{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:39:57Z","timestamp":1790919597853,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.taap.2012.08.035","type":"journal-article","created":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T19:18:11Z","timestamp":1347391091000},"page":"335-341","source":"Crossref","is-referenced-by-count":10,"title":["A novel mechanism of filaggrin induction and sunburn prevention by \u03b2-damascenone in Skh-1 mice"],"prefix":"10.1016","volume":"265","author":[{"given":"Ahmed N.","family":"Uddin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivica","family":"Labuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredric J.","family":"Burns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2012.08.035_bb0005","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1369\/jhc.4A6300.2004","article-title":"Ultrastructural localization of caspase-14 in human epidermis","volume":"52","author":"Alibardi","year":"2004","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.taap.2012.08.035_bb0010","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1269\/jrr.43.S229","article-title":"The action of a dietary retinoid on gene expression and cancer induction in electron-irradiated rat skin","volume":"43","author":"Burns","year":"2002","journal-title":"J. Radiat. Res."},{"key":"10.1016\/j.taap.2012.08.035_bb0020","series-title":"Environmental and Occupational Medicine","first-page":"1262","article-title":"Radiation carcinogenesis: mechanisms of induction and prevention","author":"Burns","year":"2007"},{"key":"10.1016\/j.taap.2012.08.035_bb0025","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s00411-007-0106-3","article-title":"Induction and prevention of carcinogenesis in rat skin exposed to space radiation","volume":"46","author":"Burns","year":"2007","journal-title":"Radiat. Environ. Biophys."},{"key":"10.1016\/j.taap.2012.08.035_bb0015","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1289\/ehp.10978","article-title":"Mechanism of selenium-induced inhibition of arsenic-enhanced UVR carcinogenesis in mice","volume":"116","author":"Burns","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.taap.2012.08.035_bb0030","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/nrm1619","article-title":"The cornified envelope: a model of cell death in the skin","volume":"6","author":"Candi","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.taap.2012.08.035_bb0035","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/ncb1597","article-title":"Caspase-14 protects against epidermal UVB photodamage and water loss","volume":"9","author":"Denecker","year":"2007","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.taap.2012.08.035_bb0040","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1083\/jcb.200709098","article-title":"Caspase-14 reveals its secrets","volume":"180","author":"Denecker","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.taap.2012.08.035_bb0045","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1046\/j.1523-1747.2000.00205.x","article-title":"Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation","volume":"115","author":"Eckhart","year":"2000","journal-title":"J. Investig. Dermatol."},{"key":"10.1016\/j.taap.2012.08.035_bb0050","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1002\/mnfr.200800492","article-title":"Identification of 3-hydroxy beta damascenone and related carotenoid-derived aroma compounds as novel potent inducers of Nr2-mediated phase 2 response with concomitant anti-inflammatory activity","volume":"53","author":"Gerhauser","year":"2009","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.taap.2012.08.035_bb0055","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1056\/NEJM199009203231204","article-title":"A clinical trial of beta carotene to prevent basal-cell and squamous-cell cancers of the skin","volume":"323","author":"Greenberg","year":"1990","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.taap.2012.08.035_bb0060","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1207\/S15327914NC372_7","article-title":"Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin","volume":"37","author":"Hakim","year":"2000","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.taap.2012.08.035_bb0065","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s004030000164","article-title":"Protective effects of sunscreening agents on photocarcinogenesis, photoaging, and DNA damage in XPA gene knockout mice","volume":"292","author":"Horiki","year":"2000","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.taap.2012.08.035_bb0070","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1111\/j.1398-9995.2010.02540.x","article-title":"Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity","volume":"66","author":"Kezic","year":"2011","journal-title":"Allergy"},{"key":"10.1016\/j.taap.2012.08.035_bb0075","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1354\/vp.43-1-36","article-title":"Expression of terminal differentiation proteins defines stages of mouse mammary gland development","volume":"43","author":"Mikaelian","year":"2006","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.taap.2012.08.035_bb0080","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1038\/jid.2010.115","article-title":"Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model","volume":"130","author":"Mildner","year":"2010","journal-title":"J. Investig. Dermatol."},{"key":"10.1016\/j.taap.2012.08.035_bb0085","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1080\/01635581003693066","article-title":"Adipose tissue accumulation of d-limonene with the consumption of a lemonade preparation rich in d-limonene content","volume":"62","author":"Miller","year":"2010","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.taap.2012.08.035_bb0090","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/ncb0607-621","article-title":"Caspase-14 and epidermis maturation","volume":"9","author":"Nicotera","year":"2007","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.taap.2012.08.035_bb0095","first-page":"899","article-title":"Role of the epidermal barrier in atopic dermatitis","volume":"7","author":"Proksch","year":"2009","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"10.1016\/j.taap.2012.08.035_bb0100","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1006\/taap.2001.9277","article-title":"Arsenite is a cocarcinogen with solar ultraviolet radiation for mouse skin: an animal model for arsenic carcinogenesis","volume":"176","author":"Rossman","year":"2001","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2012.08.035_bb0105","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/1047-8477(90)90071-J","article-title":"Biosynthetic pathways of filaggrin and loricrin\u2013two major proteins expressed by terminally differentiated epidermal keratinocytes","volume":"104","author":"Steven","year":"1990","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.taap.2012.08.035_bb0110","first-page":"293","article-title":"Harlequin ichthyosis (ichq): a juvenile lethal mouse mutation with ichthyosiform dermatitis","volume":"151","author":"Sundberg","year":"1997","journal-title":"Am. J. Pathol."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X12003961?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X12003961?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T22:31:17Z","timestamp":1542753077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X12003961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0041008X12003961"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2012.08.035","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}