{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:50:23Z","timestamp":1790621423480,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T00:00:00Z","timestamp":1552608000000},"content-version":"am","delay-in-days":348,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100006190","name":"Research and Development","doi-asserted-by":"publisher","award":["2017YFC1001300"],"award-info":[{"award-number":["2017YFC1001300"]}],"id":[{"id":"10.13039\/100006190","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81430089"],"award-info":[{"award-number":["81430089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81501269"],"award-info":[{"award-number":["81501269"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81673524"],"award-info":[{"award-number":["81673524"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703241"],"award-info":[{"award-number":["81703241"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hubei Province Health and Family Planning Scientific Research Project","award":["WJ2017C0003"],"award-info":[{"award-number":["WJ2017C0003"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.taap.2018.03.007","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T01:55:36Z","timestamp":1520474136000},"page":"36-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Autophagy as a compensation mechanism participates in ethanol-induced fetal adrenal dysfunction in female rats"],"prefix":"10.1016","volume":"345","author":[{"given":"Hegui","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Ao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5300-8661","authenticated-orcid":false,"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2018.03.007_bb0005","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3892\/mmr.2014.2258","article-title":"Insulin-like growth factors in embryonic and fetal growth and skeletal development (review)","volume":"10","author":"Agrogiannis","year":"2014","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.taap.2018.03.007_bb0010","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1203\/01.PDR.0000179392.59060.93","article-title":"Expression of the IGF system in human adrenal tissues from early infancy to late puberty: implications for the development of adrenarche","volume":"58","author":"Baquedano","year":"2005","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.taap.2018.03.007_bb0015","doi-asserted-by":"crossref","first-page":"5446","DOI":"10.1210\/jc.2005-0836","article-title":"Expression profiles for steroidogenic enzymes in adrenocortical disease","volume":"90","author":"Bassett","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.taap.2018.03.007_bb0020","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1210\/me.2002-0056","article-title":"Transcription of cholesterol side-chain cleavage cytochrome P450 in the placenta: activating protein-2 assumes the role of steroidogenic factor-1 by binding to an overlapping promoter element","volume":"16","author":"Ben-Zimra","year":"2002","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.taap.2018.03.007_bb0025","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.4161\/auto.21376","article-title":"Autophagy is a protective response to ethanol neurotoxicity","volume":"8","author":"Chen","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2018.03.007_bb0030","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1159\/000046892","article-title":"Ethanol consumption and liver mitochondria function","volume":"10","author":"Cunningham","year":"2001","journal-title":"Biol. Signals Recept."},{"key":"10.1016\/j.taap.2018.03.007_bb0035","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1677\/joe.0.1790131","article-title":"Dexamethasone does not exert direct intracellular feedback on steroidogenesis in human adrenal NCI-H295A cells","volume":"179","author":"Dardis","year":"2003","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.taap.2018.03.007_bb0040","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1196\/annals.1365.047","article-title":"Fetal growth restriction and postnatal development","volume":"1092","author":"Eleftheriades","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.taap.2018.03.007_bb1000","doi-asserted-by":"crossref","first-page":"D5","DOI":"10.1093\/nar\/gkp967","article-title":"Database resources of the national center for biotechnology information","author":"Sayers","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.taap.2018.03.007_bb0045","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/toxsci\/kfi209","article-title":"A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity","volume":"86","author":"Gohlke","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2018.03.007_bb0050","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1073\/pnas.0308710100","article-title":"A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts","volume":"101","author":"Hansson","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.taap.2018.03.007_bb0055","doi-asserted-by":"crossref","first-page":"re7","DOI":"10.1126\/scisignal.128re7","article-title":"Ethanol's molecular targets","volume":"1","author":"Harris","year":"2008","journal-title":"Sci. Signal."},{"key":"10.1016\/j.taap.2018.03.007_bb0060","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1210\/mend.15.5.0636","article-title":"Functions of the upstream and proximal steroidogenic factor 1 (SF-1)-binding sites in the CYP11A1 promoter in basal transcription and hormonal response","volume":"15","author":"Hu","year":"2001","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.taap.2018.03.007_bb0065","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.taap.2015.07.005","article-title":"Prenatal ethanol exposure-induced adrenal developmental abnormality of male offspring rats and its possible intrauterine programming mechanisms","volume":"288","author":"Huang","year":"2015","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2018.03.007_bb0070","first-page":"654","article-title":"Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases","volume":"8","author":"Ikeda","year":"1994","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.taap.2018.03.007_bb0075","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ymeth.2014.11.021","article-title":"LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells","volume":"75","author":"Jiang","year":"2015","journal-title":"Methods"},{"key":"10.1016\/j.taap.2018.03.007_bb0080","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.cmet.2008.08.013","article-title":"Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia","volume":"8","author":"Jung","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.taap.2018.03.007_bb0085","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.tem.2008.03.003","article-title":"IGF signaling defects as causes of growth failure and IUGR","volume":"19","author":"Klammt","year":"2008","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.taap.2018.03.007_bb0090","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/acel.12600","article-title":"Autophagy compensates impaired energy metabolism in CLPXP-deficient Podospora anserina strains and extends healthspan","volume":"16","author":"Knuppertz","year":"2017","journal-title":"Aging Cell"},{"key":"10.1016\/j.taap.2018.03.007_bb0095","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1038\/nature03029","article-title":"The role of autophagy during the early neonatal starvation period","volume":"432","author":"Kuma","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.taap.2018.03.007_bb0100","doi-asserted-by":"crossref","first-page":"323","DOI":"10.4161\/auto.4012","article-title":"LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization","volume":"3","author":"Kuma","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2018.03.007_bb0105","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.etp.2010.04.015","article-title":"Ethanol-induced inhibition of fetal hypothalamic-pituitary-adrenal axis due to prenatal overexposure to maternal glucocorticoid in mice","volume":"63","author":"Liang","year":"2011","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.taap.2018.03.007_bb0110","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S1047-2797(97)00081-1","article-title":"Low-to-moderate gestational alcohol use and intrauterine growth retardation, low birthweight, and preterm delivery","volume":"7","author":"Lundsberg","year":"1997","journal-title":"Ann. Epidemiol."},{"key":"10.1016\/j.taap.2018.03.007_bb0115","doi-asserted-by":"crossref","first-page":"524","DOI":"10.4161\/auto.5905","article-title":"Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle","volume":"4","author":"Mammucari","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2018.03.007_bb0120","doi-asserted-by":"crossref","first-page":"750","DOI":"10.2174\/138920111795470868","article-title":"Glucocorticoids in pregnancy","volume":"12","author":"Marciniak","year":"2011","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.taap.2018.03.007_bb0125","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.2105\/AJPH.2003.037093","article-title":"Maternal risk factors for fetal alcohol syndrome in the western cape province of South Africa: a population-based study","volume":"95","author":"May","year":"2005","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.taap.2018.03.007_bb0130","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.molmed.2007.05.003","article-title":"Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health","volume":"13","author":"Meaney","year":"2007","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.taap.2018.03.007_bb0135","first-page":"225","article-title":"Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy","volume":"63","author":"Mickiewicz","year":"2012","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.taap.2018.03.007_bb0140","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2183\/pjab.90.163","article-title":"Functional zonation of the rat adrenal cortex: the development and maintenance","volume":"90","author":"Mitani","year":"2014","journal-title":"Proc. Jpn. Acad. B Phys. Biol. Sci."},{"key":"10.1016\/j.taap.2018.03.007_bb0145","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/BF03403909","article-title":"Prevalence and predictors of health risk behaviours during early pregnancy: Saskatoon pregnancy and health study","volume":"88","author":"Muhajarine","year":"1997","journal-title":"Can. J. Public health"},{"key":"10.1016\/j.taap.2018.03.007_bb0150","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1471-2393-11-27","article-title":"Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure\u2014retrospective cohort study in an urban obstetric population in Ireland","volume":"11","author":"Mullally","year":"2011","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.taap.2018.03.007_bb0155","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2393-13-8","article-title":"Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes\u2014a prospective cohort study","volume":"13","author":"Murphy","year":"2013","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.taap.2018.03.007_bb0160","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1210\/jc.2009-0452","article-title":"Partial primary deficiency of insulin-like growth factor (IGF)-I activity associated with IGF1 mutation demonstrates its critical role in growth and brain development","volume":"94","author":"Netchine","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.taap.2018.03.007_bb0165","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.toxlet.2015.07.017","article-title":"Prenatal ethanol exposure induces the osteoarthritis-like phenotype in female adult offspring rats with a post-weaning high-fat diet and its intrauterine programming mechanisms of cholesterol metabolism","volume":"238","author":"Ni","year":"2015","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.taap.2018.03.007_bb0170","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000084092","article-title":"Adrenal function of low-birthweight children","volume":"8","author":"Ong","year":"2005","journal-title":"Endocr. Dev."},{"key":"10.1016\/j.taap.2018.03.007_bb0175","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0741-8329(92)90048-F","article-title":"Alcohol reduces the number of pheochromocytoma (PC12) cells in culture","volume":"9","author":"Pantazis","year":"1992","journal-title":"Alcohol"},{"key":"10.1016\/j.taap.2018.03.007_bb0180","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.tox.2014.03.011","article-title":"Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis","volume":"321","author":"Ping","year":"2014","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2018.03.007_bb0185","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003160","article-title":"Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice","volume":"9","author":"Pitetti","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.taap.2018.03.007_bb0190","first-page":"91","article-title":"IGF-I enhances cortisol secretion from guinea-pig adrenal gland: in vivo and in vitro study","volume":"20","author":"Raha","year":"2007","journal-title":"Int. J. Mol. Med."},{"issue":"Suppl. A","key":"10.1016\/j.taap.2018.03.007_bb0195","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1016\/j.placenta.2007.12.002","article-title":"Distinct actions of insulin-like growth factors (IGFs) on placental development and fetal growth: lessons from mice and guinea pigs","volume":"29","author":"Roberts","year":"2008","journal-title":"Placenta"},{"key":"10.1016\/j.taap.2018.03.007_bb0200","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1677\/JOE-07-0166","article-title":"Human adrenal corticocarcinoma NCI-H295R cells produce more androgens than NCI-H295A cells and differ in 3beta-hydroxysteroid dehydrogenase type 2 and 17,20 lyase activities","volume":"195","author":"Samandari","year":"2007","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.taap.2018.03.007_bb0205","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.taap.2013.11.009","article-title":"Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats","volume":"274","author":"Shen","year":"2014","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2018.03.007_bb0210","first-page":"3329","article-title":"Autophagy regulates adipose mass and differentiation in mice","volume":"119","author":"Singh","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.taap.2018.03.007_bb0215","doi-asserted-by":"crossref","first-page":"8368","DOI":"10.1158\/0008-5472.CAN-06-4064","article-title":"Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation","volume":"67","author":"Sirianni","year":"2007","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2018.03.007_bb0220","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.toxlet.2012.09.007","article-title":"Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation","volume":"214","author":"Tan","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.taap.2018.03.007_bb0225","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.acthis.2013.10.007","article-title":"Immunolocalization of cell cycle proteins (p57, p27, cyclin D3, PCNA and Ki67) in intrauterine growth retardation (IUGR) and normal human term placentas","volume":"116","author":"Unek","year":"2014","journal-title":"Acta Histochem."},{"issue":"Suppl. 1","key":"10.1016\/j.taap.2018.03.007_bb0230","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1016\/j.psyneuen.2007.03.014","article-title":"HPA axis programming by maternal undernutrition in the male rat offspring","volume":"32","author":"Vieau","year":"2007","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.taap.2018.03.007_bb0235","doi-asserted-by":"crossref","first-page":"R151","DOI":"10.1530\/JME-13-0241","article-title":"Autophagy in the endocrine glands","volume":"52","author":"Weckman","year":"2014","journal-title":"J. Mol. Endocrinol."},{"key":"10.1016\/j.taap.2018.03.007_bb0240","doi-asserted-by":"crossref","first-page":"833","DOI":"10.15288\/jsa.1999.60.833","article-title":"Knowledge of fetal alcohol syndrome (FAS) among natives in Northern Manitoba","volume":"60","author":"Williams","year":"1999","journal-title":"J. Stud. Alcohol"},{"key":"10.1016\/j.taap.2018.03.007_bb0245","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.toxlet.2014.01.023","article-title":"Prenatal ethanol exposure enhances the susceptibility to metabolic syndrome in offspring rats by HPA axis-associated neuroendocrine metabolic programming","volume":"226","author":"Xia","year":"2014","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.taap.2018.03.007_bb0250","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.taap.2012.08.016","article-title":"A hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in offspring rats of IUGR induced by prenatal caffeine ingestion","volume":"264","author":"Xu","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2018.03.007_bb0255","article-title":"Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats","volume":"7","author":"Xu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.taap.2018.03.007_bb0260","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.cmet.2010.04.005","article-title":"Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance","volume":"11","author":"Yang","year":"2010","journal-title":"Cell Metab."},{"key":"10.1016\/j.taap.2018.03.007_bb0265","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/jcbfm.1984.40","article-title":"Three-dimensional architecture of cerebral microvessels with a scanning electron microscope: a cerebrovascular casting method for fetal and adult rats","volume":"4","author":"Yoshida","year":"1984","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.taap.2018.03.007_bb0270","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.cmet.2007.11.004","article-title":"FoxO3 coordinately activates protein degradation by the autophagic\/lysosomal and proteasomal pathways in atrophying muscle cells","volume":"6","author":"Zhao","year":"2007","journal-title":"Cell Metab."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X18300851?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X18300851?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:44:38Z","timestamp":1758573878000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X18300851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":55,"alternative-id":["S0041008X18300851"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2018.03.007","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autophagy as a compensation mechanism participates in ethanol-induced fetal adrenal dysfunction in female rats","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2018.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}