{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:17:50Z","timestamp":1792185470057,"version":"4.4.0"},"reference-count":104,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1016\/j.taap.2003.08.019","type":"journal-article","created":{"date-parts":[[2003,12,11]],"date-time":"2003-12-11T12:47:40Z","timestamp":1071146860000},"page":"298-308","source":"Crossref","is-referenced-by-count":1093,"title":["Toxic effects of ultraviolet radiation on the skin"],"prefix":"10.1016","volume":"195","author":[{"given":"Yasuhiro","family":"Matsumura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honnavara N","family":"Ananthaswamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2003.08.019_BIB1","first-page":"255","article-title":"Ultraviolet light as a carcinogen","volume":"vol. 12","author":"Ananthaswamy","year":"1997"},{"key":"10.1016\/j.taap.2003.08.019_BIB2","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1084\/jem.170.4.1117","article-title":"Identification of the molecular target for the suppression of contact hypersensitivity by UV radiation","volume":"170","author":"Applegate","year":"1989","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2003.08.019_BIB3","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1083\/jcb.140.1.171","article-title":"Ultraviolet light induces apoptosis via direct activation of CD95 (Fas\/APO-1) independently of its ligand CD95L","volume":"40","author":"Aragane","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.taap.2003.08.019_BIB4","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1146\/annurev.bi.56.070187.004023","article-title":"Ras genes","volume":"56","author":"Barbacid","year":"1987","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.taap.2003.08.019_BIB5","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S1046-2023(02)00217-7","article-title":"Role of immunomodulation in diseases responsive to phototherapy","volume":"28","author":"Beissert","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.taap.2003.08.019_BIB6","first-page":"4682","article-title":"Ras oncogenes in human cancer: review","volume":"49","author":"Bos","year":"1989","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB7","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1021\/bi00408a052","article-title":"Sequence specificity in photoreaction of various psoralen derivatives with DNA: role in biological activity","volume":"27","author":"Boyer","year":"1988","journal-title":"Biochemistry"},{"key":"10.1016\/j.taap.2003.08.019_BIB8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1365-2133.1991.tb03281.x","article-title":"High single-dose European PUVA regimen also causes an excess of non-melanoma skin cancer","volume":"124","author":"Bruynzeel","year":"1991","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB9","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1126\/science.1439824","article-title":"Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22","volume":"258","author":"Cannon-Albright","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.taap.2003.08.019_BIB10","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1126\/science.7521539","article-title":"Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1","volume":"265","author":"Dameron","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.taap.2003.08.019_BIB11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0923-1811(98)00065-6","article-title":"PUVA therapy: current concerns in Japan","volume":"19","author":"Danno","year":"1999","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.taap.2003.08.019_BIB12","first-page":"651","article-title":"A preliminary clinical report on the treatment of leukodermia with ammi majus linn","volume":"8","author":"El Mofty","year":"1948","journal-title":"R. Med. Assoc."},{"key":"10.1016\/j.taap.2003.08.019_BIB13","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1002\/(SICI)1097-0215(19971009)73:2<198::AID-IJC6>3.0.CO;2-R","article-title":"Melanoma and sun exposure: an overview of published studies","volume":"73","author":"Elwood","year":"1997","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.taap.2003.08.019_BIB14","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1751-1097.1970.tb06038.x","article-title":"Effects of ultraviolet radiation on the mitotic cycle and DNA, RNA and protein synthesis in mammalian epidermis in vivo","volume":"12","author":"Epstein","year":"1970","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.taap.2003.08.019_BIB15","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1524-4725.1988.tb03373.x","article-title":"Risk factors for the development of malignant melanoma I. Review of case-control studies","volume":"14","author":"Evans","year":"1988","journal-title":"J. Dermatol. Surg. Oncol."},{"key":"10.1016\/j.taap.2003.08.019_BIB16","first-page":"25","article-title":"Ultraviolet-induced pigmentary changes: benefits and hazards","volume":"vol. 15","author":"Fitzpatrick","year":"1986"},{"key":"10.1016\/j.taap.2003.08.019_BIB17","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF03401664","article-title":"The CDKN2 (p16) gene and human cancer","volume":"3","author":"Foulkes","year":"1997","journal-title":"Mol. Med."},{"key":"10.1016\/j.taap.2003.08.019_BIB18","doi-asserted-by":"crossref","first-page":"10557","DOI":"10.1073\/pnas.89.21.10557","article-title":"Homozygous deletions within human chromosome band 9p21 in melanoma","volume":"89","author":"Fountain","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB20","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0092-8674(92)90122-S","article-title":"Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9","volume":"69","author":"Gailani","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.taap.2003.08.019_BIB21","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/1076-0512(95)00570-6","article-title":"The epidemiology of skin cancer","volume":"22","author":"Gloster","year":"1996","journal-title":"Dermatol. Surg."},{"key":"10.1016\/j.taap.2003.08.019_BIB22","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.1365-2133.1988.tb03489.x","article-title":"311 nm UVB phototherapy\u2014An effective treatment for psoriasis","volume":"119","author":"Green","year":"1988","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB23","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1002\/(SICI)1097-0142(19991201)86:11+<2464::AID-CNCR3>3.0.CO;2-F","article-title":"The genetics of hereditary melanoma and naevi 1998 update","volume":"86","author":"Greene","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.taap.2003.08.019_BIB24","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1073\/pnas.87.2.643","article-title":"Two oncogenes v-fos and v-ras, cooperate to convert normal keratinocytes to squamous cell carcinoma","volume":"87","author":"Greenhalgh","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB25","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/ng0795-351","article-title":"Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds","volume":"10","author":"Gruis","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1016\/j.taap.2003.08.019_BIB26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0190-9622(88)70153-X","article-title":"Cutaneous melanomas in patients treated with psoralen plus ultraviolet A","volume":"19","author":"Gupta","year":"1988","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB27","first-page":"203","article-title":"High levels of p53 protein in UV-irradiated normal human skin","volume":"8","author":"Hall","year":"1993","journal-title":"Oncogene"},{"key":"10.1016\/j.taap.2003.08.019_BIB28","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/(SICI)1098-2264(200005)28:1<45::AID-GCC6>3.0.CO;2-F","article-title":"Mutation screening of the CDKN2A promoter in melanoma families","volume":"28","author":"Harland","year":"2000","journal-title":"Genes, Chromosomes Cancer"},{"key":"10.1016\/j.taap.2003.08.019_BIB29","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/0092-8674(93)90499-G","article-title":"The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases","volume":"75","author":"Harper","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.taap.2003.08.019_BIB30","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1440-0960.1976.tb00589.x","article-title":"Immunosuppressive drug therapy potentiator of skin tumors in five patients with lymphoma","volume":"17","author":"Hill","year":"1976","journal-title":"Aust. J. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB31","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1126\/science.285.5429.898","article-title":"Fas ligand: a sensor for DNA damage critical in skin cancer etiology","volume":"285","author":"Hill","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.taap.2003.08.019_BIB32","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1126\/science.1905840","article-title":"p53 mutation in human cancers","volume":"253","author":"Hollstein","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.taap.2003.08.019_BIB33","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0190-9622(94)70240-3","article-title":"Photochemotherapy beyond psoriasis","volume":"31","author":"Honig","year":"1994","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB34","series-title":"Dermatology in General Medicine","first-page":"2880","article-title":"Photochemotherapy and photodynamic therapy","author":"Honigsmann","year":"1999"},{"key":"10.1016\/j.taap.2003.08.019_BIB35","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1001\/archderm.113.4.436","article-title":"Incidence of skin carcinoma after renal transplantation","volume":"113","author":"Hoxtell","year":"1977","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB36","doi-asserted-by":"crossref","first-page":"4827","DOI":"10.1073\/pnas.93.10.4827","article-title":"Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest","volume":"93","author":"Huang","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB37","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/ng0994-15","article-title":"Germline mutations in familial melanoma","volume":"8","author":"Hussussian","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1016\/j.taap.2003.08.019_BIB38","doi-asserted-by":"crossref","first-page":"13221","DOI":"10.1016\/S0021-9258(19)38640-5","article-title":"8-Hydroxydeoxyguanosine formation at the 5\u2032 site of 5\u2032-GG-3\u2032 sequences in double-stranded DNA by UV radiation with riboflavin","volume":"268","author":"Ito","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.taap.2003.08.019_BIB39","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1751-1097.1996.tb05657.x","article-title":"PUVA treatment selectively induces a cell cycle block and subsequent apoptosis in human T-lymphocytes","volume":"63","author":"Johnson","year":"1996","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.taap.2003.08.019_BIB40","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.8153634","article-title":"A cell cycle regulator potentially involved in genesis of many tumor types","volume":"264","author":"Kamb","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.taap.2003.08.019_BIB41","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0092-8674(00)80452-3","article-title":"Tumor suppression at the INK4a locus mediated by the alternative reading frame product p19(ARF)","volume":"91","author":"Kamijo","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.taap.2003.08.019_BIB42","series-title":"Basal and squamous cell skin cancers of the head and neck","first-page":"25","article-title":"Molecular biology of skin carcinomas","author":"Kanjilal","year":"1996"},{"key":"10.1016\/j.taap.2003.08.019_BIB43","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/0092-8674(92)90593-2","article-title":"A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia","volume":"71","author":"Kastan","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.taap.2003.08.019_BIB44","series-title":"Photodamage","first-page":"51","article-title":"Molecular and cellular effects of UV radiation relevant to chronic photodamage","author":"Kochevar","year":"1995"},{"key":"10.1016\/j.taap.2003.08.019_BIB45","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1046\/j.1523-1747.2003.12085.x","article-title":"High frequency of ultraviolet mutations at the INK4a-ARF locus in squamous cell carcinomas from psoralen-plus-ultraviolet-A-treated psoriasis patients","volume":"120","author":"Kreimer-Erlacher","year":"2003","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB46","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/1523-1747.ep12542071","article-title":"Systemic suppression of contact hypersensitivity in mice by psoralen plus UVA radiation (PUVA)","volume":"81","author":"Kripke","year":"1983","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB47","doi-asserted-by":"crossref","first-page":"7516","DOI":"10.1073\/pnas.89.16.7516","article-title":"Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice","volume":"89","author":"Kripke","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB48","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1006\/bbrc.1997.6217","article-title":"Mutations of the INK4a locus in squamous cell carcinomas of human skin","volume":"232","author":"Kubo","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.taap.2003.08.019_BIB49","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/358015a0","article-title":"p53, guardian of the genome","volume":"358","author":"Lane","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.taap.2003.08.019_BIB50","doi-asserted-by":"crossref","first-page":"507","DOI":"10.2340\/0001555562507512","article-title":"Is UVB treatment of psoriasis safe? A study of extensively UVB-treated psoriasis patients compared with a matched control group","volume":"62","author":"Larko","year":"1982","journal-title":"Acta Dermatovenerol. (Stockh.)"},{"key":"10.1016\/j.taap.2003.08.019_BIB51","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/095466301317085390","article-title":"Adverse effects with PUVA and UVB phototherapy","volume":"12","author":"Laube","year":"2001","journal-title":"J. Dermatol. Treat."},{"key":"10.1016\/j.taap.2003.08.019_BIB52","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0190-9622(95)90184-1","article-title":"Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skin","volume":"32","author":"Lavker","year":"1995","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB53","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0968-0004(00)89088-X","article-title":"Nucleotide excision repair and the link with transcription","volume":"20","author":"Lehmann","year":"1995","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.taap.2003.08.019_BIB54","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1006\/excr.1997.3514","article-title":"Fas\/Fas ligand interaction contributes to UV-induced apoptosis in human keratinocytes","volume":"232","author":"Leverkus","year":"1997","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB55","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0140-6736(91)90083-2","article-title":"PUVA and cancer: a large-scale epidemiological study","volume":"338","author":"Lindeloef","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.taap.2003.08.019_BIB56","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1046\/j.1365-2133.1999.02928.x","article-title":"PUVA and cancer risk: the Swedish follow-up study","volume":"141","author":"Lindeloef","year":"1999","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB57","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1046\/j.1523-1747.1998.00316.x","article-title":"PUVA inhibits DNA replication, but not gene transcription at nonlethal dosages","volume":"111","author":"Luftl","year":"1998","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB58","first-page":"2995","article-title":"A novel p16INK4a transcript","volume":"55","author":"Mao","year":"1995","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB59","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1046\/j.1365-2230.2000.00693.x","article-title":"Epidemiology of melanoma","volume":"25","author":"Marks","year":"2001","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB60","doi-asserted-by":"crossref","first-page":"D765","DOI":"10.2741\/matsumur","article-title":"Molecular mechanisms of photocarcinogenesis","volume":"7","author":"Matsumura","year":"2002","journal-title":"Front. Biosci."},{"key":"10.1016\/j.taap.2003.08.019_BIB61","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/1523-1747.ep12321051","article-title":"High prevalence of mutations in the p53 gene in poorly differentiated squamous cell carcinomas in xeroderma pigmentosum patients","volume":"105","author":"Matsumura","year":"1995","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB63","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0190-9622(80)80075-2","article-title":"Incidence of skin cancers in patients with atopic dermatitis treated with coal tar","volume":"3","author":"Maughan","year":"1980","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB64","series-title":"Dermatology in General Medicine","first-page":"1555","article-title":"Acute effects on ultraviolet radiation on the skin","author":"McGregor","year":"1999"},{"key":"10.1016\/j.taap.2003.08.019_BIB65","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/j.1751-1097.1989.tb05578.x","article-title":"The biology of the (6-4) photoproduct","volume":"49","author":"Mitchell","year":"1989","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.taap.2003.08.019_BIB66","first-page":"299","article-title":"Suppression of delayed-type hypersensitivity to histocompatibility antigens by ultraviolet radiation","volume":"62","author":"Molendijk","year":"1987","journal-title":"Immunology"},{"key":"10.1016\/j.taap.2003.08.019_BIB67","first-page":"243","article-title":"In vivo effects of psoralens plus longwave ultraviolet radiation on immunity","volume":"66","author":"Morison","year":"1984","journal-title":"Natl. Cancer Inst. Monogr."},{"key":"10.1016\/j.taap.2003.08.019_BIB68","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1383-5742(01)00057-6","article-title":"Mutations in apoptosis genes: a pathogenetic factor for human disease","volume":"488","author":"Mullauer","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB69","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1084\/jem.188.11.2033","article-title":"p53 activates the CD95 (APO1\/Fas) gene in response to DNA damage by anticancer drugs","volume":"188","author":"Muller","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2003.08.019_BIB70","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/1523-1747.ep12319764","article-title":"p53 mutation in squamous cell carcinomas from psoriasis patients treated with psoralen plus UVA (PUVA)","volume":"109","author":"Nataraj","year":"1997","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB71","doi-asserted-by":"crossref","first-page":"6398","DOI":"10.1073\/pnas.89.14.6398","article-title":"Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors","volume":"89","author":"Nelson","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB72","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/j.1751-1097.1994.tb05020.x","article-title":"Cytokine release by peripheral blood mononuclear cells is affected by 8-methoxypsoralen plus UV-A","volume":"59","author":"Neuner","year":"1994","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.taap.2003.08.019_BIB73","doi-asserted-by":"crossref","first-page":"7189","DOI":"10.1073\/pnas.91.15.7189","article-title":"Mutations in ras genes in cells cultured from mouse skin tumors induced by ultraviolet irradiation","volume":"91","author":"Nishigori","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB74","doi-asserted-by":"crossref","first-page":"10354","DOI":"10.1073\/pnas.93.19.10354","article-title":"Evidence that DNA damage triggers interleukin 10 cytokine production in UV-irradiated murine keratinocytes","volume":"93","author":"Nishigori","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB75","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1038\/sj.onc.1201542","article-title":"A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis","volume":"15","author":"Nishimori","year":"1997","journal-title":"Oncogene"},{"key":"10.1016\/j.taap.2003.08.019_BIB76","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/368753a0","article-title":"Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers","volume":"368","author":"Nobori","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.taap.2003.08.019_BIB77","first-page":"527","article-title":"Suppression of contact hypersensitivity in mice by ultraviolet irradiation is associated with defective antigen presentation","volume":"43","author":"Noonan","year":"1981","journal-title":"Immunology"},{"key":"10.1016\/j.taap.2003.08.019_BIB78","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1365-2230.1987.tb01936.x","article-title":"Persistent skin pain after PUVA","volume":"12","author":"Norris","year":"1987","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB79","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1084\/jem.189.4.711","article-title":"312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions","volume":"189","author":"Ozawa","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2003.08.019_BIB80","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1751-1097.1982.tb04362.x","article-title":"Erythema and melanogenesis action spectrum of normal human skin","volume":"36","author":"Parrish","year":"1982","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.taap.2003.08.019_BIB81","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1001\/archderm.135.7.834","article-title":"Treatment with UVB for psoriasis and non-melanoma skin cancer","volume":"135","author":"Pasker-de Jong","year":"1999","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB82","first-page":"291","article-title":"Effect of UVA, UVB and psoralen on in vivo human melanin pigmentation","volume":"vol. 3","author":"Pathak","year":"1976"},{"key":"10.1016\/j.taap.2003.08.019_BIB83","first-page":"3946","article-title":"N-ras mutations in ultraviolet radiation-induced murine skin cancers","volume":"52","author":"Pierceall","year":"1992","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB84","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S0092-8674(00)81400-2","article-title":"The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53","volume":"92","author":"Pomerantz","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.taap.2003.08.019_BIB85","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/(SICI)1096-9896(199901)187:1<112::AID-PATH250>3.0.CO;2-3","article-title":"The p53 pathway","author":"Prives","year":"1999","journal-title":"J. Pathol."},{"key":"10.1016\/j.taap.2003.08.019_BIB86","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0165-7992(91)90004-N","article-title":"Damage distribution and mutation spectrum: the case of 8-methoxypsoralen plus UV-A in mammalian cells","volume":"263","author":"Sage","year":"1991","journal-title":"Mutat. Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB87","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/sj.cdd.4401007","article-title":"p53 and Fas ligand are required for psoralen and UVA-induced apoptosis in mouse epidermal cells","volume":"5","author":"Santamaria","year":"2002","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.taap.2003.08.019_BIB88","doi-asserted-by":"crossref","first-page":"5001","DOI":"10.1093\/emboj\/17.17.5001","article-title":"The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2","volume":"17","author":"Scott","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.taap.2003.08.019_BIB89","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/366704a0","article-title":"A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D\/CDK4","volume":"366","author":"Serrano","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.taap.2003.08.019_BIB90","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/(SICI)1098-2264(200005)28:1<121::AID-GCC14>3.0.CO;2-O","article-title":"Characterization of chromosome 1 abnormalities in malignant melanomas","volume":"28","author":"Smedley","year":"2000","journal-title":"Genes, Chromosomes Cancer"},{"key":"10.1016\/j.taap.2003.08.019_BIB91","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.1038\/sj.onc.1202915","article-title":"p16 UV mutations in skin epithelial tumors","volume":"18","author":"Soufir","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.taap.2003.08.019_BIB92","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1056\/NEJM199004193221601","article-title":"Genital tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation","volume":"322","author":"Stern","year":"1990","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.taap.2003.08.019_BIB93","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1056\/NEJM199704103361501","article-title":"Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA)","volume":"336","author":"Stern","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.taap.2003.08.019_BIB94","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1093\/jnci\/90.17.1278","article-title":"Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer","volume":"90","author":"Stern","year":"1998","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.taap.2003.08.019_BIB95","series-title":"Photoimmunology","first-page":"95","article-title":"SALT: skin-associated lymphoid tissue","author":"Streilein","year":"1983"},{"key":"10.1016\/j.taap.2003.08.019_BIB96","series-title":"Basal and squamous cell skin cancers of the head and neck","first-page":"1","article-title":"Epidemiology of basal and squamous cell carcinomas of the skin","author":"Strom","year":"1996"},{"key":"10.1016\/j.taap.2003.08.019_BIB97","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0190-9622(93)70283-Y","article-title":"PUVA, UVB, psoriasis, and nonmelanoma skin cancer","volume":"29","author":"Studniberg","year":"1993","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.taap.2003.08.019_BIB98","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1073\/pnas.89.4.1159","article-title":"Mechanism of SOS mutagenesis of UV-irradiated DNA: mostly error-free processing of deaminated cytosine","volume":"89","author":"Tessman","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.taap.2003.08.019_BIB99","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/bies.950180309","article-title":"UV damage and repair mechanisms in mammalian cells","volume":"18","author":"Tornaletti","year":"1996","journal-title":"BioEssays"},{"key":"10.1016\/j.taap.2003.08.019_BIB100","doi-asserted-by":"crossref","first-page":"D684","DOI":"10.2741\/ullrich","article-title":"Photoimmune suppression and photocarcinogenesis","volume":"7","author":"Ullrich","year":"2002","journal-title":"Front. Biosci."},{"key":"10.1016\/j.taap.2003.08.019_BIB101","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/ng1195-328","article-title":"Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans","volume":"11","author":"Valverde","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1016\/j.taap.2003.08.019_BIB102","doi-asserted-by":"crossref","first-page":"340","DOI":"10.2165\/00002018-199308050-00002","article-title":"Minimising the risks of PUVA treatment","volume":"8","author":"Van Praag","year":"1993","journal-title":"Drug Saf."},{"key":"10.1016\/j.taap.2003.08.019_BIB103","first-page":"2510","article-title":"Accumulation of p16CDKN2A in response to ultraviolet irradiation correlates with late S\u2013G2-phase cell cycle delay","volume":"56","author":"Wang","year":"1996","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2003.08.019_BIB104","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1023\/A:1008980919928","article-title":"Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies","volume":"12","author":"Whiteman","year":"2001","journal-title":"CCC, Cancer Causes Control"},{"key":"10.1016\/j.taap.2003.08.019_BIB105","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1146\/annurev.bi.65.070196.001031","article-title":"DNA repair in eukaryotes","volume":"65","author":"Wood","year":"1996","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.taap.2003.08.019_BIB106","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/372773a0","article-title":"Sunburn and p53 in the onset of skin cancer","volume":"372","author":"Ziegler","year":"1994","journal-title":"Nature"}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X03004952?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X03004952?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T16:52:52Z","timestamp":1734195172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X03004952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":104,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0041008X03004952"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2003.08.019","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}