{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T22:13:07Z","timestamp":1783548787679,"version":"3.55.0"},"reference-count":85,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012669","name":"Natural Science Foundation Project of Chongqing","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21403021"],"award-info":[{"award-number":["21403021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing","doi-asserted-by":"publisher","award":["CSTB2023NSCQ-MSX0128"],"award-info":[{"award-number":["CSTB2023NSCQ-MSX0128"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing","doi-asserted-by":"publisher","award":["cstc2019jcyj-msxmX0177"],"award-info":[{"award-number":["cstc2019jcyj-msxmX0177"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.taap.2023.116629","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T11:10:15Z","timestamp":1689592215000},"page":"116629","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Reproductive effects of pubertal exposure to neonicotinoid thiacloprid in immature male mice"],"prefix":"10.1016","volume":"474","author":[{"given":"Yong","family":"Zou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohua","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengzhi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jieying","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2023.116629_bb0005","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.fertnstert.2005.12.070","article-title":"Testicular expression of synaptonemal complex protein 3 (SYCP3) messenger ribonucleic acid in 110 patients with nonobstructive azoospermia","volume":"86","author":"Aarabi","year":"2006","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.taap.2023.116629_bb0010","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S1385-299X(96)00036-0","article-title":"Male rat sexual behavior","volume":"1","author":"Agmo","year":"1997","journal-title":"Brain Res. Brain Res. Protoc."},{"key":"10.1016\/j.taap.2023.116629_bb0015","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3109\/15376516.2015.1045663","article-title":"Recovery by N-acetylcysteine from subchronic exposure to imidacloprid- induced hypothalamic-pituitary-adrenal (HPA) axis tissues injury in male rats","volume":"25","author":"Annabi","year":"2015","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.taap.2023.116629_bb0020","doi-asserted-by":"crossref","first-page":"8985","DOI":"10.1038\/s41598-020-65887-0","article-title":"Reproductive effects of subchronic exposure to acetamiprid in male rats","volume":"10","author":"Ar\u0131can","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.taap.2023.116629_bb0025","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/toxsci\/kfy172","article-title":"m6A demethylase FTO regulates dopaminergic neurotransmission deficits caused by arsenite","volume":"165","author":"Bai","year":"2018","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2023.116629_bb0030","doi-asserted-by":"crossref","first-page":"R772","DOI":"10.1016\/j.cub.2018.05.061","article-title":"Neonicotinoids","volume":"28","author":"Bass","year":"2018","journal-title":"Curr. Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0035","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.pestbp.2015.04.004","article-title":"The global status of insect resistance to neonicotinoid insecticides","volume":"121","author":"Bass","year":"2015","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.taap.2023.116629_bb0040","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s11356-014-3332-7","article-title":"Environmental fate and exposure; neonicotinoids and fipronil","volume":"22","author":"Bonmatin","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0045","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqaa137","article-title":"Brain aromatase and the regulation of sexual activity in male mice","volume":"161","author":"Brooks","year":"2020","journal-title":"Endocrinology"},{"key":"10.1016\/j.taap.2023.116629_bb0050","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.taap.2017.07.018","article-title":"The use of a unique co-culture model of fetoplacental steroidogenesis as a screening tool for endocrine disruptors: the effects of neonicotinoids on aromatase activity and hormone production","volume":"332","author":"Caron-Beaudoin","year":"2017","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2023.116629_bb0055","article-title":"A rare presentation of imidacloprid poisoning","volume":"15","author":"Chadalavada","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.taap.2023.116629_bb0060","doi-asserted-by":"crossref","first-page":"6082","DOI":"10.1021\/jf501397m","article-title":"Quantitative analysis of neonicotinoid insecticide residues in foods: implication for dietary exposures","volume":"62","author":"Chen","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.taap.2023.116629_bb0065","first-page":"20110338","article-title":"piRNA and spermatogenesis in mice","volume":"368","author":"Chuma","year":"2013","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"key":"10.1016\/j.taap.2023.116629_bb0070","first-page":"5178","article-title":"Conclusion on the peer review of the pesticide risk assessment for bees for the active substance imidacloprid considering the uses as seed treatments and granules","volume":"16","author":"EFSA (European Food Safety Authority)","year":"2018","journal-title":"EFSA J."},{"key":"10.1016\/j.taap.2023.116629_bb0075","first-page":"5179","article-title":"Conclusions on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam considering the uses as seed treatments and granules","volume":"16","author":"EFSA (European Food Safety Authority)","year":"2018","journal-title":"EFSA J."},{"key":"10.1016\/j.taap.2023.116629_bb0080","first-page":"5177","article-title":"Conclusions on the peer review of the pesticide risk assessment for bees for the active substance clothianidin considering the uses as seed treatments and granules","volume":"16","author":"EFSA (European Food Safety Authority)","year":"2018","journal-title":"EFSA J."},{"key":"10.1016\/j.taap.2023.116629_bb0085","first-page":"5595","article-title":"Conclusion on the peer review of the pesticide risk assessment of the active substance thiacloprid","volume":"17","author":"EFSA (European Food Safety Authority)","year":"2019","journal-title":"EFSA J."},{"key":"10.1016\/j.taap.2023.116629_bb0090","first-page":"3132","volume":"11","author":"EFSA Scientific Committee","year":"2013","journal-title":"EFSA J."},{"key":"10.1016\/j.taap.2023.116629_bb0095","series-title":"StatPearls [Internet]. Treasure Island (FL)","article-title":"Tanner stages","author":"Emmanuel","year":"2021"},{"key":"10.1016\/j.taap.2023.116629_bb0100","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1083\/jcb.201710078","article-title":"Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells","volume":"217","author":"Gao","year":"2018","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0105","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.chemosphere.2017.10.149","article-title":"Human exposure to neonicotinoid insecticides and the evaluation of their potential toxicity: an overview","volume":"192","author":"Han","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.taap.2023.116629_bb0110","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.691060","article-title":"Epigenetic effects promoted by neonicotinoid thiacloprid exposure","volume":"9","author":"Hartman","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0115","doi-asserted-by":"crossref","first-page":"3222","DOI":"10.3390\/ijerph17093222","article-title":"An overview on the effect of neonicotinoid insecticides on mammalian cholinergic functions through the activation of neuronal nicotinic acetylcholine receptors","volume":"17","author":"Houchat","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.taap.2023.116629_bb0120","series-title":"Test Method for Mutagenic, Teratogenic and Carcinogenic of Environmental Chemicals","author":"Huang","year":"1985"},{"key":"10.1016\/j.taap.2023.116629_bb0125","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1080\/15548627.2020.1783822","article-title":"Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice","volume":"17","author":"Huang","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2023.116629_bb0130","series-title":"Rats Sperm Morphological Assessment Guideline Document","first-page":"1","author":"IRDG (Industrial Reproductive Toxicology Discussion Group)., CASA (Computer Assisted Sperm Analysis) Group","year":"2000"},{"key":"10.1016\/j.taap.2023.116629_bb0135","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1021\/jf101303g","article-title":"Overview of the status and global strategy for neonicotinoids","volume":"59","author":"Jeschke","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.taap.2023.116629_bb0140","first-page":"553","article-title":"Assessment of toxicological effects of mancozeb in male rats after chronic exposure","volume":"37","author":"Kackar","year":"1999","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0145","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1080\/13813455.2017.1347686","article-title":"Potential protective effects of polysaccharide extracted from Ulva lactuca against male reprotoxicity induced by thiacloprid","volume":"123","author":"Kammoun","year":"2017","journal-title":"Arch. Physiol. Biochem."},{"key":"10.1016\/j.taap.2023.116629_bb0150","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1016\/j.fct.2011.09.009","article-title":"Toxicological impact of technical imidacloprid on ovarian morphology, hormones and antioxidant enzymes in female rats","volume":"49","author":"Kapoor","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.taap.2023.116629_bb0155","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1300\/J069v18n03_04","article-title":"Periadolescent nicotine exposure reduces cocaine reward in adult mice","volume":"18","author":"Kelley","year":"1999","journal-title":"J. Addict. Dis."},{"key":"10.1016\/j.taap.2023.116629_bb0160","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1292\/jvms.21-0014","article-title":"Effects of in utero and lactational exposure to the no-observed-adverse-effect level (NOAEL) dose of the neonicotinoid clothianidin on the reproductive organs of female mice","volume":"83","author":"Kitauchi","year":"2021","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.taap.2023.116629_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113727","article-title":"Neonicotinoids: a critical assessment of the global research landscape of the most extensively used insecticide","volume":"213","author":"Klingelh\u00f6fer","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0170","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/MED.0000000000000339","article-title":"Testicular growth and development in puberty","volume":"24","author":"Koskenniemi","year":"2017","journal-title":"Curr. Opin. Endocrinol. Diabetes Obes."},{"key":"10.1016\/j.taap.2023.116629_bb0175","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1530\/jrf.0.0620385","article-title":"Sperm head abnormalities in relation to the age and strain of mice","volume":"62","author":"Krzanowska","year":"1981","journal-title":"J. Reprod. Fertil."},{"issue":"456","key":"10.1016\/j.taap.2023.116629_bb0180","article-title":"Sex-specific behavioral effects of acute exposure to the neonicotinoid clothianidin in mice","volume":"2022","author":"Kubo","year":"2022","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.taap.2023.116629_bb0185","doi-asserted-by":"crossref","first-page":"55336","DOI":"10.1007\/s11356-022-21226-6","article-title":"A review of spatiotemporal patterns of neonicotinoid insecticides in water, sediment, and soil across China","volume":"29","author":"Liu","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0190","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.taap.2023.116629_bb0195","first-page":"779","article-title":"A case of acute poisoning with thiamethoxam","volume":"40","author":"Lou","year":"2022","journal-title":"Chin. J. Ind. Hyg. Occup. Dis."},{"key":"10.1016\/j.taap.2023.116629_bb0200","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1021\/acs.est.7b05596","article-title":"Neonicotinoid residues in fruits and vegetables: an integrated dietary exposure assessment approach","volume":"52","author":"Lu","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.taap.2023.116629_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.134726","article-title":"Triphenyltin disrupts the testicular microenvironment and reduces sperm quality in adult male rats","volume":"301","author":"Lu","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.taap.2023.116629_bb0210","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10863-014-9592-6","article-title":"Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function","volume":"48","author":"Martin","year":"2016","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.taap.2023.116629_bb0215","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.jsps.2022.06.016","article-title":"Origanum majorana essential oil improves the rat's sexual behavior and testicular oxidative damage induced by imidacloprid via modulating the steroidogenesis pathways","volume":"9","author":"Mehanna","year":"2022","journal-title":"Saudi Pharm. J."},{"key":"10.1016\/j.taap.2023.116629_bb0220","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.tem.2017.09.002","article-title":"Steroidogenesis: unanswered questions","volume":"28","author":"Miller","year":"2017","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.taap.2023.116629_bb0225","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.envint.2014.10.024","article-title":"Neonicotinoid contamination of global surface waters and associated risk to aquatic invertebrates: a review","volume":"74","author":"Morrissey","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2023.116629_bb0230","doi-asserted-by":"crossref","first-page":"786","DOI":"10.4103\/ijccm.IJCCM_152_17","article-title":"Imidacloprid poisoning: an emerging cause of potentially fatal poisoning","volume":"21","author":"Mundhe","year":"2017","journal-title":"Indian J. Crit. Care Med."},{"key":"10.1016\/j.taap.2023.116629_bb0235","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/380159a0","article-title":"Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice","volume":"380","author":"Nantel","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.taap.2023.116629_bb0240","author":"NCBI (National Center for Biotechnology Information)"},{"key":"10.1016\/j.taap.2023.116629_bb0245","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.semcdb.2016.04.009","article-title":"Spermatogenesis in humans and its affecting factors","volume":"59","author":"Neto","year":"2016","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0250","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.3928\/19382359-20171214-04","article-title":"Premature adrenarche","volume":"47","author":"Novello","year":"2018","journal-title":"Pediatr. Ann."},{"key":"10.1016\/j.taap.2023.116629_bb0255","article-title":"Mechanisms of spermiogenesis and spermiation and how they are disturbed","volume":"4","author":"O'Donnell","year":"2014","journal-title":"Spermatogenesis"},{"key":"10.1016\/j.taap.2023.116629_bb0260","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1080\/10253890.2017.1369523","article-title":"Hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes: sex differences in regulation of stress responsivity","volume":"20","author":"Oyola","year":"2017","journal-title":"Stress"},{"key":"10.1016\/j.taap.2023.116629_bb0265","doi-asserted-by":"crossref","first-page":"5106","DOI":"10.3390\/ijms22105106","article-title":"Partial agonist activity of neonicotinoids on rat nicotinic receptors: consequences over epinephrine secretion and in vivo blood pressure","volume":"22","author":"Park","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.taap.2023.116629_bb0270","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1093\/ajhp\/57.22.2048","article-title":"DHEA: dehydroepiandrosterone","volume":"57","author":"Pepping","year":"2000","journal-title":"Am. J. Health Syst. Pharm."},{"key":"10.1016\/j.taap.2023.116629_bb0275","article-title":"Acute poisoning with acetamiprid, a type of neonicotinoid insecticide causing severe lactic acidosis: a case report","volume":"9","author":"Pravinson","year":"2021","journal-title":"SAGE Open Med. Case Rep."},{"key":"10.1016\/j.taap.2023.116629_bb0280","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1529-8019.2008.00214.x","article-title":"Androgens and hair growth","volume":"21","author":"Randall","year":"2008","journal-title":"Dermatol. Ther."},{"key":"10.1016\/j.taap.2023.116629_bb0285","doi-asserted-by":"crossref","first-page":"39206","DOI":"10.1074\/jbc.M104724200","article-title":"Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3","volume":"276","author":"Sampson","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.taap.2023.116629_bb0290","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1158\/0008-5472.CAN-16-0707","article-title":"Cell-cycle regulation accounts for variability in Ki-67 expression levels","volume":"77","author":"Sobecki","year":"2017","journal-title":"Cancer Res."},{"key":"10.1016\/j.taap.2023.116629_bb0295","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jsbmb.2008.03.004","article-title":"Hormonal regulation of spermatogenesis and spermiogenesis","volume":"109","author":"Sofikitis","year":"2008","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0300","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1101\/gad.14.7.841","article-title":"The mouse homolog of Drosophila vasa is required for the development of male germ cells","volume":"14","author":"Tanaka","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.taap.2023.116629_bb0305","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuro.2018.04.012","article-title":"Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure","volume":"67","author":"Tang","year":"2018","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.taap.2023.116629_bb0310","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1080\/09603123.2018.1504897","article-title":"Effect of acetamiprid on the immature murine testes","volume":"28","author":"Terayama","year":"2018","journal-title":"Int. J. Environ. Health Res."},{"key":"10.1016\/j.taap.2023.116629_bb0315","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1039\/C9EM00586B","article-title":"A critical review on the potential impacts of neonicotinoid insecticide use: current knowledge of environmental fate, toxicity, and implications for human health","volume":"22","author":"Thompson","year":"2020","journal-title":"Environ Sci Process Impacts"},{"key":"10.1016\/j.taap.2023.116629_bb0320","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1002\/j.2040-4603.2014.tb00590.x","article-title":"Adrenal androgens and androgen precursors-definition, synthesis, regulation and physiologic actions","volume":"4","author":"Turcu","year":"2014","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.taap.2023.116629_bb0325","author":"U.S. Environmental Protection Agency"},{"key":"10.1016\/j.taap.2023.116629_bb0330","author":"U.S. Environmental Protection Agency"},{"key":"10.1016\/j.taap.2023.116629_bb0335","author":"U.S. Environmental Protection Agency"},{"key":"10.1016\/j.taap.2023.116629_bb0340","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1016\/j.febslet.2014.03.051","article-title":"Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice","volume":"588","author":"Usui","year":"2014","journal-title":"FEBS Lett."},{"key":"10.1016\/j.taap.2023.116629_bb0345","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1186\/1471-2148-11-351","article-title":"Sperm structure and motility in the eusocial naked mole-rat, Heterocephalus glaber: a case of degenerative orthogenesis in the absence of sperm competition?","volume":"11","author":"van der Horst","year":"2011","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.taap.2023.116629_bb0350","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1146\/annurev-pharmtox-010617-052429","article-title":"Mechanism of neonicotinoid toxicity: impact on oxidative stress and metabolism","volume":"58","author":"Wang","year":"2018","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.taap.2023.116629_bb0355","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1186\/s12917-022-03336-y","article-title":"Impact of bisphenol-A on the spliceosome and meiosis of sperm in the testis of adolescent mice","volume":"18","author":"Wang","year":"2022","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0360","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s11356-022-22270-y","article-title":"Meta-analysis of neonicotinoid insecticides in global surface waters","volume":"30","author":"Wang","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0365","doi-asserted-by":"crossref","first-page":"17285","DOI":"10.1007\/s11356-017-9240-x","article-title":"The environmental risks of neonicotinoid pesticides: a review of the evidence post 2013","volume":"24","author":"Wood","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0370","series-title":"Pharmacological Experimental Methodology","author":"Xu","year":"1982"},{"key":"10.1016\/j.taap.2023.116629_bb0375","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1292\/jvms.17-0154","article-title":"Prenatal and early postnatal NOAEL-dose clothianidin exposure leads to a reduction of germ cells in juvenile male mice","volume":"79","author":"Yanai","year":"2017","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.taap.2023.116629_bb0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114091","article-title":"The characteristics and potential risks of neonicotinoid residues in soils of different types of land use in Hangzhou","volume":"245","author":"Ying","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.taap.2023.116629_bb0385","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135163","article-title":"Imidacloprid disrupts the endocrine system by interacting with androgen receptor in male mice","volume":"708","author":"Yuan","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.taap.2023.116629_bb0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107186","article-title":"Urinary neonicotinoid concentrations and pubertal development in Chinese adolescents: a cross-sectional study","volume":"163","author":"Yue","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2023.116629_bb0395","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.jsxm.2017.09.001","article-title":"Formaldehyde inhibits sexual behavior and expression of steroidogenic enzymes in the testes of mice","volume":"14","author":"Zang","year":"2017","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.taap.2023.116629_bb0400","doi-asserted-by":"crossref","first-page":"47571","DOI":"10.1007\/s11356-022-19143-9","article-title":"Biochemical and histopathological investigation of the protective effects of melatonin and vitamin E against the damage caused by acetamiprid in Balb-c mouse testicles at light and electron microscopic level","volume":"29","author":"Zayman","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.taap.2023.116629_bb0405","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107201","article-title":"Human exposure to neonicotinoids and the associated health risks: a review","volume":"163","author":"Zhang","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2023.116629_bb0410","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1093\/toxsci\/kfx182","article-title":"1,2-Dichloroethane induces reproductive toxicity mediated by the CREM\/CREB signaling pathway in male NIH Swiss mice","volume":"160","author":"Zhang","year":"2017","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.taap.2023.116629_bb0415","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.envpol.2017.12.101","article-title":"Potential human exposures to neonicotinoid insecticides: a review","volume":"236","author":"Zhang","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.taap.2023.116629_bb0420","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105114","article-title":"A nationwide survey of urinary concentrations of neonicotinoid insecticides in China","volume":"132","author":"Zhang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.taap.2023.116629_bb0430","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/biolre\/ioy059","article-title":"Leydig cells: formation, function, and regulation","volume":"99","author":"Zirkin","year":"2018","journal-title":"Biol. Reprod."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X23002685?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X23002685?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T21:05:02Z","timestamp":1758575102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X23002685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":85,"alternative-id":["S0041008X23002685"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2023.116629","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reproductive effects of pubertal exposure to neonicotinoid thiacloprid in immature male mice","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2023.116629","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116629"}}