{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:55:28Z","timestamp":1782212128843,"version":"3.54.5"},"reference-count":19,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["surgjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.surg.2017.04.027","type":"journal-article","created":{"date-parts":[[2017,11,3]],"date-time":"2017-11-03T18:32:44Z","timestamp":1509733964000},"page":"31-34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Familial isolated primary hyperparathyroidism associated with germline GCM2 mutations is more aggressive and has a lesser rate of biochemical cure"],"prefix":"10.1016","volume":"163","author":[{"given":"Mustapha","family":"El Lakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Nockel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunita","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Welch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F.","family":"Simonds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Marx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naris","family":"Nilubol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaval","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lily","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxanne","family":"Merkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Electron","family":"Kebebew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2017.04.027_bib0010","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1210\/jc.2012-4022","article-title":"Incidence and prevalence of primary hyperparathyroidism in a racially mixed population","volume":"98","author":"Yeh","year":"2013","journal-title":"J Clin Endocrinol Metabol"},{"issue":"suppl 2","key":"10.1016\/j.surg.2017.04.027_bib0015","first-page":"N18","article-title":"Epidemiology of primary hyperparathyroidism in Europe","volume":"17","author":"Adami","year":"2002","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.surg.2017.04.027_bib0020","doi-asserted-by":"crossref","first-page":"433","DOI":"10.7326\/0003-4819-126-6-199703150-00003","article-title":"The rise and fall of primary hyperparathyroidism: a population-based study in Rochester, Minnesota, 1965\u20131992","volume":"126","author":"Wermers","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.surg.2017.04.027_bib0025","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s00268-002-6621-0","article-title":"Primary hyperparathyroidism revisited in menopausal women with serum calcium in the upper normal range at population-based screening 8 years ago","volume":"26","author":"Lundgren","year":"2002","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2017.04.027_bib0030","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1111\/joim.12523","article-title":"Genetics of parathyroid tumours","volume":"280","author":"Thakker","year":"2016","journal-title":"J Intern Med"},{"key":"10.1016\/j.surg.2017.04.027_bib0035","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.surg.2014.08.004","article-title":"Hyperparathyroidism-jaw tumor syndrome: results of operative management","volume":"156","author":"Mehta","year":"2014","journal-title":"Surgery"},{"issue":"suppl 5","key":"10.1016\/j.surg.2017.04.027_bib0040","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1245\/s10434-016-5467-x","article-title":"Reoperative surgery in patients with multiple endocrine neoplasia type 1 associated primary hyperparathyroidism","volume":"23","author":"Keutgen","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.surg.2017.04.027_bib0045","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1007\/s00268-012-1451-1","article-title":"Preoperative localizing studies for initial parathyroidectomy in MEN1 syndrome: is there any benefit?","volume":"36","author":"Nilubol","year":"2012","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2017.04.027_bib0050","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1245\/s10434-015-4865-9","article-title":"Limited parathyroidectomy in multiple endocrine neoplasia type 1-associated primary hyperparathyroidism: a setup for failure","volume":"23","author":"Nilubol","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.surg.2017.04.027_bib0055","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1210\/jc.2011-3030","article-title":"Sleeping parathyroid tumor: rapid hyperfunction after removal of the dominant tumor","volume":"97","author":"Yavuz","year":"2012","journal-title":"J Clin Endocrinol Metabol"},{"key":"10.1016\/j.surg.2017.04.027_bib0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00005792-200201000-00001","article-title":"Familial isolated hyperparathyroidism: clinical and genetic characteristics of 36 kindreds","volume":"81","author":"Simonds","year":"2002","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.surg.2017.04.027_bib0065","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1365-2265.2006.02438.x","article-title":"Genetic analyses in familial isolated hyperparathyroidism: implication for clinical assessment and surgical management","volume":"64","author":"Cetani","year":"2006","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.surg.2017.04.027_bib0070","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.ajhg.2016.08.018","article-title":"GCM2-activating mutations in familial isolated hyperparathyroidism","volume":"99","author":"Guan","year":"2016","journal-title":"J Hum Genet"},{"key":"10.1016\/j.surg.2017.04.027_bib0075","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s11864-004-0022-6","article-title":"Multiple endocrine neoplasia type 2","volume":"5","author":"Gertner","year":"2004","journal-title":"Curr Treat Options Oncol"},{"key":"10.1016\/j.surg.2017.04.027_bib0080","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1002\/(SICI)1097-0142(20000301)88:5<1139::AID-CNCR26>3.0.CO;2-Z","article-title":"Medullary thyroid carcinoma: clinical characteristics, treatment, prognostic factors, and a comparison of staging systems","volume":"88","author":"Kebebew","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.surg.2017.04.027_bib0085","first-page":"487","article-title":"Risk and penetrance of primary hyperparathyroidism in multiple endocrine neoplasia type 2A families with mutations at codon 634 of the RET proto-oncogene. Groupe D'etude des Tumeurs a Calcitonine","volume":"83","author":"Schuffenecker","year":"1998","journal-title":"J Clin Endocrinol Metabol"},{"key":"10.1016\/j.surg.2017.04.027_bib0090","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/0002-9343(74)90018-7","article-title":"Parathyroid carcinoma in familial hyperparathyroidism","volume":"57","author":"Mallette","year":"1974","journal-title":"Am J Med"},{"key":"10.1016\/j.surg.2017.04.027_bib0095","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1097\/SLA.0b013e31824c5145","article-title":"Primary hyperparathyroidism in MEN1 patients: a cohort study with longterm follow-up on preferred surgical procedure and the relation with genotype","volume":"255","author":"Pieterman","year":"2012","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2017.04.027_bib0100","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/35018111","article-title":"Genetic ablation of parathyroid glands reveals another source of parathyroid hormone","volume":"406","author":"Gunther","year":"2000","journal-title":"Nature"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606017305366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606017305366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,26]],"date-time":"2018-08-26T05:03:03Z","timestamp":1535259783000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606017305366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S0039606017305366"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2017.04.027","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Familial isolated primary hyperparathyroidism associated with germline GCM2 mutations is more aggressive and has a lesser rate of biochemical cure","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2017.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}