{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T19:45:24Z","timestamp":1784058324707,"version":"3.55.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sexual Medicine Reviews"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.sxmr.2020.06.004","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T02:24:25Z","timestamp":1596594265000},"page":"628-635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Does Lowering Hemoglobin A1c Reduce Penile Prosthesis Infection: A Systematic Review"],"prefix":"10.1093","volume":"9","author":[{"given":"Brian P.","family":"Dick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayad","family":"Yousif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Raheem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne J.G.","family":"Hellstrom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"10.1016\/j.sxmr.2020.06.004_bib1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/ijir.2016.38","article-title":"Erectile dysfunction in young men with type 1 diabetes","volume":"29","author":"Maiorino","year":"2017","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.sxmr.2020.06.004_bib2","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1111\/dme.13403","article-title":"High prevalence of erectile dysfunction in diabetes: a systematic review and meta-analysis of 145 studies","volume":"34","author":"Kouidrat","year":"2017","journal-title":"Diabet Med"},{"key":"10.1016\/j.sxmr.2020.06.004_bib3","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/17434440.2019.1598259","article-title":"An update on: long-term outcomes of penile prostheses for the treatment of erectile dysfunction","volume":"16","author":"Dick","year":"2019","journal-title":"Expert Rev Med Devices"},{"key":"10.1016\/j.sxmr.2020.06.004_bib4","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1089\/sur.2015.164","article-title":"Infection of penile prostheses in patients with diabetes mellitus","volume":"17","author":"Christodoulidou","year":"2016","journal-title":"Surg Infect (Larchmt)"},{"key":"10.1016\/j.sxmr.2020.06.004_bib5","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1086\/427690","article-title":"Serious infections in elderly patients with diabetes mellitus","volume":"40","author":"Rajagopalan","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.sxmr.2020.06.004_bib6","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.sxmr.2019.05.003","article-title":"Etiology of erectile dysfunction and duration of symptoms in patients undergoing penile prosthesis: a systematic review","volume":"8","author":"Bajic","year":"2020","journal-title":"Sex Med Rev"},{"key":"10.1016\/j.sxmr.2020.06.004_bib7","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1056\/NEJMoa0806470","article-title":"10-Year follow-up of intensive glucose control in type 2 diabetes","volume":"359","author":"Holman","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.sxmr.2020.06.004_bib8","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1056\/NEJMoa052187","article-title":"Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes","volume":"353","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.sxmr.2020.06.004_bib9","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1056\/NEJMoa0802987","article-title":"Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes","volume":"358","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.sxmr.2020.06.004_bib10","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1056\/NEJMoa0802743","article-title":"Effects of intensive glucose lowering in type 2 diabetes","volume":"358","year":"2008","journal-title":"N\u00a0Engl J Med"},{"issue":"Supplement_1","key":"10.1016\/j.sxmr.2020.06.004_bib11","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.2337\/dc13-S011","article-title":"Standards of medical care in diabetes--2013","volume":"36","year":"2013","journal-title":"Diabetes Care"},{"issue":"Supplement 1","key":"10.1016\/j.sxmr.2020.06.004_bib12","doi-asserted-by":"crossref","first-page":"S144","DOI":"10.2337\/dc18-S014","article-title":"14. Diabetes care in the hospital: standards of medical care in diabetes\u20142018","volume":"41","year":"2018","journal-title":"Diabetes Care"},{"key":"10.1016\/j.sxmr.2020.06.004_bib13","first-page":"386","article-title":"Use of glycosylated hemoglobin to identify diabetics at high risk for penile periprosthetic infections","volume":"147","author":"Bishop","year":"1992","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.sxmr.2020.06.004_bib14","first-page":"1537","article-title":"Quantifying risk of penile prosthesis infection with elevated glycosylated hemoglobin","volume":"159","author":"Wilson","year":"1998","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.sxmr.2020.06.004_bib15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/13685538.2017.1292499","article-title":"Association of the modified frailty index with adverse outcomes after penile prosthesis implantation","volume":"20","author":"Madbouly","year":"2017","journal-title":"Aging Male"},{"key":"10.1016\/j.sxmr.2020.06.004_bib16","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/bju.14076","article-title":"Defining a glycated haemoglobin (HbA1c) level that predicts increased risk of penile implant infection","volume":"121","author":"Habous","year":"2018","journal-title":"BJU Int"},{"key":"10.1016\/j.sxmr.2020.06.004_bib17","first-page":"1","article-title":"Is Hba1c level of diabetic patients associated with penile prosthesis implantation infections?","author":"Canguven","year":"2018","journal-title":"Aging Male"},{"key":"10.1016\/j.sxmr.2020.06.004_bib18","article-title":"Immediate preoperative blood glucose and hemoglobin a1c levels are not predictive of postoperative infections in diabetic men undergoing penile prosthesis placement","author":"Osman","year":"2020","journal-title":"Int J Impot Res"},{"issue":"Supplement 1","key":"10.1016\/j.sxmr.2020.06.004_bib19","doi-asserted-by":"crossref","first-page":"S66","DOI":"10.2337\/dc20-S006","article-title":"6. Glycemic targets: standards of medical care in diabetes\u20142020","volume":"43","year":"2020","journal-title":"Diabetes Care"},{"key":"10.1016\/j.sxmr.2020.06.004_bib20","first-page":"2182","article-title":"Long-term revision rate due to infection in hydrophilic-coated inflatable penile prostheses: 11-year follow-up","volume":"9","author":"Serefoglu","year":"2012","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.sxmr.2020.06.004_bib21","first-page":"614","article-title":"Long-term infection outcomes after original antibiotic impregnated inflatable penile prosthesis implants: up to 7.7 years of followup","volume":"185","author":"Carson","year":"2011","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.sxmr.2020.06.004_bib22","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.eururo.2011.01.046","article-title":"Long-term infection rates in diabetic patients implanted with antibiotic-impregnated versus nonimpregnated inflatable penile prostheses: 7-year outcomes","volume":"60","author":"Mulcahy","year":"2011","journal-title":"Eur Urol"},{"key":"10.1016\/j.sxmr.2020.06.004_bib23","first-page":"223","article-title":"Impact of surgeon case volume on reoperation rates after inflatable penile prosthesis surgery","volume":"197","author":"Onyeji","year":"2017","journal-title":"J\u00a0Urol"},{"issue":"Supplement 1","key":"10.1016\/j.sxmr.2020.06.004_bib24","first-page":"S33","article-title":"6. Glycemic targets","volume":"38","year":"2015","journal-title":"Diabetes Care"},{"issue":"Suppl 5","key":"10.1016\/j.sxmr.2020.06.004_bib25","doi-asserted-by":"crossref","first-page":"S860","DOI":"10.21037\/tau.2017.05.28","article-title":"Penile implants: a look into the future","volume":"6","author":"Rodriguez","year":"2017","journal-title":"Transl Androl Urol"},{"key":"10.1016\/j.sxmr.2020.06.004_bib26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.artd.2017.02.002","article-title":"The American Joint Replacement Registry-the first 5 years","volume":"3","author":"Etkin","year":"2017","journal-title":"Arthroplast Today"},{"issue":"Supplement","key":"10.1016\/j.sxmr.2020.06.004_bib27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.arth.2013.09.028","article-title":"Mitigation and education","volume":"29","author":"Aggarwal","year":"2014","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.sxmr.2020.06.004_bib28","doi-asserted-by":"crossref","first-page":"e8805","DOI":"10.1097\/MD.0000000000008805","article-title":"Is hemoglobin A1c and perioperative hyperglycemia predictive of periprosthetic joint infection following total joint arthroplasty?: a systematic review and meta-analysis","volume":"96","author":"Yang","year":"2017","journal-title":"Medicine"},{"key":"10.1016\/j.sxmr.2020.06.004_bib29","doi-asserted-by":"crossref","first-page":"S263","DOI":"10.1016\/j.arth.2017.04.065","article-title":"Determining the threshold for HbA1c as a predictor for adverse outcomes after total joint arthroplasty: a multicenter, retrospective study","volume":"32","author":"Tarabichi","year":"2017","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.sxmr.2020.06.004_bib30","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.2741\/2757","article-title":"Diabetic complications and dysregulated innate immunity","volume":"13","author":"Graves","year":"2008","journal-title":"Front Biosci"},{"key":"10.1016\/j.sxmr.2020.06.004_bib31","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1161\/CIRCRESAHA.110.217117","article-title":"Activation of protein kinase C isoforms and its impact on diabetic complications","volume":"106","author":"Geraldes","year":"2010","journal-title":"Circ Res"},{"issue":"Suppl 1","key":"10.1016\/j.sxmr.2020.06.004_bib32","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.2119\/molmed.2015.00067","article-title":"Advanced glycation end products: a molecular target for vascular complications in diabetes","volume":"21 Suppl 1","author":"Yamagishi","year":"2015","journal-title":"Mol Med"},{"key":"10.1016\/j.sxmr.2020.06.004_bib33","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0140-6736(96)91141-1","article-title":"Long-term assessment of glucose control by haemoglobin-AGE measurement","volume":"347","author":"Wolffenbuttel","year":"1996","journal-title":"Lancet"}],"container-title":["Sexual Medicine Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2050052120300688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2050052120300688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T19:38:07Z","timestamp":1672774687000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2050052120300688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S2050052120300688"],"URL":"https:\/\/doi.org\/10.1016\/j.sxmr.2020.06.004","relation":{},"ISSN":["2050-0521"],"issn-type":[{"value":"2050-0521","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does Lowering Hemoglobin A1c Reduce Penile Prosthesis Infection: A Systematic Review","name":"articletitle","label":"Article Title"},{"value":"Sexual Medicine Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sxmr.2020.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}