{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:07:23Z","timestamp":1785528443464,"version":"3.56.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["surgjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.surg.2018.04.027","type":"journal-article","created":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T00:26:55Z","timestamp":1529368015000},"page":"460-465","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Outcomes of appendectomy in elderly veteran patients"],"prefix":"10.1016","volume":"164","author":[{"given":"Oswaldo","family":"Renteria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zain","family":"Shahid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7720-419X","authenticated-orcid":false,"given":"Sergio","family":"Huerta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2018.04.027_bib0001","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1093\/oxfordjournals.aje.a115734","article-title":"The epidemiology of appendicitis and appendectomy in the United States","volume":"132","author":"Addiss","year":"1990","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.surg.2018.04.027_bib0002","unstructured":"U.S. Department of Health and Human Services, NFHS, National Health Statistics Reports. 2006 National Hospital Discharge Survey. 2008."},{"key":"10.1016\/j.surg.2018.04.027_bib0003","first-page":"489","article-title":"History of surgical treatment of appendicitis","volume":"62","author":"Meljnikov","year":"2009","journal-title":"Med Pregl"},{"key":"10.1016\/j.surg.2018.04.027_bib0004","first-page":"107","article-title":"Perforating inflammation of the veriform appendix with special reference to its early diagnosis and treatment","author":"Fitz","year":"1886","journal-title":"Trans Assoc Am Physicians"},{"key":"10.1016\/j.surg.2018.04.027_bib0005","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1136\/bmj.2.5007.1458","article-title":"Treatment of acute appendicitis","volume":"2","author":"Coldrey","year":"1956","journal-title":"Br Med J"},{"key":"10.1016\/j.surg.2018.04.027_bib0006","unstructured":"Combined traditional Chinese and western medicine inacute appendicitis. Chin Med J (Engl). 1977:266\u2013269."},{"key":"10.1016\/j.surg.2018.04.027_bib0007","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/milmed\/155.8.345","article-title":"The medical management of acute appendicitis in a nonsurgical environment: a retrospective case review","volume":"155","author":"Adams","year":"1990","journal-title":"Mil Med"},{"key":"10.1016\/j.surg.2018.04.027_bib0008","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s00268-005-0304-6","article-title":"Appendectomy versus antibiotic treatment in acute appendicitis. A prospective multicenter randomized controlled trial","volume":"30","author":"Styrud","year":"2006","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0009","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/bjs.6482","article-title":"Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients","volume":"96","author":"Hansson","year":"2009","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0010","first-page":"459","article-title":"Comparison of operative and nonoperative management of acute appendicitis","volume":"15","author":"Turhan","year":"2009","journal-title":"Ulus Travma Acil Cerrahi Derg"},{"key":"10.1016\/j.surg.2018.04.027_bib0011","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/S0140-6736(11)60410-8","article-title":"Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial","volume":"377","author":"Vons","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.surg.2018.04.027_bib0012","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1001\/jama.2015.6154","article-title":"Antibiotic therapy vs appendectomy for treatment of uncomplicated acute appendicitis: the APPAC randomized clinical trial","volume":"313","author":"Salminen","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.surg.2018.04.027_bib0013","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1055\/s-0032-1320014","article-title":"A review of conservative treatment of acute appendicitis","volume":"22","author":"Svensson","year":"2012","journal-title":"Eur J Pediatr Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0014","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/bjs.1800820207","article-title":"Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis","volume":"82","author":"Eriksson","year":"1995","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0015","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jinf.2014.08.009","article-title":"Appendicectomy for suspected uncomplicated appendicitis is associated with fewer complications than conservative antibiotic management: a meta-analysis of post-intervention complications","volume":"70","author":"Kirby","year":"2015","journal-title":"J Infect"},{"key":"10.1016\/j.surg.2018.04.027_bib0016","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.surg.2011.08.018","article-title":"Use of antibiotics alone for treatment of uncomplicated acute appendicitis: a systematic review and meta-analysis","volume":"150","author":"Liu","year":"2011","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2018.04.027_bib0017","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1089\/sur.2011.058","article-title":"Meta-analysis of randomized trials comparing antibiotic therapy with appendectomy for acute uncomplicated (no abscess or phlegmon) appendicitis","volume":"13","author":"Mason","year":"2012","journal-title":"Surg Infect (Larchmt)"},{"key":"10.1016\/j.surg.2018.04.027_bib0018","doi-asserted-by":"crossref","first-page":"e2156","DOI":"10.1136\/bmj.e2156","article-title":"Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials","volume":"344","author":"Varadhan","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.surg.2018.04.027_bib0019","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1503\/cjs.006610","article-title":"Antibiotics versus appendectomy in the management of acute appendicitis: a review of the current evidence","volume":"54","author":"Fitzmaurice","year":"2011","journal-title":"Can J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0020","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1002\/bjs.10147","article-title":"Meta-analysis of antibiotics versus appendicectomy for non-perforated acute appendicitis","volume":"103","author":"Sallinen","year":"2016","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0021","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.jamcollsurg.2016.09.005","article-title":"Nonoperative management of appendicitis in adults: a systematic review and meta-analysis of randomized controlled trials","volume":"223","author":"Findlay","year":"2016","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0022","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jamcollsurg.2015.11.009","article-title":"Evidence for an antibiotics-first strategy for uncomplicated appendicitis in adults: a systematic review and gap analysis","volume":"222","author":"Ehlers","year":"2016","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0023","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-016117","article-title":"Comparison of Outcomes of antibiotic Drugs and Appendectomy (CODA) trial: a protocol for the pragmatic randomised study of appendicitis treatment","volume":"7","author":"Davidson","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.surg.2018.04.027_bib0024","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1177\/000313481408000519","article-title":"Outcomes of emergent inguinal hernia repair in veteran octogenarians","volume":"80","author":"Huerta","year":"2014","journal-title":"Am Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0025","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1001\/archsurg.137.9.995","article-title":"Outcome of elderly patients with appendicitis: effect of computed tomography and laparoscopy","volume":"137","author":"Hui","year":"2002","journal-title":"Arch Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0026","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0027","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/SLE.0000000000000447","article-title":"Laparoscopic appendectomy for complicated acute appendicitis in the elderly: a single-center experience","volume":"27","author":"Yang","year":"2017","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"10.1016\/j.surg.2018.04.027_bib0028","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1177\/000313481708300740","article-title":"The utility of the Alvarado score in the diagnosis of acute appendicitis in the elderly","volume":"83","author":"Shchatsko","year":"2017","journal-title":"Am Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0029","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3393\/jksc.2011.27.5.241","article-title":"Laparoscopic versus open appendectomy for appendicitis in elderly patients","volume":"27","author":"Baek","year":"2011","journal-title":"J Korean Soc Coloproctol"},{"key":"10.1016\/j.surg.2018.04.027_bib0030","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s00068-016-0735-9","article-title":"Management, treatment and outcomes of acute appendicitis in an elderly population: a single-center experience","volume":"43","author":"Cohen-Arazi","year":"2017","journal-title":"Eur J Trauma Emerg Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0031","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0002-9610(06)80026-7","article-title":"A reappraisal of appendicitis in the elderly","volume":"160","author":"Horattas","year":"1990","journal-title":"Am J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0032","doi-asserted-by":"crossref","unstructured":"Storm-Dickerson TL, Horattas MC. What have we learned over the past 20 years about appendicitis in the elderly? Am J Surg 2003;185:198\u2013201.","DOI":"10.1016\/S0002-9610(02)01390-9"},{"key":"10.1016\/j.surg.2018.04.027_bib0033","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1007\/s00268-008-9916-y","article-title":"Value of laparoscopic appendectomy in the elderly patient","volume":"33","author":"Kirshtein","year":"2009","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0034","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.amjsurg.2017.07.039","article-title":"Operative versus non-operative management in the care of patients with complicated appendicitis","volume":"214","author":"Helling","year":"2017","journal-title":"Am J Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0035","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1097\/TA.0000000000001030","article-title":"Antibiotics for appendicitis! Not so fast","volume":"80","author":"Khalil","year":"2016","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1016\/j.surg.2018.04.027_bib0036","article-title":"Appendectomy versus antibiotic treatment for acute appendicitis","volume":"11","author":"Wilms","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.surg.2018.04.027_bib0037","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13017-017-0157-y","article-title":"The current management of acute uncomplicated appendicitis: should there be a change in paradigm? A systematic review of the literatures and analysis of treatment performance","volume":"12","author":"Poon","year":"2017","journal-title":"World J Emerg Surg"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003960601830196X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003960601830196X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T22:14:20Z","timestamp":1604441660000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003960601830196X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S003960601830196X"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2018.04.027","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes of appendectomy in elderly veteran patients","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2018.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}