{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T12:14:29Z","timestamp":1793621669973,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002717","name":"Minist\u00e8re de l'Enseignement Sup\u00e9rieur et de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.taap.2024.117018","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T18:03:51Z","timestamp":1719597831000},"page":"117018","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Low-dose dimethylfumarate attenuates colitis-associated cancer in mice through M2 macrophage polarization and blocking oxidative stress"],"prefix":"10.1016","volume":"489","author":[{"given":"Ismahane","family":"Abdelaziz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelkader","family":"Bounaama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahia","family":"Djerdjouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zine-Charaf","family":"Amir-Tidadini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.taap.2024.117018_bb0005","doi-asserted-by":"crossref","first-page":"3144","DOI":"10.7150\/jca.37777","article-title":"Gastrointestinal toxic effects in patients with cancer receiving platinum-based therapy","volume":"11","author":"Abu-Sbeih","year":"2020","journal-title":"J. Cancer"},{"key":"10.1016\/j.taap.2024.117018_bb0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"Catalase in vitro","volume":"105","author":"Aebi","year":"1984","journal-title":"Methods Enzymol."},{"issue":"24","key":"10.1016\/j.taap.2024.117018_bb0015","doi-asserted-by":"crossref","first-page":"9517","DOI":"10.1073\/pnas.1119038109","article-title":"Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization","volume":"109","author":"Arranz","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.taap.2024.117018_bb0020","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00423-006-0073-1","article-title":"Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair","volume":"391","author":"Bartsch","year":"2006","journal-title":"Langenbecks Arch. Surg."},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0025","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1152\/physrev.00040.2012","article-title":"Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases","volume":"94","author":"Bhattacharyya","year":"2014","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.taap.2024.117018_bb0030","doi-asserted-by":"crossref","first-page":"3057268","DOI":"10.1155\/2017\/3057268","article-title":"EGCG maintains Th1\/Th2 balance and mitigates ulcerative colitis induced by dextran sulfate sodium through TLR4\/MyD88\/NF-\u03baB signaling pathway in rats","volume":"2017","author":"Bing","year":"2017","journal-title":"Can. J. Gastroenterol. Hepatol."},{"issue":"2\u20133","key":"10.1016\/j.taap.2024.117018_bb0035","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.tox.2012.08.014","article-title":"Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-\u03b21 and HES-1 transcripts in 1,2-dimethylhydrazine-colon carcinogenesis in mice","volume":"302","author":"Bounaama","year":"2012","journal-title":"Toxicology"},{"key":"10.1016\/j.taap.2024.117018_bb0040","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"issue":"18","key":"10.1016\/j.taap.2024.117018_bb0045","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1089\/ars.2015.6622","article-title":"Pharmacodynamics of dimethyl fumarate are tissue specific and involve NRF2-dependent and -independent mechanisms","volume":"24","author":"Brennan","year":"2016","journal-title":"Antioxid. Redox Signal."},{"issue":"4","key":"10.1016\/j.taap.2024.117018_bb0050","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1093\/ecco-jcc\/jjv231","article-title":"Dimethyl fumarate reduces inflammatory responses in experimental colitis","volume":"10","author":"Casili","year":"2016","journal-title":"J. Crohns Colitis"},{"issue":"7","key":"10.1016\/j.taap.2024.117018_bb0055","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/apt.12651","article-title":"Systematic review with meta-analysis: the declining risk of colorectal cancer in ulcerative colitis","volume":"39","author":"Casta\u00f1o-Milla","year":"2014","journal-title":"Aliment. Pharmacol. Ther."},{"issue":"4","key":"10.1016\/j.taap.2024.117018_bib302","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/carcin\/21.4.757","article-title":"Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. Relevance to colitis-associated neoplasia in the human: a study of histopathology, B-catenin and p53 expression and the role of inflammation","volume":"21","author":"Cooper","year":"2000","journal-title":"Carcinogenesis"},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0060","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1006\/bbrc.1995.1094","article-title":"Arginase induction by suppressors of nitric oxide synthesis (IL-4, IL-10 and PGE2) in murine bone-marrow-derived macrophages","volume":"206","author":"Corraliza","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"01","key":"10.1016\/j.taap.2024.117018_bb0065","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1038\/mi.2008.40","article-title":"The role of IL-13 and NK T cells in experimental and human ulcerative colitis","volume":"1","author":"Fuss","year":"2008","journal-title":"Mucosal Immunol."},{"issue":"3","key":"10.1016\/j.taap.2024.117018_bb0070","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.4049\/jimmunol.157.3.1261","article-title":"Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn\u2019s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5","volume":"157","author":"Fuss","year":"1996","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0075","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3934\/genet.2017.2.103","article-title":"DNA damage by lipid peroxidation products: implications in cancer, inflammation and autoimmunity","volume":"4","author":"Gentile","year":"2017","journal-title":"AIMS Genet."},{"issue":"6003","key":"10.1016\/j.taap.2024.117018_bb0080","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1126\/science.1192912","article-title":"ATM activation by oxidative stress","volume":"330","author":"Guo","year":"2010","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0085","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s12974-016-0559-x","article-title":"Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2\/hemoxygenase-1 pathway by altering the balance of M1\/M2 macrophages","volume":"13","author":"Han","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.taap.2024.117018_bb0090","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.612826","article-title":"Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment","volume":"12","author":"Hanus","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.taap.2024.117018_bb0100","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/351204","article-title":"Association of levels of antibodies from patients with inflammatory bowel disease with extracellular proteins of food and probiotic bacteria","volume":"2014","author":"Hevia","year":"2014","journal-title":"Biomed. Res. Int."},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0105","doi-asserted-by":"crossref","first-page":"6078","DOI":"10.1038\/s41598-020-63143-z","article-title":"PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio","volume":"10","author":"Horuluoglu","year":"2020","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.taap.2024.117018_bb0110","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1007\/s00384-017-2907-4","article-title":"Preoperative alkaline phosphatase elevation was associated with poor survival in colorectal cancer patients","volume":"32","author":"Hung","year":"2017","journal-title":"Int. J. Colorectal Dis."},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0115","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1038\/s41467-020-15549-6","article-title":"Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer","volume":"11","author":"Irrazabal","year":"2020","journal-title":"Nat. Commun."},{"issue":"1\u20132","key":"10.1016\/j.taap.2024.117018_bb0120","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0027-5107(01)00091-4","article-title":"The contribution of endogenous sources of DNA damage to the multiple mutations in cancer","volume":"477","author":"Jackson","year":"2001","journal-title":"Mutat. Res."},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0125","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s12957-018-1428-0","article-title":"Genomic characterization of colitis-associated colorectal cancer","volume":"16","author":"Kameyama","year":"2018","journal-title":"World J. Surg. Oncol."},{"key":"10.1016\/j.taap.2024.117018_bb0130","doi-asserted-by":"crossref","first-page":"3334994","DOI":"10.1155\/2021\/3334994","article-title":"Curcumin alleviated dextran sulfate sodium-induced colitis by regulating M1\/M2 macrophage polarization and TLRs signaling pathway","volume":"2021","author":"Kang","year":"2021","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"7","key":"10.1016\/j.taap.2024.117018_bb0135","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1074\/jbc.M115.679704","article-title":"Dimethyl fumarate inhibits the nuclear factor \u03baB pathway in breast cancer cells by covalent modification of p65 protein","volume":"291","author":"Kastrati","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.taap.2024.117018_bb0140","doi-asserted-by":"crossref","first-page":"6058147","DOI":"10.1155\/2016\/6058147","article-title":"Tumor-associated macrophages and neutrophils in tumor microenvironment","volume":"2016","author":"Kim","year":"2016","journal-title":"Mediators Inflamm."},{"issue":"6387","key":"10.1016\/j.taap.2024.117018_bb0145","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1126\/science.aan4665","article-title":"Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity","volume":"360","author":"Kornberg","year":"2018","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.taap.2024.117018_bb0150","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/0016-5085(84)90202-6","article-title":"Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models","volume":"87","author":"Krawisz","year":"1984","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.taap.2024.117018_bb0155","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1002\/ibd.20383","article-title":"Enhanced formation of advanced oxidation protein products in IBD","volume":"14","author":"Krzystek-Korpacka","year":"2008","journal-title":"Inflamm. Bowel Dis."},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0160","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1158\/2326-6066.CIR-19-0514","article-title":"Cross-talk between colon cells and macrophages increases ST6GALNAC1 and MUC1-sTn expression in ulcerative colitis and colitis-associated colon cancer","volume":"8","author":"Kvorjak","year":"2020","journal-title":"Cancer Immunol. Res."},{"issue":"12","key":"10.1016\/j.taap.2024.117018_bb0165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0003952","article-title":"Mucin dynamics in intestinal bacterial infection","volume":"3","author":"Lind\u00e9n","year":"2008","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0170","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12974-020-01751-2","article-title":"Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-\u03baB signaling pathway and pyroptosis after secondary spinal cord injury","volume":"17","author":"Liu","year":"2020","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0175","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/s12876-021-01740-6","article-title":"Distinct clinical phenotypes for Crohn's disease derived from patient surveys","volume":"21","author":"Liu","year":"2021","journal-title":"BMC Gastroenterol."},{"issue":"6","key":"10.1016\/j.taap.2024.117018_bb0180","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/s41419-021-03778-6","article-title":"DA-DRD5 signaling controls colitis by regulating colonic M1\/M2 macrophage polarization","volume":"12","author":"Liu","year":"2021","journal-title":"Cell Death Dis."},{"issue":"4","key":"10.1016\/j.taap.2024.117018_bb0185","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1302\/2046-3758.104.BJR-2020-0085.R2","article-title":"Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-\u03baB pathway","volume":"10","author":"Lou","year":"2021","journal-title":"Bone Joint Res."},{"issue":"8","key":"10.1016\/j.taap.2024.117018_bb0190","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1158\/0008-5472.CAN-13-1070","article-title":"p53 and NF-\u03baB coregulate proinflammatory gene responses in human macrophages","volume":"74","author":"Lowe","year":"2014","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0195","first-page":"59","article-title":"5-Fluorouracil-induced colitis\u2014a review based upon consideration of 6 cases","volume":"40","author":"Madisch","year":"2002","journal-title":"Z. Gastroenterol."},{"issue":"3","key":"10.1016\/j.taap.2024.117018_bb0200","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","article-title":"Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase","volume":"47","author":"Marklund","year":"1974","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.taap.2024.117018_bb0205","doi-asserted-by":"crossref","first-page":"6501046","DOI":"10.1155\/2017\/6501046","article-title":"Measurement and clinical significance of biomarkers of oxidative stress in humans","volume":"2017","author":"Marrocco","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0210","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1006\/niox.2000.0319","article-title":"A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite","volume":"5","author":"Miranda","year":"2001","journal-title":"Nitric Oxide"},{"issue":"5","key":"10.1016\/j.taap.2024.117018_bb0215","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/CAD.0000000000000338","article-title":"Efficacy and safety analysis of chemotherapy for advanced colitis-associated colorectal cancer in Japan","volume":"27","author":"Nio","year":"2016","journal-title":"Anticancer Drugs"},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0220","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"issue":"2","key":"10.1016\/j.taap.2024.117018_bb0225","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1538\/expanim.63.133","article-title":"Overexpression of GATA-3 in T cells accelerates dextran sulfate sodium-induced colitis","volume":"63","author":"Okamura","year":"2014","journal-title":"Exp. Anim."},{"issue":"3","key":"10.1016\/j.taap.2024.117018_bb0230","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1074\/mcp.RA118.000922","article-title":"Identification of novel protein targets of dimethyl fumarate modification in neurons and astrocytes reveals actions independent of Nrf2 stabilization","volume":"18","author":"Piroli","year":"2019","journal-title":"Mol. Cell. Proteomics"},{"issue":"55","key":"10.1016\/j.taap.2024.117018_bb0235","doi-asserted-by":"crossref","first-page":"94650","DOI":"10.18632\/oncotarget.21841","article-title":"Matrix metalloproteinase MMP9 maintains epithelial barrier function and preserves mucosal lining in colitis associated cancer","volume":"8","author":"Pujada","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.taap.2024.117018_bb0240","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3389\/fimmu.2014.00532","article-title":"Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages","volume":"5","author":"Rath","year":"2014","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.taap.2024.117018_bib301","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.4049\/jimmunol.1101712","article-title":"Th2 skewing by activation of Nrf2 in CD4(+) T cells","volume":"188","author":"Rockwell","year":"2012","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.taap.2024.117018_bb0245","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1158\/1535-7163.MCT-16-0405","article-title":"Dimethyl fumarate controls the NRF2\/DJ-1 Axis in Cancer cells: therapeutic applications","volume":"16","author":"Saidu","year":"2017","journal-title":"Mol. Cancer Ther."},{"issue":"3","key":"10.1016\/j.taap.2024.117018_bb0250","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1053\/j.gastro.2021.10.035","article-title":"Colorectal Cancer in inflammatory bowel disease: mechanisms and management","volume":"162","author":"Shah","year":"2022","journal-title":"Gastroenterology"},{"issue":"11","key":"10.1016\/j.taap.2024.117018_bb0255","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1349-7006.2003.tb01386.x","article-title":"A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate","volume":"94","author":"Tanaka","year":"2003","journal-title":"Cancer Sci."},{"issue":"7","key":"10.1016\/j.taap.2024.117018_bb0260","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1200\/JCO.1996.14.7.2043","article-title":"Influence of inflammatory bowel disease on the ability of patients to tolerate systemic fluorouracil-based chemotherapy","volume":"14","author":"Tiersten","year":"1996","journal-title":"J. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.taap.2024.117018_bb0265","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jcmgh.2014.11.006","article-title":"Mechanisms of immune signaling in colitis-associated Cancer","volume":"1","author":"Waldner","year":"2015","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.taap.2024.117018_bb0270","doi-asserted-by":"crossref","first-page":"9875298","DOI":"10.1155\/2016\/9875298","article-title":"Oxidative stress and carbonyl lesions in ulcerative colitis and associated colorectal cancer","volume":"2016","author":"Wang","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"3","key":"10.1016\/j.taap.2024.117018_bb0275","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1189\/jlb.0311124","article-title":"SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis","volume":"90","author":"Weisser","year":"2011","journal-title":"J. Leukoc. Biol."},{"issue":"5","key":"10.1016\/j.taap.2024.117018_bb0280","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1038\/ki.1996.186","article-title":"Advanced oxidation protein products as a novel marker of oxidative stress in uremia","volume":"49","author":"Witko-Sarsat","year":"1996","journal-title":"Kidney Int."},{"issue":"38","key":"10.1016\/j.taap.2024.117018_bb0285","doi-asserted-by":"crossref","first-page":"20030","DOI":"10.1074\/jbc.M116.731216","article-title":"NADPH oxidases are essential for macrophage differentiation","volume":"291","author":"Xu","year":"2016","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.taap.2024.117018_bb0290","doi-asserted-by":"crossref","first-page":"e151","DOI":"10.1016\/j.clcc.2020.02.008","article-title":"Systemic chemotherapy for metastatic colitis-associated cancer has a worse outcome than sporadic colorectal cancer: matched case cohort analysis","volume":"19","author":"Yaeger","year":"2020","journal-title":"Clin. Colorectal Cancer"},{"issue":"5","key":"10.1016\/j.taap.2024.117018_bb0295","first-page":"1874","article-title":"Sequential analysis of morphological and biological properties of beta-catenin- accumulated crypts, provable premalignant lesions independent of aberrant crypt foci in rat colon carcinogenesis","volume":"61","author":"Yamada","year":"2001","journal-title":"Cancer Res."},{"issue":"6","key":"10.1016\/j.taap.2024.117018_bb0300","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1093\/jee\/96.6.1855","article-title":"Characterization of general esterases from methyl parathion-resistant and -susceptible populations of western corn rootworm (Coleoptera: Chrysomelidae)","volume":"96","author":"Zhou","year":"2003","journal-title":"J. Econ. Entomol."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X24002163?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X24002163?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T20:58:48Z","timestamp":1720558728000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X24002163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":61,"alternative-id":["S0041008X24002163"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2024.117018","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-dose dimethylfumarate attenuates colitis-associated cancer in mice through M2 macrophage polarization and blocking oxidative stress","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2024.117018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117018"}}