{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:45:17Z","timestamp":1791276317546,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T00:00:00Z","timestamp":1122854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2005,8]]},"DOI":"10.1016\/j.surg.2005.04.009","type":"journal-article","created":{"date-parts":[[2005,9,9]],"date-time":"2005-09-09T15:51:53Z","timestamp":1126281113000},"page":"313-320","source":"Crossref","is-referenced-by-count":35,"title":["Repair after cholestatic liver injury correlates with neutrophil infiltration and matrix metalloproteinase 8 activity"],"prefix":"10.1016","volume":"138","author":[{"given":"Mark W.","family":"Harty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah M.","family":"Huddleston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine F.","family":"Papa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tauquir","family":"Puthawala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron P.","family":"Tracy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant A.","family":"Ramm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Gehring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen H.","family":"Gregory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Thomas F.","family":"Tracy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2005.04.009_bib1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0002-9440(10)65595-2","article-title":"Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia","volume":"153","author":"Ramm","year":"1998","journal-title":"Am J Pathol"},{"key":"10.1016\/j.surg.2005.04.009_bib2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1034\/j.1600-0676.2000.020005387.x","article-title":"Morphology of liver repair following cholestatic liver injury: resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts","volume":"20","author":"Ramm","year":"2000","journal-title":"Liver"},{"key":"10.1016\/j.surg.2005.04.009_bib3","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0022-3468(96)90333-4","article-title":"The inflammatory response in pediatric biliary disease: macrophage phenotype and distribution","volume":"31","author":"Tracy","year":"1996","journal-title":"J Pediatr Surg"},{"issue":"Suppl 1","key":"10.1016\/j.surg.2005.04.009_bib4","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1016\/S0168-8278(02)00429-4","article-title":"Liver fibrosis\u2014from bench to bedside","volume":"38","author":"Friedman","year":"2003","journal-title":"J Hepatol"},{"key":"10.1016\/j.surg.2005.04.009_bib5","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0022-3468(03)00499-8","article-title":"The Kasai portoenterostomy for biliary atresia: A review of a 27-year experience with 81 patients","volume":"38","author":"Wildhaber","year":"2003","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.surg.2005.04.009_bib6","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1177\/000313480206800917","article-title":"Bile decompression in children with histopathological evidence of pre-existing liver cirrhosis","volume":"68","author":"Jackson","year":"2002","journal-title":"Am Surg"},{"key":"10.1016\/j.surg.2005.04.009_bib7","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1056\/NEJM200102083440604","article-title":"Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct","volume":"344","author":"Hammel","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.surg.2005.04.009_bib8","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/gut.46.4.443","article-title":"Is liver fibrosis reversible?","volume":"46","author":"Benyon","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.surg.2005.04.009_bib9","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1056\/NEJM200102083440610","article-title":"Is liver fibrosis reversible?","volume":"344","author":"Bonis","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.surg.2005.04.009_bib10","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1172\/JCI1018","article-title":"Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors","volume":"102","author":"Iredale","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.surg.2005.04.009_bib11","first-page":"532","article-title":"Growth-related gene expression in early cholestatic liver injury","volume":"114","author":"Tracy","year":"1993","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2005.04.009_bib12","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/0016-5085(90)91030-A","article-title":"Origin, pattern, and mechanism of bile duct proliferation following biliary obstruction in the rat","volume":"99","author":"Slott","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.surg.2005.04.009_bib13","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1053\/jpsu.2001.20059","article-title":"Macrophage phenotype during cholestatic injury and repair: the persistent inflammatory response","volume":"36","author":"Roggin","year":"2001","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.surg.2005.04.009_bib14","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S0016-5085(00)70369-6","article-title":"Bile duct ligation in rats induces biliary expression of cytokine-induced neutrophil chemoattractant","volume":"118","author":"Saito","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.surg.2005.04.009_bib15","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S1386-6346(02)00247-4","article-title":"Infiltrating neutrophils in bile duct-ligated livers do not promote hepatic fibrosis","volume":"25","author":"Saito","year":"2003","journal-title":"Hepatol Res"},{"key":"10.1016\/j.surg.2005.04.009_bib16","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/hep.1840080207","article-title":"Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood in patients with cirrhosis","volume":"8","author":"Lumsden","year":"1988","journal-title":"Hepatology"},{"key":"10.1016\/j.surg.2005.04.009_bib17","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1055\/s-2007-1007337","article-title":"Kupffer cells: their activation and role in animal models of liver injury and human liver disease","volume":"13","author":"Winwood","year":"1993","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.surg.2005.04.009_bib18","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jss.2004.03.020","article-title":"Biliary intervention augments chemotactic reaction and aggravates cholestatic liver injury in rats","volume":"120","author":"Chuang","year":"2004","journal-title":"J Surg Res"},{"key":"10.1016\/j.surg.2005.04.009_bib19","doi-asserted-by":"crossref","first-page":"G245","DOI":"10.1152\/ajpgi.2000.279.2.G245","article-title":"Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis","volume":"279","author":"Arthur","year":"2000","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.surg.2005.04.009_bib20","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/00005176-199807000-00013","article-title":"Mechanisms of hepatic fibrosis","volume":"27","author":"Benyon","year":"1998","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.surg.2005.04.009_bib21","doi-asserted-by":"crossref","first-page":"7791","DOI":"10.4049\/jimmunol.172.12.7791","article-title":"Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase","volume":"172","author":"Owen","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.surg.2005.04.009_bib22","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/S0002-9440(10)64312-X","article-title":"Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells","volume":"162","author":"Schaefer","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.surg.2005.04.009_bib23","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1006\/bbrc.1999.1910","article-title":"Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis","volume":"267","author":"Hironaka","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.surg.2005.04.009_bib24","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/S0024-3205(02)02342-1","article-title":"Gadolinium chloride reverses dimethylnitrosamine (DMN)-induced rat liver fibrosis with increased matrix metalloproteinases (MMPs) of Kupffer cells","volume":"72","author":"Sakaida","year":"2003","journal-title":"Life Sci"},{"key":"10.1016\/j.surg.2005.04.009_bib25","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00000441-199109000-00010","article-title":"Inflammatory phagocytes and connective tissue degrading metalloproteinases","volume":"302","author":"Mainardi","year":"1991","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.surg.2005.04.009_bib26","doi-asserted-by":"crossref","first-page":"31504","DOI":"10.1074\/jbc.272.50.31504","article-title":"Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline","volume":"272","author":"Hanemaaijer","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.surg.2005.04.009_bib27","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1161\/hc4101.097419","article-title":"Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling","volume":"104","author":"Herman","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.surg.2005.04.009_bib28","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1146\/annurev.cellbio.17.1.463","article-title":"How matrix metalloproteinases regulate cell behavior","volume":"17","author":"Sternlicht","year":"2001","journal-title":"Annu Rev Cell Dev Biol"},{"key":"10.1016\/j.surg.2005.04.009_bib29","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1172\/JCI200421087","article-title":"MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs","volume":"113","author":"Sitia","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.surg.2005.04.009_bib30","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1006\/jsre.2000.5879","article-title":"Kupffer cell inactivation delays repair in a rat model of reversible biliary obstruction","volume":"90","author":"Roggin","year":"2000","journal-title":"J Surg Res"},{"key":"10.1016\/j.surg.2005.04.009_bib31","first-page":"503","article-title":"Differential expression of matrix metalloproteinase during liver repair: evidence of hepatic macrophage regulation","volume":"54","author":"Roggin","year":"2001","journal-title":"Surg Forum"},{"key":"10.1016\/j.surg.2005.04.009_bib32","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0022-4804(90)90214-M","article-title":"A model of reversible obstructive jaundice in the rat","volume":"48","author":"Posner","year":"1990","journal-title":"J Surg Res"},{"key":"10.1016\/j.surg.2005.04.009_bib33","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1354\/vp.40-3-227","article-title":"In situ zymography: a molecular pathology technique to localize endogenous protease activity in tissue sections","volume":"40","author":"Yan","year":"2003","journal-title":"Vet Pathol"},{"key":"10.1016\/j.surg.2005.04.009_bib34","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/toxsci\/65.2.166","article-title":"Mechanisms of hepatotoxicity","volume":"65","author":"Jaeschke","year":"2002","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.surg.2005.04.009_bib35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1432-1033.1990.tb19222.x","article-title":"Biologically active products of stimulated liver macrophages (Kupffer cells)","volume":"192","author":"Decker","year":"1990","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.surg.2005.04.009_bib36","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1159\/000163663","article-title":"Regulation of nitric oxide production by stimulated rat Kupffer cells","volume":"59","author":"Gaillard","year":"1991","journal-title":"Pathobiology"},{"key":"10.1016\/j.surg.2005.04.009_bib37","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.bbrc.2004.07.147","article-title":"The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice","volume":"322","author":"Ishizaki-Koizumi","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.surg.2005.04.009_bib38","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/S0002-9440(10)61117-0","article-title":"The role of hepatic stellate cells and transforming growth factor-beta(1) in cystic fibrosis liver disease","volume":"160","author":"Lewindon","year":"2002","journal-title":"Am J Pathol"},{"issue":"Suppl 1","key":"10.1016\/j.surg.2005.04.009_bib39","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1186\/1476-5926-2-S1-S5","article-title":"Signals for hepatic fibrogenesis in pediatric cholestatic liver disease: review and hypothesis","volume":"3","author":"Ramm","year":"2004","journal-title":"Comp Hepatol"},{"issue":"Suppl 3","key":"10.1016\/j.surg.2005.04.009_bib40","first-page":"S50","article-title":"Matrix regulation and MMP activity during liver repair is macrophage dependent","volume":"197","author":"Fukudome","year":"2003","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.surg.2005.04.009_bib41","series-title":"Inflammation: Basic principles and clinical correlates","first-page":"703","article-title":"Degranulation","author":"Berton","year":"1999"},{"key":"10.1016\/j.surg.2005.04.009_bib42","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1054\/mehy.2001.1313","article-title":"Neutrophil degranulation: coactivation of chemokine receptor(s) is required for extracellular nucleotide-induced neutrophil degranulation","volume":"57","author":"Kannan","year":"2001","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.surg.2005.04.009_bib43","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1056\/NEJM198902093200606","article-title":"Tissue destruction by neutrophils","volume":"320","author":"Weiss","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1016\/j.surg.2005.04.009_bib44","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/jlb.61.4.375","article-title":"Apoptosis in resolution of inflammation","volume":"61","author":"Savill","year":"1997","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.surg.2005.04.009_bib45","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1600-0609.2004.00263.x","article-title":"Macrophages in spleen and liver direct the migration pattern of rat neutrophils during inflammation","volume":"73","author":"Knudsen","year":"2004","journal-title":"Eur J Haematol"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606005001741?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606005001741?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T15:20:09Z","timestamp":1706541609000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606005001741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["S0039606005001741"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2005.04.009","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}