{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T17:13:24Z","timestamp":1783790004717,"version":"3.55.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T00:00:00Z","timestamp":1562716800000},"content-version":"vor","delay-in-days":312,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004909","name":"Universidade Federal do Rio Grande do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004909","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.taap.2018.06.024","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T18:40:26Z","timestamp":1530124826000},"page":"138-146","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Energy drink and alcohol combination leads to kidney and liver alterations in rats"],"prefix":"10.1016","volume":"355","author":[{"given":"Marina Tuerlinckx","family":"Costa-Valle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Ducatti","family":"Tonieto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Altknecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila D.","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuryan","family":"F\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa V.","family":"Cestonaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"G\u00f6ethel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange C.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirna Bainy","family":"Leal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliane","family":"Dallegrave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Dutra","family":"Arbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2018.06.024_bb0005","series-title":"Robbins e Cotran: Patologia - Bases patol\u00f3gicas das doen\u00e7as","author":"Abbas","year":"2010"},{"key":"10.1016\/j.taap.2018.06.024_bb0010","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/1476-511X-10-166","article-title":"Gold nanoparticles induced cloudy swelling to hydropic degeneration, cytoplasmic hyaline vacuolation, polymorphism, binucleation, karyopyknosis, karyolysis, karyorrhexis and necrosis in the liver","volume":"10","author":"Abdelhalim","year":"2011","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.taap.2018.06.024_bb0015","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.pbb.2011.06.010","article-title":"Chronic coffee and caffeine ingestion effects on the cognitive function and antioxidant system of rat brains","volume":"99","author":"Abreu","year":"2011","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0020","first-page":"45","article-title":"Assessment of biochemical effect of \u201cPower Horse\u201d energy drink on hepatic, renal and histological functions in Sprague Dawley rats","volume":"1","author":"Akande","year":"2011","journal-title":"Ann. Rev. Res. Biol."},{"key":"10.1016\/j.taap.2018.06.024_bb0025","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1016\/j.addbeh.2013.04.003","article-title":"Alcohol mixed with energy drinks: are there associated negative consequences beyond hazardous drinking in college students?","volume":"38","author":"Berger","year":"2013","journal-title":"Addict. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0030","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4137\/NMI.S12215","article-title":"Influence of acute coffee consumption on postprandial oxidative stress","volume":"6","author":"Bloomer","year":"2013","journal-title":"Nutr. Metab. Insights"},{"key":"10.1016\/j.taap.2018.06.024_bb0035","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.neuint.2009.03.015","article-title":"Early long-term exposure with caffeine induces cross-sensitization to methylphenidate with involvement of DARPP-32 in adulthood of rats","volume":"55","author":"Boeck","year":"2009","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.taap.2018.06.024_bb0040","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.addbeh.2011.07.003","article-title":"Drinking patterns and risk behaviors associated with combined alcohol and energy drink consumption in college drinkers","volume":"36","author":"Brache","year":"2011","journal-title":"Addict. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0045","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.neulet.2011.02.050","article-title":"Caffeine improves attention deficit in neonatal 6-OHDA lesioned rats, an animal model of attention deficit hyperactivity disorder (ADHD)","volume":"494","author":"Caballero","year":"2011","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.taap.2018.06.024_bb0050","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/j.lfs.2004.03.010","article-title":"Possible anxiolytic effects of taurine in the mouse elevated plus-maze","volume":"75","author":"Chen","year":"2004","journal-title":"Life Sci."},{"key":"10.1016\/j.taap.2018.06.024_bb0055","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/nure.12148","article-title":"Influence of energy drink ingredients on mood and cognitive performance","volume":"72","author":"Childs","year":"2014","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.taap.2018.06.024_bb0065","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1080\/15287394.2017.1286901","article-title":"A reduction in DNA damage in neural tissue and peripheral blood of old mice treated with caffeine","volume":"80","author":"Damiani","year":"2017","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.taap.2018.06.024_bb0070","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.etap.2009.11.005","article-title":"Oxidative and nitrosative stress in experimental rat liver fibrosis: protective effect of taurine","volume":"29","author":"Devi","year":"2010","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.taap.2018.06.024_bb0075","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8725354","article-title":"Energy drink administration in combination with alcohol causes an inflammatory response and oxidative stress in the hippocampus and temporal cortex of rats","volume":"2016","author":"D\u00edaz","year":"2016","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.taap.2018.06.024_bb0080","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulfhydryl groups","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.taap.2018.06.024_bb0085","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0076-6879(90)86134-H","article-title":"Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal","volume":"186","author":"Esterbauer","year":"1990","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.taap.2018.06.024_bb0090","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0031-9384(04)00284-7","article-title":"Can energy drinks reduce the depressor effect of ethanol? An experimental study in mice","volume":"82","author":"Ferreira","year":"2004","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0095","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.pbb.2013.07.014","article-title":"Expression of behavioral sensitization to ethanol is increased by energy drink administration","volume":"110","author":"Ferreira","year":"2013","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0100","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ejphar.2007.09.017","article-title":"Taurine and ethanol interactions: behavioral effects in mice","volume":"578","author":"Ginsburg","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.taap.2018.06.024_bb0105","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.nut.2010.08.004","article-title":"Caffeine-not just a stimulant","volume":"26","author":"Glade","year":"2010","journal-title":"Nutrition"},{"key":"10.1016\/j.taap.2018.06.024_bb0110","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.mrgentox.2014.05.008","article-title":"Evaluation of genotoxicity in workers exposed to benzene and atmospheric pollutants","volume":"770","author":"G\u00f6ethel","year":"2014","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"key":"10.1016\/j.taap.2018.06.024_bb0115","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/nure.12137","article-title":"Implications of sleep and energy drink use for health disparities","volume":"72","author":"Grandner","year":"2014","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.taap.2018.06.024_bb0120","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1177\/1060028014541997","article-title":"Energy drink-induced acute kidney injury","volume":"48","author":"Greene","year":"2014","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.taap.2018.06.024_bb0125","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jpba.2006.07.030","article-title":"Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography-visible detection","volume":"43","author":"Grotto","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.taap.2018.06.024_bb0130","first-page":"46","article-title":"Energy drinks: health risks and toxicity","volume":"196","author":"Gunja","year":"2012","journal-title":"MJA"},{"key":"10.1016\/j.taap.2018.06.024_bb0135","first-page":"953","article-title":"Effects of consuming alcohol mixed with energy drinks versus consuming alcohol only on overall alcohol consumption and negative alcohol-related consequences","volume":"5","author":"Haan","year":"2012","journal-title":"Int. J. Gen. Med."},{"key":"10.1016\/j.taap.2018.06.024_bb0140","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.4065\/mcp.2010.0381","article-title":"Energy beverages: content and safety","volume":"85","author":"Higgins","year":"2010","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.taap.2018.06.024_bb0145","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1093\/clinchem\/27.7.1180","article-title":"Spectrophotometric assay for urinary N-acetyl-beta-d-glucosaminidase activity","volume":"27","author":"Horak","year":"1981","journal-title":"Clin. Chem."},{"key":"10.1016\/j.taap.2018.06.024_bb0150","first-page":"335","article-title":"The acute effects of caffeinated versus non-caffeinated alcoholic beverage on driving performance and attention\/reaction time","volume":"106","author":"Howland","year":"2010","journal-title":"Addict. Res. Rep."},{"key":"10.1016\/j.taap.2018.06.024_bb0155","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1039\/C3FO60597C","article-title":"Effect of taurine in chronic alcoholic patients","volume":"25","author":"Hsieh","year":"2014","journal-title":"Food Funct."},{"key":"10.1016\/j.taap.2018.06.024_bb0160","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0301-0082(99)00071-4","article-title":"Osmotic regulation of neuronal activity: a new role for taurine and glial cells in a hypothalamic neuroendocrine structure","volume":"62","author":"Hussy","year":"2000","journal-title":"Prog. Neuro. Biol."},{"key":"10.1016\/j.taap.2018.06.024_bb0165","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3109\/19390211.2011.615805","article-title":"Amelioration of alcohol-induced hepatotoxicity and oxidative stress in rats by acorus calamus","volume":"8","author":"Ilaiyaraja","year":"2011","journal-title":"J. Diet. Suppl."},{"key":"10.1016\/j.taap.2018.06.024_bb0170","first-page":"485","article-title":"Caffeine and taurine enhance endurance performance","volume":"30","author":"Imagawa","year":"2009","journal-title":"Physiol. Biochem."},{"key":"10.1016\/j.taap.2018.06.024_bb0175","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/j.fct.2010.03.033","article-title":"Oxidative stress parameters in rats exposed to fluoride and caffeine","volume":"48","author":"Inkielewicz-Stepniak","year":"2010","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.taap.2018.06.024_bb0180","first-page":"25","article-title":"Energy drinks: psychological effects and impact on well-being and quality of life-a literature review","volume":"9","author":"Ishak","year":"2012","journal-title":"Innov. Clin. Neurosci."},{"key":"10.1016\/j.taap.2018.06.024_bb0185","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s11010-011-1022-z","article-title":"Chronic alcohol intake-induced oxidative stress and apoptosis: role of cyp2e1 and calpain-1 in alcoholic cardiomyopathy","volume":"359","author":"Jing","year":"2012","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.taap.2018.06.024_bb0190","first-page":"688","article-title":"Histological, ultrastructural and physiological studies on the effect of different kinds of energy drinks on the liver of Wistar albino rat","volume":"8","author":"Khayyat","year":"2012","journal-title":"J. Am. Sci."},{"key":"10.1016\/j.taap.2018.06.024_bb0195","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.pbb.2006.02.007","article-title":"Effects of taurine on rat behaviors in three anxiety models","volume":"83","author":"Kong","year":"2006","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0200","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1093\/carcin\/bgs340","article-title":"Genotoxicity of alcohol is linked to DNA replication-associated damage and homologous recombination repair","volume":"34","author":"Kotova","year":"2013","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.taap.2018.06.024_bb0205","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.ajem.2016.02.068","article-title":"Cardiovascular responses to energy drinks in a healthy population: the C-energy study","volume":"34","author":"Kozik","year":"2016","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.taap.2018.06.024_bb0210","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.neulet.2017.04.050","article-title":"Energy drink enhances the behavioral effects of alcohol in adolescent mice","volume":"9","author":"Krahe","year":"2017","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.taap.2018.06.024_bb0215","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/apha.12365","article-title":"Physiological role of taurine - from organism to organelle","volume":"213","author":"Lambert","year":"2015","journal-title":"Acta Physiol."},{"key":"10.1016\/j.taap.2018.06.024_bb0220","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1681\/ASN.2006030221","article-title":"Urinary N-acetyl-\u03b2-(d)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure","volume":"18","author":"Liangos","year":"2007","journal-title":"JASN"},{"key":"10.1016\/j.taap.2018.06.024_bb0225","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/nrgastro.2015.35","article-title":"Alcoholic liver disease: mechanisms of injury and targeted treatment","volume":"12","author":"Louvet","year":"2015","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.taap.2018.06.024_bb0230","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1039\/C4FO00290C","article-title":"Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking?","volume":"5","author":"Ludwig","year":"2014","journal-title":"Food Funct."},{"issue":"6(1)","key":"10.1016\/j.taap.2018.06.024_bb0235","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3945\/an.114.007393","article-title":"Can energy drinks increase the desire for more alcohol?","volume":"2015","author":"Marczinski","year":"2015","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.taap.2018.06.024_bb0240","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.drugalcdep.2015.01.047","article-title":"A comprehensive review of the effects of mixing caffeinated energy drinks with alcohol","volume":"151","author":"Mcketin","year":"2015","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.taap.2018.06.024_bb0245","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00726-009-0458-x","article-title":"The impact of taurine- and beta-alanine supplemented diets on behavioral and neurochemical parameters in mice: antidepressant versus anxiolytic-like effects","volume":"39","author":"Murakami","year":"2010","journal-title":"Amino Acids"},{"key":"10.1016\/j.taap.2018.06.024_bb0250","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.mrgentox.2015.04.001","article-title":"In vivo comet assay of acrylonitrile, 9-aminoacridine hydrochloride monohydrate and ethanol in rats","volume":"786-788","author":"Nakagawa","year":"2015","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"key":"10.1016\/j.taap.2018.06.024_bb0255","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/465897","article-title":"Induction of oxidative stress in kidney","volume":"2012","author":"Ozbek","year":"2012","journal-title":"Int. J. Nephrol."},{"key":"10.1016\/j.taap.2018.06.024_bb0260","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.euroneuro.2012.04.011","article-title":"Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder","volume":"23","author":"Pandolfo","year":"2013","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.taap.2018.06.024_bb0265","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1111\/acer.12086","article-title":"The impact of alcohol and energy drink consumption on intoxication and risk-taking behavior","volume":"37","author":"Peacock","year":"2013","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.taap.2018.06.024_bb0270","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1186\/1756-0500-5-369","article-title":"Alcohol and energy drinks: a pilot study exploring patterns of consumption, social contexts, benefits and harms","volume":"5","author":"Pennay","year":"2012","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.taap.2018.06.024_bb0275","first-page":"699","article-title":"Caffeine alters oxidative homeostasis in the body of BALB\/c mice","volume":"115","author":"Pohanka","year":"2014","journal-title":"Bratisl. Lek. Listy"},{"key":"10.1016\/j.taap.2018.06.024_bb0280","first-page":"S14","article-title":"The role of NAG (N-acetyl-beta-d-glucosaminidase) in the diagnosis of kidney disease including the monitoring of nephrotoxicity","volume":"38","author":"Price","year":"1992","journal-title":"Clin. Nephrol."},{"key":"10.1016\/j.taap.2018.06.024_bb0285","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00726-004-0066-8","article-title":"Taurine restores ethanol-induced depletion of antioxidants and attenuates oxidative stress in rat tissues","volume":"27","author":"Pushpakiran","year":"2004","journal-title":"Amino Acids"},{"key":"10.1016\/j.taap.2018.06.024_bb0290","first-page":"333","article-title":"Biochemical effects of feeding soft drink and ethanol","volume":"47","author":"Raj","year":"2009","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.taap.2018.06.024_bb0295","first-page":"39","article-title":"Alcohol induced oxidative\/nitrosative stress alters brain mitochondrial membrane properties","volume":"375","author":"Reedy","year":"2013","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.taap.2018.06.024_bb0300","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1530-0277.1997.tb03816.x","article-title":"Free radical formation in livers of rats treated acutely and chronically with alcohol","volume":"21","author":"Reinke","year":"1997","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.taap.2018.06.024_bb0305","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/1750-3841.13662","article-title":"Energy drink induced lipid peroxidation and oxidative damage in rat liver and brain when used alone or combined with alcohol","volume":"82","author":"Reis","year":"2017","journal-title":"J. Food Sci."},{"key":"10.1016\/j.taap.2018.06.024_bb0310","doi-asserted-by":"crossref","first-page":"e227","DOI":"10.1542\/peds.2010-2677","article-title":"\u201cVodka energy\u201d: too much for the adolescent nephron?","volume":"128","author":"Sch\u00f6ffl","year":"2011","journal-title":"Pediatrics"},{"key":"10.1016\/j.taap.2018.06.024_bb0315","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/j.addbeh.2012.07.011","article-title":"High-risk cocktails and high-risk sex: examining the relation between alcohol mixed with energy drink consumption, sexual behavior, and drug use in college students","volume":"38","author":"Snipes","year":"2013","journal-title":"Addict. Behav."},{"key":"10.1016\/j.taap.2018.06.024_bb0320","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.drugalcdep.2016.07.016","article-title":"Alcohol mixed with energy drinks: associations with risky drinking and functioning in high school","volume":"167","author":"Tucker","year":"2016","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.taap.2018.06.024_bb0325","first-page":"69","article-title":"Biochemical effects of energy drinks alone or in combination with alcohol in normal albino rats","volume":"4","author":"Ugwuja","year":"2014","journal-title":"Adv. Pharm. Bull."},{"key":"10.1016\/j.taap.2018.06.024_bb0330","article-title":"Energy drinks and their component modulate attention, memory, and antioxidant defences in rats","author":"Valle","year":"2017","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.taap.2018.06.024_bb0335","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2147\/IJGM.S29313","article-title":"Energy drinks mixed with alcohol: misconceptions, myths, and facts","volume":"5","author":"Verster","year":"2012","journal-title":"Int. J. Gen. Med."},{"key":"10.1016\/j.taap.2018.06.024_bb0340","doi-asserted-by":"crossref","first-page":"32002","DOI":"10.1074\/jbc.M111.253344","article-title":"Taurine biosynthesis by neurons and astrocytes","volume":"286","author":"Vitvitsky","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.taap.2018.06.024_bb0345","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/MOP.0b013e3283506827","article-title":"Toxicity of energy drinks","volume":"24","author":"Wolk","year":"2012","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.taap.2018.06.024_bb0350","author":"World Health Organization in Europe"},{"key":"10.1016\/j.taap.2018.06.024_bb0355","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1007\/978-94-024-1079-2_73","article-title":"Protection of taurine against arsenic-induced DNA damage of mice kidneys","volume":"975","author":"Zheng","year":"2017","journal-title":"Adv. Exp. Med. Biol."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X18302904?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X18302904?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:47:09Z","timestamp":1758574029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X18302904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":70,"alternative-id":["S0041008X18302904"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2018.06.024","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Energy drink and alcohol combination leads to kidney and liver alterations in rats","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2018.06.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}