{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T21:33:15Z","timestamp":1778535195511,"version":"3.51.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research","doi-asserted-by":"publisher","award":["19-515-04009"],"award-info":[{"award-number":["19-515-04009"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["19-15-00245"],"award-info":[{"award-number":["19-15-00245"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007595","name":"Belarusian Republican Foundation for Fundamental Research","doi-asserted-by":"publisher","award":["X19PM-074"],"award-info":[{"award-number":["X19PM-074"]}],"id":[{"id":"10.13039\/100007595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001794","name":"University of Queensland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.steroids.2022.109135","type":"journal-article","created":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T03:30:44Z","timestamp":1667446244000},"page":"109135","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Synthesis and biological activity of 21,22-cyclosteroids and their derivatives"],"prefix":"10.1016","volume":"188","author":[{"given":"Maryia V.","family":"Barysevich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marharyta V.","family":"Laktsevich-Iskryk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander M.","family":"Scherbakov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana I.","family":"Salnikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga E.","family":"Andreeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danila V.","family":"Sorokin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri Y.","family":"Shchegolev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaksiej L.","family":"Hurski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir N.","family":"Zhabinskii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir A.","family":"Khripach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.steroids.2022.109135_b0005","doi-asserted-by":"crossref","unstructured":"A.V. Zolottsev, A. Latysheva, S., V.S. Pokrovsky, I.I. Khan, A.Y. Misharin, Promising applications of steroid conjugates for cancer research and treatment, Eur. J. Med. Chem. 210 (2021) 113089. 10.1016\/j.ejmech.2020.113089.","DOI":"10.1016\/j.ejmech.2020.113089"},{"issue":"14","key":"10.1016\/j.steroids.2022.109135_b0010","doi-asserted-by":"crossref","first-page":"6986","DOI":"10.1021\/cr4002935","article-title":"Man-made cytotoxic steroids: exemplary agents for cancer therapy","volume":"114","author":"Bansal","year":"2014","journal-title":"Chem. Rev."},{"key":"10.1016\/j.steroids.2022.109135_b0015","doi-asserted-by":"crossref","unstructured":"J.A. Salvador, J.F. Carvalho, M.A. Neves, S.M. Silvestre, A.J. Leitao, M.M. Silva, M.L. Sa e Melo, Anticancer steroids: linking natural and semi-synthetic compounds, Nat. Prod. Rep. 30(2) (2013) 324-374. 10.1039\/c2np20082a.","DOI":"10.1039\/C2NP20082A"},{"key":"10.1016\/j.steroids.2022.109135_b0020","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jsbmb.2013.05.011","article-title":"Current status on development of steroids as anticancer agents","volume":"137","author":"Gupta","year":"2013","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.steroids.2022.109135_b0025","unstructured":"V.A. Khripach, V.N. Zhabinskii, A. de Groot, Brassinosteroids. A New Class of Plant Hormones, Academic Press, San Diego, 1999. 10.1016\/B978-0-12-406360-0.X5000-X."},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0030","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1152\/physrev.2000.80.1.361","article-title":"Oxysterols: Modulators of cholesterol metabolism and other processes","volume":"80","author":"Schroepfer","year":"2000","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0035","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bcp.2013.02.029","article-title":"Oxysterols in cancer cell proliferation and death","volume":"86","author":"de Weille","year":"2013","journal-title":"Biochem. Pharmacol."},{"issue":"5","key":"10.1016\/j.steroids.2022.109135_b0040","first-page":"497","article-title":"Biological activity of phytosterols and their derivatives","volume":"53","author":"Mehtiev","year":"2007","journal-title":"Biomeditsinskaya Khimiya"},{"issue":"2","key":"10.1016\/j.steroids.2022.109135_b0045","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.phytochem.2007.07.028","article-title":"Anticancer and antiproliferative activity of natural brassinosteroids","volume":"69","author":"Mal\u00edkov\u00e1","year":"2008","journal-title":"Phytochemistry"},{"key":"10.1016\/j.steroids.2022.109135_b0050","series-title":"Brassinosteroids: Practical Applications in Agriculture and Human Health","first-page":"84","article-title":"Anticancer Activities of Brassinosteroids","author":"Hoffmannov\u00e1","year":"2012"},{"key":"10.1016\/j.steroids.2022.109135_b0055","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.steroids.2014.08.025","article-title":"Steroid plant hormones: effects outside plant kingdom","volume":"97","author":"Zhabinskii","year":"2015","journal-title":"Steroids"},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0060","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1134\/S1068162010060117","article-title":"Synthesis of secasterol and 24-episecasterol and their toxicity for MCF-7 cells","volume":"36","author":"Khripach","year":"2010","journal-title":"Russ. J. Bioorg. Chem."},{"key":"10.1016\/j.steroids.2022.109135_b0065","series-title":"Brassinosteroids: Plant Growth and Development","first-page":"389","article-title":"Anticancer potential of brassinosteroids","author":"Panibrat","year":"2019"},{"issue":"3","key":"10.1016\/j.steroids.2022.109135_b0070","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.steroids.2010.01.006","article-title":"Toxicity of (22R,23R)-22,23-dihydroxystigmastane derivatives to cultured cancer cells","volume":"75","author":"Misharin","year":"2010","journal-title":"Steroids"},{"issue":"4","key":"10.1016\/j.steroids.2022.109135_b0075","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1134\/S1068162012040097","article-title":"Synthesis and biological activity of the probable biosynthetic precursors of 241 norbrassinolide","volume":"38","author":"Khripach","year":"2012","journal-title":"Russ. J. Bioorg. Chem."},{"key":"10.1016\/j.steroids.2022.109135_b0080","doi-asserted-by":"crossref","first-page":"e1900332","DOI":"10.1002\/cbdv.201900332","article-title":"Biological evaluation of a new brassinosteroid: antiproliferative effects and targeting estrogen receptor \u03b1 pathways","volume":"16","author":"Scherbakov","year":"2019","journal-title":"Chemistry & Biodiversity"},{"issue":"22","key":"10.1016\/j.steroids.2022.109135_b0085","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.1039\/C8CC00888D","article-title":"Stereoselective synthesis of \u03b1-methyl and \u03b1-alkyl ketones from esters and alkenes via cyclopropanol intermediates","volume":"54","author":"Barysevich","year":"2018","journal-title":"Chem Commun"},{"key":"10.1016\/j.steroids.2022.109135_b0090","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1002\/ejoc.202000094","article-title":"Visible-light-promoted catalytic ring-opening isomerization of 1,2-disubstituted cyclopropanols to linear ketones","volume":"16","author":"Laktsevich-Iskryk","year":"2020","journal-title":"Eur. J. Org. Chem."},{"issue":"7","key":"10.1016\/j.steroids.2022.109135_b0095","first-page":"747","article-title":"The tetrazolium dye assay for rapid in vitro assessment of cytotoxicity","volume":"39","author":"Iselt","year":"1989","journal-title":"Arzneimittelforschung."},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0100","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/toxsci\/66.1.82","article-title":"Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and\/or hAR for endocrine screening","volume":"66","author":"Hartig","year":"2002","journal-title":"Toxicol. Sci."},{"issue":"2","key":"10.1016\/j.steroids.2022.109135_b0105","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1021\/jo01037a505","article-title":"The solvolysis of stigmasteryl tosylate","volume":"28","author":"Steele","year":"1963","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.steroids.2022.109135_b0110","first-page":"1584","article-title":"A synthesis of the insect moulting hormone, ecdysone, and related compounds","volume":"C (11)","author":"Barton","year":"1970","journal-title":"J. Chem. Soc."},{"key":"10.1016\/j.steroids.2022.109135_b0115","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0039-128X(85)90020-0","article-title":"A convenient isomerization of 6-oxo-3\u03b1,5-cyclo-5\u03b1-steroids to 6-oxo-\u03942-5\u03b1-steroids","volume":"45","author":"Anastasia","year":"1985","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2022.109135_b0120","series-title":"Cyclopropanes in Organic Synthesis","author":"Kulinkovich","year":"2015"},{"issue":"38","key":"10.1016\/j.steroids.2022.109135_b0125","doi-asserted-by":"crossref","first-page":"7649","DOI":"10.1039\/c2ob26082d","article-title":"The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis","volume":"10","author":"Haym","year":"2012","journal-title":"Org. Biomol. Chem."},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0130","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/ejoc.201801312","article-title":"Modern developments in the chemistry of homoenolates","volume":"2019","author":"Mills","year":"2019","journal-title":"Eur. J. Org. Chem."},{"issue":"12","key":"10.1016\/j.steroids.2022.109135_b0135","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1055\/s-0035-1560442","article-title":"Transition-metal-catalyzed C-C and C\u2013X bond-forming reactions using cyclopropanols","volume":"48","author":"Nikolaev","year":"2016","journal-title":"Synthesis"},{"issue":"2","key":"10.1016\/j.steroids.2022.109135_b0140","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1021\/ol991250r","article-title":"Palladium-mediated ring opening of hydroxycyclopropanes","volume":"2","author":"Park","year":"2000","journal-title":"Org. Lett."},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0145","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1055\/s-0040-1706088","article-title":"Photocatalytic oxidant-free synthesis of linear unsaturated ketones from 1,2-disubstituted cyclopropanols","volume":"53","author":"Laktsevich-Iskryk","year":"2021","journal-title":"Synthesis"},{"issue":"3","key":"10.1016\/j.steroids.2022.109135_b0150","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1139\/v87-114","article-title":"An improved route to pregna-5,20-dien-3\u03b2-ol (muricin aglycone): carbon and proton nuclear magnetic resonance assignments for the aglycon and a number of related pregnene derivatives","volume":"65","author":"Dawe","year":"1987","journal-title":"Can. J. Chem."},{"issue":"3","key":"10.1016\/j.steroids.2022.109135_b0155","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1021\/cr60313a002","article-title":"Various approaches to the construction of aliphatic side chains of steroids and related compounds","volume":"78","author":"Piatak","year":"1978","journal-title":"Chem. Rev."},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0160","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s00210-019-01622-5","article-title":"Abiraterone acetate exerts a cytotoxic effect in human prostate cancer cell lines","volume":"392","author":"Fragni","year":"2019","journal-title":"Naunyn. Schmiedebergs Arch. Pharmacol."},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0165","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.4103\/jcrt.JCRT_677_19","article-title":"Increased breast cancer cell sensitivity to cisplatin using a novel small molecule inhibitor","volume":"16","author":"Hatzidaki","year":"2020","journal-title":"J Cancer Res Ther"},{"issue":"7","key":"10.1016\/j.steroids.2022.109135_b0170","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s11626-999-0115-4","article-title":"A new human prostate carcinoma cell line, 22Rv1","volume":"35","author":"Sramkoski","year":"1999","journal-title":"In Vitro Cell. Dev. Biol. Anim."},{"key":"10.1016\/j.steroids.2022.109135_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103142","article-title":"Novel steroidal 1,3,4-thiadiazines: Synthesis and biological evaluation in androgen receptor-positive prostate cancer 22Rv1 cells","volume":"91","author":"Komendantova","year":"2019","journal-title":"Bioorg. Chem."},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0180","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1365-2605.2009.01030.x","article-title":"Androgen-responsive and -unresponsive prostate cancer cell lines respond differently to stimuli inducing neuroendocrine differentiation","volume":"33","author":"Marchiani","year":"2010","journal-title":"Int. J. Androl."},{"issue":"11","key":"10.1016\/j.steroids.2022.109135_b0185","doi-asserted-by":"crossref","first-page":"18550","DOI":"10.18632\/oncotarget.14537","article-title":"Androgen receptor splice variants and prostate cancer: From bench to bedside","volume":"8","author":"Wadosky","year":"2017","journal-title":"Oncotarget"},{"issue":"19","key":"10.1016\/j.steroids.2022.109135_b0190","doi-asserted-by":"crossref","first-page":"4105","DOI":"10.1021\/bi102059z","article-title":"Mechanism of androgen receptor antagonism by bicalutamide in the treatment of prostate cancer","volume":"50","author":"Osguthorpe","year":"2011","journal-title":"Biochemistry"},{"issue":"3","key":"10.1016\/j.steroids.2022.109135_b0195","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s12033-013-9672-6","article-title":"A defined methodology for reliable quantification of Western blot data","volume":"55","author":"Taylor","year":"2013","journal-title":"Mol. Biotechnol."},{"issue":"4","key":"10.1016\/j.steroids.2022.109135_b0200","doi-asserted-by":"crossref","first-page":"161.e19","DOI":"10.1016\/j.urolonc.2017.11.001","article-title":"Overexpression of nuclear AR-V7 protein in primary prostate cancer is an independent negative prognostic marker in men with high-risk disease receiving adjuvant therapy","volume":"36","author":"Chen","year":"2018","journal-title":"Urol. Oncol."},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clgc.2019.09.015","article-title":"Androgen receptor splice variant, AR-V7, as a biomarker of resistance to androgen axis-targeted therapies in advanced prostate cancer","volume":"18","author":"Zhang","year":"2020","journal-title":"Clin. Genitourin. Cancer"},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0210","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1158\/0008-5472.CAN-08-2764","article-title":"Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer","volume":"69","author":"Hu","year":"2009","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.steroids.2022.109135_b0215","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s12672-014-0177-y","article-title":"The link between androgen receptor splice variants and castration-resistant prostate cancer","volume":"5","author":"Sprenger","year":"2014","journal-title":"Horm Cancer"},{"key":"10.1016\/j.steroids.2022.109135_b0220","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.canlet.2020.12.037","article-title":"Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy","volume":"504","author":"Ma","year":"2021","journal-title":"Cancer Lett."},{"issue":"43","key":"10.1016\/j.steroids.2022.109135_b0225","doi-asserted-by":"crossref","first-page":"41998","DOI":"10.1074\/jbc.M302460200","article-title":"Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor","volume":"278","author":"Saporita","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.steroids.2022.109135_b0230","first-page":"178","article-title":"Decoding the androgen receptor splice variants","volume":"2","author":"Lu","year":"2013","journal-title":"Transl. Androl. Urol."},{"issue":"1","key":"10.1016\/j.steroids.2022.109135_b0235","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1172\/JCI122819","article-title":"Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer","volume":"129","author":"Sharp","year":"2019","journal-title":"J. Clin. Invest."},{"issue":"14","key":"10.1016\/j.steroids.2022.109135_b0240","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1158\/1078-0432.CCR-20-3471","article-title":"Circulating tumor cell chromosomal instability and neuroendocrine phenotype by immunomorphology and poor outcomes in men with mCRPC treated with abiraterone or enzalutamide","volume":"27","author":"Brown","year":"2021","journal-title":"Clin. Cancer Res."},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0245","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.3390\/cancers13061483","article-title":"Cross-resistance to abiraterone and enzalutamide in castration resistance prostate cancer cellular models is mediated by AR transcriptional reactivation","volume":"13","author":"Simon","year":"2021","journal-title":"Cancers"},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0250","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1158\/1078-0432.CCR-18-0320","article-title":"Expression of AR-V7 and ARv(567es) in circulating tumor cells correlates with outcomes to taxane therapy in men with metastatic prostate cancer treated in TAXYNERGY","volume":"25","author":"Tagawa","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"3","key":"10.1016\/j.steroids.2022.109135_b0255","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/pros.10290","article-title":"Molecular characterization of human prostate carcinoma cell lines","volume":"57","author":"van Bokhoven","year":"2003","journal-title":"Prostate."},{"key":"10.1016\/j.steroids.2022.109135_b0260","unstructured":"BCL2 Gene (Protein Coding). https:\/\/www.genecards.org\/cgi-bin\/carddisp.pl?gene=BCL2&keywords=bcl2. (Accessed May 5, 2022)."},{"issue":"6","key":"10.1016\/j.steroids.2022.109135_b0265","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.3390\/cancers13061292","article-title":"Targeting BCL-2 in cancer: advances, challenges, and perspectives","volume":"13","author":"Hafezi","year":"2021","journal-title":"Cancers"},{"issue":"11","key":"10.1016\/j.steroids.2022.109135_b0270","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1002\/pros.23843","article-title":"Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide","volume":"79","author":"Pilling","year":"2019","journal-title":"Prostate"},{"issue":"2","key":"10.1016\/j.steroids.2022.109135_b0275","first-page":"105","article-title":"Enhanced control of proliferation in telomerized cells","volume":"38","author":"Egorov","year":"2007","journal-title":"Ontogenez"}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X2200174X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X2200174X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T10:10:32Z","timestamp":1758535832000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X2200174X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":55,"alternative-id":["S0039128X2200174X"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2022.109135","relation":{},"ISSN":["0039-128X"],"issn-type":[{"value":"0039-128X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis and biological activity of 21,22-cyclosteroids and their derivatives","name":"articletitle","label":"Article Title"},{"value":"Steroids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.steroids.2022.109135","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109135"}}