{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:27:38Z","timestamp":1765546058128,"version":"3.37.3"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004621","name":"Kerman University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.steroids.2015.12.002","type":"journal-article","created":{"date-parts":[[2015,12,17]],"date-time":"2015-12-17T08:36:37Z","timestamp":1450341397000},"page":"106-112","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The risk of life-threatening ventricular arrhythmias in presence of high-intensity endurance exercise along with chronic administration of nandrolone decanoate"],"prefix":"10.1016","volume":"105","author":[{"given":"Farzane","family":"Abdollahi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyavash","family":"Joukar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Najafipour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdolah","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaser","family":"Masumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fateme","family":"Binayi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0005","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.2147\/VHRM.S4261","article-title":"Anabolic steroids, acute myocardial infarction and polycythemia: a case report and review of the literature","volume":"4","author":"Stergiopoulos","year":"2008","journal-title":"Vasc. Health Risk Manag."},{"issue":"7","key":"10.1016\/j.steroids.2015.12.002_b0010","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1365-2362.2011.02642.x","article-title":"Adverse cardiovascular effects of anabolic steroids: pathophysiology imaging","volume":"42","author":"Golestani","year":"2012","journal-title":"Eur. J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.steroids.2015.12.002_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0033-0620(98)80019-4","article-title":"The cardiac toxicity of anabolic steroids","volume":"41","author":"Sullivan","year":"1998","journal-title":"Prog. Cardiovasc. Dis."},{"key":"10.1016\/j.steroids.2015.12.002_b0020","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1152\/jappl.2001.91.5.2205","article-title":"Short-term exercise improves myocardial tolerance to in vivo ischemia-reperfusion in the rat short-term exercise improves myocardial tolerance to in vivo ischemia-reperfusion in the rat","volume":"91","author":"Demirel","year":"1991","journal-title":"J. Appl. Physiol."},{"issue":"3","key":"10.1016\/j.steroids.2015.12.002_b0025","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0008-6363(02)00334-6","article-title":"Exercise induces early and late myocardial preconditioning in dogs","volume":"55","author":"Domenech","year":"2002","journal-title":"Cardiovasc. Res."},{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0030","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1152\/japplphysiol.00487.2003","article-title":"Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart","volume":"95","author":"Brown","year":"2003","journal-title":"J. Appl. Physiol."},{"issue":"Suppl. 1","key":"10.1016\/j.steroids.2015.12.002_b0035","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S1440-2440(04)80273-1","article-title":"Updating the evidence that physical activity is good for health: an epidemiological review 2000\u20132003","volume":"7","author":"Bauman","year":"2004","journal-title":"J. Sci. Med. Sport"},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0040","first-page":"137","article-title":"Association between anabolic steroids and aerobic physical training leads to cardiac morphological alterations and loss of ventricular function in rats","volume":"17","author":"Do","year":"2011","journal-title":"Rev. Bras. Med. Esporte"},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0045","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s10557-013-6503-8","article-title":"AT1 and aldosterone receptors blockade prevents the chronic effect of nandrolone on the exercise-induced cardioprotection in perfused rat heart subjected to ischemia and reperfusion","volume":"28","author":"Marques-Neto","year":"2014","journal-title":"Cardiovasc. Drugs Ther."},{"issue":"4","key":"10.1016\/j.steroids.2015.12.002_b0050","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1161\/01.HYP.0000174600.51515.e7","article-title":"Vascular sensitivity to phenylephrine in rats submitted to anaerobic training and nandrolone treatment","volume":"46","author":"Cunha","year":"2005","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0055","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1520\/JFS12981J","article-title":"Sudden cardiac death during exercise in a weight lifter using anabolic androgenic steroids: pathological and toxicological findings","volume":"35","author":"Luke","year":"1990","journal-title":"J. Forensic Sci."},{"issue":"1","key":"10.1016\/j.steroids.2015.12.002_b0060","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s00414-005-0055-9","article-title":"Sudden cardiac death during anabolic steroid abuse: morphologic and toxicologic findings in two fatal cases of bodybuilders","volume":"121","author":"Fineschi","year":"2007","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.steroids.2015.12.002_b0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.forsciint.2011.10.032","article-title":"Anabolic androgenic steroids abuse and cardiac death in athletes: morphological and toxicological findings in four fatal cases","volume":"217","author":"Montisci","year":"2012","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.steroids.2015.12.002_b0070","doi-asserted-by":"crossref","DOI":"10.1007\/s12012-015-9320-4","article-title":"The effects of nandrolone decanoate along with prolonged low-intensity exercise on susceptibility to ventricular arrhythmias","author":"Binayi","year":"2015","journal-title":"Cardiovasc. Toxicol."},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0075","first-page":"26233","article-title":"Nandrolone plus moderate exercise increases the susceptibility to lethal arrhythmias","volume":"4","author":"Ghorbani Baravati","year":"2015","journal-title":"Res. Cardiovasc. Med."},{"key":"10.1016\/j.steroids.2015.12.002_b0080","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1176\/ajp.145.4.487","article-title":"Affective and psychotic symptoms associated with anabolic steroid use","volume":"145","author":"Pope","year":"1988","journal-title":"Am. J. Psychiatry"},{"issue":"12","key":"10.1016\/j.steroids.2015.12.002_b0085","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1590\/S0100-879X2004001200018","article-title":"Swimming training increases cardiac vagal activity and induces cardiac hypertrophy in rats","volume":"37","author":"Medeiros","year":"2004","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"8","key":"10.1016\/j.steroids.2015.12.002_b0090","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1016\/j.peptides.2011.06.027","article-title":"Involvement of the atrial natriuretic peptide in the reduction of arterial pressure induced by swimming but not by running training in hypertensive rats","volume":"32","author":"Endlich","year":"2011","journal-title":"Peptides"},{"issue":"12","key":"10.1016\/j.steroids.2015.12.002_b0095","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.sleep.2013.07.008","article-title":"Susceptibility to life-threatening ventricular arrhythmias in an animal model of paradoxical sleep deprivation","volume":"14","author":"Joukar","year":"2013","journal-title":"Sleep Med."},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0100","doi-asserted-by":"crossref","first-page":"e27013","DOI":"10.5812\/cardiovascmed.4(2)2015.27013","article-title":"Evaluation of Melissa officinalis (lemon balm) effects on heart electrical system","volume":"4","author":"Joukar","year":"2015","journal-title":"Res. Cardiovasc. Med."},{"issue":"7","key":"10.1016\/j.steroids.2015.12.002_b0105","doi-asserted-by":"crossref","first-page":"836","DOI":"10.3109\/13880209.2013.767362","article-title":"Protective effects of saffron (Crocus sativus) against lethal ventricular arrhythmias induced by heart reperfusion in rat: a potential anti-arrhythmic agent","volume":"51","author":"Joukar","year":"2013","journal-title":"Pharm. Biol."},{"issue":"4","key":"10.1016\/j.steroids.2015.12.002_b0110","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1159\/000363452","article-title":"Efficacy of Melissa officinalis in suppressing ventricular arrhythmias following ischemia-reperfusion of the heart: a comparison with amiodarone","volume":"23","author":"Joukar","year":"2014","journal-title":"Med. Princ. Pract."},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0115","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.pharmthera.2013.04.008","article-title":"The lambeth conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias","volume":"139","author":"Curtis","year":"2013","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.steroids.2015.12.002_b0120","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.01251.2006","article-title":"Anabolic steroids induce cardiac renin-angiotensin system and impair the beneficial effects of aerobic training in rats","volume":"293","author":"Rocha","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.steroids.2015.12.002_b0125","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.steroids.2015.12.002_b0130","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.steroids.2015.12.002_b0135","first-page":"309","article-title":"Ameliorative effect of black tea on nicotine induced cardiovascular pathogenesis in rat","volume":"11","author":"Joukar","year":"2012","journal-title":"EXCLI J."},{"issue":"3","key":"10.1016\/j.steroids.2015.12.002_b0140","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0009-9120(96)00003-6","article-title":"A simplified method for the analysis of hydroxyproline in biological tissues","volume":"29","author":"Reddy","year":"1996","journal-title":"Clin. Biochem."},{"issue":"4","key":"10.1016\/j.steroids.2015.12.002_b0145","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1152\/jappl.1995.78.4.1303","article-title":"Exercise-induced cardiac hypertrophy is associated with an increased myocardial compliance","volume":"78","author":"Woodiwiss","year":"1995","journal-title":"J. Appl. Physiol."},{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0150","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1590\/S1517-86922011000600011","article-title":"Nandrolone deaconate increases the left ventricular wall but attenuates the cavity increase caused by swimming training in rats","volume":"17","author":"Soares","year":"2011","journal-title":"Rev. Bras. Med. Esporte"},{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0155","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.phrs.2009.03.001","article-title":"Long-term treatment with supraphysiological doses of nandrolone decanoate reduces the sensitivity of Bezold\u2013Jarisch reflex control of heart rate and blood pressure","volume":"59","author":"Bissoli","year":"2009","journal-title":"Pharmacol. Res."},{"issue":"3","key":"10.1016\/j.steroids.2015.12.002_b0160","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s00395-010-0143-y","article-title":"Ischemia\/reperfusion injury is increased and cardioprotection by a postconditioning protocol is lost as cardiac hypertrophy develops in nandrolone treated rats","volume":"106","author":"Penna","year":"2011","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.steroids.2015.12.002_b0165","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.steroids.2012.12.009","article-title":"Nandrolone decanoate determines cardiac remodelling and injury by an imbalance in cardiac inflammatory cytokines and ACE activity, blunting of the Bezold\u2013Jarisch reflex, resulting in the development of hypertension","volume":"78","author":"Franquni","year":"2013","journal-title":"Steroids"},{"issue":"10","key":"10.1016\/j.steroids.2015.12.002_b0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0046114","article-title":"Effects of aerobic exercise training on cardiac Renin\u2013Angiotensin system in an obese zucker rat strain","volume":"7","author":"Barretti","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0175","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1161\/HYPERTENSIONAHA.110.168252","article-title":"Aerobic exercise training-induced left ventricular hypertrophy involves regulatory MicroRNAs, decreased angiotensin-converting enzyme-angiotensin II, and synergistic regulation of angiotensin-converting enzyme 2-angiotensin (1\u20137)","volume":"58","author":"Fernandes","year":"2011","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.steroids.2015.12.002_b0180","first-page":"21","article-title":"Proposed mechanisms for the anabolic steroid-induced increase in myocardial susceptibility to ischaemia\/reperfusion injury","volume":"16","author":"Du Toit","year":"2005","journal-title":"Cardiovasc. J. S. Afr."},{"key":"10.1016\/j.steroids.2015.12.002_b0185","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/978-3-540-79088-4_18","article-title":"Androgenic anabolic steroid abuse and the cardiovascular system","volume":"195","author":"Vanberg","year":"2010","journal-title":"Handb. Exp. Pharmacol."},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0190","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/apha.12093","article-title":"Chronic, supra-physiological doses of nandrolone decanoate and exercise induced cardio-toxicity in an animal-model study","volume":"208","author":"Fineschi","year":"2013","journal-title":"Acta Physiol."},{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0195","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1161\/01.CIR.83.6.1849","article-title":"Pathological hypertrophy and cardiac interstitium. Fibrosis and renin\u2013angiotensin\u2013aldosterone system","volume":"83","author":"Weber","year":"1991","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.steroids.2015.12.002_b0200","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.taap.2014.06.031","article-title":"Chronic nandrolone administration promotes oxidative stress, induction of pro-inflammatory cytokine and TNF-\u03b1 mediated apoptosis in the kidneys of CD1 treated mice","volume":"280","author":"Riezzo","year":"2014","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.steroids.2015.12.002_b0205","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/s12012-011-9105-3","article-title":"High-dose testosterone propionate treatment reverses the effects of endurance training on myocardial antioxidant defenses in adolescent male rats","volume":"11","author":"Sadowska-Kr\u0229pa","year":"2011","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.steroids.2015.12.002_b0210","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jsbmb.2013.06.006","article-title":"Exercise-induced cardioprotection is impaired by anabolic steroid treatment through a redox-dependent mechanism","volume":"138","author":"Chaves","year":"2013","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.steroids.2015.12.002_b0215","article-title":"The effects of chronic administration of nandrolone decanoate on redox status in exercised rats","author":"Nikolic","year":"2015","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.steroids.2015.12.002_b0220","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1590\/S0100-879X2011007500043","article-title":"Vascular adaptive responses to physical exercise and to stress are affected differently by nandrolone administration","volume":"44","author":"Bruder-Nascimento","year":"2011","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.steroids.2015.12.002_b0225","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.lfs.2011.05.004","article-title":"The renin-angiotensin system is modulated by swimming training depending on the age of spontaneously hypertensive rats","volume":"89","author":"Zamo","year":"2011","journal-title":"Life Sci."},{"issue":"6","key":"10.1016\/j.steroids.2015.12.002_b0230","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.amjcard.2010.05.013","article-title":"Cardiac and metabolic effects of anabolic-androgenic steroid abuse on lipids, blood pressure, left ventricular dimensions, and rhythm","volume":"106","author":"Achar","year":"2010","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.steroids.2015.12.002_b0235","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1093\/toxsci\/kfm186","article-title":"Nandrolone potentiates arrhythmogenic effects of cardiac ischemia in the Rat","volume":"99","author":"Phillis","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.steroids.2015.12.002_b0240","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1053\/euhj.2001.2802","article-title":"Long-lasting sport practice and lone atrial fibrillation","volume":"23","author":"Mont","year":"2002","journal-title":"Eur. Heart J."},{"issue":"5","key":"10.1016\/j.steroids.2015.12.002_b0245","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1113\/eph8802619","article-title":"Exercise-induced cardiac hypertrophy: a substrate for sudden death in athletes?","volume":"88","author":"Hart","year":"2003","journal-title":"Exp. Physiol."},{"issue":"2","key":"10.1016\/j.steroids.2015.12.002_b0250","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1152\/physrev.00042.2006","article-title":"Catecholaminergic systems in stress: structural and molecular genetic approaches","volume":"89","author":"Kvetnansky","year":"2009","journal-title":"Physiol. Rev."},{"issue":"8","key":"10.1016\/j.steroids.2015.12.002_b0255","doi-asserted-by":"crossref","first-page":"3586","DOI":"10.1210\/en.2002-0164","article-title":"Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells","volume":"144","author":"Estrada","year":"2003","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.steroids.2015.12.002_b0260","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1161\/CIRCEP.112.976787","article-title":"Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death","volume":"6","author":"Sovari","year":"2013","journal-title":"Circ. Arrhythm. Electrophysiol."}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X15003001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X15003001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,4,5]],"date-time":"2021-04-05T22:24:27Z","timestamp":1617661467000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X15003001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":52,"alternative-id":["S0039128X15003001"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2015.12.002","relation":{},"ISSN":["0039-128X"],"issn-type":[{"type":"print","value":"0039-128X"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The risk of life-threatening ventricular arrhythmias in presence of high-intensity endurance exercise along with chronic administration of nandrolone decanoate","name":"articletitle","label":"Article Title"},{"value":"Steroids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.steroids.2015.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}