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X07002103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":141,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0039128X07002103"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2007.10.013","relation":{},"ISSN":["0039-128X"],"issn-type":[{"value":"0039-128X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]}}}