{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:36:06Z","timestamp":1793115366457,"version":"4.5.0"},"reference-count":66,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T00:00:00Z","timestamp":1681344000000},"content-version":"vor","delay-in-days":1231,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T00:00:00Z","timestamp":1574985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T00:00:00Z","timestamp":1571961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Elen"},{"DOI":"10.13039\/501100014382","name":"Ipsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Endoceutics"},{"name":"SST"},{"name":"Gynecologic Cancers Research Foundation"},{"name":"Cellular Medicine Association"},{"name":"Elen"},{"DOI":"10.13039\/501100014382","name":"Ipsen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Endoceutics"},{"DOI":"10.13039\/100014707","name":"SST","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014707","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Gynecologic Cancers Research Foundation"},{"name":"The Cellular Medicine Association"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Cervical cancer is the leading cause of cancer deaths in women in the developing world. New technologies have been developed to allow for more rapid, cost-effective, and sensitive cervical cancer screening and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this study was to describe methods for detection and treatment of human papillomavirus (HPV), cervical dysplasia (CD), and cervical cancer. New technologies and updated screening strategies will be emphasized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature search was conducted using PubMed to identify publications relevant to the subject.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure<\/jats:title>\n                    <jats:p>Sensitivity and cost-effectiveness of new cervical cancer screening methods were the main outcome measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>HPV and cervical cancer have a significant global impact. Research and innovations related to detection and treatment are key in reducing their burden worldwide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Screening a woman for HPV and CD can dramatically decrease her risk of dying from cervical cancer. New, rapid, low-cost, HPV testing can allow for high-volume screening for the approximately 1.5 billion women who have never been screened. HPV screening can then be combined with high resolution digital colposcopy to detect CD. In the near future, these colposcopic images will be interpreted by artificial intelligence software. Detected lesions can then be treated easily and effectively with thermocoagulation. This see-and-treat model is a sensitive, efficient, and low-cost vision for the future.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.sxmr.2019.09.005","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T05:21:04Z","timestamp":1575264064000},"page":"28-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":424,"title":["Cervical Cancer Screening: Past, Present, and Future"],"prefix":"10.1093","volume":"8","author":[{"given":"Sarah L.","family":"Bedell","sequence":"first","affiliation":[{"name":"The Center for Vulvovaginal Disorders , New York , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena S.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Yale University , New Haven , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia R.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Duke University , Durham , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew T.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"The Center for Vulvovaginal Disorders , New York , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,11,29]]},"reference":[{"key":"2023041308060597800_","article-title":"Cancer, Key Statics","author":"World Health Organization"},{"key":"2023041308060597800_","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F","article-title":"Human papillomavirus is a necessary cause of invasive cervical cancer worldwide","volume":"189","author":"Walboomers","year":"1999","journal-title":"J Pathol"},{"key":"2023041308060597800_","article-title":"HPV and cancer 2019","author":"National Cancer Institute"},{"key":"2023041308060597800_","first-page":"e111","article-title":"Practice bulletin no. 168: Cervical cancer screening and prevention","volume":"128","author":"Committee on Practice Bulletins\u2013Gynecology","year":"2016","journal-title":"Obstet Gynecol"},{"key":"2023041308060597800_","first-page":"441","article-title":"Cervical cancer screening","volume":"97","author":"Rerucha","year":"2018","journal-title":"Am Fam Physician"},{"key":"2023041308060597800_","article-title":"2015 Sexually transmitted diseases treatment guidelines: Human papillomavirus (HPV) infection","author":"Centers for Disease Control and Prevention"},{"key":"2023041308060597800_","article-title":"Cervical cancer","volume":"2011","author":"Martin-Hirsch","year":"2011","journal-title":"BMJ Clin Evid"},{"key":"2023041308060597800_","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1093\/jnci\/djn044","article-title":"Rapid clearance of human papillomavirus and implications for clinical focus on persistent infections","volume":"100","author":"Rodr\u00edguez","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"2023041308060597800_","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1086\/516784","article-title":"A 2-year prospective study of human papillomavirus persistence among women with a cytological diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion","volume":"195","author":"Plummer","year":"2007","journal-title":"J Infect Dis"},{"key":"2023041308060597800_","article-title":"IARC Working Group on the Evaluation of Carcinogenic Risk to Humans. 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