{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:54:20Z","timestamp":1791060860326,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100022807","name":"Division of Research, Innovation, Synergies and Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["RS-2024-00406555"],"award-info":[{"award-number":["RS-2024-00406555"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2026-RISE-10-005"],"award-info":[{"award-number":["2026-RISE-10-005"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Steroids"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.steroids.2026.109854","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:43:09Z","timestamp":1789141389000},"page":"109854","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Inhibition of soluble epoxide hydrolase by steroidal metabolites from the starfish Patiria pectinifera: Integrated enzyme kinetic and computational studies"],"prefix":"10.1016","volume":"235-236","author":[{"given":"Nguyen Viet","family":"Phong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le Ba","family":"Vinh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoang Le Tuan","family":"Anh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Don","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seo Young","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0005","doi-asserted-by":"crossref","DOI":"10.1186\/s43556-025-00395-z","article-title":"Inflammatory bowel diseases: pathological mechanisms and therapeutic perspectives","volume":"7","author":"Yang","year":"2026","journal-title":"Mol. Biomed."},{"key":"10.1016\/j.steroids.2026.109854_bb0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1625087","article-title":"Lipid metabolic dysregulation-induced neuroinflammation in the pathophysiology of major depressive disorder","volume":"16","author":"Ge","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.steroids.2026.109854_bb0015","series-title":"Druggable Lipid Signaling Pathways","first-page":"71","article-title":"Epoxy fatty acids are promising targets for treatment of pain, cardiovascular disease and other indications characterized by mitochondrial dysfunction, endoplasmic stress and inflammation","author":"McReynolds","year":"2020"},{"issue":"4","key":"10.1016\/j.steroids.2026.109854_bb0020","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1161\/HYPERTENSIONAHA.121.17659","article-title":"GSK2256294 decreases sEH (soluble epoxide hydrolase) activity in plasma, muscle, and adipose and reduces F2-isoprostanes but does not alter insulin sensitivity in humans","volume":"78","author":"Luther","year":"2021","journal-title":"Hypertension"},{"key":"10.1016\/j.steroids.2026.109854_bb0025","article-title":"Insights into the potential role of sEH inhibition in the prevention and progression of neurological disorders","volume":"19","author":"Gavisiddaiah","year":"2025","journal-title":"Endocr. Metab. Sci."},{"issue":"2","key":"10.1016\/j.steroids.2026.109854_bb0030","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1021\/acsptsci.4c00629","article-title":"Novel soluble epoxide hydrolase inhibitor: toward regulatory preclinical studies","volume":"8","author":"Jarne-Ferrer","year":"2025","journal-title":"ACS Pharmacol. Transl. Sci."},{"issue":"11","key":"10.1016\/j.steroids.2026.109854_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2025.110737","article-title":"Putative receptors and signaling pathways responsible for the biological actions of epoxyeicosatrienoic acids","volume":"301","author":"Edin","year":"2025","journal-title":"J. Biol. Chem."},{"issue":"23","key":"10.1016\/j.steroids.2026.109854_bb0040","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1080\/17568919.2025.2580912","article-title":"Developments in small-molecule soluble epoxide hydrolase inhibitors: synthetic advances and therapeutic applications","volume":"17","author":"Wang","year":"2025","journal-title":"Future Med. Chem."},{"key":"10.1016\/j.steroids.2026.109854_bb0045","article-title":"Discovery of marine-derived ent-atisane diterpenoid lead compounds targeting sEH for Alzheimer's disease therapy","author":"Yang","year":"2025","journal-title":"Chin. Chem. Lett."},{"issue":"8","key":"10.1016\/j.steroids.2026.109854_bb0050","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3390\/md22080373","article-title":"Inhibition of soluble epoxide hydrolase by cembranoid diterpenes from soft coral Sinularia maxima: enzyme kinetics, molecular docking, and molecular dynamics","volume":"22","author":"Phong","year":"2024","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.steroids.2026.109854_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103912","article-title":"Current progress on identification of virus pathogens and the antiviral effectors in echinoderms","volume":"116","author":"Guo","year":"2021","journal-title":"Dev. Comp. Immunol."},{"issue":"5","key":"10.1016\/j.steroids.2026.109854_bb0060","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1002\/cbdv.200900344","article-title":"Chemical constituents and bioactivities of starfish","volume":"8","author":"Dong","year":"2011","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.steroids.2026.109854_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2022.117144","article-title":"Neuritogenic steroid glycosides from crown-of-thorns starfish: possible involvement of p38 mitogen-activated protein kinase and attenuation of cognitive impairment in senescence-accelerated mice (SAMP8) by peripheral administration","volume":"78","author":"Sasayama","year":"2023","journal-title":"Bioorg. Med. Chem."},{"issue":"21","key":"10.1016\/j.steroids.2026.109854_bb0070","doi-asserted-by":"crossref","first-page":"5545","DOI":"10.1080\/14786419.2021.2021200","article-title":"First report of steroid derivatives isolated from starfish Acanthaster planci with anti-bacterial, anti-cancer and anti-diabetic activities","volume":"36","author":"Abd El Hafez","year":"2022","journal-title":"Nat. Prod. Res."},{"issue":"17","key":"10.1016\/j.steroids.2026.109854_bb0075","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.3390\/molecules24173154","article-title":"Effects of polar steroids from the starfish Patiria (=Asterina) pectinifera in combination with X-ray radiation on colony formation and apoptosis induction of human colorectal carcinoma cells","volume":"24","author":"Malyarenko","year":"2019","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.steroids.2026.109854_bb0080","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3390\/md18050260","article-title":"New conjugates of polyhydroxysteroids with long-chain fatty acids from the deep-water far eastern starfish Ceramaster patagonicus and their anticancer activity","volume":"18","author":"Malyarenko","year":"2020","journal-title":"Mar. Drugs"},{"issue":"11","key":"10.1016\/j.steroids.2026.109854_bb0085","doi-asserted-by":"crossref","first-page":"693","DOI":"10.3390\/md20110693","article-title":"Anti-inflammatory effects of compounds from echinoderms","volume":"20","author":"Ghelani","year":"2022","journal-title":"Mar. Drugs"},{"issue":"11","key":"10.1016\/j.steroids.2026.109854_bb0090","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3390\/md17110617","article-title":"Bright spots in the darkness of cancer: a review of starfishes-derived compounds and their anti-tumor action","volume":"17","author":"Lazzara","year":"2019","journal-title":"Mar. Drugs"},{"issue":"11","key":"10.1016\/j.steroids.2026.109854_bb0095","doi-asserted-by":"crossref","first-page":"420","DOI":"10.3390\/md16110420","article-title":"In vitro anticancer and proapoptotic activities of steroidal glycosides from the starfish Anthenea aspera","volume":"16","author":"Malyarenko","year":"2018","journal-title":"Mar. Drugs"},{"issue":"19","key":"10.1016\/j.steroids.2026.109854_bb0100","doi-asserted-by":"crossref","first-page":"5643","DOI":"10.1080\/14786419.2024.2350639","article-title":"Polyhydroxy steroids isolated from starfish (Asterina pectinifera) and their embryotoxicity","volume":"39","author":"Zhang","year":"2025","journal-title":"Nat. Prod. Res."},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0105","doi-asserted-by":"crossref","first-page":"37","DOI":"10.5487\/TR.2010.26.1.037","article-title":"Methanolic extract of Asterina pectinifera inhibits LPS-induced inflammatory mediators in murine macrophage","volume":"26","author":"Jo","year":"2010","journal-title":"Toxicol. Res."},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0110","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s10068-016-0104-9","article-title":"Radical scavenging activities of Asterina pectinifera fermented with Cordyceps militaris mycelia","volume":"25","author":"Kim","year":"2016","journal-title":"Food Sci. Biotechnol."},{"key":"10.1016\/j.steroids.2026.109854_bb0115","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.dci.2018.05.002","article-title":"Identification of a novel antimicrobial peptide from the sea star Patiria pectinifera","volume":"86","author":"Kim","year":"2018","journal-title":"Dev. Comp. Immunol."},{"issue":"9","key":"10.1016\/j.steroids.2026.109854_bb0120","doi-asserted-by":"crossref","first-page":"470","DOI":"10.3390\/md21090470","article-title":"Carotenoids from starfish Patiria pectinifera: therapeutic activity in models of inflammatory diseases","volume":"21","author":"Popov","year":"2023","journal-title":"Mar. Drugs"},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0125","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1038\/s41598-017-02171-8","article-title":"Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae","volume":"7","author":"Saito","year":"2017","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0130","doi-asserted-by":"crossref","DOI":"10.1080\/14756366.2024.2447719","article-title":"Indirubin-3\u2032-oxime as a dual-action agent: mitigating heat-induced male infertility in Drosophila melanogaster and inhibiting soluble epoxide hydrolase","volume":"40","author":"Phong","year":"2025","journal-title":"J. Enzym. Inhib. Med. Chem."},{"issue":"2","key":"10.1016\/j.steroids.2026.109854_bb0135","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s10822-025-00673-6","article-title":"Bioactive constituents isolated from the leaves of Phyllostachys bambusoides with potent soluble epoxide hydrolase inhibitory activity: enzyme kinetics, molecular docking, and molecular dynamics simulations","volume":"39","author":"Li","year":"2025","journal-title":"J. Comput. Aided Mol. Des."},{"issue":"9","key":"10.1016\/j.steroids.2026.109854_bb0140","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1021\/acs.jchemed.9b00396","article-title":"Michaelis\u2013Menten graphs, Lineweaver\u2013Burk plots, and reaction schemes: investigating introductory biochemistry students' conceptions of representations in enzyme kinetics","volume":"96","author":"Rodriguez","year":"2019","journal-title":"J. Chem. Educ."},{"issue":"8","key":"10.1016\/j.steroids.2026.109854_bb0145","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1021\/acs.jcim.1c00203","article-title":"AutoDock Vina 1.2.0: new docking methods, expanded force field, and python bindings","volume":"61","author":"Eberhardt","year":"2021","journal-title":"J. Chem. Inf. Model."},{"issue":"5","key":"10.1016\/j.steroids.2026.109854_bb0150","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1038\/nprot.2016.051","article-title":"Computational protein\u2013ligand docking and virtual drug screening with the AutoDock suite","volume":"11","author":"Forli","year":"2016","journal-title":"Nat. Protoc."},{"issue":"9","key":"10.1016\/j.steroids.2026.109854_bb0155","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/j.drudis.2015.04.005","article-title":"Successful generation of structural information for fragment-based drug discovery","volume":"20","author":"\u00d6ster","year":"2015","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.steroids.2026.109854_bb0160","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.softx.2015.06.001","article-title":"GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers","volume":"1-2","author":"Abraham","year":"2015","journal-title":"SoftwareX"},{"key":"10.1016\/j.steroids.2026.109854_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.147487","article-title":"Potent \u03b2-glucuronidase inhibition by brown algae Ecklonia cava secondary metabolites: structural characterization, enzyme kinetics, and computational simulations","volume":"327","author":"Phong","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0170","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/nmeth.4067","article-title":"CHARMM36m: an improved force field for folded and intrinsically disordered proteins","volume":"14","author":"Huang","year":"2017","journal-title":"Nat. Methods"},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0175","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1021\/acs.jctc.5b00935","article-title":"CHARMM-GUI input generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM\/OpenMM simulations using the CHARMM36 additive force field","volume":"12","author":"Lee","year":"2016","journal-title":"J. Chem. Theory Comput."},{"issue":"2","key":"10.1016\/j.steroids.2026.109854_bb0180","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3390\/md9020162","article-title":"New cytotoxic oxygenated sterols from the marine bryozoan Cryptosula pallasiana","volume":"9","author":"Tian","year":"2011","journal-title":"Mar. Drugs"},{"issue":"7","key":"10.1016\/j.steroids.2026.109854_bb0185","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/S0022-2275(20)39137-9","article-title":"Analysis of unsaturated C27 sterols by nuclear magnetic resonance spectroscopy","volume":"37","author":"Wilson","year":"1996","journal-title":"J. Lipid Res."},{"issue":"20","key":"10.1016\/j.steroids.2026.109854_bb0190","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1080\/14786419.2012.761621","article-title":"Three new steroid glycosides from the starfish Asterina pectinifera","volume":"27","author":"Li","year":"2013","journal-title":"Nat. Prod. Res."},{"issue":"36","key":"10.1016\/j.steroids.2026.109854_bb0195","doi-asserted-by":"crossref","first-page":"3893","DOI":"10.1016\/S0040-4039(00)94305-3","article-title":"Asterosaponin P1 from the starfish Patiria pectinifera","volume":"24","author":"Kicha","year":"1983","journal-title":"Tetrahedron Lett."},{"issue":"5","key":"10.1016\/j.steroids.2026.109854_bb0200","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1021\/np50041a006","article-title":"Starfish saponins, part 21. Steroidal glycosides from the starfish Oreaster reticulatus","volume":"48","author":"de Correa","year":"1985","journal-title":"J. Nat. Prod."},{"issue":"2","key":"10.1016\/j.steroids.2026.109854_bb0205","doi-asserted-by":"crossref","DOI":"10.3390\/toxics11020137","article-title":"Embryotoxicity and teratogenicity of steroidal saponin isolated from Ophiopholis mirabilis","volume":"11","author":"Xu","year":"2023","journal-title":"Toxics"},{"issue":"4","key":"10.1016\/j.steroids.2026.109854_bb0210","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1021\/acs.jcim.5b00592","article-title":"Discovery of potent soluble epoxide hydrolase (sEH) inhibitors by pharmacophore-based virtual screening","volume":"56","author":"Waltenberger","year":"2016","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.steroids.2026.109854_bb0215","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1146\/annurev-pharmtox-010611-134525","article-title":"Drugs for allosteric sites on receptors","volume":"54","author":"Wenthur","year":"2014","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"18","key":"10.1016\/j.steroids.2026.109854_bb0220","doi-asserted-by":"crossref","first-page":"8443","DOI":"10.1021\/acs.jmedchem.9b00445","article-title":"Discovery of the first in vivo active inhibitors of the soluble epoxide hydrolase phosphatase domain","volume":"62","author":"Kramer","year":"2019","journal-title":"J. Med. Chem."},{"issue":"2","key":"10.1016\/j.steroids.2026.109854_bb0225","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.gene.2013.05.008","article-title":"Soluble epoxide hydrolase: Gene structure, expression and deletion","volume":"526","author":"Harris","year":"2013","journal-title":"Gene"},{"key":"10.1016\/j.steroids.2026.109854_bb0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.compbiolchem.2018.02.019","article-title":"Discovery of novel drug candidates for inhibition of soluble epoxide hydrolase of arachidonic acid cascade pathway implicated in atherosclerosis","volume":"74","author":"Gurung","year":"2018","journal-title":"Comput. Biol. Chem."},{"issue":"24","key":"10.1016\/j.steroids.2026.109854_bb0235","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252413496","article-title":"Intradomain allosteric regulation of soluble epoxide hydrolase by its substrates","volume":"25","author":"Matsumura","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.steroids.2026.109854_bb0240","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.ijbiomac.2019.04.055","article-title":"Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: kinetics and interaction mechanism merged with simulations","volume":"133","author":"Liu","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"issue":"19","key":"10.1016\/j.steroids.2026.109854_bb0245","doi-asserted-by":"crossref","first-page":"10637","DOI":"10.1073\/pnas.96.19.10637","article-title":"Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase","volume":"96","author":"Argiriadi","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"10.1016\/j.steroids.2026.109854_bb0250","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1093\/bioinformatics\/btp163","article-title":"Biopython: freely available Python tools for computational molecular biology and bioinformatics","volume":"25","author":"Cock","year":"2009","journal-title":"Bioinformatics"},{"issue":"2","key":"10.1016\/j.steroids.2026.109854_bb0255","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s10822-025-00672-7","article-title":"Bioactive metabolites from Paeonia lactiflora protect against heat-induced male infertility in Drosophila melanogaster by modulating vasa: integrating in vivo and computational analyses","volume":"39","author":"Phong","year":"2025","journal-title":"J. Comput. Aided Mol. Des."},{"issue":"20","key":"10.1016\/j.steroids.2026.109854_bb0260","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1016\/j.bmc.2016.08.010","article-title":"Challenges of docking in large, flexible and promiscuous binding sites","volume":"24","author":"Kotev","year":"2016","journal-title":"Bioorg. Med. Chem."},{"issue":"1","key":"10.1016\/j.steroids.2026.109854_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.patter.2021.100408","article-title":"Prediction of allosteric sites and signaling: insights from benchmarking datasets","volume":"3","author":"Wu","year":"2022","journal-title":"Patterns"}],"container-title":["Steroids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X26001169?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039128X26001169?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:16:49Z","timestamp":1791058609000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039128X26001169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":53,"alternative-id":["S0039128X26001169"],"URL":"https:\/\/doi.org\/10.1016\/j.steroids.2026.109854","relation":{},"ISSN":["0039-128X"],"issn-type":[{"value":"0039-128X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of soluble epoxide hydrolase by steroidal metabolites from the starfish Patiria pectinifera: Integrated enzyme kinetic and computational studies","name":"articletitle","label":"Article Title"},{"value":"Steroids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.steroids.2026.109854","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109854"}}