{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:48:15Z","timestamp":1787878095707,"version":"build-2784847793"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surgjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.surg.2019.07.031","type":"journal-article","created":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T08:02:17Z","timestamp":1569312137000},"page":"358-364","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Recognition of primary hyperparathyroidism: Delayed time course from hypercalcemia to surgery"],"prefix":"10.1016","volume":"167","author":[{"given":"Robert","family":"Naples","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce J.","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren","family":"Berber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2804-3777","authenticated-orcid":false,"given":"Judy","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikram D.","family":"Krishnamurthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan E.","family":"Siperstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2019.07.031_bib1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1056\/NEJM198001243020402","article-title":"Primary hyperparathyroidism. Incidence, morbidity, and potential economic impact in a community","volume":"302","author":"Heath","year":"1980","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.surg.2019.07.031_bib2","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1016\/j.surg.2013.06.051","article-title":"The prevalence of undiagnosed and unrecognized primary hyperparathyroidism: A population-based analysis from the electronic medical record","volume":"154","author":"Press","year":"2013","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2019.07.031_bib3","doi-asserted-by":"crossref","first-page":"3561","DOI":"10.1210\/jc.2014-1413","article-title":"Guidelines for the management of asymptomatic primary hyperparathyroidism: Summary statement from the Fourth International Workshop","volume":"99","author":"Bilezikian","year":"2014","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib4","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/SLA.0000000000002474","article-title":"Surgery for primary hyperparathyroidism: Adherence to consensus guidelines in an academic health system","volume":"269","author":"Kuo","year":"2019","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2019.07.031_bib5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/BF01658740","article-title":"The influence of surgery on the risk of death in patients with primary hyperparathyroidism","volume":"15","author":"Hedback","year":"1991","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2019.07.031_bib6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0140-6736(87)91906-4","article-title":"Survival and renal function in untreated hypercalcemia. Population-based cohort study with 14 years of follow-up","volume":"1","author":"Palmer","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.surg.2019.07.031_bib7","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00268-002-6649-1","article-title":"Preoperative normal level of parathyroid hormone signifies an early and mild form of primary hyperparathyroidism","volume":"27","author":"Bergenfelz","year":"2003","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2019.07.031_bib8","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00774-015-0673-3","article-title":"Normocalcemic hyperparathyroidism is associated with complications similar to those of hypercalcemic hyperparathyroidism","volume":"34","author":"Tuna","year":"2016","journal-title":"J\u00a0Bone Miner Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib9","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1530\/EJE-09-1067","article-title":"Cardiovascular risk factors and arterial rigidity are similar in asymptomatic normocalcemic and hypercalcemic primary hyperparathyroidism","volume":"162","author":"Tordjman","year":"2010","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.surg.2019.07.031_bib10","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.surg.2011.09.011","article-title":"The phenotype of primary hyperparathyroidism with normal parathyroid hormone levels: How low can parathyroid hormone go?","volume":"150","author":"Wallace","year":"2011","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2019.07.031_bib11","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1245\/s10434-011-1744-x","article-title":"Normal PTH Levels in primary hyperparathyroidism: Still the same disease?","volume":"18","author":"Amin","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.surg.2019.07.031_bib12","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/BF03346443","article-title":"Cardiovascular aspects of primary hyperparathyroidism","volume":"31","author":"Walker","year":"2008","journal-title":"J\u00a0Endocrinol Invest"},{"key":"10.1016\/j.surg.2019.07.031_bib13","doi-asserted-by":"crossref","first-page":"3462","DOI":"10.1210\/jc.2007-1215","article-title":"The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15 years","volume":"93","author":"Rubin","year":"2008","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib14","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1056\/NEJM199910213411701","article-title":"A\u00a010-year prospective study of primary hyperparathyroidism with or without parathyroid surgery","volume":"341","author":"Silverberg","year":"1999","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.surg.2019.07.031_bib15","doi-asserted-by":"crossref","first-page":"715","DOI":"10.7326\/M15-1232","article-title":"The relationship of parathyroidectomy and bisphosphonates with fracture risk in primary hyperparathyroidism: an observational study","volume":"164","author":"Yeh","year":"2016","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.surg.2019.07.031_bib16","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1210\/jc.2008-1760","article-title":"Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop","volume":"94","author":"Silverberg","year":"2009","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib17","doi-asserted-by":"crossref","first-page":"3570","DOI":"10.1210\/jc.2014-1414","article-title":"Diagnosis of asymptomatic primary hyperparathyroidism: Proceedings of the Fourth International Workshop","volume":"99","author":"Eastell","year":"2014","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib18","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jamasurg.2016.2310","article-title":"The American Association of Endocrine Surgeons guidelines for definitive management of primary hyperparathyroidism","volume":"151","author":"Wilhelm","year":"2016","journal-title":"JAMA Surg"},{"key":"10.1016\/j.surg.2019.07.031_bib19","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1210\/jc.2007-0219","article-title":"Surgery or surveillance for mild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trial","volume":"92","author":"Ambrogini","year":"2007","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib20","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1210\/jc.2006-1836","article-title":"Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trial","volume":"92","author":"Bollerslev","year":"2007","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib21","doi-asserted-by":"crossref","first-page":"5415","DOI":"10.1210\/jc.2004-0028","article-title":"Randomized controlled clinical trial of surgery versus no surgery in patients with mild asymptomatic primary hyperparathyroidism","volume":"89","author":"Rao","year":"2004","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib22","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1210\/jc.2011-0569","article-title":"Nephrolithiasis and renal calcifications in primary hyperparathyroidism","volume":"96","author":"Rejnmark","year":"2011","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib23","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ucl.2007.04.009","article-title":"Pathophysiology and management of calcium stones","volume":"34","author":"Park","year":"2007","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.surg.2019.07.031_bib24","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0272-6386(12)80602-0","article-title":"Etiology and treatment of urolithiasis","volume":"18","author":"Pak","year":"1991","journal-title":"Am J Kidney Disease"},{"key":"10.1016\/j.surg.2019.07.031_bib25","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.surg.2016.09.012","article-title":"Concentration of serum calcium is not correlate with symptoms of severity of primary hyperparathyroidism: An examination of 20,081 consecutive adults","volume":"161","author":"Boone","year":"2017","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2019.07.031_bib26","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1365-2796.1990.tb00166.x","article-title":"Pre- and postoperative evaluation of renal function with five different tests in patients with primary hyperparathyroidism","volume":"227","author":"Kristoffersson","year":"1990","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.surg.2019.07.031_bib27","doi-asserted-by":"crossref","first-page":"4458","DOI":"10.1210\/jc.2009-0587","article-title":"Glomerular filtration rate and parathyroid hormone secretion in primary hyperparathyroidism","volume":"94","author":"Tassone","year":"2009","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib28","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3121\/cmr.2013.1164","article-title":"24-hour urinary calcium in primary hyparathyroidism","volume":"11","author":"Black","year":"2013","journal-title":"Clin Med Res"},{"key":"10.1016\/j.surg.2019.07.031_bib29","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1210\/jc.2015-2132","article-title":"Parathyroidectomy halts the deterioration of renal function in primary hyperparathyroidism","volume":"100","author":"Tassone","year":"2015","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.surg.2019.07.031_bib30","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3906\/sag-1806-181","article-title":"Factors associated with glomerular filtration rate\u00a0variation in primary hyperparathyroidism","volume":"49","author":"Caliskan","year":"2019","journal-title":"Turk J Med Sci"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606019305677?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606019305677?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T10:52:08Z","timestamp":1758538328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606019305677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0039606019305677"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2019.07.031","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recognition of primary hyperparathyroidism: Delayed time course from hypercalcemia to surgery","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2019.07.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}