{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:07:08Z","timestamp":1786997228635,"version":"build-2736575974"},"reference-count":24,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surgjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.surg.2021.10.016","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:12:33Z","timestamp":1634825553000},"page":"1422-1426","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["The catastrophic impact of COVID-19 infection in patients with chronic limb-threatening ischemia"],"prefix":"10.1016","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7646-5208","authenticated-orcid":false,"given":"Rafael","family":"de Athayde Soares","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayara","family":"de Arruda C\u00e1ceres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anndya Gon\u00e7alves","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Fernando","family":"Matielo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Sacilotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2021.10.016_bib1","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1007\/s00134-020-05991-x","article-title":"Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China","volume":"46","author":"Ruan","year":"2020","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.surg.2021.10.016_bib2","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1001\/jamacardio.2020.0950","article-title":"Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China","volume":"5","author":"Shi","year":"2020","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.surg.2021.10.016_bib3","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.jvs.2011.08.014","article-title":"Long-term results of direct and indirect endovascular revascularization based on the angiosome concept in patients with critical limb ischemia presenting with isolated below-the-knee lesions","volume":"55","author":"Iida","year":"2012","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cell.2020.02.052","article-title":"SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor","volume":"18","author":"Hoffmann","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.surg.2021.10.016_bib5","first-page":"575","article-title":"Characteristics of and public health responses to the coronavirus disease 2019 outbreak in China","volume":"9","author":"Deng","year":"2020","journal-title":"J\u00a0Clin Med"},{"key":"10.1016\/j.surg.2021.10.016_bib6","article-title":"COVID-19 diagnosis in a patient with critical limb ischemia: complications and clinical outcomes","volume":"19","author":"Soares","year":"2020","journal-title":"J\u00a0Vasc Bras"},{"key":"10.1016\/j.surg.2021.10.016_bib7","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","article-title":"China Medical Treatment Expert Group for COVID-19: clinical characteristics of coronavirus disease 2019 in China","volume":"382","author":"Guan","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.surg.2021.10.016_bib8","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.jvs.2020.04.483","article-title":"Acute limb ischemia in patients with COVID-19 pneumonia","volume":"72","author":"Bellosta","year":"2020","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib9","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1016\/j.jvs.2018.01.060","article-title":"The Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification system predicts wound healing better than direct angiosome perfusion in diabetic foot wounds","volume":"68","author":"Weaver","year":"2018","journal-title":"J\u00a0Vasc Surg"},{"issue":"1S","key":"10.1016\/j.surg.2021.10.016_bib10","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"58","author":"Conte","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib11","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.jvs.2020.04.489","article-title":"An increased severity of peripheral arterial disease in the COVID-19 era foot wounds","volume":"72","author":"Sena","year":"2020","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib12","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.avsg.2020.07.049","article-title":"WIfI classification versus angiosome concept: a change in the infrapopliteal angioplasties paradigm","volume":"71","author":"De Athayde Soares","year":"2021","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib13","article-title":"Impact of calcification and infrapopliteal outflow on the outcome of endovascular treatment of\u00a0femoropopliteal occlusive disease","volume":"8","author":"de Athayde Soares","year":"2019","journal-title":"JRSM Cardiovasc Dis"},{"key":"10.1016\/j.surg.2021.10.016_bib14","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jvs.2016.04.020","article-title":"Number of infrapopliteal arteries undergoing endovascular treatment is not associated with the limb salvage rate in patients with critical limb ischemia","volume":"64","author":"de Athayde Soares","year":"2016","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib15","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/jth.14768","article-title":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia","volume":"18","author":"Tang","year":"2020","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.surg.2021.10.016_bib16","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jvs.2013.08.003","article-title":"The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: risk stratification based on wound, ischemia, and foot infection (WIfI)","volume":"59","author":"Mills","year":"2014","journal-title":"J\u00a0Vasc Surg"},{"issue":"6S","key":"10.1016\/j.surg.2021.10.016_bib17","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"69","author":"Conte","year":"2019","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.surg.2021.10.016_bib18","doi-asserted-by":"crossref","unstructured":"Shi C, Wang C, Wang H, et\u00a0al. The potential of low molecular weight heparin to mitigate cytokine storm in severe COVID-19 patients: a retrospective clinical study. medRxiv. 2020 2020.2003.2028.20046144.","DOI":"10.1101\/2020.03.28.20046144"},{"key":"10.1016\/j.surg.2021.10.016_bib19","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1056\/NEJMc2007575","article-title":"Coagulopathy and antiphospholipid antibodies in patients with COVID-19","volume":"382","author":"Zhang","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.surg.2021.10.016_bib20","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1080\/17474086.2020.1831383","article-title":"D-dimer level in COVID-19 infection: a systematic review","volume":"13","author":"Rostami","year":"2020","journal-title":"Expert Rev Hematol"},{"key":"10.1016\/j.surg.2021.10.016_bib21","unstructured":"Lopes RD, Furtado RHM, Macedo AVS, et\u00a0al. Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial. Lancet. 397:2253\u20132263."},{"key":"10.1016\/j.surg.2021.10.016_bib22","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1080\/0886022X.2020.1756323","article-title":"Survival rate in acute kidney injury superimposed COVID-19 patients: a systematic review and meta-analysis","volume":"42","author":"Ali","year":"2020","journal-title":"Ren Fail"},{"key":"10.1016\/j.surg.2021.10.016_bib23","first-page":"1","article-title":"Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection","author":"Henry","year":"2020","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.surg.2021.10.016_bib24","first-page":"100109","article-title":"Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform","volume":"6","author":"Bhaskaran","year":"2021","journal-title":"Lancet"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606021009764?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606021009764?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T11:01:02Z","timestamp":1758538862000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606021009764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S0039606021009764"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2021.10.016","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The catastrophic impact of COVID-19 infection in patients with chronic limb-threatening ischemia","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2021.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}