{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:32:11Z","timestamp":1792585931183,"version":"4.5.0"},"reference-count":87,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T00:00:00Z","timestamp":1689033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.steroids.2023.109271","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T11:20:28Z","timestamp":1689074428000},"page":"109271","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Genomic signaling of vitamin D"],"prefix":"10.1016","volume":"198","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2633-0684","authenticated-orcid":false,"given":"Carsten","family":"Carlberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0005","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3390\/nu15010171","article-title":"A pleiotropic nuclear hormone labelled hundred years ago vitamin D","volume":"15","author":"Carlberg","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.steroids.2023.109271_b0010","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0021-9258(18)85783-0","article-title":"Studies on experimental rickets: An experimental demonstration of the existence of a vitamin which promotes calcium deposition","volume":"52","author":"McMollum","year":"1922","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0015","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/1523-1747.ep12479237","article-title":"The cutaneous photosynthesis of previtamin D3: A unique photoendocrine system","volume":"77","author":"Holick","year":"1981","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.steroids.2023.109271_b0020","doi-asserted-by":"crossref","first-page":"248","DOI":"10.3389\/fphys.2014.00248","article-title":"Vitamin D: A critical and essential micronutrient for human health","volume":"5","author":"Bendik","year":"2014","journal-title":"Front Physiol"},{"issue":"2","key":"10.1016\/j.steroids.2023.109271_b0025","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/jcb.10338","article-title":"Vitamin D: A millenium perspective","volume":"88","author":"Holick","year":"2003","journal-title":"J Cell Biochem"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0030","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4161\/derm.24494","article-title":"Sunlight and vitamin D: A global perspective for health","volume":"5","author":"Wacker","year":"2013","journal-title":"Dermato-endocrinology"},{"issue":"6 Suppl","key":"10.1016\/j.steroids.2023.109271_b0035","doi-asserted-by":"crossref","first-page":"1678S","DOI":"10.1093\/ajcn\/80.6.1678S","article-title":"Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease","volume":"80","author":"Holick","year":"2004","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1016\/j.steroids.2023.109271_b0040","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.1210\/en.2002-221101","article-title":"Cloning of a functional vitamin D receptor from the lamprey (Petromyzon marinus), an ancient vertebrate lacking a calcified skeleton and teeth","volume":"144","author":"Whitfield","year":"2003","journal-title":"Endocrinology"},{"issue":"7","key":"10.1016\/j.steroids.2023.109271_b0045","doi-asserted-by":"crossref","first-page":"5821","DOI":"10.1021\/acs.jmedchem.2c00171","article-title":"Advances in vitamin D receptor function and evolution based on the 3D structure of the Lamprey ligand-binding domain","volume":"65","author":"Sigueiro","year":"2022","journal-title":"J Med Chem"},{"key":"10.1016\/j.steroids.2023.109271_b0050","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1097-2765(00)80413-X","article-title":"Crystal structure of the nuclear receptor for vitamin D bound to its natural ligand","volume":"5","author":"Rochel","year":"2000","journal-title":"Mol Cell"},{"issue":"4","key":"10.1016\/j.steroids.2023.109271_b0055","doi-asserted-by":"crossref","first-page":"e0122853","DOI":"10.1371\/journal.pone.0122853","article-title":"Molecular cloning, functional characterization, and evolutionary analysis of vitamin D receptors isolated from basal vertebrates","volume":"10","author":"Kollitz","year":"2015","journal-title":"PLoS ONE"},{"issue":"12","key":"10.1016\/j.steroids.2023.109271_b0060","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.1210\/en.2014-1505","article-title":"Functional diversification of vitamin D receptor paralogs in teleost fish after a whole genome duplication event","volume":"155","author":"Kollitz","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.steroids.2023.109271_b0065","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/bonekey.2013.214","article-title":"Vitamin D: Calcium and bone homeostasis during evolution","volume":"3","author":"Bouillon","year":"2014","journal-title":"BoneKEy Reports"},{"issue":"Pt A","key":"10.1016\/j.steroids.2023.109271_b0070","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jsbmb.2013.10.012","article-title":"The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions","volume":"144","author":"Slominski","year":"2014","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"22","key":"10.1016\/j.steroids.2023.109271_b0075","doi-asserted-by":"crossref","first-page":"4779","DOI":"10.3390\/nu14224779","article-title":"Novel CYP11A1-derived vitamin D and lumisterol biometabolites for the management of COVID-19","volume":"14","author":"Qayyum","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.steroids.2023.109271_b0080","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3389\/fphys.2014.00137","article-title":"Vitamin D and gene networks in human osteoblasts","volume":"5","author":"van de Peppel","year":"2014","journal-title":"Front Physiol"},{"issue":"8","key":"10.1016\/j.steroids.2023.109271_b0085","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1172\/JCI29449","article-title":"Resurrection of vitamin D deficiency and rickets","volume":"116","author":"Holick","year":"2006","journal-title":"J. Clin. Invest."},{"issue":"38","key":"10.1016\/j.steroids.2023.109271_b0090","doi-asserted-by":"crossref","first-page":"15449","DOI":"10.1073\/pnas.1200072109","article-title":"Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment","volume":"109","author":"Coussens","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"21","key":"10.1016\/j.steroids.2023.109271_b0095","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1212\/WNL.0b013e3182752ea8","article-title":"Vitamin D as a protective factor in multiple sclerosis","volume":"79","author":"Salzer","year":"2012","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0100","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1042\/BJ20110744","article-title":"Vitamin D and cancer: A review of molecular mechanisms","volume":"441","author":"Fleet","year":"2012","journal-title":"Biochem J"},{"issue":"7","key":"10.1016\/j.steroids.2023.109271_b0105","doi-asserted-by":"crossref","DOI":"10.3390\/nu14071354","article-title":"Vitamin D and is target genes","volume":"14","author":"Carlberg","year":"2022","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.steroids.2023.109271_b0110","doi-asserted-by":"crossref","first-page":"911","DOI":"10.3390\/ijms23020911","article-title":"Time-resolved gene expression analysis monitors the regulation of inflammatory mediators and attenuation of adaptive immune response by vitamin D","volume":"23","author":"Hanel","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"4","key":"10.1016\/j.steroids.2023.109271_b0115","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3109\/10408363.2010.536429","article-title":"Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors","volume":"47","author":"Fleet","year":"2010","journal-title":"Crit Rev Clin Lab Sci"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0120","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nrd1283","article-title":"Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model","volume":"3","author":"Norman","year":"2004","journal-title":"Nat Rev Drug Discov"},{"issue":"8","key":"10.1016\/j.steroids.2023.109271_b0125","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqab107","article-title":"The interface of nuclear and membrane steroid signaling","volume":"162","author":"Trevino","year":"2021","journal-title":"Endocrinology"},{"issue":"1\u20132","key":"10.1016\/j.steroids.2023.109271_b0130","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.mce.2010.10.017","article-title":"Origin and evolution of the ligand-binding ability of nuclear receptors","volume":"334","author":"Markov","year":"2011","journal-title":"Mol Cell Endocrinol"},{"issue":"3","key":"10.1016\/j.steroids.2023.109271_b0135","doi-asserted-by":"crossref","first-page":"T115","DOI":"10.1530\/JME-13-0212","article-title":"The orphan nuclear receptors at their 25-year reunion","volume":"51","author":"Mullican","year":"2013","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.steroids.2023.109271_b0140","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1042\/bse0400011","article-title":"The evolution of the nuclear receptor superfamily","volume":"40","author":"McEwan","year":"2004","journal-title":"Essays Biochem"},{"issue":"1\u20132","key":"10.1016\/j.steroids.2023.109271_b0145","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.mce.2010.06.016","article-title":"Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR","volume":"334","author":"Krasowski","year":"2011","journal-title":"Mol Cell Endocrinol"},{"issue":"5571","key":"10.1016\/j.steroids.2023.109271_b0150","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1126\/science.1070477","article-title":"Vitamin D receptor as an intestinal bile acid sensor","volume":"296","author":"Makishima","year":"2002","journal-title":"Science"},{"issue":"5418","key":"10.1016\/j.steroids.2023.109271_b0155","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1126\/science.284.5418.1362","article-title":"Identification of a nuclear receptor for bile acids","volume":"284","author":"Makishima","year":"1999","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.steroids.2023.109271_b0160","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.1073\/pnas.051551698","article-title":"The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity","volume":"98","author":"Staudinger","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"46","key":"10.1016\/j.steroids.2023.109271_b0165","doi-asserted-by":"crossref","first-page":"45062","DOI":"10.1074\/jbc.M307145200","article-title":"Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity","volume":"278","author":"Guo","year":"2003","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.steroids.2023.109271_b0170","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1210\/me.2005-0046","article-title":"The nuclear receptor superfamily: A rosetta stone for physiology","volume":"19","author":"Evans","year":"2005","journal-title":"Mol Endocrinol"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0175","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nsb0196-87","article-title":"A canonical structure for the ligand-binding domain of nuclear receptors","volume":"3","author":"Wurtz","year":"1996","journal-title":"Nat Struct Biol"},{"key":"10.1016\/j.steroids.2023.109271_b0180","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1242\/jcs.00247","article-title":"The nuclear receptor superfamily","volume":"116","author":"Robinson-Rechavi","year":"2003","journal-title":"J Cell Sci"},{"issue":"1-2","key":"10.1016\/j.steroids.2023.109271_b0185","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.cell.2017.12.006","article-title":"A map of protein-metabolite interactions reveals principles of chemical communication","volume":"172","author":"Piazza","year":"2018","journal-title":"Cell 172(1\u20132)"},{"issue":"2","key":"10.1016\/j.steroids.2023.109271_b0190","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jmb.2009.11.057","article-title":"Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism","volume":"396","author":"Annalora","year":"2010","journal-title":"J Mol Biol"},{"key":"10.1016\/j.steroids.2023.109271_b0195","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1042\/bj3470321","article-title":"Regulation of cytochrome P450 (CYP) genes by nuclear receptors","volume":"347","author":"Honkakoski","year":"2000","journal-title":"Biochem J"},{"key":"10.1016\/j.steroids.2023.109271_b0200","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1126\/science.294.5548.1866","article-title":"Nuclear receptors and lipid physiology: Opening the X-files","volume":"294","author":"Chawla","year":"2001","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.steroids.2023.109271_b0205","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1093\/nar\/gkm179","article-title":"Selective use of multiple vitamin D response elements underlies the 1\u03b1,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene","volume":"35","author":"Turunen","year":"2007","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0210","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1194\/jlr.R031534","article-title":"Cytochrome P450-mediated metabolism of vitamin D","volume":"55","author":"Jones","year":"2014","journal-title":"J Lipid Res"},{"issue":"10","key":"10.1016\/j.steroids.2023.109271_b0215","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0165-6147(00)01548-0","article-title":"Nuclear receptor ligand-binding domains: Three-dimensional structures, molecular interactions and pharmacological implications","volume":"21","author":"Bourguet","year":"2000","journal-title":"Trends Pharmacol Sci"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0220","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev-physiol-021909-135917","article-title":"Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics","volume":"72","author":"Huang","year":"2010","journal-title":"Annu Rev Physiol"},{"issue":"15","key":"10.1016\/j.steroids.2023.109271_b0225","doi-asserted-by":"crossref","first-page":"10516","DOI":"10.1074\/jbc.M513609200","article-title":"Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket","volume":"281","author":"Moln\u00e1r","year":"2006","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.steroids.2023.109271_b0230","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1517\/13543776.2012.673590","article-title":"Vitamin D receptor ligands: The impact of crystal structures","volume":"22","author":"Carlberg","year":"2012","journal-title":"Expert Opin Ther Pat"},{"issue":"Suppl","key":"10.1016\/j.steroids.2023.109271_b0235","first-page":"S57","article-title":"The vitamin D hormone and its nuclear receptor: Molecular actions and disease states","volume":"154","author":"Haussler","year":"1997","journal-title":"J Endocrinol"},{"key":"10.1016\/j.steroids.2023.109271_b0240","doi-asserted-by":"crossref","DOI":"10.1021\/acs.jmedchem.9b00208","article-title":"Vitamin D and is synthetic analogs","author":"Maestro","year":"2019","journal-title":"J Med Chem"},{"issue":"6","key":"10.1016\/j.steroids.2023.109271_b0245","doi-asserted-by":"crossref","first-page":"528","DOI":"10.2174\/156802612799436623","article-title":"Current status of vitamin D signaling and its therapeutic applications","volume":"12","author":"Carlberg","year":"2012","journal-title":"Curr Top Med Chem"},{"issue":"10","key":"10.1016\/j.steroids.2023.109271_b0250","first-page":"1455","article-title":"VDR-Alien: A novel, DNA-selective vitamin D3 receptor-corepressor partnership","volume":"14","author":"Polly","year":"2000","journal-title":"Faseb J"},{"issue":"5","key":"10.1016\/j.steroids.2023.109271_b0255","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1006\/jmbi.2000.4267","article-title":"Agonist-triggered modulation of the activated and silent state of the vitamin D3 receptor by interaction with co-repressors and co-activators","volume":"304","author":"Herdick","year":"2000","journal-title":"J. Mol. Biol."},{"issue":"2","key":"10.1016\/j.steroids.2023.109271_b0260","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.steroids.2012.10.019","article-title":"Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor","volume":"78","author":"Carlberg","year":"2013","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2023.109271_b0265","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.mce.2017.03.016","article-title":"Molecular endocrinology of vitamin D on the epigenome level","volume":"453","author":"Carlberg","year":"2017","journal-title":"Mol Cell Endocrinol"},{"issue":"5","key":"10.1016\/j.steroids.2023.109271_b0270","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.cell.2018.04.013","article-title":"Vitamin D switches BAF complexes to protect beta cells","volume":"173","author":"Wei","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.steroids.2023.109271_b0275","series-title":"Mechanisms of Gene Regulation","first-page":"159","article-title":"The epigenome, Mechanisms of Gene Regulation","author":"Carlberg","year":"2016"},{"key":"10.1016\/j.steroids.2023.109271_b0280","series-title":"Mechanisms of Gene Regulation","first-page":"17","article-title":"The impact of chromatin, Mechanisms of Gene Regulation","author":"Carlberg","year":"2016"},{"issue":"14","key":"10.1016\/j.steroids.2023.109271_b0285","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1016\/j.cell.2021.05.029","article-title":"Reading the chromatinized genome","volume":"184","author":"Michael","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.steroids.2023.109271_b0290","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature11247","article-title":"An integrated encyclopedia of DNA elements in the human genome","volume":"489","author":"ENCODE-Project-Consortium","year":"2012","journal-title":"Nature"},{"issue":"6413","key":"10.1016\/j.steroids.2023.109271_b0295","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/361657a0","article-title":"Two nuclear signalling pathways for vitamin D","volume":"361","author":"Carlberg","year":"1993","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.steroids.2023.109271_b0300","doi-asserted-by":"crossref","first-page":"e96105","DOI":"10.1371\/journal.pone.0096105","article-title":"Patterns of genome-wide VDR locations","volume":"9","author":"Tuoresm\u00e4ki","year":"2014","journal-title":"PLoS ONE"},{"issue":"21","key":"10.1016\/j.steroids.2023.109271_b0305","doi-asserted-by":"crossref","first-page":"9181","DOI":"10.1093\/nar\/gkr654","article-title":"Nuclear hormone 1\u03b1,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy","volume":"39","author":"Heikkinen","year":"2011","journal-title":"Nucleic Acids Res"},{"issue":"9","key":"10.1016\/j.steroids.2023.109271_b0310","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.bbagrm.2017.07.002","article-title":"Selective regulation of biological processes by vitamin D based on the spatio-temporal cistrome of its receptor","volume":"1860","author":"Neme","year":"2017","journal-title":"Biochim Biophys Acta"},{"issue":"7398","key":"10.1016\/j.steroids.2023.109271_b0315","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature11082","article-title":"Topological domains in mammalian genomes identified by analysis of chromatin interactions","volume":"485","author":"Dixon","year":"2012","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.steroids.2023.109271_b0320","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.bbagrm.2018.05.006","article-title":"The impact of the vitamin D-modulated epigenome on VDR target gene regulation","volume":"1861","author":"Nurminen","year":"2018","journal-title":"Biochim Biophys Acta"},{"issue":"9","key":"10.1016\/j.steroids.2023.109271_b0325","doi-asserted-by":"crossref","first-page":"4090","DOI":"10.1093\/nar\/gkv1519","article-title":"Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF","volume":"44","author":"Seuter","year":"2016","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"10.1016\/j.steroids.2023.109271_b0330","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.bbagrm.2017.02.005","article-title":"Epigenomic PU.1-VDR crosstalk modulates vitamin D signaling","volume":"1860","author":"Seuter","year":"2017","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"10.1016\/j.steroids.2023.109271_b0335","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bbagrm.2018.12.004","article-title":"Modulation of vitamin D signaling by the pioneer factor CEBPA","volume":"1862","author":"Nurminen","year":"2019","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.steroids.2023.109271_b0340","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3389\/fphys.2014.00335","article-title":"The physiology of vitamin D-far more than calcium and bone","volume":"5","author":"Carlberg","year":"2014","journal-title":"Front Physiol"},{"issue":"3","key":"10.1016\/j.steroids.2023.109271_b0345","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.bbagrm.2014.12.001","article-title":"The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D","volume":"1849","author":"Nurminen","year":"2015","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.steroids.2023.109271_b0350","first-page":"108487","article-title":"Rapid signalling responses via the G protein-coupled estrogen receptor","volume":"152","author":"Evans","year":"2019","journal-title":"GPER, in a hippocampal cell line, Steroids"},{"issue":"5","key":"10.1016\/j.steroids.2023.109271_b0355","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1210\/er.2018-00087","article-title":"Estrogen receptors: New directions in the new millennium","volume":"39","author":"Hewitt","year":"2018","journal-title":"Endocr Rev"},{"key":"10.1016\/j.steroids.2023.109271_b0360","doi-asserted-by":"crossref","first-page":"105496","DOI":"10.1016\/j.jsbmb.2019.105496","article-title":"Vascular mechanisms of testosterone: The non-genomic point of view","volume":"196","author":"Lorigo","year":"2020","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.steroids.2023.109271_b0365","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/bs.vh.2018.12.001","article-title":"Non-genomic effects of aldosterone","volume":"109","author":"Mihailidou","year":"2019","journal-title":"Vitam Horm"},{"key":"10.1016\/j.steroids.2023.109271_b0370","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/bs.ircmb.2019.03.004","article-title":"Nongenomic glucocorticoid effects and their mechanisms of action in vertebrates","volume":"346","author":"Johnstone","year":"2019","journal-title":"Int Rev Cell Mol Biol"},{"key":"10.1016\/j.steroids.2023.109271_b0375","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.steroids.2018.02.006","article-title":"Role of the ERp57 protein (1,25D3-MARRS receptor) in murine mammary gland growth and development","volume":"135","author":"Wilkin","year":"2018","journal-title":"Steroids"},{"issue":"3","key":"10.1016\/j.steroids.2023.109271_b0380","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/jcb.24986","article-title":"The 1,25D3-MARRS receptor\/PDIA3\/ERp57 and lifespan","volume":"116","author":"Nemere","year":"2015","journal-title":"J Cell Biochem"},{"issue":"10","key":"10.1016\/j.steroids.2023.109271_b0385","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.steroids.2012.04.002","article-title":"Role of the 1,25D3-MARRS receptor in the 1,25(OH)2D3-stimulated uptake of calcium and phosphate in intestinal cells","volume":"77","author":"Nemere","year":"2012","journal-title":"Steroids"},{"issue":"41","key":"10.1016\/j.steroids.2023.109271_b0390","doi-asserted-by":"crossref","first-page":"31859","DOI":"10.1074\/jbc.M110.116954","article-title":"Intestinal cell calcium uptake and the targeted knockout of the 1,25D3-MARRS (membrane-associated, rapid response steroid-binding) receptor\/PDIA3\/Erp57","volume":"285","author":"Nemere","year":"2010","journal-title":"J Biol Chem"},{"key":"10.1016\/j.steroids.2023.109271_b0395","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jsbmb.2014.11.002","article-title":"Membrane-mediated actions of 1,25-dihydroxy vitamin D3: A review of the roles of phospholipase A2 activating protein and Ca2+\/calmodulin-dependent protein kinase II","volume":"147","author":"Doroudi","year":"2015","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"1\u20132","key":"10.1016\/j.steroids.2023.109271_b0400","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jsbmb.2012.03.001","article-title":"Phospholipase A2 activating protein is required for 1\u03b1,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3","volume":"132","author":"Doroudi","year":"2012","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"2","key":"10.1016\/j.steroids.2023.109271_b0405","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/exd.14068","article-title":"The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond","volume":"29","author":"Egger","year":"2020","journal-title":"Exp Dermatol"},{"issue":"7","key":"10.1016\/j.steroids.2023.109271_b0410","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1210\/me.2012-1277","article-title":"Chaperone properties of pdia3 participate in rapid membrane actions of 1\u03b1,25-dihydroxyvitamin D3","volume":"27","author":"Chen","year":"2013","journal-title":"Mol Endocrinol"},{"issue":"12","key":"10.1016\/j.steroids.2023.109271_b0415","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1016\/j.cellsig.2013.07.020","article-title":"Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1\u03b1,25(OH)2D3","volume":"25","author":"Chen","year":"2013","journal-title":"Cell Signal"},{"issue":"4","key":"10.1016\/j.steroids.2023.109271_b0420","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.beem.2011.05.010","article-title":"Vitamin D receptor (VDR)-mediated actions of 1\u03b1,25(OH)\u2082vitamin D3: Genomic and non-genomic mechanisms","volume":"25","author":"Haussler","year":"2011","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.steroids.2023.109271_b0425","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.steroids.2006.11.004","article-title":"Phosphate uptake in chick kidney cells: Effects of 1,25(OH)2D3 and 24,25(OH)2D3","volume":"72","author":"Khanal","year":"2007","journal-title":"Steroids"},{"key":"10.1016\/j.steroids.2023.109271_b0430","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3389\/fendo.2018.00250","article-title":"Vitamin D genomics: From in vitro to in vivo","volume":"9","author":"Carlberg","year":"2018","journal-title":"Front Endocrinol"},{"issue":"10 Suppl 2","key":"10.1016\/j.steroids.2023.109271_b0435","doi-asserted-by":"crossref","first-page":"S125","DOI":"10.1111\/j.1753-4887.2008.00096.x","article-title":"Regulation of vitamin D homeostasis: Implications for the immune system","volume":"66","author":"van Etten","year":"2008","journal-title":"Nutrition reviews"}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X23000995?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X23000995?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T10:10:24Z","timestamp":1758535824000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X23000995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":87,"alternative-id":["S0039128X23000995"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2023.109271","relation":{},"ISSN":["0039-128X"],"issn-type":[{"value":"0039-128X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genomic signaling of vitamin D","name":"articletitle","label":"Article Title"},{"value":"Steroids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.steroids.2023.109271","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"109271"}}