{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T11:21:24Z","timestamp":1773832884832,"version":"3.50.1"},"reference-count":59,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.steroids.2010.10.005","type":"journal-article","created":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T08:35:24Z","timestamp":1288082124000},"page":"145-155","source":"Crossref","is-referenced-by-count":18,"title":["Novel components of the human metabolome: The identification, characterization and anti-inflammatory activity of two 5-androstene tetrols"],"prefix":"10.1016","volume":"76","author":[{"given":"Clarence N.","family":"Ahlem","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore M.","family":"Page","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominick L.","family":"Auci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia","family":"Mangano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"Nicoletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven K.","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Villegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Conrad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Reading","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M.","family":"Frincke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.steroids.2010.10.005_bib0005","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1210\/endo-103-6-2112","article-title":"Adrenarche: a survey of rodents, domestic animals, and primates","volume":"103","author":"Cutler","year":"1978","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2010.10.005_bib0010","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1055\/s-2007-1001696","article-title":"Sex differences in dehydroepiandrosterone metabolism in the rat: different plasma levels following ingestion of DHEA-supplemented diet and different metabolite patterns in plasma, bile and urine","volume":"26","author":"Hobe","year":"1994","journal-title":"Horm Metab Res"},{"key":"10.1016\/j.steroids.2010.10.005_bib0015","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1055\/s-0029-1210342","article-title":"Serum levels of testosterone precursors, testosterone and estradiol in 10 animal species","volume":"83","author":"Wichmann","year":"1984","journal-title":"Exp Clin Endocrinol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0020","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0022-4731(89)90514-1","article-title":"Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: unique importance of extratesticular androgens in men","volume":"32","author":"Belanger","year":"1989","journal-title":"J Steroid Biochem"},{"key":"10.1016\/j.steroids.2010.10.005_bib0025","doi-asserted-by":"crossref","first-page":"377","DOI":"10.2174\/1568010054022079","article-title":"Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders","volume":"4","author":"Dillon","year":"2005","journal-title":"Curr Drug Targets Inflamm Allergy"},{"key":"10.1016\/j.steroids.2010.10.005_bib0030","doi-asserted-by":"crossref","first-page":"174","DOI":"10.3181\/00379727-218-44285","article-title":"The actions of exogenous dehydroepiandrosterone in experimental animals and humans","volume":"218","author":"Svec","year":"1998","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.steroids.2010.10.005_bib0035","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1093\/rheumatology\/37.6.705","article-title":"Effects of dehydroepiandrosterone administration on disease activity in patients with rheumatoid arthritis [letter]","volume":"37","author":"Giltay","year":"1998","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0040","first-page":"1723","article-title":"DHEA: panacea or snake oil?","volume":"45","author":"Sirrs","year":"1999","journal-title":"Can Fam Physician"},{"key":"10.1016\/j.steroids.2010.10.005_bib0045","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1258\/175404507780796370","article-title":"Dehydroepiandrosterone (DHEA) and the menopause: an update","volume":"13","author":"Raven","year":"2007","journal-title":"Menopause Int"},{"key":"10.1016\/j.steroids.2010.10.005_bib0050","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S0002-9378(11)90602-4","article-title":"Postmenopausal steroid replacement with micronized dehydroepiandrosterone: preliminary oral bioavailability and dose proportionality studies","volume":"166","author":"Buster","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0055","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1006\/abbi.2001.2341","article-title":"Metabolism of DHEA by cytochromes P450 in rat and human liver microsomal fractions","volume":"389","author":"Fitzpatrick","year":"2001","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.steroids.2010.10.005_bib0060","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1210\/jc.2003-022012","article-title":"Bioavailability and pharmacokinetics of dehydroepiandrosterone in the cynomolgus monkey","volume":"88","author":"Leblanc","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2010.10.005_bib0065","series-title":"Dehydroepiandrosterone (DHEA): Biochemical, Physiological and Clinical Aspects","first-page":"65","article-title":"Restoration of immunocompetence in aging and other inflammatory disease states by dehydroepiandrosterone-3\u03b2-sulfate, an activator of the peroxisome proliferator-activated receptor alpha (PPAR\u03b1)","author":"Poynter","year":"1999"},{"key":"10.1016\/j.steroids.2010.10.005_bib0070","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1073\/pnas.0307325101","article-title":"Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex","volume":"101","author":"Suzuki","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.steroids.2010.10.005_bib0075","first-page":"128","article-title":"Differential effects of dehydroepiandrosterone (DHEA) on murine lymphopoiesis and myelopoiesis","volume":"19","author":"Risdon","year":"1991","journal-title":"Exp Hematol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0080","doi-asserted-by":"crossref","first-page":"E1465","DOI":"10.1152\/ajpendo.00516.2007","article-title":"Adrenocortical dysregulation as a major player in insulin resistance and onset of obesity","volume":"293","author":"Roberge","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.steroids.2010.10.005_bib0085","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1210\/jc.82.8.2403","article-title":"Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology","volume":"82","author":"Labrie","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2010.10.005_bib0090","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1677\/joe.1.06264","article-title":"Is dehydroepiandrosterone a hormone?","volume":"187","author":"Labrie","year":"2005","journal-title":"J Endocrinol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0095","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S1570-0232(01)00570-0","article-title":"Metabolism of dehydroepiandrosterone by rat liver in vitro: a liquid chromatographic-mass spectrometric study","volume":"767","author":"Marwah","year":"2002","journal-title":"J Chromatogr B Biomed Sci Appl"},{"key":"10.1016\/j.steroids.2010.10.005_bib0100","first-page":"64","article-title":"The immunobiology and therapeutic potential of androstene hormones and their synthetic derivatives: novel anti-inflammatory and immune regulating steroid hormones","volume":"3","author":"Auci","year":"2003","journal-title":"Mod Asp Immunobiol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0105","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1196\/annals.1423.066","article-title":"A new orally bioavailable synthetic androstene inhibits collagen-induced arthritis in the mouse","volume":"1110","author":"Auci","year":"2007","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.steroids.2010.10.005_bib0110","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1196\/annals.1361.117","article-title":"Anti-inflammatory and immune regulatory properties of 5-androsten-3{beta}, 17{beta}-diol (HE2100), and synthetic analogue HE3204: implications for treatment of autoimmune diseases","volume":"1051","author":"Auci","year":"2005","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.steroids.2010.10.005_bib0115","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1124\/jpet.108.145086","article-title":"An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis","volume":"329","author":"Offner","year":"2009","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.steroids.2010.10.005_bib0120","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0165-5728(02)00214-X","article-title":"A synthetic androstene derivative and a natural androstene metabolite inhibit relapsing-remitting EAE","volume":"130","author":"Offner","year":"2002","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0125","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jsbmb.2007.12.014","article-title":"Anti-inflammatory effects and changes in prostaglandin patterns induced by 7beta-hydroxy-epiandrosterone in rats with colitis","volume":"110","author":"Hennebert","year":"2008","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0130","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.steroids.2008.05.001","article-title":"7beta-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes","volume":"73","author":"Le Mee","year":"2008","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2010.10.005_bib0135","first-page":"505","article-title":"Control of the immune response by DHEA and its metabolites","volume":"46","author":"Loria","year":"1998","journal-title":"Rinsho Byori"},{"key":"10.1016\/j.steroids.2010.10.005_bib0140","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0165-5728(97)00244-0","article-title":"Endocrine regulation of murine macrophage function: effects of dehydroepiandrosterone, androstenediol, and androstenetriol","volume":"84","author":"Padgett","year":"1998","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0145","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.autrev.2008.11.011","article-title":"7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases","volume":"8","author":"Auci","year":"2009","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.steroids.2010.10.005_bib0150","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.resuscitation.2006.03.020","article-title":"Androstenetriol improves survival in a rodent model of traumatic shock","volume":"71","author":"Marcu","year":"2006","journal-title":"Resuscitation"},{"key":"10.1016\/j.steroids.2010.10.005_bib0155","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1038\/sj.bjc.6604987","article-title":"Inhibition of androstenediol-dependent LNCaP tumour growth by 17alpha-ethynyl-5alpha-androstane-3alpha, 17beta-diol (HE3235)","volume":"100","author":"Trauger","year":"2009","journal-title":"Br J Cancer"},{"key":"10.1016\/j.steroids.2010.10.005_bib0160","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1124\/jpet.109.161182","article-title":"Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways","volume":"333","author":"Wang","year":"2010","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.steroids.2010.10.005_bib0165","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.3109\/00498259009046838","article-title":"Design of toxicokinetic studies","volume":"20","author":"Smith","year":"1990","journal-title":"Xenobiotica"},{"key":"10.1016\/j.steroids.2010.10.005_bib0170","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1517\/17425255.1.2.175","article-title":"Caco-2 cell permeability assays to measure drug absorption","volume":"1","author":"van Breemen","year":"2005","journal-title":"Expert Opin Drug Metab Toxicol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0175","first-page":"625","article-title":"Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis","author":"Auci","year":"2010","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.steroids.2010.10.005_bib0180","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/j.1749-6632.2009.04798.x","article-title":"HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease","volume":"1173","author":"Ahlem","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.steroids.2010.10.005_bib0185","doi-asserted-by":"crossref","first-page":"8504","DOI":"10.4049\/jimmunol.177.12.8504","article-title":"Treatment of experimental autoimmune prostatitis in nonobese diabetic mice by the vitamin D receptor agonist elocalcitol","volume":"177","author":"Penna","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0190","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/0016-5085(84)90202-6","article-title":"Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models","volume":"87","author":"Krawisz","year":"1984","journal-title":"Gastroenterology"},{"key":"10.1016\/j.steroids.2010.10.005_bib0195","doi-asserted-by":"crossref","first-page":"G1328","DOI":"10.1152\/ajpgi.00467.2004","article-title":"Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL\/6 but not in BALB\/c mice: correlation between symptoms and inflammation","volume":"288","author":"Melgar","year":"2005","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0200","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1006\/jaut.1998.0248","article-title":"Non-obese diabetic (NOD) mice are genetically susceptible to experimental autoimmune prostatitis (EAP)","volume":"11","author":"Rivero","year":"1998","journal-title":"J Autoimmun"},{"key":"10.1016\/j.steroids.2010.10.005_bib0205","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2165\/00151829-200403030-00003","article-title":"Role of neutrophils in mucus hypersecretion in COPD and implications for therapy","volume":"3","author":"Kim","year":"2004","journal-title":"Treat Respir Med"},{"key":"10.1016\/j.steroids.2010.10.005_bib0210","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1006\/pupt.2000.0231","article-title":"Lipopolysaccharide-induced lung injury in mice. I. Concomitant evaluation of inflammatory cells and haemorrhagic lung damage","volume":"13","author":"Asti","year":"2000","journal-title":"Pulm Pharmacol Ther"},{"key":"10.1016\/j.steroids.2010.10.005_bib0215","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.3748\/wjg.14.1972","article-title":"Current view of the immunopathogenesis in inflammatory bowel disease and its implications for therapy","volume":"14","author":"Torres","year":"2008","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0220","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jsbmb.2005.12.001","article-title":"Inter-conversion of 7alpha- and 7beta-hydroxy-dehydroepiandrosterone by the human 11beta-hydroxysteroid dehydrogenase type 1","volume":"99","author":"Muller","year":"2006","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0225","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.steroids.2007.07.011","article-title":"5Alpha-androstane-3beta,7alpha,17beta-triol and 5alpha-androstane-3beta,7beta,17beta-triol as substrates for the human 11beta-hydroxysteroid dehydrogenase type 1","volume":"72","author":"Hennebert","year":"2007","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2010.10.005_bib0295","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1016\/j.intimp.2006.07.005","article-title":"5-Androstenediol stimulates multilineage hematopoiesis in rhesus monkeys with radiation-induced myelosuppression","volume":"6","author":"Stickney","year":"2006","journal-title":"Int Immunopharmacol."},{"key":"10.1016\/j.steroids.2010.10.005_bib0230","doi-asserted-by":"crossref","first-page":"E1036","DOI":"10.1152\/ajpendo.00668.2009","article-title":"A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats","volume":"298","author":"Lu","year":"2010","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.steroids.2010.10.005_bib0235","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0039-128X(76)90055-6","article-title":"Water-soluble metabolites of the estrogens. Quantitation of C-18 tetrols in rat feces","volume":"27","author":"Elce","year":"1976","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2010.10.005_bib0240","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jsbmb.2005.04.034","article-title":"Estrogen A-ring structure and antioxidative effect on lipoproteins","volume":"96","author":"Badeau","year":"2005","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0245","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0039-128X(87)90024-9","article-title":"Concerning the pathway from 19-oxoandrost-4-ene-3,17-dione to estrone","volume":"50","author":"Caspi","year":"1987","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2010.10.005_bib0250","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/0022-4731(82)90565-9","article-title":"Assay of estrogens in human feces","volume":"17","author":"Adlercreutz","year":"1982","journal-title":"J Steroid Biochem"},{"key":"10.1016\/j.steroids.2010.10.005_bib0255","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0960-0760(94)90013-2","article-title":"Urinary steroids from a newborn human infant. Identification of 2 alpha-hydroxy-4-pregnene-3,20-dione, 3 beta,15 beta-dihydroxy-5-pregnen-20-one and 3 beta,15 alpha-dihydroxy-5-pregnen-20-one","volume":"49","author":"Gachancard-Bouya","year":"1994","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0260","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0022-4731(83)90398-9","article-title":"Characterization of the major steroids present in amniotic fluid obtained between the 15th and 17th weeks of gestation","volume":"19","author":"Homoki","year":"1983","journal-title":"J Steroid Biochem"},{"key":"10.1016\/j.steroids.2010.10.005_bib0265","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0039-128X(87)90002-X","article-title":"Synthesis of 16 alpha,19-dihydroxy-4-androstene-3,17-dione and 3 beta,16 alpha,19-trihydroxy-5-androsten-17-one and their 17 beta-hydroxy-16-keto isomers","volume":"49","author":"Numazawa","year":"1987","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2010.10.005_bib0270","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s11745-002-1019-7","article-title":"Transformations of DHEA and its metabolites by rat liver","volume":"37","author":"Lardy","year":"2002","journal-title":"Lipids"},{"key":"10.1016\/j.steroids.2010.10.005_bib0275","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1365-2249.2008.03696.x","article-title":"Dehydroepiandrosterone and metformin regulate proliferation of murine T lymphocytes","volume":"153","author":"Solano","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0280","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0026-895X(25)09162-X","article-title":"Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate","volume":"50","author":"Peters","year":"1996","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0285","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.mce.2010.02.017","article-title":"Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue","volume":"320","author":"Rice","year":"2010","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.steroids.2010.10.005_bib0290","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1210\/en.2007-1125","article-title":"Dehydroepiandrosterone stimulates endothelial proliferation and angiogenesis through extracellular signal-regulated kinase 1\/2-mediated mechanisms","volume":"149","author":"Liu","year":"2008","journal-title":"Endocrinology"}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X10002576?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X10002576?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T07:09:08Z","timestamp":1740640148000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X10002576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":59,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S0039128X10002576"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2010.10.005","relation":{},"ISSN":["0039-128X"],"issn-type":[{"value":"0039-128X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}