{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:13:03Z","timestamp":1784693583980,"version":"3.55.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.taap.2007.08.003","type":"journal-article","created":{"date-parts":[[2007,8,18]],"date-time":"2007-08-18T11:16:34Z","timestamp":1187435794000},"page":"22-29","source":"Crossref","is-referenced-by-count":30,"title":["Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis"],"prefix":"10.1016","volume":"226","author":[{"given":"Sae-Gwang","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Kil","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Woong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se-Kwon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-Kyo","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi-Seon","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung Hyun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Su","family":"Yea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inhak","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Il-Whan","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2007.08.003_bib1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.bbamcr.2003.09.003","article-title":"Substance P induces TNF-alpha and IL-6 production through NF-kappaB in peritoneal mast cells","volume":"1643","author":"Azzolina","year":"2003","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.taap.2007.08.003_bib2","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1126\/science.270.5234.286","article-title":"Immunosuppression by glucocorticoids: inhibition of NF-\u03baB activity through induction of I O B synthesis","volume":"270","author":"Auphan","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.taap.2007.08.003_bib3","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1146\/annurev.immunol.14.1.649","article-title":"The NF-kappaB and I-kappaB proteins: new discoveries and insights","volume":"14","author":"Baldwin","year":"1996","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib4","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1056\/NEJM199704103361506","article-title":"Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases","volume":"336","author":"Barnes","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.taap.2007.08.003_bib5","first-page":"97","article-title":"Perspectives in platelet-activating factor research","volume":"39","author":"Braquet","year":"1987","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.taap.2007.08.003_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0165-2478(97)00115-6","article-title":"Tumor necrosis factor (TNF-\u03b1) activates human adenoidal and cutaneous mast cells to histamine secretion","volume":"59","author":"Brzezinska-Blaszczyk","year":"1997","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.taap.2007.08.003_bib7","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1365-2249.1995.tb03711.x","article-title":"Occurrence of disseminated intravascular coagulation (DIC) in active systemic anaphylaxis: role of platelet-activating factor","volume":"100","author":"Choi","year":"1995","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib8","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1084\/jem.188.9.1587","article-title":"Immunoglobulin E-dependent active fatal anaphylaxis in mast cell-deficient mice","volume":"188","author":"Choi","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2007.08.003_bib10","doi-asserted-by":"crossref","first-page":"5139","DOI":"10.4049\/jimmunol.166.8.5139","article-title":"Platelet-activating factor-induced early activation of NF-\u03baB plays a crucial role for organ clearance of Candida albicans","volume":"166","author":"Choi","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1084\/jem.20022129","article-title":"Platelet-activating factor-mediated NF-\u03baB dependency of a late anaphylactic reaction","volume":"198","author":"Choi","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2007.08.003_bib11","doi-asserted-by":"crossref","first-page":"6827","DOI":"10.4049\/jimmunol.163.12.6827","article-title":"NF-\u03baB\/Rel transcription factor: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation","volume":"163","author":"Donovan","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib12","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1073\/pnas.90.6.2399","article-title":"Inhibitors of human immunodeficiency virus integrase","volume":"90","author":"Fesen","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.taap.2007.08.003_bib50","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1093\/oxfordjournals.humrep.a019202","article-title":"Effect of platelet activating factor on embryonic development and implantation in the mouse","volume":"11","author":"Fukuda","year":"1996","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.taap.2007.08.003_bib13","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1146\/annurev.immunol.16.1.225","article-title":"NF-\u03baB and Rel proteins: evolutionarily conserved mediators of immune responses","volume":"16","author":"Ghosh","year":"1998","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib14","first-page":"1809","article-title":"NF-\u03baB-dependency of platelet-activating factor-induced angiogenesis","volume":"62","author":"Ko","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2007.08.003_bib15","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1084\/jem.174.1.103","article-title":"Release of both preformed and newly synthesized tumor necrosis factor alpha (TNF-alpha)\/cachectin by mouse mast cells stimulated via the Fc epsilon RI: a mechanism for the sustained action of mast cell-derived TNF-alpha during IgE-dependent biological responses","volume":"174","author":"Gordon","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2007.08.003_bib16","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.4049\/jimmunol.147.8.2455","article-title":"Antigen-specific inhibition of ongoing murine IgE responses. II. Inhibition of IgE responses induced by treatment with glutaraldehyde-modified allergens is paralleled by reciprocal increases in IgG2a synthesis","volume":"147","author":"Hayglass","year":"1991","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib17","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000234031","article-title":"Immune response potential of mast cell-deficient mice W\/Wv mice","volume":"80","author":"Ha","year":"1986","journal-title":"Int. Arch. Allergy Appl. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib18","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1002\/(SICI)1521-4141(199904)29:04<1334::AID-IMMU1334>3.0.CO;2-0","article-title":"Glucocorticoids prevent NF-\u03baB activation by inhibiting the early release of platelet-activating factor in response to lipopolysaccharide","volume":"29","author":"Han","year":"1999","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib19","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1159\/000055567","article-title":"Topically applied water extract of propolis of to suppress corneal neovascularization in rabbits","volume":"31","author":"Hepsen","year":"1999","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.taap.2007.08.003_bib20","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1161\/01.ATV.0000148404.24271.fc","article-title":"Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient mice","volume":"25","author":"Hishikawa","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.taap.2007.08.003_bib21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/pulp.1995.1004","article-title":"The effects of tumor-necrosis-factor on mediator release from human lung","volume":"8","author":"Hughes","year":"1995","journal-title":"Pulm. Pharmacol."},{"key":"10.1016\/j.taap.2007.08.003_bib22","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1007\/s11064-004-7038-y","article-title":"Caffeic acid phenethyl ester exerts a neuroprotective effect on CNS against pentylenetetrazol-induced seizures in mice","volume":"29","author":"Ilhan","year":"2004","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.taap.2007.08.003_bib24","first-page":"2662","article-title":"Augmentation of tumor metastasis by platelet-activating factor","volume":"56","author":"Im","year":"1996","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2007.08.003_bib23","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.1002\/eji.1830271109","article-title":"Involvement of nuclear factor-\u03baB in platelet-activating factor-mediated tumor necrosis factor-alpha expression","volume":"27","author":"Im","year":"1997","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib25","first-page":"60","article-title":"Biology of immunoglobulin E. Molecular basis of reaginic hypersensitivity","volume":"19","author":"Ishizaka","year":"1975","journal-title":"Prog. Allergy"},{"key":"10.1016\/j.taap.2007.08.003_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2776(08)60618-5","article-title":"NF-\u03baB and Rel proteins in innate immunity","volume":"58","author":"Kopp","year":"1995","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib27","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/0005-2760(84)90287-X","article-title":"Caffeic acid is a selective inhibitor for leukotriene biosynthesis","volume":"792","author":"Koshihara","year":"1984","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.taap.2007.08.003_bib28","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/267618a0","article-title":"Abrogation of reaginic antibodies with modified allergens","volume":"267","author":"Lee","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.taap.2007.08.003_bib29","doi-asserted-by":"crossref","first-page":"7907","DOI":"10.1021\/jf034729d","article-title":"Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis","volume":"51","author":"Liao","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.taap.2007.08.003_bib30","first-page":"428","article-title":"Induction of an auto-anti-IgE response in rats. III. Inhibition of a specific IgE response","volume":"66","author":"Marshall","year":"1989","journal-title":"Immunology"},{"key":"10.1016\/j.taap.2007.08.003_bib31","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1067\/mai.2000.104942","article-title":"Dependence of mast cell IgE-mediated cytokine production on nuclear factor-B activity","volume":"105","author":"Marquardt","year":"2000","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib32","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/0091-6749(92)90107-D","article-title":"Passive cutaneous anaphylaxis in mouse skin is associated with local accumulation of interleukin-6 mRNA and immunoreactive interleukin-6 protein","volume":"90","author":"Mican","year":"1992","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib33","first-page":"2347","article-title":"Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation","volume":"59","author":"Michaluart","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2007.08.003_bib34","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1084\/jem.180.1.377","article-title":"Tumor necrosis factor-\u03b1-induced angiogenesis depends on in situ platelet-activating factor biosynthesis","volume":"180","author":"Montrucchio","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.taap.2007.08.003_bib35","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/205199b0","article-title":"Mechanism of anaphylactic death in the mouse","volume":"205","author":"Munoz","year":"1965","journal-title":"Nature"},{"key":"10.1016\/j.taap.2007.08.003_bib36","doi-asserted-by":"crossref","first-page":"9090","DOI":"10.1073\/pnas.93.17.9090","article-title":"Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B","volume":"93","author":"Natarajan","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.taap.2007.08.003_bib38","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1159\/000233965","article-title":"Cyclosporin A-induced suppression of ongoing IgE antibody formation in the mouse","volume":"79","author":"Okudaira","year":"1986","journal-title":"Int. Arch. Allergy Appl. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib39","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000026427","article-title":"Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation","volume":"7","author":"Orban","year":"2000","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.taap.2007.08.003_bib40","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1248\/bpb.28.1928","article-title":"Effects of local administration of propolis and its polyphenolic compounds on tumor formation and growth","volume":"28","author":"Orsolic","year":"2005","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.taap.2007.08.003_bib41","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/BF02975325","article-title":"Suppressive effects of propolis in rat adjuvant arthritis","volume":"22","author":"Park","year":"1999","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.taap.2007.08.003_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2776(08)60496-4","article-title":"Lymphokine and cytokine production by Fc RI+ cells","volume":"53","author":"Paul","year":"1993","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib43","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.4049\/jimmunol.161.9.4768","article-title":"Fc\u03b5RI-mediated induction of TNF-\u03b1 gene expression in the RBL-2H3 mast cell line: regulation by a novel NF-\u03baB-like nuclear binding complex","volume":"161","author":"Pelletier","year":"1998","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib44","doi-asserted-by":"crossref","first-page":"204","DOI":"10.7326\/0003-4819-107-2-204","article-title":"Immediate hypersensitivity reactions to beta-lactam antibiotics","volume":"107","author":"Saxon","year":"1987","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.taap.2007.08.003_bib45","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1126\/science.270.5234.283","article-title":"Role of transcriptional activation of I O B \u00a7 in mediation of immunosuppression by glucocorticoids","volume":"270","author":"Scheinman","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.taap.2007.08.003_bib46","doi-asserted-by":"crossref","first-page":"183","DOI":"10.4049\/jimmunol.156.1.183","article-title":"B cells from p50\/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching","volume":"156","author":"Snapper","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2007.08.003_bib47","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1365-2222.1991.tb03200.x","article-title":"Tumour necrosis factor stimulates human skin mast cells to release histamine and tryptase","volume":"21","author":"Van Overveld","year":"1991","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.taap.2007.08.003_bib48","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0031-6989(86)90044-5","article-title":"Pharmacological control of the in vivo passive anaphylactic shock by the PAF-acether antagonist compound BN 52021","volume":"18, Suppl:","author":"Vilain","year":"1986","journal-title":"Pharmacol. Res. Commun."},{"key":"10.1016\/j.taap.2007.08.003_bib49","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1172\/JCI115016","article-title":"Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent: partial inhibition of the reaction with antiserum against tumor necrosis factor-\u03b1","volume":"87","author":"Wershil","year":"1991","journal-title":"J. Clin. Invest."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X07003560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X07003560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T20:55:53Z","timestamp":1684011353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X07003560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0041008X07003560"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2007.08.003","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}