{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T08:59:38Z","timestamp":1780822778030,"version":"3.54.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surgjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.surg.2025.109815","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:56:18Z","timestamp":1761303378000},"page":"109815","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Prophylactic abdominal drainage does not reduce morbidity and mortality after distal pancreatectomy: A systematic review and meta-analysis of randomized controlled trials"],"prefix":"10.1016","volume":"190","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6638-4479","authenticated-orcid":false,"given":"Claudio","family":"Ricci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Alberici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"D'Ambra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Ingaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Fichera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Casadei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2025.109815_bib1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.surg.2021.11.023","article-title":"Drain use in pancreatic surgery: results from an international survey among experts in the field","volume":"172","author":"Pergolini","year":"2022","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2025.109815_bib2","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.surg.2016.11.014","article-title":"The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years after","volume":"161","author":"Bassi","year":"2017","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2025.109815_bib3","article-title":"Postoperative pancreatic fistula: focus should be shifted from early drain removal to early management","volume":"6","author":"van Santvoort","year":"2023","journal-title":"BJS Open"},{"key":"10.1016\/j.surg.2025.109815_bib4","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.surg.2007.02.001","article-title":"Postpancreatectomy hemorrhage (PPH): an international study group of pancreatic surgery (ISGPS) definition","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2025.109815_bib5","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/bjs.10505","article-title":"Meta-analysis of prophylactic abdominal drainage in pancreatic surgery","volume":"104","author":"H\u00fcttner","year":"2017","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2025.109815_bib6","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/SLA.0000000000002375","article-title":"A prospective randomized multicenter trial of distal pancreatectomy with and without routine intraperitoneal drainage","volume":"266","author":"Van Buren","year":"2017","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2025.109815_bib7","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s13304-024-01836-0","article-title":"Intraperitoneal prophylactic drain after pancreaticoduodenectomy: an Italian survey","volume":"76","author":"Ricci","year":"2024","journal-title":"Updates Surg"},{"key":"10.1016\/j.surg.2025.109815_bib8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s13304-024-01987-0","article-title":"Italian survey about intraperitoneal drain use in distal pancreatectomy","volume":"77","author":"Pecorelli","year":"2024","journal-title":"Updates Surg"},{"key":"10.1016\/j.surg.2025.109815_bib9","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/S2468-1253(24)00037-2","article-title":"Prophylactic abdominal drainage after distal pancreatectomy (PANDORINA): an international, multicentre, open-label, randomised controlled, non-inferiority trial","volume":"9","author":"van Bodegraven","year":"2024","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.surg.2025.109815_bib10","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/SLA.0000000000006651","article-title":"Reconsidering abdominal drainage after left pancreatectomy - the randomized controlled PANDRA II trial","volume":"282","author":"Kaiser","year":"2025","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2025.109815_bib11","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.surg.2025.109815_bib12","doi-asserted-by":"crossref","first-page":"420","DOI":"10.5195\/jmla.2018.345","article-title":"The impact of patient, intervention, comparison, outcome (PICO) as a search strategy tool on literature search quality: a systematic review","volume":"106","author":"Eriksen","year":"2018","journal-title":"J Med Libr Assoc"},{"key":"10.1016\/j.surg.2025.109815_bib13","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.surg.2025.109815_bib14","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.1445-2197.2011.05830.x","article-title":"Usefulness of the Clavien\u2013Dindo classification after pancreaticoduodenectomy","volume":"81","author":"Casadei","year":"2011","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.surg.2025.109815_bib15","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.surg.2007.05.005","article-title":"Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2025.109815_bib16","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.surg.2025.109815_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/1471-2288-5-13","article-title":"Estimating the mean and variance from the median, range, and the size of a sample","volume":"5","author":"Hozo","year":"2005","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.surg.2025.109815_bib18","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.surg.2025.109815_bib19","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.jclinepi.2008.09.018","article-title":"Cochrane reviews used more rigorous methods than non-Cochrane reviews: survey of systematic reviews in physiotherapy","volume":"62","author":"Moseley","year":"2009","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.surg.2025.109815_bib20","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.surg.2025.109815_bib21","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.surg.2025.109815_bib22","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1002\/(SICI)1097-0258(19991030)18:20<2693::AID-SIM235>3.0.CO;2-V","article-title":"Explaining heterogeneity in meta-analysis: a comparison of methods","volume":"18","author":"Thompson","year":"1999","journal-title":"Stat Med"},{"key":"10.1016\/j.surg.2025.109815_bib23","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1002\/sim.1752","article-title":"Controlling the risk from spurious findings from meta-regression","volume":"23","author":"Higgins","year":"2004","journal-title":"Stat Med"},{"key":"10.1016\/j.surg.2025.109815_bib24","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.surg.2025.109815_bib25","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.amjsurg.2019.05.006","article-title":"Prophylactic intra-abdominal drainage following colorectal anastomoses. A systematic review and meta-analysis of randomized controlled trials","volume":"219","author":"Podda","year":"2020","journal-title":"Am J Surg"},{"key":"10.1016\/j.surg.2025.109815_bib26","article-title":"Abdominal drainage versus no drainage post-gastrectomy for gastric cancer","volume":"2015","author":"Wang","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.surg.2025.109815_bib27","article-title":"Routine abdominal drainage for uncomplicated liver resection","volume":"18","author":"Gurusamy","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.surg.2025.109815_bib28","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s00268-018-4844-y","article-title":"Guidelines for perioperative care in elective colorectal surgery: enhanced recovery after surgery (ERAS\u00ae) society recommendations: 2018","volume":"43","author":"Gustafsson","year":"2019","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2025.109815_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00268-022-06732-5","article-title":"Guidelines for perioperative care for liver surgery: enhanced recovery after surgery (ERAS) society recommendations 2022","volume":"47","author":"Joliat","year":"2023","journal-title":"World J Surg"},{"key":"10.1016\/j.surg.2025.109815_bib30","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1007\/s00595-021-02287-5","article-title":"Causative bacteria associated with a clinically relevant postoperative pancreatic fistula infection after distal pancreatectomy","volume":"51","author":"Osakabe","year":"2021","journal-title":"Surg Today"},{"key":"10.1016\/j.surg.2025.109815_bib31","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1245\/s10434-024-14959-w","article-title":"Early versus late drainage removal in patients who underwent pancreaticoduodenectomy: a comprehensive systematic review and meta-analysis of randomized controlled trials using trial sequential analysis","volume":"31","author":"Ricci","year":"2024","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.surg.2025.109815_bib33","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/SLA.0b013e3181e89e1e","article-title":"Pancreatic surgery 101: drain, no drain, early drain removal, or late drain removal. What are the data? Where do we go from here?","volume":"252","year":"2010","journal-title":"Ann Surg"},{"key":"10.1016\/j.surg.2025.109815_bib32","doi-asserted-by":"crossref","DOI":"10.1093\/bjs\/znae039","article-title":"Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus","volume":"111","author":"van Ramshorst","year":"2024","journal-title":"Br J Surg"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606025006671?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606025006671?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T08:22:05Z","timestamp":1780820525000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606025006671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":33,"alternative-id":["S0039606025006671"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2025.109815","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prophylactic abdominal drainage does not reduce morbidity and mortality after distal pancreatectomy: A systematic review and meta-analysis of randomized controlled trials","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2025.109815","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"109815"}}