{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T11:14:24Z","timestamp":1768821264778,"version":"3.49.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surveyophthalmol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Survey of Ophthalmology"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.survophthal.2018.10.003","type":"journal-article","created":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T20:59:05Z","timestamp":1539377945000},"page":"225-232","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Primary vitreoretinal natural killer\/T-cell lymphoma with breast involvement: A case report and review of the literature"],"prefix":"10.1016","volume":"64","author":[{"given":"Shuang","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6046-7556","authenticated-orcid":false,"given":"Yingming","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolong","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongjing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yisheng","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.survophthal.2018.10.003_bib1","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1001\/jamaophthalmol.2017.3286","article-title":"Association of disease location and treatment with survival in diffuse large B-cell lymphoma of the eye and ocular adnexal region","volume":"135","author":"Ahmed","year":"2017","journal-title":"JAMA Ophthalmol"},{"issue":"3","key":"10.1016\/j.survophthal.2018.10.003_bib2","first-page":"283","article-title":"Primary vitreoretinal lymphoma -- a review","volume":"6","author":"Araujo","year":"2017","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1182\/blood-2003-12-4197","article-title":"Quantification of circulating Epstein-Barr virus (EBV) DNA in the diagnosis and monitoring of natural killer cell and EBV-positive lymphomas in immunocompetent patients","volume":"104","author":"Au","year":"2004","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib4","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1182\/blood-2015-01-620518","article-title":"High frequency of MYD88 mutations in vitreoretinal B-cell lymphoma: a valuable tool to improve diagnostic yield of vitreous aspirates","volume":"126","author":"Bonzheim","year":"2015","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.survophthal.2018.10.003_bib5","doi-asserted-by":"crossref","first-page":"7989","DOI":"10.18632\/oncotarget.14008","article-title":"Next generation sequencing of vitreoretinal lymphoma from small volume intraocular liquid biopsies: new routes to targeted therapies","volume":"8","author":"Cani","year":"2017","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.survophthal.2018.10.003_bib6","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0161-6420(00)00401-2","article-title":"Interleukin-10 and intraocular-central nervous system lymphoma","volume":"108","author":"Cassoux","year":"2001","journal-title":"Ophthalmology"},{"issue":"7","key":"10.1016\/j.survophthal.2018.10.003_bib7","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1167\/iovs.06-0031","article-title":"IL-10 measurement in aqueous humor for screening patients with suspicion of primary intraocular lymphoma","volume":"48","author":"Cassoux","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"11","key":"10.1016\/j.survophthal.2018.10.003_bib8","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1634\/theoncologist.2011-0210","article-title":"Primary vitreoretinal lymphoma: a report from an international primary central nervous system lymphoma collaborative group symposium","volume":"16","author":"Chan","year":"2011","journal-title":"Oncologist"},{"issue":"8","key":"10.1016\/j.survophthal.2018.10.003_bib9","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/RLU.0b013e3181e4dcbf","article-title":"Metabolic activity measured by F-18 FDG PET in natural killer-cell lymphoma compared to aggressive B- and T-cell lymphomas","volume":"35","author":"Chan","year":"2010","journal-title":"Clin Nucl Med"},{"issue":"8","key":"10.1016\/j.survophthal.2018.10.003_bib10","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/0002-9394(51)90691-5","article-title":"Malignant lymphoma of the uveal tract","volume":"34","author":"Cooper","year":"1951","journal-title":"Am J Ophthalmol"},{"issue":"7","key":"10.1016\/j.survophthal.2018.10.003_bib11","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/j.ophtha.2016.01.037","article-title":"ISOLD: a new highly sensitive interleukin score for intraocular lymphoma diagnosis","volume":"123","author":"Costopoulos","year":"2016","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.survophthal.2018.10.003_bib12","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s00417-004-0890-2","article-title":"Primary intraocular lymphoma of T-cell type: report of a case and review of the literature","volume":"243","author":"Coupland","year":"2005","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"4","key":"10.1016\/j.survophthal.2018.10.003_bib13","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1080\/09273940903168696","article-title":"Pathophysiology of retinal lymphoma","volume":"17","author":"Coupland","year":"2009","journal-title":"Ocul Immunol Inflamm"},{"issue":"6","key":"10.1016\/j.survophthal.2018.10.003_bib14","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1442-9071.2008.01843.x","article-title":"Understanding intraocular lymphomas","volume":"36","author":"Coupland","year":"2008","journal-title":"Clin Exp Ophthalmol"},{"issue":"11","key":"10.1016\/j.survophthal.2018.10.003_bib15","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1016\/S0161-6420(99)90492-X","article-title":"T-cell and t\/natural killer-cell lymphomas involving ocular and ocular adnexal tissues: a clinicopathologic, immunohistochemical, and molecular study of seven cases","volume":"106","author":"Coupland","year":"1999","journal-title":"Ophthalmology"},{"issue":"7","key":"10.1016\/j.survophthal.2018.10.003_bib16","first-page":"977","article-title":"Who is who in primary vitreoretinal lymphoma?","volume":"1","author":"Ferreri","year":"2015","journal-title":"JAMA Ophthalmol"},{"issue":"2","key":"10.1016\/j.survophthal.2018.10.003_bib17","doi-asserted-by":"crossref","first-page":"e52385","DOI":"10.1371\/journal.pone.0052385","article-title":"Cytokine profile in human eyes: contribution of a new cytokine combination for differential diagnosis between intraocular lymphoma or uveitis","volume":"8","author":"Fisson","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.survophthal.2018.10.003_bib18","first-page":"e783","article-title":"High-definition optical coherence tomography features of primary vitreoretinal lymphoma","volume":"42","author":"Forooghian","year":"2011","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"10.1016\/j.survophthal.2018.10.003_bib19","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/modpathol.2016.47","article-title":"Nasal-type NK-T-cell lymphomas are more frequently T rather than NK lineage based on T-cell receptor gene, RNA, and protein studies: lineage does not predict clinical behavior","volume":"29","author":"Hong","year":"2016","journal-title":"Mod Pathol"},{"issue":"16","key":"10.1016\/j.survophthal.2018.10.003_bib20","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1182\/blood-2015-09-672030","article-title":"The clinical significance of EBV DNA in the plasma and peripheral blood mononuclear cells of patients with or without EBV diseases","volume":"127","author":"Kanakry","year":"2016","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.survophthal.2018.10.003_bib21","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1097\/ICO.0000000000000420","article-title":"Conjunctival extranodal natural killer\/t-cell lymphoma, nasal type","volume":"34","author":"Kiratli","year":"2015","journal-title":"Cornea"},{"issue":"11","key":"10.1016\/j.survophthal.2018.10.003_bib22","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1136\/bjophthalmol-2017-311574","article-title":"Combined treatment of primary vitreoretinal lymphomas significantly prolongs the time to first relapse","volume":"102","author":"Klimova","year":"2018","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib23","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0002-9394(75)90453-5","article-title":"Ocular reticulum cell sarcoma","volume":"79","author":"Klingele","year":"1975","journal-title":"Am J Ophthalmol"},{"issue":"8","key":"10.1016\/j.survophthal.2018.10.003_bib24","first-page":"e680","article-title":"Correlation between measurement of IL-10 and IL-6 in paired aqueous humour and vitreous fluid in primary vitreoretinal lymphoma","volume":"93","author":"Kuiper","year":"2016","journal-title":"Acta Ophthalmologica"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib25","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1001\/jamaophthalmol.2013.569","article-title":"Vitreoretinal lymphoma: a 20-year review of incidence, clinical and cytologic features, treatment, and outcomes","volume":"131","author":"Levasseur","year":"2013","journal-title":"JAMA Ophthalmol"},{"issue":"3","key":"10.1016\/j.survophthal.2018.10.003_bib26","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.survophthal.2008.02.004","article-title":"Ophthalmic manifestations, cytology immunohistochemistry, and molecular analysis of intraocular metastatic t-cell lymphoma: report of a case and review of the literature","volume":"53","author":"Levy-Clarke","year":"2008","journal-title":"Surv Ophthalmol"},{"issue":"9","key":"10.1016\/j.survophthal.2018.10.003_bib27","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1007\/s00417-011-1669-x","article-title":"Subretinal lymphomatous infiltration in primary intraocular lymphoma revealed by optical coherence tomography","volume":"249","author":"Liang","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib28","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s12886-015-0158-0","article-title":"First case of primary intraocular natural killer T-cell lymphoma","volume":"15","author":"Maruyama","year":"2015","journal-title":"BMC Ophthalmol"},{"issue":"6","key":"10.1016\/j.survophthal.2018.10.003_bib29","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.ajo.2015.08.033","article-title":"The role of chorioretinal biopsy in the diagnosis of intraocular lymphoma","volume":"160","author":"Mastropasqua","year":"2015","journal-title":"Am J Ophthalmol"},{"issue":"Suppl 1","key":"10.1016\/j.survophthal.2018.10.003_bib30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/ijlh.12817","article-title":"The 2017 WHO update on mature T- and natural killer (NK) cell neoplasms","volume":"40","author":"Matutes","year":"2018","journal-title":"Int J Lab Hematol"},{"issue":"5","key":"10.1016\/j.survophthal.2018.10.003_bib31","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.ophtha.2012.11.007","article-title":"Multicolor flowcytometric immunophenotyping is a valuable tool for detection of intraocular lymphoma","volume":"120","author":"Missotten","year":"2013","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.survophthal.2018.10.003_bib32","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.ajo.2014.08.031","article-title":"Paraneoplastic cloudy vitelliform submaculopathy in primary vitreoretinal lymphoma","volume":"158","author":"Pang","year":"2014","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.survophthal.2018.10.003_bib33","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1001\/jamaophthalmol.2014.4755","article-title":"Treatment Strategies in Primary Vitreoretinal Lymphoma A 17-Center European Collaborative Study","volume":"133","author":"Riemens","year":"2015","journal-title":"JAMA Ophthalmol"},{"issue":"5","key":"10.1016\/j.survophthal.2018.10.003_bib34","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.survophthal.2013.12.001","article-title":"Primary intraocular lymphoma","volume":"59","author":"Sagoo","year":"2014","journal-title":"Surv Ophthalmol"},{"issue":"12","key":"10.1016\/j.survophthal.2018.10.003_bib35","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s00417-016-3395-x","article-title":"Optical coherence tomography manifestations of primary vitreoretinal lymphoma","volume":"254","author":"Saito","year":"2016","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"5","key":"10.1016\/j.survophthal.2018.10.003_bib36","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00417-011-1718-5","article-title":"Repeated IL-10 measurement in aqueous humor and OCT imaging are valuable tools to monitor intraocular lymphoma treated with intravitreal injections of methotrexate","volume":"250","author":"Saleh","year":"2012","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"4","key":"10.1016\/j.survophthal.2018.10.003_bib37","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.humpath.2012.02.007","article-title":"The spectrum of lymphoblastic, nodal and extranodal T-cell lymphomas: characteristic features and diagnostic dilemmas","volume":"44","author":"Savage","year":"2013","journal-title":"Hum Pathol"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib38","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/112067210601600132","article-title":"Epstein-Barr positive T-cell lymphoma in the ocular region","volume":"16","author":"Sj\u00f6","year":"2006","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.survophthal.2018.10.003_bib39","series-title":"WHO classification of tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow","year":"2008"},{"issue":"20","key":"10.1016\/j.survophthal.2018.10.003_bib40","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1182\/blood-2016-01-643569","article-title":"The 2016 revision of the World Health Organization classification of lymphoid neoplasms","volume":"127","author":"Swerdlow","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.survophthal.2018.10.003_bib41","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.humpath.2017.12.006","article-title":"Identification of T-cell receptor expression in EBV-positive neoplastic cells in extranodal NK\/T-cell lymphoma, nasal-type, and comparison with T-cell receptor gene rearrangement by Biomed-2 assay","volume":"73","author":"Takayama","year":"2018","journal-title":"Hum Pathol"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib42","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s13045-017-0452-9","article-title":"The diagnosis and management of NK\/T-cell lymphomas","volume":"10","author":"Tse","year":"2017","journal-title":"J\u00a0Hematol Oncol"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib43","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/hon.2459","article-title":"Epstein Barr virus negative extranodal \u201ctrue\u201d natural killer cell lymphoma harbouring a KDM6A mutation","volume":"36","author":"Tsuyama","year":"2018","journal-title":"Hematol Oncol"},{"issue":"3","key":"10.1016\/j.survophthal.2018.10.003_bib44","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.ajo.2013.12.014","article-title":"Distinct microRNA-155 expression in the vitreous of patients with primary vitreoretinal lymphoma and uveitis","volume":"157","author":"Tuo","year":"2014","journal-title":"Am J Ophthalmol"},{"issue":"9","key":"10.1016\/j.survophthal.2018.10.003_bib45","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/S0161-6420(93)31469-7","article-title":"Intraocular lymphoma: clinical and histopathologic diagnosis","volume":"100","author":"Whitcup","year":"1993","journal-title":"Ophthalmology"},{"issue":"8","key":"10.1016\/j.survophthal.2018.10.003_bib46","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/S0161-6420(03)00811-X","article-title":"Vitreous cytokine levels","volume":"110","author":"Wolf","year":"2003","journal-title":"Ophthalmology"},{"issue":"1","key":"10.1016\/j.survophthal.2018.10.003_bib47","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12886-017-0494-3","article-title":"Ocular manifestations as first signs of systemic T cell lymphoma in two cases","volume":"17","author":"Zhang","year":"2017","journal-title":"BMC Ophthalmol"}],"container-title":["Survey of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039625718300547?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0039625718300547?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T11:45:53Z","timestamp":1758541553000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0039625718300547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S0039625718300547"],"URL":"https:\/\/doi.org\/10.1016\/j.survophthal.2018.10.003","relation":{},"ISSN":["0039-6257"],"issn-type":[{"value":"0039-6257","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary vitreoretinal natural killer\/T-cell lymphoma with breast involvement: A case report and review of the literature","name":"articletitle","label":"Article Title"},{"value":"Survey of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.survophthal.2018.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}