{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:35:16Z","timestamp":1791318916045,"version":"4.3.1"},"reference-count":89,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.steroids.2013.05.004","type":"journal-article","created":{"date-parts":[[2013,5,20]],"date-time":"2013-05-20T22:36:41Z","timestamp":1369089401000},"page":"734-740","source":"Crossref","is-referenced-by-count":116,"title":["Animal models of the polycystic ovary syndrome phenotype"],"prefix":"10.1016","volume":"78","author":[{"given":"Vasantha","family":"Padmanabhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almudena","family":"Veiga-Lopez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.steroids.2013.05.004_b0005","series-title":"Polycystic ovary syndrome","first-page":"377","article-title":"Diagnostic criteria for polycystic ovary syndrome: towards a rational approach","author":"Zawadki","year":"1992"},{"key":"10.1016\/j.steroids.2013.05.004_b0010","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/humrep\/deh098","article-title":"Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)","volume":"19","author":"The Rotterdam ESHRE\/ASRM-Sponsored PCOS consensus workshop group","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0015","doi-asserted-by":"crossref","first-page":"4237","DOI":"10.1210\/jc.2006-0178","article-title":"Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an androgen excess society guideline","volume":"91","author":"Azziz","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0020","unstructured":"Evidence-based methodology workshop on polycystic ovary syndrome. Final report, National Institutes of Health. December 3\u20135, 2012. <http:\/\/prevention.nih.gov\/workshops\/2012\/pcos\/>."},{"key":"10.1016\/j.steroids.2013.05.004_b0025","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0950-351X(96)80127-3","article-title":"Polycystic ovary syndrome: induction of ovulation","volume":"10","author":"Homburg","year":"1996","journal-title":"Baillieres Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0030","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1093\/humrep\/dei128","article-title":"Ovulation induction: a mini review","volume":"20","author":"Messinis","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0035","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0950-3552(05)80313-X","article-title":"Common problems in induction of ovulation","volume":"4","author":"Hamilton-Fairley","year":"1990","journal-title":"Baillieres Clin Obstet Gynaecol"},{"key":"10.1016\/j.steroids.2013.05.004_b0040","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1055\/s-2007-992927","article-title":"Pregnancy complications in women with polycystic ovary syndrome","volume":"26","author":"Boomsma","year":"2008","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.steroids.2013.05.004_b0045","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1097\/01.ogx.0000243772.33357.84","article-title":"Polycystic ovary syndrome and mental health: a review","volume":"61","author":"Himelein","year":"2006","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.steroids.2013.05.004_b0050","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1055\/s-2007-992924","article-title":"Mood and sexual function in polycystic ovary syndrome","volume":"26","author":"Janssen","year":"2008","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.steroids.2013.05.004_b0055","first-page":"CD003053","article-title":"Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome","volume":"3","author":"Lord","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.steroids.2013.05.004_b0060","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1007\/BF03345554","article-title":"The metabolic syndrome in polycystic ovary syndrome","volume":"29","author":"Essah","year":"2006","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.steroids.2013.05.004_b0065","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1365-2265.2006.02587.x","article-title":"Obesity and polycystic ovary syndrome","volume":"65","author":"Barber","year":"2006","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.steroids.2013.05.004_b0070","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1210\/er.18.6.774","article-title":"Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis","volume":"18","author":"Dunaif","year":"1997","journal-title":"Endocr Rev"},{"key":"10.1016\/j.steroids.2013.05.004_b0075","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/ncpendmet0755","article-title":"Cardiometabolic features of polycystic ovary syndrome","volume":"4","author":"Hoffman","year":"2008","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0080","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1055\/s-2007-992926","article-title":"Polycystic ovary syndrome and endometrial cancer","volume":"26","author":"Navaratnarajah","year":"2008","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.steroids.2013.05.004_b0085","series-title":"Mothers, babies, and disease in later life and disease in later life","first-page":"14","author":"Barker","year":"1994"},{"key":"10.1016\/j.steroids.2013.05.004_b0090","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11154-007-9046-0","article-title":"Polycystic ovary syndrome and its developmental origins","volume":"8","author":"Dumesic","year":"2007","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.steroids.2013.05.004_b0095","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S1043-2760(02)00691-4","article-title":"Programming and reproductive functioning","volume":"13","author":"Davies","year":"2002","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0100","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1210\/jc.79.5.1328","article-title":"Ovarian hyperandrogenism as a result of congenital adrenal virilizing disorders: evidence for prenatal masculanization of neuroendocrine function in women","volume":"79","author":"Barnes","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0105","series-title":"Contemporary endocrinology: androgen excess disorders in women: polycystic ovary syndrome and other disorders","first-page":"259","article-title":"Animal models and fetal programming of PCOS","author":"Abbott","year":"2006"},{"key":"10.1016\/j.steroids.2013.05.004_b0110","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1055\/s-0031-1275519","article-title":"Developmental origin of reproductive and metabolic dysfunctions: androgenic versus estrogenic reprogramming","volume":"29","author":"Padmanabhan","year":"2011","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.steroids.2013.05.004_b0115","article-title":"Sheep models of polycystic ovary syndrome phenotype","author":"Padmanabhan","year":"2012","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.steroids.2013.05.004_b0120","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1095\/biolreprod17.4.584","article-title":"Luteinizing hormone and progesterone secretion during sexual maturation of rhesus monkey -short luteal phases during initial menstrual cycles","volume":"17","author":"Foster","year":"1977","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0125","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1530\/jrf.0.0850583","article-title":"Season determines timing of first ovulation in rhesus monkeys (Macaca mulatta) housed outdoors","volume":"85","author":"Wilson","year":"1989","journal-title":"J Reprod Fertil"},{"key":"10.1016\/j.steroids.2013.05.004_b0130","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.yhbeh.2007.09.012","article-title":"An alternate pathway for androgen regulation of brain function: activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5alpha-androstane-3beta,17beta-diol","volume":"53","author":"Handa","year":"2008","journal-title":"Horm Behav"},{"key":"10.1016\/j.steroids.2013.05.004_b0135","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0950-3552(97)80039-9","article-title":"Current concepts of polycystic ovary syndrome","volume":"11","author":"Rosenfield","year":"1997","journal-title":"Baillieres Clin Obstet Gynaecol"},{"key":"10.1016\/j.steroids.2013.05.004_b0140","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/humupd\/dmi013","article-title":"Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?","volume":"11","author":"Abbott","year":"2005","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.steroids.2013.05.004_b0145","doi-asserted-by":"crossref","first-page":"7129","DOI":"10.1073\/pnas.0308058101","article-title":"Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder","volume":"101","author":"Sullivan","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.steroids.2013.05.004_b0150","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.1210\/en.2007-0168","article-title":"A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome","volume":"148","author":"Manneras","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0155","doi-asserted-by":"crossref","first-page":"3532","DOI":"10.1210\/en.2007-0339","article-title":"Developmental programming: follicular persistence in prenatal testosterone-treated sheep is not programmed by androgenic actions of testosterone","volume":"148","author":"Steckler","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0160","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1677\/JOE-10-0217","article-title":"Prenatal androgen exposure programs metabolic dysfunction in female mice","volume":"207","author":"Roland","year":"2010","journal-title":"J Endocrinol"},{"key":"10.1016\/j.steroids.2013.05.004_b0165","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1507\/endocrj.K09E-205","article-title":"Endocrine traits of polycystic ovary syndrome in prenatally androgenized female sprague-dawley rats","volume":"57","author":"Wu","year":"2010","journal-title":"Endocr J"},{"issue":"14","key":"10.1016\/j.steroids.2013.05.004_b0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/humupd\/dmm034","article-title":"Annual reproduction workshop group 2007. Predictors of ovarian response: progress towards individualized treatment in ovulation induction and ovarian stimulation","volume":"2008","author":"Fauser","year":"2007","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.steroids.2013.05.004_b0175","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1210\/jc.87.3.1111","article-title":"Impaired developmental competence of oocytes in adult prenatally androgenized female rhesus monkeys undergoing gonadotropin stimulation for in vitro fertilization","volume":"87","author":"Dumesic","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0180","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.theriogenology.2006.08.010","article-title":"Developmental programming in sheep: Administration of testosterone during 60 to 90 days of pregnancy reduces breeding success and pregnancy outcome","volume":"67","author":"Steckler","year":"2007","journal-title":"Theriogenology"},{"key":"10.1016\/j.steroids.2013.05.004_b0185","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0015-0282(97)81873-0","article-title":"Prenatal exposure of female rhesus monkeys to testosterone propionate increases serum luteinizing hormone levels in adulthood","volume":"67","author":"Dumesic","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.steroids.2013.05.004_b0190","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1095\/biolreprod66.4.924","article-title":"Fetal programming: prenatal androgen disrupts positive feedback actions of estradiol but does not affect timing of puberty in female sheep","volume":"66","author":"Sharma","year":"2002","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0195","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1210\/en.2005-0322","article-title":"Fetal programming: excess prenatal testosterone reduces postnatal LH, but not FSH responsiveness to estradiol negative feedback in the female","volume":"146","author":"Sarma","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0200","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1095\/biolreprod.107.063347","article-title":"Developmental programming: impact of prenatal testosterone excess on pre- and postnatal gonadotropin regulation in sheep","volume":"78","author":"Manikkam","year":"2008","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0205","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1095\/biolreprod.105.039800","article-title":"Neuroendocrine consequences of prenatal androgen exposure in the female rat: absence of luteinizing hormone surges, suppression of progesterone receptor gene expression, and acceleration of the gonadotropin-releasing hormone pulse generator","volume":"72","author":"Foecking","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0210","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1210\/jc.83.2.582","article-title":"Polycystic ovary syndrome: evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone","volume":"83","author":"Pastor","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0215","unstructured":"Levine J.E., Terasawa E., Hoffman S.M., Dobbert M.J.W., Foecking E.M., Abbott D.H. Luteinizing hormone (LH) hypersecretion and diminished LH responses to RU486 in a non-human primate model for polycystic ovary syndrome (PCOS). Paper presented at: Annual Meeting of the Endocrine Society; June 4, 2005; San Diego, CA."},{"key":"10.1016\/j.steroids.2013.05.004_b0220","doi-asserted-by":"crossref","first-page":"5797","DOI":"10.1210\/en.140.12.5797","article-title":"In utero exposure of female lambs to testosterone reduces the sensitivity of the gonadotropin-releasing hormone neuronal network to inhibition by progesterone","volume":"140","author":"Robinson","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0225","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1095\/biolreprod.107.065904","article-title":"Developmental programming: deficits in reproductive hormone dynamics and ovulatory outcomes in prenatal, testosterone-treated sheep","volume":"78","author":"Veiga-Lopez","year":"2008","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0230","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1095\/biolreprod.104.035691","article-title":"Prenatal programming of reproductive neuroendocrine function: the effect of prenatal androgens on the development of estrogen positive feedback and ovarian cycles in the ewe","volume":"72","author":"Unsworth","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0235","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1095\/biolreprod15.2.206","article-title":"Sexual differentiation and feedback control of luteinizing hormone secretion in the rhesus monkey","volume":"15","author":"Steiner","year":"1976","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0240","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1095\/biolreprod.108.074781","article-title":"Developmental programming: contribution of prenatal androgen and estrogen to estradiol feedback systems and periovulatory hormonal dynamics in sheep","volume":"80","author":"Veiga-Lopez","year":"2009","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0245","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.arcmed.2003.10.005","article-title":"Letrozole-induced polycystic ovaries in the rat: a new model for cystic ovarian disease","volume":"35","author":"Kafali","year":"2004","journal-title":"Arch Med Res"},{"key":"10.1016\/j.steroids.2013.05.004_b0250","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.arcmed.2006.04.006","article-title":"Microscopic characterization of follicular structures in letrozole-induced polycystic ovarian syndrome in the rat","volume":"37","author":"Baravalle","year":"2006","journal-title":"Arch Med Res"},{"key":"10.1016\/j.steroids.2013.05.004_b0255","doi-asserted-by":"crossref","first-page":"4289","DOI":"10.1210\/en.2003-0146","article-title":"Prepubertal administration of estradiol valerate disrupts cyclicity and leads to cystic ovarian morphology during adult life in the rat: role of sympathetic innervation","volume":"144","author":"Rosa-E-Silva","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0260","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1472-6483(10)61708-7","article-title":"Gonadotrophin regimens and oocyte quality in women with polycystic ovaries","volume":"6","author":"Franks","year":"2003","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.steroids.2013.05.004_b0265","series-title":"Polycystic ovary syndrome","first-page":"119","article-title":"Prenatal androgen excess programs for PCOS in female rhesus monkeys","author":"Abbott","year":"2002"},{"key":"10.1016\/j.steroids.2013.05.004_b0270","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0303-7207(01)00632-3","article-title":"Intra follicular activin availability is altered in prenatally-androgenized lambs","volume":"185","author":"West","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.steroids.2013.05.004_b0275","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1095\/biolreprod.108.072801","article-title":"Developmental programming: differential effects of prenatal testosterone and dihydrotestosterone on follicular recruitment, depletion of follicular reserve, and ovarian morphology in sheep","volume":"80","author":"Smith","year":"2009","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0280","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1210\/en.2005-1338","article-title":"Fetal programming: prenatal testosterone treatment leads to follicular persistence\/luteal defects; partial restoration of ovarian function by cyclic progesterone treatment","volume":"147","author":"Manikkam","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0285","doi-asserted-by":"crossref","first-page":"5582","DOI":"10.1210\/jc.2005-0695","article-title":"Follicular arrest in polycystic ovary syndrome is associated with deficient inhibin A and B biosynthesis","volume":"90","author":"Welt","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0290","doi-asserted-by":"crossref","first-page":"4206","DOI":"10.1210\/jc.86.9.4206","article-title":"Dynamics of inhibin subunit and follistatin mRNA during development of normal and polycystic ovary syndrome follicles","volume":"86","author":"Fujiwara","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0295","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1530\/REP-08-0491","article-title":"Developmental programming: prenatal androgen excess disrupts ovarian steroid receptor balance","volume":"137","author":"Ortega","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.steroids.2013.05.004_b0300","doi-asserted-by":"crossref","first-page":"5178","DOI":"10.1210\/en.2006-0679","article-title":"Adiponectin induces periovulatory changes in ovarian follicular cells","volume":"147","author":"Ledoux","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0305","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.112.100024","article-title":"Developmental programming: impact of prenatal testosterone excess on ovarian cell proliferation and apoptotic factors in sheep","volume":"87","author":"Salvetti","year":"2012","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0310","doi-asserted-by":"crossref","unstructured":"Diamanti-Kandarakis E. Role of obesity and adiposity in polycystic ovary syndrome. Int J Obes (Lond) 2007;31Suppl.2:S8\u201313; discussion S31\u20132.","DOI":"10.1038\/sj.ijo.0803730"},{"key":"10.1016\/j.steroids.2013.05.004_b0315","series-title":"Androgen excess disorders in women","first-page":"283","article-title":"The endocrine impact of obesity and body habitus in the polycystic syndrome","author":"Pasquali","year":"2007"},{"key":"10.1016\/j.steroids.2013.05.004_b0320","series-title":"Androgen excess disorders in women","first-page":"319","article-title":"\u03b2-cell dysfunction, glucose intolerance, and diabetes in the polycystic syndrome","author":"Ehrmann","year":"2007"},{"key":"10.1016\/j.steroids.2013.05.004_b0325","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1152\/ajpendo.00107.2005","article-title":"Postnatal developmental consequences of altered insulin sensitivity in female sheep treated prenatally with testosterone","volume":"289","author":"Recabarren","year":"2005","journal-title":"Am J Physiol (Endocrinol Metab)"},{"key":"10.1016\/j.steroids.2013.05.004_b0330","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1210\/en.2009-1015","article-title":"Developmental programming: impact of prenatal testosterone excess and postnatal weight gain on insulin sensitivity index and transfer of traits to offspring of overweight females","volume":"151","author":"Padmanabhan","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0335","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1210\/jc.85.3.1206","article-title":"Timing of prenatal androgen excess determines differential impairment in insulin secretion and action in adult female rhesus monkeys","volume":"85","author":"Eisner","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0340","doi-asserted-by":"crossref","first-page":"5369","DOI":"10.1210\/en.2007-0305","article-title":"Postnatal testosterone exposure results in insulin resistance, enlarged mesenteric adipocytes, and an atherogenic lipid profile in adult female rats: comparisons with estradiol and dihydrotestosterone","volume":"148","author":"Alexanderson","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0345","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/oby.2003.42","article-title":"Increased adiposity in female rhesus monkeys exposed to androgen excess during early gestation","volume":"11","author":"Eisner","year":"2003","journal-title":"Obes Res"},{"key":"10.1016\/j.steroids.2013.05.004_b0350","doi-asserted-by":"crossref","first-page":"E262","DOI":"10.1152\/ajpendo.90208.2008","article-title":"Transient prenatal androgen exposure produces metabolic syndrome in adult female rats","volume":"295","author":"Demissie","year":"2008","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0355","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1172\/JCI1353","article-title":"Imprinting of female offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats","volume":"101","author":"Nilsson","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.steroids.2013.05.004_b0360","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1210\/en.2012-2145","article-title":"Developmental programming: Impact of prenatal testosterone excess on insulin sensitivity, adiposity and free fatty acid profile in postpubertal female sheep","volume":"154","author":"Veiga-Lopez","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0365","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1093\/humrep\/der070","article-title":"Comparison of MRI-assessed body fat content between lean women with polycystic ovary syndrome (PCOS) and matched controls: less visceral fat with PCOS","volume":"26","author":"Dolfing","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0370","unstructured":"Abbott D.H., Eisner J.R., Goodfriend T.L., Medley R.D., Peterson E.J., Colman R.J., et al. Leptin and total free fatty acids are elevated in the circulation of prenatally androgenized female rhesus monkeys. Paper presented at: Annual Meeting of the Endocrine Society; June 18, 2002; San Francisco, CA. p. 2\u2013329."},{"key":"10.1016\/j.steroids.2013.05.004_b0375","doi-asserted-by":"crossref","first-page":"E1837","DOI":"10.1152\/ajpendo.00668.2006","article-title":"Hypertension caused by prenatal testosterone excess in female sheep","volume":"292","author":"King","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0380","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.siny.2004.03.001","article-title":"Maternal constraint of fetal growth and its consequences","volume":"9","author":"Gluckman","year":"2004","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.steroids.2013.05.004_b0385","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1210\/en.2003-0478","article-title":"Fetal programming: prenatal testosterone excess leads to fetal growth retardation and postnatal catch-up growth in sheep","volume":"145","author":"Manikkam","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2013.05.004_b0390","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1530\/acta.0.1030420","article-title":"Prenatal testosterone propionate and postnatal ovarian activity in the rat","volume":"103","author":"Slob","year":"1983","journal-title":"Acta Endocrinol (Copenh)"},{"key":"10.1016\/j.steroids.2013.05.004_b0395","doi-asserted-by":"crossref","first-page":"3558","DOI":"10.1210\/jc.83.10.3558","article-title":"Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: relation to reduced fetal growth","volume":"83","author":"Ibanez","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0400","first-page":"707","article-title":"Prevalence of metabolic disorders among family members of patients with polycystic ovary syndrome","volume":"129","author":"Benitez","year":"2001","journal-title":"Rev Med Chil"},{"key":"10.1016\/j.steroids.2013.05.004_b0405","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1210\/jc.2009-2651","article-title":"Infants of women with polycystic ovary syndrome have lower cord blood androstenedione and estradiol levels","volume":"95","author":"Anderson","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"issue":"Suppl. 1","key":"10.1016\/j.steroids.2013.05.004_b0410","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/j.fertnstert.2006.03.013","article-title":"Prenatal growth restraint followed by catch-up of weight: a hyperinsulinemic pathway to polycystic ovary syndrome","volume":"86","author":"de Zegher","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.steroids.2013.05.004_b0415","first-page":"355","article-title":"Prenatal exposure of rhesus monkeys to patent androgens: morphological, behavioral, and physiological consequences","volume":"11","author":"Goy","year":"1982","journal-title":"Banbury Rep"},{"key":"10.1016\/j.steroids.2013.05.004_b0420","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1210\/jc.80.10.2966","article-title":"Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism","volume":"80","author":"Apter","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0425","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1210\/jcem-73-3-525","volume":"73","author":"Beck-Peccoz","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0430","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1095\/biolreprod.110.086686","article-title":"Developmental programming: impact of excess prenatal testosterone on intra-uterine fetal endocrine milieu and growth in sheep","volume":"84","author":"Veiga-Lopez","year":"2011","journal-title":"Biol Reprod"},{"key":"10.1016\/j.steroids.2013.05.004_b0435","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1210\/er.2009-0002","article-title":"Endocrine-disrupting chemicals: an endocrine society scientific statement","volume":"30","author":"Diamanti-Kandarakis","year":"2009","journal-title":"Endocr Rev"},{"key":"10.1016\/j.steroids.2013.05.004_b0440","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1210\/jc.2008-2836","article-title":"Metabolic and reproductive features before and during puberty in daughters of women with polycystic ovary syndrome","volume":"94","author":"Sir-Petermann","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.steroids.2013.05.004_b0445","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1210\/en.2010-1219","article-title":"Prenatal androgen exposure leads to alterations in gene and protein expression in the ovine fetal ovary","volume":"152","author":"Hogg","year":"2011","journal-title":"Endocrinology"}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X13001049?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X13001049?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,14]],"date-time":"2019-07-14T00:09:20Z","timestamp":1563062960000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X13001049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":89,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S0039128X13001049"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2013.05.004","relation":{},"ISSN":["0039-128X"],"issn-type":[{"value":"0039-128X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}