{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T20:38:13Z","timestamp":1776112693485,"version":"3.50.1"},"reference-count":11,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surveyophthalmol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Survey of Ophthalmology"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.survophthal.2015.06.002","type":"journal-article","created":{"date-parts":[[2015,6,14]],"date-time":"2015-06-14T13:14:51Z","timestamp":1434287691000},"page":"596-599","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Second chances"],"prefix":"10.1016","volume":"60","author":[{"given":"Lina","family":"Nagia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer I.","family":"Doyle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James R.","family":"Hackney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Vaphiades","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanning B.","family":"Kline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc H.","family":"Levin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.survophthal.2015.06.002_bib1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1750-3639.2009.00352.x","article-title":"Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors","volume":"20","author":"Capper","year":"2010","journal-title":"Brain Pathol"},{"issue":"6","key":"10.1016\/j.survophthal.2015.06.002_bib2","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.2353\/ajpath.2010.100680","article-title":"Molecular classification of low-grade diffuse gliomas","volume":"177","author":"Kim","year":"2010","journal-title":"Am J Pathol"},{"issue":"2","key":"10.1016\/j.survophthal.2015.06.002_bib3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00401-007-0243-4","article-title":"The 2007 WHO classification of tumours of the central nervous system","volume":"114","author":"Louis","year":"2007","journal-title":"Acta Neuropathol"},{"issue":"2","key":"10.1016\/j.survophthal.2015.06.002_bib4","first-page":"228","article-title":"p53 protein alterations in adult astrocytic tumors and oligodendrogliomas","volume":"52","author":"Nayak","year":"2004","journal-title":"Neurol India"},{"issue":"1","key":"10.1016\/j.survophthal.2015.06.002_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clineuro.2012.07.002","article-title":"Current treatment of low grade astrocytoma: a review","volume":"115","author":"Pedersen","year":"2013","journal-title":"Clin Neurol Neurosurg"},{"issue":"3","key":"10.1016\/j.survophthal.2015.06.002_bib6","first-page":"155","article-title":"Malignant optic glioma in an adult: initial CT abnormality limited to the posterior orbit, leptomeningeal seeding of the tumor","volume":"65","author":"Shapiro","year":"1982","journal-title":"Minn Med"},{"issue":"12","key":"10.1016\/j.survophthal.2015.06.002_bib7","first-page":"1036","article-title":"Chemotherapy for treatment of grade II gliomas","volume":"28","author":"Strowd","year":"2014","journal-title":"Oncology (Williston Park)"},{"issue":"4","key":"10.1016\/j.survophthal.2015.06.002_bib8","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s11864-014-0304-6","article-title":"Therapeutic decision making in patients with newly diagnosed low grade glioma","volume":"15","author":"Tandon","year":"2014","journal-title":"Curr Treat Options Oncol"},{"issue":"12","key":"10.1016\/j.survophthal.2015.06.002_bib9","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1016\/j.clineuro.2013.10.010","article-title":"Clinical outcome of surgically treated low-grade gliomas: a retrospective analysis of a single institute","volume":"115","author":"Turkoglu","year":"2013","journal-title":"Clin Neurol Neurosurg"},{"issue":"3","key":"10.1016\/j.survophthal.2015.06.002_bib10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s12254-012-0014-3","article-title":"Current treatment of low grade gliomas","volume":"5","author":"Van den Bent","year":"2012","journal-title":"Memo"},{"issue":"7","key":"10.1016\/j.survophthal.2015.06.002_bib11","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1001\/archopht.1989.01070020075033","article-title":"Orbital optic nerve glioma in adult life","volume":"107","author":"Wulc","year":"1989","journal-title":"Arch Ophthalmol"}],"container-title":["Survey of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039625715001095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039625715001095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T11:43:17Z","timestamp":1758541397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039625715001095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["S0039625715001095"],"URL":"https:\/\/doi.org\/10.1016\/j.survophthal.2015.06.002","relation":{},"ISSN":["0039-6257"],"issn-type":[{"value":"0039-6257","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Second chances","name":"articletitle","label":"Article Title"},{"value":"Survey of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.survophthal.2015.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}