{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T09:40:12Z","timestamp":1778319612408,"version":"3.51.4"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":311,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003945","name":"Link\u00f6pings Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003945","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003749","name":"L\u00e4nsstyrelsen \u00d6sterg\u00f6tland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003749","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.taap.2020.115379","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T18:18:28Z","timestamp":1608833908000},"page":"115379","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury"],"prefix":"10.1016","volume":"412","author":[{"given":"Mehdi","family":"Amirhosseini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hammoudi","family":"Alkaissi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per A.","family":"Hultman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Said","family":"Havarinasab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2020.115379_bb0005","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1749-6632.1975.tb29197.x","article-title":"Immunology of DNA. III. Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique","volume":"254","author":"Aarden","year":"1975","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.taap.2020.115379_bb0010","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1365-2249.2008.03801.x","article-title":"Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?","volume":"155","author":"Abedi-Valugerdi","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0015","first-page":"355","article-title":"Gold induced thrombocytopenia: platelet associated IgG and HLA typing in three patients","volume":"11","author":"Adachi","year":"1984","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.taap.2020.115379_bb0020","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0049-0172(87)90006-0","article-title":"Gold induced thrombocytopenia - 12 cases and a review of the literature","volume":"16","author":"Adachi","year":"1987","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.taap.2020.115379_bb0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0199979","article-title":"Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development","volume":"13","author":"Alkaissi","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.taap.2020.115379_bb0030","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1177\/0748233715573691","article-title":"Low doses of mercuric chloride cause the main features of anti-nucleolar autoimmunity in female outbred CFW mice","volume":"32","author":"Arefieva","year":"2016","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.taap.2020.115379_bb0035","first-page":"405","article-title":"Urinary mercury levels in patients with autoantibodies to U3-RNP (fibrillarin)","volume":"27","author":"Arnett","year":"2000","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.taap.2020.115379_bb0040","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2018.00565","article-title":"A versatile new model of chemically induced chronic colitis using an outbred murine strain","volume":"9","author":"Barone","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.taap.2020.115379_bb0045","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1136\/ard.55.3.169","article-title":"A 10 year follow up of parenteral gold therapy in patients with rheumatoid arthritis","volume":"55","author":"Bendix","year":"1996","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.taap.2020.115379_bb0050","first-page":"358","article-title":"HLA antigens and toxic reactions to sodium Aurothiomalate in patients with rheumatoid arthritis","volume":"11","author":"Bensen","year":"1984","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.taap.2020.115379_bb0055","first-page":"753","article-title":"Metals and kidney autoimmunity","volume":"107","author":"Bigazzi","year":"1999","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.taap.2020.115379_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137647","article-title":"Recent advances in understanding and measurement of mercury in the environment: terrestrial Hg cycling","volume":"721","author":"Bishop","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2020.115379_bb0065","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jim.2012.03.001","article-title":"Optimization and diagnostic performance of a single multiparameter lineblot in the serological workup of systemic sclerosis","volume":"379","author":"Bonroy","year":"2012","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.taap.2020.115379_bb0070","first-page":"671","article-title":"Analgesic-antipyretic agents; pharmacotherapy of gout","author":"Burke","year":"2006","journal-title":"Pharmacol. Basis Therap."},{"key":"10.1016\/j.taap.2020.115379_bb0075","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0022-1759(90)90380-E","article-title":"Subnucleosome structures as substrates in enzyme-linked Immunosorbent assays","volume":"134","author":"Burlingame","year":"1990","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.taap.2020.115379_bb0080","first-page":"755","article-title":"Autoantibodies to ribonucleoprotein particles by immunoblotting, manual of clinical laboratory immunology, edited by NR Rose, ED de Macario, JL Fahey, H Friedman, GM Penn. Washington, DC","author":"Chan","year":"1992","journal-title":"Am. Soc. Med. Biol"},{"key":"10.1016\/j.taap.2020.115379_bb0085","doi-asserted-by":"crossref","first-page":"412","DOI":"10.3389\/fimmu.2015.00412","article-title":"Report of the first international consensus on standardized nomenclature of antinuclear antibody HEp-2 cell patterns 2014\u20132015","volume":"6","author":"Chan","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0090","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1038\/ng1665","article-title":"The origins and uses of mouse outbred stocks","volume":"37","author":"Chia","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.taap.2020.115379_bb0095","first-page":"258","article-title":"Chronic interstitial nephritis associated with gold therapy","volume":"107","author":"Cramer","year":"1983","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.taap.2020.115379_bb0100","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1258\/002367793780810397","article-title":"Genetic-variation within and between strains of outbred Swiss mice","volume":"27","author":"Cui","year":"1993","journal-title":"Lab. Anim."},{"key":"10.1016\/j.taap.2020.115379_bb0105","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1016\/j.febslet.2015.05.016","article-title":"A brief review of nucleosome structure","volume":"589","author":"Cutter","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.taap.2020.115379_bb0110","series-title":"Autoantibodies","first-page":"19","article-title":"Detection of autoantibodies by indirect immunofluorescence cytochemistry on hep-2 cells","author":"Dellavance","year":"2019"},{"key":"10.1016\/j.taap.2020.115379_bb0115","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.4049\/jimmunol.140.4.1022","article-title":"IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses","volume":"140","author":"Finkelman","year":"1988","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0120","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.envres.2010.02.001","article-title":"Mercury exposure, serum antinuclear\/antinucleolar antibodies, and serum cytokine levels in mining populations in Amazonian Brazil: a cross-sectional study","volume":"110","author":"Gardner","year":"2010","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2020.115379_bb0125","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1093\/rheumatology\/keq281","article-title":"Diagnostic performance and validation of autoantibody testing in myositis by a commercial line blot assay","volume":"49","author":"Ghirardello","year":"2010","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.taap.2020.115379_bb0130","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1006\/enrs.1997.3804","article-title":"Cognitive performance of children prenatally exposed to \u201csafe\u201d levels of methyl mercury","volume":"77","author":"Grandjean","year":"1998","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2020.115379_bb0135","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1111\/1756-185X.13638","article-title":"Performance evaluation of a line blot assay system for detection of anti-PM-Scl antibody in Japanese patients with systemic sclerosis","volume":"22","author":"Hamaguchi","year":"2019","journal-title":"Int. J. Rheum. Dis."},{"key":"10.1016\/j.taap.2020.115379_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408449509089885","article-title":"Minamata disease - Methyl mercury poisoning in Japan caused by environmental-pollution","volume":"25","author":"Harada","year":"1995","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.taap.2020.115379_bb0145","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.taap.2005.12.004","article-title":"Alteration of the spontaneous systemic autoimmune disease in (NZB x NZW)F1 mice by treatment with thimerosal (ethyl mercury)","volume":"214","author":"Havarinasab","year":"2006","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115379_bb0150","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.tox.2006.09.006","article-title":"Dose and hg species determine the T-helper cell activation in murine autoimmunity","volume":"229","author":"Havarinasab","year":"2007","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2020.115379_bb0155","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.taap.2007.02.009","article-title":"Mercury species in lymphoid and non-lymphoid tissues after exposure to methyl mercury: correlation with autoimmune parameters during and after treatment in susceptible mice","volume":"221","author":"Havarinasab","year":"2007","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115379_bb0160","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1365-2249.2007.03469.x","article-title":"Gold causes genetically determined autoimmune and immunostimulatory responses in mice","volume":"150","author":"Havarinasab","year":"2007","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0165","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1365-2249.2008.03831.x","article-title":"Gold- and silver-induced murine autoimmunity--requirement for cytokines and CD28 in murine heavy metal-induced autoimmunity","volume":"155","author":"Havarinasab","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0170","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1046\/j.1365-2567.1999.00671.x","article-title":"Mechanism of mercury-induced autoimmunity: both T helper 1- and T helper 2-type responses are involved","volume":"96","author":"Hu","year":"1999","journal-title":"Immunology"},{"key":"10.1016\/j.taap.2020.115379_bb0175","first-page":"269","article-title":"Mercury induced antinuclear antibodies in mice: characterization and correlation with renal immune complex deposits","volume":"71","author":"Hultman","year":"1988","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0180","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/0090-1229(92)90212-7","article-title":"Murine susceptibility to mercury. I. Autoantibody profiles and systemic immune deposits in inbred, congenic, and intra-H-2 recombinant strains","volume":"65","author":"Hultman","year":"1992","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.taap.2020.115379_bb0185","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1006\/clin.1995.1155","article-title":"Genetic susceptibility to Silver-induced anti-fibrillarin autoantibodies in mice","volume":"77","author":"Hultman","year":"1995","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.taap.2020.115379_bb0190","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.cca.2011.02.031","article-title":"Diagnostic assays for anti-PM\/Scl IgG antibodies: heterogeneity in antibody response or lack of standardization?","volume":"412","author":"Jaskowski","year":"2011","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.taap.2020.115379_bb0195","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1159\/000237619","article-title":"Murine silver-induced autoimmunity: silver shares induction of antinucleolar antibodies with mercury, but causes less activation of the immune system","volume":"113","author":"Johansson","year":"1997","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0200","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1126\/science.1948049","article-title":"Generation and analysis of interleukin-4 deficient mice","volume":"254","author":"Kuhn","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.taap.2020.115379_bb0205","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1080\/10408444.2018.1513991","article-title":"GOLD: human exposure and update on toxic risks","volume":"48","author":"Lansdown","year":"2018","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.taap.2020.115379_bb0210","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/nm.2752","article-title":"Taming lupus-a new understanding of pathogenesis is leading to clinical advances","volume":"18","author":"Liu","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.taap.2020.115379_bb0215","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2017.01527","article-title":"Revealing the complexity in CD8 T cell responses to infection in inbred C57B\/6 versus outbred Swiss mice","volume":"8","author":"Martin","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0220","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.00874","article-title":"Silicosis and silica-induced autoimmunity in the diversity outbred mouse","volume":"9","author":"Mayeux","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0225","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/368274","article-title":"The spectrum of anti-chromatin\/nucleosome autoantibodies: independent and interdependent biomarkers of disease","volume":"2014","author":"Mehra","year":"2014","journal-title":"J Immunol Res"},{"key":"10.1016\/j.taap.2020.115379_bb0230","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.3899\/jrheum.090207","article-title":"Systemic sclerosis: environmental factors","volume":"36","author":"Mora","year":"2009","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.taap.2020.115379_bb0235","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.envres.2014.03.024","article-title":"Novel biomarkers of mercury-induced autoimmune dysfunction: a cross-sectional study in Amazonian Brazil","volume":"132","author":"Motts","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2020.115379_bb0240","author":"N.I.H"},{"key":"10.1016\/j.taap.2020.115379_bb0245","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000234999","article-title":"Immunological alterations inducible by mercury-compounds .2. Hgcl2 and gold sodium Thiomalate enhance serum Ige and serum igg concentrations in susceptible mouse strains","volume":"90","author":"Pietsch","year":"1989","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0250","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1111\/j.1468-3083.2006.02107.x","article-title":"Linking allergy to mercury to HLA and burning mouth syndrome","volume":"21","author":"Pigatto","year":"2007","journal-title":"J. Eur. Acad. Dermatol."},{"key":"10.1016\/j.taap.2020.115379_bb0255","series-title":"Autoantibodies","first-page":"319","article-title":"Fibrillarin autoantibodies","author":"Pollard","year":"2014"},{"key":"10.1016\/j.taap.2020.115379_bb0260","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.4049\/jimmunol.158.7.3521","article-title":"The autoimmunity-inducing xenobiotic mercury interacts with the autoantigen fibrillarin and modifies its molecular and antigenic properties","volume":"158","author":"Pollard","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0265","doi-asserted-by":"crossref","first-page":"129299","DOI":"10.1016\/j.bbagen.2019.02.001","article-title":"Mercury-induced inflammation and autoimmunity","volume":"1863","author":"Pollard","year":"2019","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"10.1016\/j.taap.2020.115379_bb0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12882-019-1413-z","article-title":"Mercury-associated glomerulonephritis: a retrospective study of 35 cases in a single Chinese center","volume":"20","author":"Qin","year":"2019","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.taap.2020.115379_bb0275","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1073\/pnas.86.1.237","article-title":"Mercuric-chloride induces autoantibodies against U3 small nuclear ribonucleoprotein in susceptible mice","volume":"86","author":"Reuter","year":"1989","journal-title":"P. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.taap.2020.115379_bb0280","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/283157a0","article-title":"Genetic variance of laboratory outbred Swiss mice","volume":"283","author":"Rice","year":"1980","journal-title":"Nature"},{"key":"10.1016\/j.taap.2020.115379_bb0285","first-page":"300","article-title":"Induction of anti-nuclear antibodies by mercuric-chloride in mice","volume":"58","author":"Robinson","year":"1984","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0290","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0041-008X(86)90046-3","article-title":"Mercuric chloride-induced, gold sodium Thiomalate-induced, and D-Penicillamine-induced antinuclear antibodies in mice","volume":"86","author":"Robinson","year":"1986","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115379_bb0295","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1006\/clin.1997.4336","article-title":"Murine strain differences in response to mercuric chloride: antinucleolar antibodies production does not correlate with renal immune complex deposition","volume":"83","author":"Robinson","year":"1997","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.taap.2020.115379_bb0300","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1136\/ard.52.4.300","article-title":"Gold induced nephropathy in rheumatoid-arthritis and Hla class-ii genes","volume":"52","author":"Sakkas","year":"1993","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.taap.2020.115379_bb0305","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.scitotenv.2014.05.003","article-title":"An estimation of the artisanal small-scale production of gold in the world","volume":"496","author":"Seccatore","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2020.115379_bb0310","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.3899\/jrheum.110071","article-title":"Anti-Fibrillarin antibody in African American patients with systemic sclerosis: immunogenetics, clinical features, and survival analysis","volume":"38","author":"Sharif","year":"2011","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.taap.2020.115379_bb0315","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/ard.51.1.23","article-title":"HLA-D region genes and rheumatoid-arthritis (RA) - importance of DR and DQ genes in conferring susceptibility to RA","volume":"51","author":"Singal","year":"1992","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.taap.2020.115379_bb0320","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1476-069X-13-111","article-title":"The burden of chronic mercury intoxication in artisanal small-scale gold mining in Zimbabwe: data availability and preliminary estimates","volume":"13","author":"Steckling","year":"2014","journal-title":"Environ. Health"},{"key":"10.1016\/j.taap.2020.115379_bb0325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207587","article-title":"Evaluation of an outbred mouse model for Francisella tularensis vaccine development and testing","volume":"13","author":"Sunagar","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.taap.2020.115379_bb0330","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1093\/labmed\/lmy024","article-title":"Antinuclear antibodies: marker of diagnosis and evolution in autoimmune diseases","volume":"49","author":"Sur","year":"2018","journal-title":"Lab. Med."},{"key":"10.1016\/j.taap.2020.115379_bb0335","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1038\/ni.3731","article-title":"The multiple pathways to autoimmunity","volume":"18","author":"Theofilopoulos","year":"2017","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0340","series-title":"United Nations Environment Programme DTIE Chemicals Branch and WHO Department of Food Safety Zoonoses and Foodborne Diseases","article-title":"Guidance for identifying populations at risk from mercury exposure","author":"UNEP","year":"2008"},{"key":"10.1016\/j.taap.2020.115379_bb0345","first-page":"240","article-title":"2008. Immunology of mercury","volume":"1143","author":"Vas","year":"2008","journal-title":"Year Immunol."},{"key":"10.1016\/j.taap.2020.115379_bb0350","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1006\/taap.1995.1111","article-title":"Systemic autoimmunity due to mercury-vapor exposure in genetically susceptible mice - dose-response studies","volume":"132","author":"Warfvinge","year":"1995","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2020.115379_bb0355","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1056\/NEJM198008073030602","article-title":"Hla-Dr antigens and toxic reaction to sodium aurothiomalate and D-Penicillamine in patients with rheumatoid-arthritis","volume":"303","author":"Wooley","year":"1980","journal-title":"New. Engl. J. Med."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X20305019?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X20305019?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:54:09Z","timestamp":1758574449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X20305019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":71,"alternative-id":["S0041008X20305019"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2020.115379","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2020.115379","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115379"}}