{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T18:46:36Z","timestamp":1792349196301,"version":"4.4.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004000","name":"Guangzhou Science and Technology Program key projects","doi-asserted-by":"publisher","award":["104267472039"],"award-info":[{"award-number":["104267472039"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Science and Technology Program key projects","doi-asserted-by":"publisher","award":["201904010161"],"award-info":[{"award-number":["201904010161"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020084","name":"Guangzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020084","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31500076"],"award-info":[{"award-number":["31500076"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173476"],"award-info":[{"award-number":["82173476"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.taap.2022.116194","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T11:07:20Z","timestamp":1660043240000},"page":"116194","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["The disruption on gut microbiome of Decabromodiphenyl ethane exposure in the simulator of the human intestinal microbial ecosystem (SHIME)"],"prefix":"10.1016","volume":"452","author":[{"given":"Fengmin","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiguo","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoxia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2022.116194_bb0005","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13024-021-00427-6","article-title":"Relationships of gut microbiota, short-chain fatty acids, inflammation, and the gut barrier in Parkinson\u2019s disease","volume":"16","author":"Aho","year":"2021","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.taap.2022.116194_bb0010","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12974-019-1494-4","article-title":"Antibiotics, gut microbiota, and Alzheimer\u2019s disease","volume":"16","author":"Angelucci","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.taap.2022.116194_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105179","article-title":"Thyroid function and decabromodiphenyl ethane (DBDPE) exposure in Chinese adults from a DBDPE manufacturing area","volume":"133","author":"Chen","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2022.116194_bb0020","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.canlet.2019.11.019","article-title":"Clostridium butyricum, a butyrate-producing probiotic, inhibits intestinal tumor development through modulating Wnt signaling and gut microbiota","volume":"469","author":"Chen","year":"2020","journal-title":"Cancer Lett."},{"key":"10.1016\/j.taap.2022.116194_bb0025","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.envres.2018.10.010","article-title":"Occurrence of flame retardants in landfills: a case study in Brazil","volume":"168","author":"Cristale","year":"2019","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2022.116194_bb0030","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S1474-4422(19)30356-4","article-title":"The gut microbiome in neurological disorders","volume":"19","author":"Cryan","year":"2020","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.taap.2022.116194_bb0035","doi-asserted-by":"crossref","first-page":"4050","DOI":"10.1172\/JCI129194","article-title":"The gut microbiome and metabolic syndrome","volume":"129","author":"Dabke","year":"2019","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.taap.2022.116194_bb0040","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S1001-0742(11)60801-2","article-title":"Concentrations and sources of an emerging pollutant, decabromodiphenyl ethane (DBDPE), in sewage sludge for land application","volume":"24","author":"De la Torre","year":"2012","journal-title":"J. Environ. Sci. (China)"},{"key":"10.1016\/j.taap.2022.116194_bb0045","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1080\/19490976.2020.1737307","article-title":"Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice","volume":"11","author":"Depommier","year":"2020","journal-title":"Gut Microbes"},{"key":"10.1016\/j.taap.2022.116194_bb0050","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.24333","article-title":"Alterations of gut microbiota-derived metabolites in gestational diabetes mellitus and clinical significance","author":"Gao","year":"2022","journal-title":"J. Clin. Lab. Anal."},{"key":"10.1016\/j.taap.2022.116194_bb0055","first-page":"308","article-title":"The human gut microbiota: metabolism and perspective in obesity","volume":"9","author":"Gomes","year":"2018","journal-title":"Gut Microbes"},{"key":"10.1016\/j.taap.2022.116194_bb0060","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1007\/s00394-020-02414-x","article-title":"Inulin supplementation ameliorates hyperuricemia and modulates gut microbiota in Uox-knockout mice","volume":"60","author":"Guo","year":"2021","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.taap.2022.116194_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118060","article-title":"Environmental occurrence and remediation of emerging organohalides: a review","volume":"290","author":"He","year":"2021","journal-title":"Environ Pollut. (Barking, Essex: 1987)"},{"key":"10.1016\/j.taap.2022.116194_bb0070","article-title":"High-amylose corn starch regulated gut microbiota and serum bile acids in high-fat diet-induced obese mice","volume":"23","author":"Hu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.taap.2022.116194_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114844","article-title":"Effects of difenoconazole on hepatotoxicity, lipid metabolism and gut microbiota in zebrafish (Danio rerio)","volume":"265","author":"Jiang","year":"2020","journal-title":"Environ Pollut. (Barking, Essex: 1987)"},{"key":"10.1016\/j.taap.2022.116194_bb0080","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.chemosphere.2019.02.115","article-title":"Cardiovascular toxicity of decabrominated diphenyl ethers (BDE-209) and decabromodiphenyl ethane (DBDPE) in rats","volume":"223","author":"Jing","year":"2019","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131550","article-title":"Oxidative stress and endoplasmic reticulum stress contributed to hepatotoxicity of decabromodiphenyl ethane (DBDPE) in L-02 cells","volume":"286","author":"Jing","year":"2022","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0090","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2016.05.041","article-title":"From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites","volume":"165","author":"Koh","year":"2016","journal-title":"Cell."},{"key":"10.1016\/j.taap.2022.116194_bb0095","doi-asserted-by":"crossref","DOI":"10.1126\/science.aag2770","article-title":"Chemical transformation of xenobiotics by the human gut microbiota","volume":"356","author":"Koppel","year":"2017","journal-title":"Science."},{"key":"10.1016\/j.taap.2022.116194_bb0100","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.taap.2016.05.016","article-title":"TCDD modulation of gut microbiome correlated with liver and immune toxicity in streptozotocin (STZ)-induced hyperglycemic mice","volume":"304","author":"Lefever","year":"2016","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2022.116194_bb0105","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1124\/dmd.118.081547","article-title":"PBDEs altered gut microbiome and bile acid homeostasis in male C57BL\/6 mice","volume":"46","author":"Li","year":"2018","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.taap.2022.116194_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125492","article-title":"Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice","volume":"244","author":"Li","year":"2020","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141415","article-title":"Colistin and amoxicillin combinatorial exposure alters the human intestinal microbiota and antibiotic resistome in the simulated human intestinal microbiota","volume":"750","author":"Li","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2022.116194_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106307","article-title":"BDE-209 and DBDPE induce male reproductive toxicity through telomere-related cell senescence and apoptosis in SD rat","volume":"146","author":"Li","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2022.116194_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148744","article-title":"Characteristics of legacy and novel brominated flame retardants in water and sediment surrounding two e-waste dismantling regions in Taizhou, eastern China","volume":"794","author":"Ling","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2022.116194_bb0130","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.chemosphere.2018.10.140","article-title":"Exploring the membrane toxicity of decabromodiphenyl ethane (DBDPE): based on cell membranes and lipid membranes model","volume":"216","author":"Liu","year":"2019","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.109004","article-title":"Perinatal Triclosan exposure in the rat induces long-term disturbances in metabolism and gut microbiota in adulthood and old age","volume":"182","author":"Ma","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2022.116194_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpharm.2018.11.020","article-title":"A four-strain probiotic exerts positive immunomodulatory effects by enhancing colonic butyrate production in vitro","volume":"555","author":"Moens","year":"2019","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.taap.2022.116194_bb0145","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1007\/s00394-019-02050-0","article-title":"Influence of a 3-month low-calorie Mediterranean diet compared to the vegetarian diet on human gut microbiota and SCFA: the CARDIVEG study","volume":"59","author":"Pagliai","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.taap.2022.116194_bb0150","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.scitotenv.2019.01.245","article-title":"Microplastics induce intestinal inflammation, oxidative stress, and disorders of metabolome and microbiome in zebrafish","volume":"662","author":"Qiao","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2022.116194_bb0155","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/1462-2920.13463","article-title":"Pediatric obesity is associated with an altered gut microbiota and discordant shifts in Firmicutes populations","volume":"19","author":"Riva","year":"2017","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.taap.2022.116194_bb0160","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22179549","article-title":"Relationships of gut microbiota composition, short-chain fatty acids and polyamines with the pathological response to neoadjuvant radiochemotherapy in colorectal cancer patients","volume":"22","author":"S\u00e1nchez-Alcoholado","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.taap.2022.116194_bb0165","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/s41579-019-0213-6","article-title":"Microbial genes and pathways in inflammatory bowel disease","volume":"17","author":"Schirmer","year":"2019","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.taap.2022.116194_bb0170","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.envpol.2019.03.090","article-title":"Stocks, flows and emissions of DBDPE in China and its international distribution through products and waste","volume":"250","author":"Shen","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.taap.2022.116194_bb0175","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202002585R","article-title":"Decabromodiphenyl ethane exposure damaged the asymmetric division of mouse oocytes by inhibiting the inactivation of cyclin-dependent kinase 1","volume":"35","author":"Shi","year":"2021","journal-title":"FASEB J."},{"key":"10.1016\/j.taap.2022.116194_bb0180","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.tibtech.2015.06.011","article-title":"Proteobacteria: microbial signature of dysbiosis in gut microbiota","volume":"33","author":"Shin","year":"2015","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.taap.2022.116194_bb0185","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3389\/fendo.2020.00025","article-title":"The role of short-chain fatty acids from gut microbiota in gut-brain communication","volume":"11","author":"Silva","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.taap.2022.116194_bb0190","doi-asserted-by":"crossref","DOI":"10.3390\/nu12092808","article-title":"Effects of human milk oligosaccharides on the adult gut microbiota and barrier function","volume":"12","author":"\u0160uligoj","year":"2020","journal-title":"Nutrients."},{"key":"10.1016\/j.taap.2022.116194_bb0195","first-page":"12","article-title":"Endocrine disruption activity of 30-day dietary exposure to decabromodiphenyl ethane in Balb\/C mouse","volume":"31","author":"Sun","year":"2018","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.taap.2022.116194_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135783","article-title":"Hepatotoxicity of decabromodiphenyl ethane (DBDPE) and decabromodiphenyl ether (BDE-209) in 28-day exposed Sprague-Dawley rats","volume":"705","author":"Sun","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2022.116194_bb0205","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1021\/acs.est.1c06679","article-title":"Decabromodiphenyl ethane mainly affected the muscle contraction and reproductive endocrine system in female adult zebrafish","volume":"56","author":"Sun","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.taap.2022.116194_bb0210","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jhazmat.2018.05.011","article-title":"Influence of gastrointestinal tract on metabolism of bisphenol a as determined by in vitro simulated system","volume":"355","author":"Wang","year":"2018","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.taap.2022.116194_bb0215","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12989-018-0252-6","article-title":"Exposure to concentrated ambient PM (2.5) alters the composition of gut microbiota in a murine model","volume":"15","author":"Wang","year":"2018","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.taap.2022.116194_bb0220","doi-asserted-by":"crossref","first-page":"8437","DOI":"10.1021\/acs.est.9b02831","article-title":"Bioconcentration, biotransformation, and thyroid endocrine disruption of decabromodiphenyl ethane (Dbdpe), a novel brominated flame retardant, in zebrafish larvae","volume":"53","author":"Wang","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.taap.2022.116194_bb0225","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ecoenv.2019.02.080","article-title":"A comparison of the thyroid disruption induced by deca brominated diphenyl ethers (BDE-209) and decabromodiphenyl ethane (DBDPE) in rats","volume":"174","author":"Wang","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2022.116194_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.126843","article-title":"Dietary exposure assessment of a nursing mother-infant cohort to legacy and novel brominated flame retardants: results of a 3-day duplicate diet study in Beijing, China","volume":"254","author":"Wang","year":"2020","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127443","article-title":"Comparison of bioaccessibility and relative bioavailability of arsenic in rice bran: the in vitro with PBET\/SHIME and in vivo with mice model","volume":"259","author":"Wang","year":"2020","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fsi.2022.02.050","article-title":"Acute effects of antimony exposure on adult zebrafish (Danio rerio): from an oxidative stress and intestinal microbiota perspective","volume":"123","author":"Wang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.taap.2022.116194_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibiod.2021.105255","article-title":"Dechlorane plus exposure on gut microbiome evaluated by using both in vivo and in vitro assays","volume":"163","author":"Wu","year":"2021","journal-title":"Int. Biodeterior. Biodegrad."},{"key":"10.1016\/j.taap.2022.116194_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127067","article-title":"Low-concentration of dichloroacetonitrile (DCAN) in drinking water perturbs the health-associated gut microbiome and metabolic profile in rats","volume":"258","author":"Xue","year":"2020","journal-title":"Chemosphere."},{"key":"10.1016\/j.taap.2022.116194_bb0255","doi-asserted-by":"crossref","first-page":"17578","DOI":"10.1038\/s41598-017-17901-1","article-title":"Investigation of bioaccessibility of Cu, Fe, Mn, and Zn in market vegetables in the colon using PBET combined with SHIME","volume":"7","author":"Yin","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.taap.2022.116194_bb0260","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.envres.2019.01.028","article-title":"Halogenated organic pollutants in sediments and organisms from mangrove wetlands of the Jiulong River Estuary, South China","volume":"171","author":"Zhang","year":"2019","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2022.116194_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2020.111733","article-title":"Polybrominated diphenyl ethers, decabromodiphenyl ethane and dechlorane plus in aquatic products from the Yellow River Delta, China","volume":"161","author":"Zhang","year":"2020","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.taap.2022.116194_bb0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105770","article-title":"Intergenerational transfer of Dechlorane plus and the associated long-term effects on the structure and function of gut microbiota in offspring","volume":"141","author":"Zhang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2022.116194_bb0275","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.scitotenv.2014.10.076","article-title":"Contaminant sources, gastrointestinal absorption, and tissue distribution of organohalogenated pollutants in chicken from an e-waste site","volume":"505","author":"Zheng","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2022.116194_bb0280","article-title":"Low dose of sucralose alter gut microbiome in mice","volume":"9","author":"Zheng","year":"2022","journal-title":"Front. Nutrit."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X22003398?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X22003398?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:59:17Z","timestamp":1758574757000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X22003398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":56,"alternative-id":["S0041008X22003398"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2022.116194","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The disruption on gut microbiome of Decabromodiphenyl ethane exposure in the simulator of the human intestinal microbial ecosystem (SHIME)","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2022.116194","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116194"}}