{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:20:24Z","timestamp":1790428824607,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.taap.2020.115304","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T12:50:54Z","timestamp":1603803054000},"page":"115304","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Prepubertal exposure to arsenic alters male reproductive parameters in pubertal and adult rats"],"prefix":"10.1016","volume":"409","author":[{"given":"Felipe","family":"Couto-Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Cl\u00e1udia Ferreira","family":"Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Silva Sena","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Ot\u00e1vio Guimar\u00e3es","family":"Ervilha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Carolina Ribeiro","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa de Sales","family":"Ara\u00fajo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone Eliza Facioni","family":"Guimar\u00e3es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro Licursi de","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Machado-Neves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2020.115304_bb0005","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/abbi.2000.2023","article-title":"Arsenic species that cause release of iron from ferritin and generation of activated oxygen","volume":"382","author":"Ahmad","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.taap.2020.115304_bb0010","first-page":"15","article-title":"Antioxidant systems and oxidative stress in the testes","volume":"1","author":"Aitken","year":"2008","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.taap.2020.115304_bb0015","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ecoenv.2015.12.044","article-title":"Human arsenic exposure via dust across the different ecological zones of Pakistan","volume":"126","author":"Alamdar","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2020.115304_bb0020","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ecoenv.2018.12.035","article-title":"Enhanced histone H3K9 tri-methylation suppresses steroidogenesis in rat testis chronically exposed to arsenic","volume":"170","author":"Alamdar","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2020.115304_bb0025","doi-asserted-by":"crossref","first-page":"774","DOI":"10.3168\/jds.S0022-0302(62)89487-9","article-title":"Reproductive capacity of daiy bulls. VIII. Direct and indirect measurement of testicular sperm production","author":"Amann","year":"1962","journal-title":"Dairy Sci."},{"key":"10.1016\/j.taap.2020.115304_bb0030","first-page":"380","article-title":"Physiology of male reproduction","volume":"57","author":"Amann","year":"1983","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.taap.2020.115304_bb0035","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.taap.2003.10.027","article-title":"A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species","volume":"198","author":"Aposhian","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115304_bb0040","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1289\/ehp.10423","article-title":"Inorganic arsenic and human prostate cancer","volume":"116","author":"Benbrahim-Tallaa","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.taap.2020.115304_bb0045","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/WOX.0b013e3182439613","article-title":"Oxidative stress and antioxidant defense","volume":"5","author":"Birben","year":"2012","journal-title":"World Allergy Organ. J."},{"key":"10.1016\/j.taap.2020.115304_bb0050","first-page":"25","article-title":"Cin\u00e9tica e quantifica\u00e7\u00e3o da espermatog\u00eanese: bases morfol\u00f3gicas e suas aplica\u00e7\u00f5es em estudos da reprodu\u00e7\u00e3o de mam\u00edferos","volume":"21","author":"Castro","year":"1997","journal-title":"Rev. Bras. Reprod. Anim."},{"key":"10.1016\/j.taap.2020.115304_bb0055","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1590\/S0102-09352004000100008","article-title":"Spermatogenesis in the collared peccary (Tayassu tajacu)","volume":"56","author":"Costa","year":"2004","journal-title":"Arq. Bras. Med. Vet. Zootec."},{"key":"10.1016\/j.taap.2020.115304_bb0060","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1080\/019262301301418865","article-title":"Pathogenesis of male reproductive toxicity","volume":"29","author":"Creasy","year":"2011","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.taap.2020.115304_bb0065","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/j.1939-4640.2001.tb02162.x","article-title":"Expression and regulation of metallothioneins in the rat epididymis","volume":"22","author":"Cyr","year":"2001","journal-title":"J. Androl."},{"key":"10.1016\/j.taap.2020.115304_bb0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/tox.22660","article-title":"Prepubertal exposure to low of sodium arsenite impairs spermatogenesis and epididymal histophysiology in rats","volume":"34","author":"Da Cunha de Medeiros","year":"2018","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.taap.2020.115304_bb0075","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.anireprosci.2007.04.002","volume":"102","author":"De Barros","year":"2007","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.taap.2020.115304_bb0080","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1210\/er.2009-0002","article-title":"Endocrine-disrupting chemicals: an Endocrine Society scientific statement","volume":"30","author":"Diamanti-Kandarakis","year":"2009","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.taap.2020.115304_bb0085","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1289\/ehp.021101147","article-title":"The concentrations of arsenic and other elements in Bangladesh\u2019s drinking water","volume":"110","author":"Frisbie","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.taap.2020.115304_bb0090","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1007\/s10661-017-6118-9","article-title":"Contamination status of arsenic in fish and shellfish from three river basins in Ghana","volume":"189","author":"Gbogbo","year":"2017","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.taap.2020.115304_bb0095","doi-asserted-by":"crossref","first-page":"18200","DOI":"10.1007\/s11356-016-6870-3","article-title":"Impact of arsenic (V) on testicular oxidative stress and sperm functional attributes in Swiss albino mice","volume":"23","author":"Guvvala","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.taap.2020.115304_bb0100","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.mrfmmm.2003.07.014","article-title":"Signaling events for metallothionein induction","volume":"533","author":"Haq","year":"2003","journal-title":"Mutat. Res."},{"key":"10.1016\/j.taap.2020.115304_bb0105","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.taap.2003.10.023","article-title":"The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds","volume":"198","author":"Hirano","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115304_bb0110","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1289\/ehp.10930","article-title":"Risk of erectile dysfunction induced by arsenic exposure through well water consumption in Taiwan","volume":"116","author":"Hsieh","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.taap.2020.115304_bb0115","doi-asserted-by":"crossref","first-page":"32518","DOI":"10.1038\/srep32518","article-title":"Integrated proteomics and metabolomics analysis of rat testis: mechanism of arsenic-induced male reproductive toxicity","volume":"6","author":"Huang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.taap.2020.115304_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-4274(02)00084-X","article-title":"Arsenic toxicity and potential mechanisms of action","volume":"133","author":"Hughes","year":"2002","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.taap.2020.115304_bb0125","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/toxsci\/kfr184","article-title":"Arsenic exposure and toxicology: a historical perspective","volume":"123","author":"Hughes","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2020.115304_bb0130","first-page":"4","article-title":"Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action","volume":"16","author":"Jana","year":"2006","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"2","key":"10.1016\/j.taap.2020.115304_bb0135","article-title":"Interpreting histopathology in the epididymis","volume":"4","author":"Kempinas","year":"2015","journal-title":"Spermatogenesis"},{"key":"10.1016\/j.taap.2020.115304_bb0140","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.reprotox.2017.07.006","article-title":"Ascorbic acid supplementation partially prevented the delayed reproductive development in juvenile male rats exposed to rosuvastatin since prepuberty","volume":"73","author":"Leite","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.taap.2020.115304_bb0145","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0076-6879(90)86141-H","article-title":"Determination of carbonyl content in oxidatively modified proteins","volume":"186","author":"Levine","year":"1990","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.taap.2020.115304_bb0150","doi-asserted-by":"crossref","first-page":"E2191","DOI":"10.3390\/ijerph15102191","article-title":"A comprehensive review of arsenic exposure and risk from rice and a risk assessment among a cohort of adolescents in Kunming, China","volume":"15","author":"Liao","year":"2018","journal-title":"Int. J. Environ. Res. Public Heath"},{"key":"10.1016\/j.taap.2020.115304_bb0155","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.reprotox.2018.04.015","article-title":"Fertility in male rats: disentangling adverse effects of arsenic compounds","volume":"78","author":"Lima","year":"2018","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.taap.2020.115304_bb0160","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.cell.2016.03.014","article-title":"On the dependency of cellular protein levels on mRNA abundance","volume":"165","author":"Liu","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.taap.2020.115304_bb0165","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.freeradbiomed.2018.03.011","article-title":"Expression of reactive species related genes is associated with patient survival in luminal B breast cancer","volume":"120","author":"Luthra","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.taap.2020.115304_bb0170","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.freeradbiomed.2009.05.018","article-title":"Regulation of superoxide dismutase genes: implications in diseases","volume":"47","author":"Miao","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.taap.2020.115304_bb0175","first-page":"1","article-title":"Orchestrating the antioxidant defenses in the epididymis","author":"O\u2019Flaherty","year":"2019","journal-title":"Andrology"},{"key":"10.1016\/j.taap.2020.115304_bb0180","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1530\/jrf.0.0990421","article-title":"Concentrations of lead, cadmium and zinc in the tissues of reproductive organs of men","volume":"99","author":"Oldereid","year":"1993","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.taap.2020.115304_bb0185","doi-asserted-by":"crossref","first-page":"5398","DOI":"10.2174\/1381612820666140205150059","article-title":"The male peripubertal phase as a developmental window for reproductive toxicology studies","volume":"20","author":"Perobelli","year":"2014","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.taap.2020.115304_bb0190","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1042\/bj2930021","article-title":"Isolation and characterization of the rat cDNA clone encoding a secreted superoxide dismutase reveals the epididymis to be a major site of its expression","volume":"293","author":"Perry","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.taap.2020.115304_bb0195","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1023\/B:BILE.0000019559.84305.47","article-title":"Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper \u2013 excel-based tool using pair-wise correlations","volume":"26","author":"Pfaffl","year":"2004","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.taap.2020.115304_bb0200","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/bdr2.1133","article-title":"Comparative aspects of pre-and postnatal development of the male reproduction system","volume":"110","author":"Picut","year":"2018","journal-title":"Births Defects Res."},{"key":"10.1016\/j.taap.2020.115304_bb0205","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1096\/fj.07-9574LSF","article-title":"Dose translation from animal to human studies revisited","volume":"22","author":"Reagan-Shaw","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.taap.2020.115304_bb0210","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jtemb.2011.08.145","article-title":"Protective effects of N-acetylcysteine against arsenic-induced oxidative stress and reprotoxicity in male mice","volume":"25","author":"Reddy","year":"2011","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.taap.2020.115304_bb0215","series-title":"Knobil and Neill\u2019s Physiology of Reproduction","first-page":"691","article-title":"The epididymis","author":"Robaire","year":"2015"},{"key":"10.1016\/j.taap.2020.115304_bb0220","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.scitotenv.2013.03.047","article-title":"Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: a systematic review and meta-analysis","volume":"454\u2013455","author":"Rodr\u00edguez-Barranco","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2020.115304_bb0225","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jes.2016.10.001","article-title":"Cellular arsenic transport pathways in mammals","volume":"49","author":"Roggenbeck","year":"2016","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.taap.2020.115304_bb0230","first-page":"1","article-title":"Role of mitochondria in the oxidative stress induced by electromagnetic fields: focus on reproductive systems","author":"Santini","year":"2018","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.taap.2020.115304_bb0235","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1530\/rep.0.1250769","article-title":"Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood","volume":"125","author":"Sharpe","year":"2003","journal-title":"Reproduction"},{"key":"10.1016\/j.taap.2020.115304_bb0240","first-page":"8843","article-title":"Urinary metabolic biomarkers link oxidative stress indicators associated with general arsenic exposure to male infertility in a han chinese population","volume":"47","author":"Shen","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.taap.2020.115304_bb0245","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/rmb2.12287","article-title":"Development of fetal and adult Leydig cells","volume":"18","author":"Shima","year":"2019","journal-title":"Reprod. Med. Biol."},{"key":"10.1016\/j.taap.2020.115304_bb0250","doi-asserted-by":"crossref","first-page":"61e7","DOI":"10.1369\/jhc.2008.952499","article-title":"Immunolocalization of aquaporin 1, 5, and 9 in the female pig reproductive system","volume":"57","author":"Skowronski","year":"2009","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.taap.2020.115304_bb0255","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s12011-015-0523-0","article-title":"Effects of sodium arsenite and arsenate in testicular histomorphometry and antioxidants enzymes activities in rats","volume":"171","author":"Souza","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"issue":"6","key":"10.1016\/j.taap.2020.115304_bb0260","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1080\/15287394.2016.1150926","article-title":"Effects of sodium arsenate and arsenite on male reproductive functions in Wistar rats","author":"Souza","year":"2016","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.taap.2020.115304_bb0265","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.lfs.2018.08.054","article-title":"Arsenic aggravates oxidative stress causing hepatic alterations and inflammation in diabetic rats","volume":"209","author":"Souza","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.taap.2020.115304_bb0270","first-page":"1","article-title":"Combined effects of arsenic exposure and diabetes on male reproductive functions","volume":"2019","author":"Souza","year":"2019","journal-title":"Andrology"},{"key":"10.1016\/j.taap.2020.115304_bb0275","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/humupd\/dmv008","article-title":"Morphological and functional maturation of Leydig cells: from rodent models to primates","volume":"21","author":"Teerds","year":"2015","journal-title":"Hum. Reprod. Update"},{"issue":"1","key":"10.1016\/j.taap.2020.115304_bb0280","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1477-7827-9-94","article-title":"In utero protein restriction causes growth delay and alters sperm parameters in adult male rats","volume":"9","author":"Toledo","year":"2011","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.taap.2020.115304_bb0285","series-title":"OCSPP Guideline 890, 1500. Standard Evaluation Procedure (SEP), Washington, DC","first-page":"1","article-title":"Pubertal development and thyroid function in intact juvenile\/peripubertal male rats assay","author":"United State Environmental Protection Agency (U.S. EPA)","year":"2011"},{"key":"10.1016\/j.taap.2020.115304_bb0290","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00204-015-1579-5","article-title":"Redox- and non-redox-metal-induced formation of free radicals and their role in human disease","volume":"90","author":"Valko","year":"2016","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.taap.2020.115304_bb0295","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1093\/humrep\/16.5.979","article-title":"Long-term effects on male reproduction of early exposure to common chemical contaminants in drinking water","volume":"16","author":"Veeramachaneni","year":"2001","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.taap.2020.115304_bb0300","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.taap.2017.11.001","article-title":"Effects of Nrf2 deficiency on arsenic metabolism in mice","volume":"337","author":"Wang","year":"2017","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115304_bb0305","series-title":"Guidelines for Drinking Water Quality","first-page":"315","author":"World Health Organization (WHO)","year":"2011"},{"key":"10.1016\/j.taap.2020.115304_bb0310","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1476-069X-11-46","article-title":"Environmental exposure to arsenic may reduce human semen quality: associations derived from a Chinese cross-sectional study","volume":"11","author":"Xu","year":"2012","journal-title":"Environ. Health"},{"key":"10.1016\/j.taap.2020.115304_bb0315","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0891-5849(02)00905-X","article-title":"Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression","volume":"33","author":"Zelko","year":"2002","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.taap.2020.115304_bb0320","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/j.1939-4640.1996.tb01823.x","article-title":"Catalase mRNA expression in the male rat reproductive tract","volume":"17","author":"Zini","year":"1996","journal-title":"J. Androl."},{"key":"10.1016\/j.taap.2020.115304_bb0325","doi-asserted-by":"crossref","first-page":"e12791","DOI":"10.1111\/and.12791","article-title":"Review on arsenic-induced toxicity in male reproductive system and its amelioration","volume":"49","author":"Zubair","year":"2017","journal-title":"Andrologia"}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X20304300?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X20304300?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:53:54Z","timestamp":1758574434000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X20304300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":65,"alternative-id":["S0041008X20304300"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2020.115304","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prepubertal exposure to arsenic alters male reproductive parameters in pubertal and adult rats","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2020.115304","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115304"}}