{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:10:23Z","timestamp":1789506623594,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surgjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgery"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.surg.2026.110421","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:28:20Z","timestamp":1782491300000},"page":"110421","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Comparison of anastomotic patency and remnant pancreatic function between invagination and duct-to-mucosa pancreaticojejunostomy: A follow-up study of a randomized trial"],"prefix":"10.1016","volume":"198","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3416-7047","authenticated-orcid":false,"given":"Hidenori","family":"Ojio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Natsume","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonari","family":"Asano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Okuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nozomi","family":"Okuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keitaro","family":"Matsuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Komori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surg.2026.110421_bib1","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1002\/bjs.9252","article-title":"Randomized clinical trial of pancreaticogastrostomy versus pancreaticojejunostomy on the rate and severity of pancreatic fistula after pancreaticoduodenectomy","volume":"100","author":"Figueras","year":"2013","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2026.110421_bib2","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1002\/bjs.9553","article-title":"Meta-analysis of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy","volume":"101","author":"Xiong","year":"2014","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2026.110421_bib3","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1007\/BF00311562","article-title":"A simpler and more reliable technique of pancreatojejunal anastomosis","volume":"26","author":"Kakita","year":"1996","journal-title":"Surg Today"},{"key":"10.1016\/j.surg.2026.110421_bib4","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jamcollsurg.2009.09.020","article-title":"Novel pancreaticojejunostomy with a low rate of anastomotic failure-related complications","volume":"210","author":"Grobmyer","year":"2010","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.surg.2026.110421_bib5","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1007\/s11605-014-2523-3","article-title":"Modified Blumgart anastomosis for pancreaticojejunostomy: technical improvement in matched historical control study","volume":"18","author":"Fujii","year":"2014","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.surg.2026.110421_bib6","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/bjs.10727","article-title":"Randomized clinical trial of duct-to-mucosa versus invagination pancreaticojejunostomy after pancreatoduodenectomy","volume":"105","author":"Senda","year":"2018","journal-title":"Br J Surg"},{"key":"10.1016\/j.surg.2026.110421_bib7","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1016\/j.hpb.2022.08.013","article-title":"Impact of pancreatic fat infiltration on postoperative pancreatic fistula occurrence in patients undergoing invagination pancreaticojejunostomy","volume":"24","author":"Dei","year":"2022","journal-title":"HPB (Oxford)"},{"key":"10.1016\/j.surg.2026.110421_bib8","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/jhbp.799","article-title":"Risk factors for pancreatic fistula grade C after pancreatoduodenectomy: a large prospective, multicenter Japan-Taiwan collaboration study","volume":"27","author":"Hirono","year":"2020","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"10.1016\/j.surg.2026.110421_bib9","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1007\/s11605-020-04641-3","article-title":"Long-term surgical complications after pancreatoduodenectomy: incidence, outcomes, and risk factors","volume":"24","author":"Brown","year":"2020","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.surg.2026.110421_bib10","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.pan.2023.05.010","article-title":"A comparative study between computed tomography and endoscopic ultrasound in the detection of a mural nodule in intraductal papillary mucinous neoplasm - multicenter observational study in Japan","volume":"23","author":"Kin","year":"2023","journal-title":"Pancreatology"},{"key":"10.1016\/j.surg.2026.110421_bib11","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/den.13408","article-title":"Usefulness of septal thickness measurement on endoscopic ultrasound as a predictor of malignancy of branched-duct and mixed-type intraductal papillary mucinous neoplasm of the pancreas","volume":"31","author":"Iwaya","year":"2019","journal-title":"Dig Endosc"},{"key":"10.1016\/j.surg.2026.110421_bib12","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S0140-6736(16)30583-9","article-title":"Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01)","volume":"388","author":"Uesaka","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.surg.2026.110421_bib13","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/jjco\/hyy190","article-title":"Randomized phase II\/III trial of neoadjuvant chemotherapy with gemcitabine and S-1 versus upfront surgery for resectable pancreatic cancer (Prep-02\/JSAP05)","volume":"49","author":"Motoi","year":"2019","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.surg.2026.110421_bib14","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0140-6736(22)02038-4","article-title":"Adjuvant S-1 compared with observation in resected biliary tract cancer (JCOG1202, ASCOT): a multicentre, open-label, randomised, controlled, phase 3 trial","volume":"401","author":"Nakachi","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.surg.2026.110421_bib15","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.surg.2016.11.014","article-title":"The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after","volume":"161","author":"Bassi","year":"2017","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2026.110421_bib16","first-page":"234","volume":"51","author":"Mizuma","year":"2013","journal-title":"Nihon Shoukaki Gan Kenshin Gakkai zasshi"},{"key":"10.1016\/j.surg.2026.110421_bib17","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/XCS.0000000000001121","article-title":"Clinical implications and risk factors of dilatation of remnant pancreatic duct at 1 year after pancreatoduodenectomy: a prospective, Japanese, multicenter, observational cohort study (DAIMONJI Study)","volume":"239","author":"Narita","year":"2024","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.surg.2026.110421_bib18","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1097\/01.TP.0000140499.23683.0D","article-title":"Noninvasive evaluation of graft steatosis in living donor liver transplantation","volume":"78","author":"Iwasaki","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.surg.2026.110421_bib19","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1111\/jdi.13306","article-title":"Japanese clinical practice guideline for diabetes 2019","volume":"11","author":"Araki","year":"2020","journal-title":"J Diabetes Investig"},{"key":"10.1016\/j.surg.2026.110421_bib20","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1214\/aos\/1176350951","article-title":"A class of k-sample tests for comparing the cumulative incidence of a competing risk","volume":"16","author":"Gray","year":"1988","journal-title":"Ann Stat"},{"key":"10.1016\/j.surg.2026.110421_bib21","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/sj.bmt.1705727","article-title":"Competing risk analysis using R: an easy guide for clinicians","volume":"40","author":"Scrucca","year":"2007","journal-title":"Bone Marrow Transpl"},{"key":"10.1016\/j.surg.2026.110421_bib22","first-page":"30","article-title":"A dog model of pancreaticojejunostomy without duct-to-mucosa anastomosis","volume":"13","author":"Choi","year":"2012","journal-title":"JOP"},{"key":"10.1016\/j.surg.2026.110421_bib23","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.pan.2017.06.008","article-title":"Long-term outcomes after pancreaticoduodenectomy using pair-watch suturing technique: different roles of pancreatic duct dilatation and remnant pancreatic volume for the development of pancreatic endocrine and exocrine dysfunction","volume":"17","author":"Iizawa","year":"2017","journal-title":"Pancreatology"},{"key":"10.1016\/j.surg.2026.110421_bib24","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1007\/s11605-018-3859-x","article-title":"Late pancreaticanastomosis stricture following pancreaticoduodenectomy: a systematic review","volume":"22","author":"Zarzavadjian Le Bian","year":"2018","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.surg.2026.110421_bib25","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/clinchem\/42.2.222","article-title":"Immunoreactive elastase 1: clinical evaluation of a new noninvasive test of pancreatic function","volume":"42","author":"Stein","year":"1996","journal-title":"Clin Chem"},{"key":"10.1016\/j.surg.2026.110421_bib26","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0016-5085(91)80024-4","article-title":"Studies on the sterol-binding capacity of human pancreatic elastase 1","volume":"100","author":"Sziegoleit","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1016\/j.surg.2026.110421_bib27","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1159\/000158596","article-title":"Pancreatic fibrosis correlates with exocrine pancreatic insufficiency after pancreatoduodenectomy","volume":"25","author":"Tran","year":"2008","journal-title":"Dig Surg"},{"key":"10.1016\/j.surg.2026.110421_bib28","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.3748\/wjg.14.3149","article-title":"Pancreatic function testing: here to stay for the 21st century","volume":"14","author":"Lieb","year":"2008","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.surg.2026.110421_bib29","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.surg.2008.08.013","article-title":"Usefulness of a 13C-labeled mixed triglyceride breath test for assessing pancreatic exocrine function after pancreatic surgery","volume":"145","author":"Nakamura","year":"2009","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2026.110421_bib30","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.surg.2015.08.046","article-title":"Remnant pancreatic parenchymal volume predicts postoperative pancreatic exocrine insufficiency after pancreatectomy","volume":"159","author":"Okano","year":"2016","journal-title":"Surgery"},{"key":"10.1016\/j.surg.2026.110421_bib31","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/jso.23693","article-title":"Nonalcoholic fatty liver disease after pancreatoduodenectomy is closely associated with postoperative pancreatic exocrine insufficiency","volume":"110","author":"Nakagawa","year":"2014","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.surg.2026.110421_bib32","first-page":"4310","article-title":"Long-term pancreatic exocrine and endometabolic functionality after pancreaticoduodenectomy. Comparison between pancreaticojejunostomy and pancreatic duct occlusion with fibrin glue","volume":"22","author":"Alfieri","year":"2018","journal-title":"Eur Rev Med Pharmacol Sci"}],"container-title":["Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606026003466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039606026003466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T20:32:31Z","timestamp":1789504351000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039606026003466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":32,"alternative-id":["S0039606026003466"],"URL":"https:\/\/doi.org\/10.1016\/j.surg.2026.110421","relation":{},"ISSN":["0039-6060"],"issn-type":[{"value":"0039-6060","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of anastomotic patency and remnant pancreatic function between invagination and duct-to-mucosa pancreaticojejunostomy: A follow-up study of a randomized trial","name":"articletitle","label":"Article Title"},{"value":"Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surg.2026.110421","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110421"}}