{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:35:58Z","timestamp":1792683358194,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","surgjournal.com","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.surg.2024.02.032","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T05:30:18Z","timestamp":1712640618000},"page":"162-171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["The role of procalcitonin as a risk stratification tool of severity, prognosis, and need for surgery in patients with acute left-sided colonic diverticulitis"],"prefix":"10.1016","volume":"176","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1136-1103","authenticated-orcid":false,"given":"Carlo Alberto","family":"Schena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Covino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0040-684X","authenticated-orcid":false,"given":"Vito","family":"Laterza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Quero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"La Greca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Cina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"de\u2019Angelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5312-8054","authenticated-orcid":false,"given":"Francesco","family":"Marchegiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Sganga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Gasbarrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Franceschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Longo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Alfieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7280-8354","authenticated-orcid":false,"given":"Fausto","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2024.02.032_bib1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/j.1463-1318.2006.01162.x","article-title":"Acute diverticulitis: clinical presentation and differential diagnostics","volume":"9","author":"Laurell","year":"2007","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1159\/000509049","article-title":"Acute diverticulitis in elderly patients: does age really matter?","volume":"39","author":"Covino","year":"2021","journal-title":"Dig Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib3","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1007\/BF02236921","article-title":"Diverticular disease of the colon: a century-old problem","volume":"42","author":"Schoetz","year":"1999","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.surg.2024.02.032_bib4","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.cgh.2013.06.020","article-title":"Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy","volume":"11","author":"Shahedi","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.surg.2024.02.032_bib5","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/MCG.0000000000000308","article-title":"Modern concepts in diverticular disease","volume":"49","author":"Collins","year":"2015","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.surg.2024.02.032_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1155\/2007\/943460","article-title":"Fourteen-year study of hospital admissions for diverticular disease in Ontario","volume":"21","author":"Warner","year":"2007","journal-title":"Can J Gastroenterol"},{"key":"10.1016\/j.surg.2024.02.032_bib7","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s00384-014-1888-9","article-title":"Major increase in admission\u2014and incidence rates of acute colonic diverticulitis","volume":"29","author":"Jamal Talabani","year":"2014","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib8","first-page":"85","article-title":"Treatment of perforated diverticular disease of the colon","volume":"12","author":"Hinchey","year":"1978","journal-title":"Adv Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib9","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1111\/j.1572-0241.2005.41154.x","article-title":"The management of complicated diverticulitis and the role of computed tomography","volume":"100","author":"Kaiser","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.surg.2024.02.032_bib10","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1007\/s00330-001-1143-y","article-title":"Colonic diverticulitis: impact of imaging on surgical management: a prospective study of 542 patients","volume":"12","author":"Ambrosetti","year":"2002","journal-title":"Eur Radiol"},{"key":"10.1016\/j.surg.2024.02.032_bib11","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1111\/codi.12449","article-title":"Application of a modified Neff classification to patients with uncomplicated diverticulitis","volume":"15","author":"Mora Lopez","year":"2013","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib12","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0033-8389(22)02158-3","article-title":"CT of diverticulitis: diagnosis and treatment","volume":"27","author":"Neff","year":"1989","journal-title":"Radiol Clin North Am"},{"key":"10.1016\/j.surg.2024.02.032_bib13","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13017-020-00313-4","article-title":"2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting","volume":"15","author":"Sartelli","year":"2020","journal-title":"World J Emerg Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13017-016-0095-0","article-title":"WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting","volume":"11","author":"Sartelli","year":"2016","journal-title":"World J Emerg Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib15","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1097\/SLA.0b013e3182113614","article-title":"How to diagnose acute left-sided colonic diverticulitis: proposal for a clinical scoring system","volume":"253","author":"Andeweg","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib16","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1177\/000313481408000423","article-title":"The role of C-reactive protein in the prediction of the clinical severity of acute diverticulitis","volume":"80","author":"Kechagias","year":"2014","journal-title":"Am Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib17","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/codi.12072","article-title":"The value of inflammation markers and body temperature in acute diverticulitis","volume":"15","author":"van de Wall","year":"2013","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib18","doi-asserted-by":"crossref","first-page":"536","DOI":"10.3109\/00365521.2014.999350","article-title":"The role of C-reactive protein in prediction of the severity of acute diverticulitis in an emergency unit","volume":"50","author":"Makela","year":"2015","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.surg.2024.02.032_bib19","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.2147\/TCRM.S160113","article-title":"Index C-reactive protein predicts increased severity in acute sigmoid diverticulitis","volume":"14","author":"Kechagias","year":"2018","journal-title":"Ther Clin Risk Manag"},{"key":"10.1016\/j.surg.2024.02.032_bib20","first-page":"345","article-title":"C-reactive protein and the acute phase response","volume":"27","author":"Gewurz","year":"1982","journal-title":"Adv Intern Med"},{"key":"10.1016\/j.surg.2024.02.032_bib21","first-page":"CD007498","article-title":"Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections","volume":"10","author":"Schuetz","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.surg.2024.02.032_bib22","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0140-6736(93)90277-N","article-title":"High serum procalcitonin concentrations in patients with sepsis and infection","volume":"341","author":"Assicot","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.surg.2024.02.032_bib23","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1186\/s13054-015-1093-4","article-title":"Inflammatory mediators in intra-abdominal sepsis or injury: a scoping review","volume":"19","author":"Xiao","year":"2015","journal-title":"Crit Care"},{"key":"10.1016\/j.surg.2024.02.032_bib24","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/s13054-018-2125-7","article-title":"Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials","volume":"22","author":"Wirz","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.surg.2024.02.032_bib25","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/bjs.9008","article-title":"Systematic review and meta-analysis of the diagnostic accuracy of procalcitonin, C-reactive protein and white blood cell count for suspected acute appendicitis","volume":"100","author":"Yu","year":"2013","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib26","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/0895-4356(94)90129-5","article-title":"Validation of a combined comorbidity index","volume":"47","author":"Charlson","year":"1994","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.surg.2024.02.032_bib27","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/MLR.0000000000000905","article-title":"Validation of the Combined Comorbidity Index of Charlson and Elixhauser to predict 30-day mortality across ICD-9 and ICD-10","volume":"56","author":"Simard","year":"2018","journal-title":"Med Care"},{"key":"10.1016\/j.surg.2024.02.032_bib28","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.3390\/antibiotics11101315","article-title":"Antimicrobial challenge in acute care surgery","volume":"11","author":"Schena","year":"2022","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.surg.2024.02.032_bib29","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.mayocp.2016.03.012","article-title":"Diverticulosis and diverticulitis","volume":"91","author":"Feuerstein","year":"2016","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.surg.2024.02.032_bib30","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1053\/j.gastro.2015.10.003","article-title":"American Gastroenterological Association Institute guideline on the management of acute diverticulitis","volume":"149","author":"Stollman","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.surg.2024.02.032_bib31","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1001\/jama.2013.282025","article-title":"Sigmoid diverticulitis: a systematic review","volume":"311","author":"Morris","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.surg.2024.02.032_bib32","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1007\/s00384-017-2872-y","article-title":"Risk factors for complicated diverticulitis: systematic review and meta-analysis","volume":"32","author":"Bolkenstein","year":"2017","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib33","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1007\/s00268-010-0726-7","article-title":"Diagnostic value of inflammation markers in predicting perforation in acute sigmoid diverticulitis","volume":"34","author":"Kaser","year":"2010","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib34","first-page":"325","article-title":"Hyperbilirubinemia as a predictor of gangrenous\/perforated appendicitis: a prospective study","volume":"26","author":"Chaudhary","year":"2013","journal-title":"Ann Gastroenterol"},{"key":"10.1016\/j.surg.2024.02.032_bib35","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1159\/000450836","article-title":"The utility of neutrophil to lymphocyte ratio as a predictor of intervention in acute diverticulitis","volume":"34","author":"Reynolds","year":"2017","journal-title":"Dig Surg"},{"issue":"Suppl 1","key":"10.1016\/j.surg.2024.02.032_bib36","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1097\/MCG.0000000000000648","article-title":"The role of biomarkers in diverticular disease","volume":"50","author":"Gallo","year":"2016","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.surg.2024.02.032_bib37","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1007\/s00423-021-02252-3","article-title":"Role of serum procalcitonin in predicting the surgical outcomes of acute calculous cholecystitis","volume":"406","author":"Fransvea","year":"2021","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.surg.2024.02.032_bib38","first-page":"132","article-title":"Factors predicting severity level, progression and recurrence risk of acute left colonic diverticulitis in Turkey: a multicenter study","volume":"27","author":"Sagiroglu","year":"2021","journal-title":"Ulus Travma Acil Cerrahi Derg"},{"key":"10.1016\/j.surg.2024.02.032_bib39","doi-asserted-by":"crossref","first-page":"5852","DOI":"10.1002\/jcb.27870","article-title":"The diagnostic accuracy of procalcitonin and C-reactive protein for sepsis: a systematic review and meta-analysis","volume":"120","author":"Tan","year":"2019","journal-title":"J\u00a0Cell Biochem"},{"key":"10.1016\/j.surg.2024.02.032_bib40","article-title":"Using procalcitonin to guide antibiotic therapy","volume":"4","author":"Rhee","year":"2016","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.surg.2024.02.032_bib41","article-title":"Is there a role for procalcitonin in differentiating uncomplicated and complicated diverticulitis in order to reduce antibiotic therapy? A prospective diagnostic cohort study","volume":"147","author":"Jeger","year":"2017","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.surg.2024.02.032_bib42","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1186\/s13054-018-2234-3","article-title":"Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands","volume":"22","author":"Kip","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.surg.2024.02.032_bib43","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1515\/cclm-2014-1015","article-title":"Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective","volume":"53","author":"Schuetz","year":"2015","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.surg.2024.02.032_bib44","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1097\/CCM.0b013e31821201a5","article-title":"Procalcitonin for reduced antibiotic exposure in the critical care setting: a systematic review and an economic evaluation","volume":"39","author":"Heyland","year":"2011","journal-title":"Crit Care Med"},{"key":"10.1016\/j.surg.2024.02.032_bib45","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s11606-013-2679-7","article-title":"Cost-effectiveness of procalcitonin-guided antibiotic therapy for outpatient management of acute respiratory tract infections in adults","volume":"29","author":"Michaelidis","year":"2014","journal-title":"J\u00a0Gen Intern Med"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606024001363?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606024001363?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T02:43:01Z","timestamp":1717728181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606024001363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S0039606024001363"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2024.02.032","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of procalcitonin as a risk stratification tool of severity, prognosis, and need for surgery in patients with acute left-sided colonic diverticulitis","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2024.02.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}