{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:20:02Z","timestamp":1792740002522,"version":"4.5.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgical Neurology"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1016\/j.surneu.2007.07.031","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T15:57:31Z","timestamp":1201190251000},"page":"337-343","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats"],"prefix":"10.1016","volume":"70","author":[{"given":"Alper","family":"Karaoglan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Akdemir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seref","family":"Barut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibel","family":"Kokturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafize","family":"Uzun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Tasyurekli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Colak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.surneu.2007.07.031_bib1","first-page":"61","article-title":"Antiplatelet activity of cis-resveratrol","volume":"22","author":"Bertelli","year":"1996","journal-title":"Drugs Exp Clin Res"},{"key":"10.1016\/j.surneu.2007.07.031_bib2","first-page":"1","article-title":"Antiplatelet activity of synthetic and natural resveratrol in red wine","volume":"17","author":"Bertelli","year":"1995","journal-title":"Int J Tissue React"},{"key":"10.1016\/j.surneu.2007.07.031_bib3","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"Microsomal lipid peroxidation","volume":"52","author":"Buege","year":"1978","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.surneu.2007.07.031_bib4","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1097\/00006123-200212000-00002","article-title":"Endothelin receptor antagonists and cerebral vasospasm: an update","volume":"51","author":"Chow","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1016\/j.surneu.2007.07.031_bib5","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1161\/01.STR.16.4.595","article-title":"Subarachnoid haemorrhage in the rat: angiography and fluorescence microscopy of the major cerebral arteries","volume":"16","author":"Delgado","year":"1985","journal-title":"Stroke"},{"key":"10.1016\/j.surneu.2007.07.031_bib6","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/sj.bjp.0702749","article-title":"trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets","volume":"128","author":"Dobrydneva","year":"1999","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.surneu.2007.07.031_bib7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1152\/physrev.1998.78.1.53","article-title":"Regulation of the cerebral circulation: role of endothelium and potassium channels","volume":"78","author":"Faraci","year":"1998","journal-title":"Physiol Rev"},{"key":"10.1016\/j.surneu.2007.07.031_bib8","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1016\/S0024-3205(97)00883-7","article-title":"Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests","volume":"61","author":"Fauconneau","year":"1997","journal-title":"Life Sci"},{"key":"10.1016\/j.surneu.2007.07.031_bib9","first-page":"336","article-title":"Current concepts of pathophysiology and management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage","volume":"3","author":"Findlay","year":"1991","journal-title":"Cerebrovasc Brain Metab Rev"},{"key":"10.1016\/j.surneu.2007.07.031_bib10","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0024-3205(99)00410-5","article-title":"Biological effects of resveratrol","volume":"66","author":"Fremont","year":"2000","journal-title":"Life Sci"},{"key":"10.1016\/j.surneu.2007.07.031_bib11","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3171\/jns.1998.89.5.0748","article-title":"Oxidative stress in the human brain after subarachnoid hemorrhage","volume":"89","author":"Gaetani","year":"1998","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib12","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/00005344-200103000-00004","article-title":"Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys","volume":"37","author":"Giovannini","year":"2001","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.surneu.2007.07.031_bib13","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/sj.bjp.0705688","article-title":"Neuroprotective effects of resveratrol against beta-amyloid\u2013induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C","volume":"141","author":"Han","year":"2004","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.surneu.2007.07.031_bib14","doi-asserted-by":"crossref","unstructured":"Hansen-Schwartz J, Hoel NL, Zhou M, et al. Subarachnoid hemorrhage enhances endothelin receptor expression and function in rat cerebral arteries. Neurosurgery 2003;52:1188-94, 1194-5.","DOI":"10.1227\/01.NEU.0000058467.82442.64"},{"key":"10.1016\/j.surneu.2007.07.031_bib15","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0024-3205(01)01195-X","article-title":"Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia","volume":"69","author":"Huang","year":"2001","journal-title":"Life Sci"},{"key":"10.1016\/j.surneu.2007.07.031_bib16","first-page":"207","article-title":"Relaxant effect of trans-resveratrol on isolated porcine coronary arteries","volume":"49","author":"Jager","year":"1999","journal-title":"Arzneimittelforschung"},{"key":"10.1016\/j.surneu.2007.07.031_bib17","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1161\/01.STR.30.4.867","article-title":"Amelioration of vasospasm after subarachnoid hemorrhage in transgenic mice overexpressing CuZn-superoxide dismutase","volume":"30","author":"Kamii","year":"1999","journal-title":"Stroke"},{"issue":"Suppl 1","key":"10.1016\/j.surneu.2007.07.031_bib18","first-page":"S1:2","article-title":"Endothelin-1 levels in plasma and cerebrospinal fluid of patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage","volume":"64","author":"Kessler","year":"2005","journal-title":"Surg Neurol"},{"key":"10.1016\/j.surneu.2007.07.031_bib19","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0008-6363(99)00397-1","article-title":"Evidence for the stimulatory effect of resveratrol on Ca(2+)-activated K+ current in vascular endothelial cells","volume":"45","author":"Li","year":"2000","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.surneu.2007.07.031_bib20","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.2174\/0929867043364919","article-title":"Endothelin and subarachnoid hemorrhage-induced cerebral vasospasm: pathogenesis and treatment","volume":"11","author":"Lin","year":"2004","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.surneu.2007.07.031_bib21","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1161\/01.HYP.0000103162.76220.51","article-title":"Inhibition of cyclic strain-induced endothelin-1 gene expression by resveratrol","volume":"42","author":"Liu","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.surneu.2007.07.031_bib22","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1017\/S0317167100041949","article-title":"Malondialdehyde, glutathione peroxidase, and superoxide dismutase in cerebrospinal fluid during cerebral vasospasm in monkeys","volume":"19","author":"Macdonald","year":"1992","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.surneu.2007.07.031_bib23","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0891-5849(94)90064-7","article-title":"Cerebral vasospasm and free radicals","volume":"16","author":"Macdonald","year":"1994","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.surneu.2007.07.031_bib24","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1124\/jpet.102.033340","article-title":"Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model","volume":"302","author":"Marier","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.surneu.2007.07.031_bib25","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1161\/01.STR.0000027207.67639.1E","article-title":"Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase","volume":"33","author":"McGirt","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.surneu.2007.07.031_bib26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1254\/jphs.FP0050863","article-title":"The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery","volume":"101","author":"Novakovic","year":"2006","journal-title":"J Pharmacol Sci"},{"key":"10.1016\/j.surneu.2007.07.031_bib27","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1161\/01.STR.24.10.1541","article-title":"Impairment of anti-platelet-aggregating activity of endothelial cells after experimental subarachnoid hemorrhage","volume":"24","author":"Ohkuma","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.surneu.2007.07.031_bib28","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1021\/np970069t","article-title":"Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-d-glucopyranoside and related compounds","volume":"60","author":"Orsini","year":"1997","journal-title":"J Nat Prod"},{"key":"10.1016\/j.surneu.2007.07.031_bib29","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1161\/01.STR.17.2.196","article-title":"Biological defence mechanism in the pathogenesis of prolonged cerebral vasospasm in the patients with ruptured intracranial aneurysms","volume":"17","author":"Sakaki","year":"1986","journal-title":"Stroke"},{"key":"10.1016\/j.surneu.2007.07.031_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/jcbfm.1988.1","article-title":"Free radical reaction and biological defense mechanism in the pathogenesis of prolonged vasospasm in experimental subarachnoid hemorrhage","volume":"8","author":"Sakaki","year":"1988","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.surneu.2007.07.031_bib31","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3171\/jns.1981.54.3.0357","article-title":"The effect of a lipid hydroperoxide of arachidonic acid on the canine basilar artery. An experimental study on cerebral vasospasm","volume":"54","author":"Sasaki","year":"1981","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib32","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3171\/jns.1995.82.1.0055","article-title":"Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. Correlation with cerebral vasospasm, delayed ischemic neurological deficits, and volume of hematoma","volume":"82","author":"Seifert","year":"1995","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib33","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1254\/jjp.88.227","article-title":"Cerebrovascular inflammation following subarachnoid hemorrhage","volume":"88","author":"Sercombe","year":"2002","journal-title":"Jpn J Pharmacol"},{"key":"10.1016\/j.surneu.2007.07.031_bib34","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1016\/S0024-3205(02)02083-0","article-title":"Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats","volume":"71","author":"Sharma","year":"2002","journal-title":"Life Sci"},{"key":"10.1016\/j.surneu.2007.07.031_bib35","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1161\/01.STR.25.4.864","article-title":"The role of superoxide anions in the pathogenesis of cerebral vasospasm","volume":"25","author":"Shishido","year":"1994","journal-title":"Stroke"},{"key":"10.1016\/j.surneu.2007.07.031_bib36","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/clinchem\/34.3.497","article-title":"A simple method for clinical assay of superoxide dismutase","volume":"34","author":"Sun","year":"1988","journal-title":"Clin Chem"},{"key":"10.1016\/j.surneu.2007.07.031_bib37","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3171\/jns.1992.77.1.0096","article-title":"The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage","volume":"77","author":"Suzuki","year":"1992","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib38","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/10715760000300661","article-title":"Resveratrol inhibition of lipid peroxidation","volume":"33","author":"Tadolini","year":"2000","journal-title":"Free Radic Res"},{"key":"10.1016\/j.surneu.2007.07.031_bib39","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.3171\/jns.2005.102.6.1101","article-title":"Cerebrovascular characterization of clazosentan, the first nonpeptide endothelin receptor antagonist clinically effective for the treatment of cerebral vasospasm. Part I: inhibitory effect on endothelin (A) receptor-mediated contraction","volume":"102","author":"Vatter","year":"2005","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib40","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.3171\/jns.2005.102.6.1108","article-title":"Cerebrovascular characterization of clazosentan, the first nonpeptide endothelin receptor antagonist shown to be clinically effective for the treatment of cerebral vasospasm. Part II: effect on endothelin (B) receptor-mediated relaxation","volume":"102","author":"Vatter","year":"2005","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib41","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3171\/jns.1982.56.2.0197","article-title":"Intracranial pressure changes following aneurysm rupture. Part 2: associated cerebrospinal fluid lactacidosis","volume":"56","author":"Voldby","year":"1982","journal-title":"J Neurosurg"},{"key":"10.1016\/j.surneu.2007.07.031_bib42","first-page":"703","article-title":"Effects of resveratrol on secondary damages after acute spinal cord injury in rats","volume":"24","author":"Yang","year":"2003","journal-title":"Acta Pharmacol Sin"},{"key":"10.1016\/j.surneu.2007.07.031_bib43","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s00701-002-1000-z","article-title":"Effect of endothelin-converting enzyme inhibitors on big endothelin-1 induced contraction in isolated rat basilar artery","volume":"144","author":"Zimmermann","year":"2002","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.surneu.2007.07.031_bib44","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1097\/00006123-199810000-00083","article-title":"Endothelin and subarachnoid hemorrhage: an overview","volume":"43","author":"Zimmermann","year":"1998","journal-title":"Neurosurgery"}],"container-title":["Surgical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090301907008282?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090301907008282?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:23:55Z","timestamp":1758763435000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090301907008282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["S0090301907008282"],"URL":"https:\/\/doi.org\/10.1016\/j.surneu.2007.07.031","relation":{},"ISSN":["0090-3019"],"issn-type":[{"value":"0090-3019","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats","name":"articletitle","label":"Article Title"},{"value":"Surgical Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.surneu.2007.07.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}