{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T03:00:43Z","timestamp":1779159643110,"version":"3.51.4"},"reference-count":16,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["surgjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.surg.2016.09.043","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T01:01:47Z","timestamp":1484614907000},"page":"1266-1272","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Hepatic Prominin-1 expression is associated with biliary fibrosis"],"prefix":"10.1016","volume":"161","author":[{"given":"Marie V.","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica A.","family":"Zagory","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William H.","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Fenlon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menghan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiabo","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Lua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmala","family":"Mavila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinji","family":"Asahina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasper S.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2016.09.043_bib1","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1097\/SLA.0b013e3182300950","article-title":"The anatomic pattern of biliary atresia identified at time of Kasai hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of transplant-free survival","volume":"254","author":"Superina","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2016.09.043_bib2","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1097\/MOP.0000000000000214","article-title":"Recent advances in the pathogenesis and management of biliary atresia","volume":"27","author":"Zagory","year":"2015","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.surg.2016.09.043_bib3","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1038\/nature07589","article-title":"Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation","volume":"457","author":"Zhu","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.surg.2016.09.043_bib4","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1016\/j.febslet.2010.01.050","article-title":"The intriguing links between prominin-1 (CD133), cholesterol-based membrane microdomains, remodeling of apical plasma membrane protrusions, extracellular membrane particles, and (neuro)epithelial cell differentiation","volume":"584","author":"Corbeil","year":"2010","journal-title":"FEBS Lett"},{"key":"10.1016\/j.surg.2016.09.043_bib5","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1242\/jcs.02439","article-title":"Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells","volume":"118","author":"Marzesco","year":"2005","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.surg.2016.09.043_bib6","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1007\/s00109-008-0357-8","article-title":"The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells","volume":"86","author":"Bidlingmaier","year":"2008","journal-title":"J\u00a0Mol Med (Berl)"},{"key":"10.1016\/j.surg.2016.09.043_bib7","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1016\/j.cell.2016.07.045","article-title":"Multi-organ mapping of cancer risk","volume":"166","author":"Zhu","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.surg.2016.09.043_bib8","article-title":"Functional human and murine tissue-engineered liver is generated from adult stem\/progenitor cells","author":"Mavila","year":"2016","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.surg.2016.09.043_bib9","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1002\/hep.27203","article-title":"Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia","volume":"60","author":"Mavila","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.surg.2016.09.043_bib10","doi-asserted-by":"publisher","first-page":"E3297","DOI":"10.1073\/pnas.1400062111","article-title":"Origin of myofibroblasts in the fibrotic liver in mice","volume":"111","author":"Iwaisako","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.surg.2016.09.043_bib11","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1016\/j.jhep.2016.01.010","article-title":"Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers","volume":"64","author":"Lua","year":"2016","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.surg.2016.09.043_bib12","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/j.jhep.2013.12.017","article-title":"Fibroblast growth factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent \u03b2-catenin activation","volume":"60","author":"Utley","year":"2014","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.surg.2016.09.043_bib13","doi-asserted-by":"publisher","first-page":"e50401","DOI":"10.1371\/journal.pone.0050401","article-title":"Fibroblast growth factor receptor-mediated activation of AKT-beta-catenin-CBP pathway regulates survival and proliferation of murine hepatoblasts and hepatic tumor initiating stem cells","volume":"7","author":"Mavila","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.surg.2016.09.043_bib14","doi-asserted-by":"publisher","first-page":"2419","DOI":"10.1634\/stemcells.2007-0176","article-title":"A\u00a0CD133-expressing murine liver oval cell population with bilineage potential","volume":"25","author":"Rountree","year":"2007","journal-title":"Stem Cells"},{"key":"10.1016\/j.surg.2016.09.043_bib15","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1002\/hep.23748","article-title":"Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion","volume":"52","author":"Ding","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.surg.2016.09.043_bib16","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jss.2008.05.023","article-title":"Integrin alphavbeta6 and mediators of extracellular matrix deposition are up-regulated in experimental biliary atresia","volume":"154","author":"Nadler","year":"2009","journal-title":"J\u00a0Surg Res"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606016306456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606016306456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T02:28:06Z","timestamp":1536114486000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606016306456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0039606016306456"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2016.09.043","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hepatic Prominin-1 expression is associated with biliary fibrosis","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2016.09.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}