{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:41:59Z","timestamp":1777074119940,"version":"3.51.4"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.taap.2024.117041","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T19:04:43Z","timestamp":1721847883000},"page":"117041","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Alpha-Asarone attenuates alcohol-induced hepatotoxicity in a murine model by ameliorating oxidative stress, inflammation, and modulating apoptotic-Autophagic cell death"],"prefix":"10.1016","volume":"490","author":[{"given":"Nada A.M.","family":"Ali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir Mohamed","family":"Abdelhamid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norhan M.","family":"El-Sayed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmaa","family":"Radwan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.taap.2024.117041_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.117908","article-title":"Empagliflozin ameliorates ethanol-induced liver injury by modulating NF-\u03baB\/Nrf-2\/PPAR-\u03b3 interplay in mice","volume":"256","author":"Abdelhamid","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.taap.2024.117041_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107963","article-title":"Telmisartan alleviates alcohol-induced liver injury by activation of PPAR-\u03b3\/ Nrf-2 crosstalk in mice","volume":"99","author":"Abdelhamid","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.taap.2024.117041_bb0015","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1146\/annurev.arplant.55.031903.141701","article-title":"Reactive oxygen species: metabolism, oxidative stress, and signal transduction","volume":"55","author":"Apel","year":"2004","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.taap.2024.117041_bb0085","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3923\/ajb.2014.107.113","article-title":"Antioxidant properties of alpha asarone","volume":"9","author":"Asha Devi","year":"2014","journal-title":"Asian J. Biochem."},{"key":"10.1016\/j.taap.2024.117041_bb0030","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/nprot.2013.032","article-title":"Mouse model of chronic and binge ethanol feeding (the NIAAA model)","volume":"8","author":"Bertola","year":"2013","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.taap.2024.117041_bb0035","doi-asserted-by":"crossref","first-page":"166s","DOI":"10.1097\/01.alc.0000189280.19073.28","article-title":"Activation of the innate immune system and alcoholic liver disease: effects of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol?","volume":"29","author":"Bode","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.taap.2024.117041_bb0040","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.taap.2024.117041_bb0045","doi-asserted-by":"crossref","first-page":"17756","DOI":"10.3748\/wjg.v20.i47.17756","article-title":"Pathogenesis of alcoholic liver disease: role of oxidative metabolism","volume":"20","author":"Ceni","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.taap.2024.117041_bb0050","first-page":"20658","article-title":"\u03b2-Asarone prevents A\u03b225-35-induced inflammatory responses and autophagy in SH-SY5Y cells: down expression Beclin-1, LC3B and up expression Bcl-2","volume":"8","author":"Chang","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.taap.2024.117041_bb0055","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.phymed.2017.04.003","article-title":"Pharmacology and toxicology of \u03b1- and \u03b2-Asarone: a review of preclinical evidence","volume":"32","author":"Chellian","year":"2017","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"key":"10.1016\/j.taap.2024.117041_bb0060","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3858\/emm.2010.42.3.021","article-title":"Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium","volume":"42","author":"Chen","year":"2010","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.taap.2024.117041_bb0070","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s43094-021-00193-8","article-title":"Metformin and asarone inhibit HepG2 cell proliferation in a high glucose environment by regulating AMPK and Akt signaling pathway","volume":"7","author":"Das","year":"2021","journal-title":"Future Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.taap.2024.117041_bb0075","series-title":"Alcohol and its Biomarkers","first-page":"121","article-title":"Chapter 5 - liver enzymes as alcohol biomarkers","author":"Dasgupta","year":"2015"},{"key":"10.1016\/j.taap.2024.117041_bb0080","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jhep.2010.08.007","article-title":"Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease","volume":"54","author":"Derdak","year":"2011","journal-title":"J. Hepatol."},{"key":"10.1016\/j.taap.2024.117041_bb0090","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1515\/hsz-2012-0119","article-title":"Mitophagy: mechanisms, pathophysiological roles, and analysis","volume":"393","author":"Ding","year":"2012","journal-title":"Biol. Chem."},{"key":"10.1016\/j.taap.2024.117041_bb0095","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nrd.2017.22","article-title":"Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles","volume":"16","author":"Galluzzi","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.taap.2024.117041_bb0100","series-title":"Alcohol use and burden for 195 countries and territories, 1990\u20132016: a systematic analysis for the global burden of disease study 2016","first-page":"1015","volume":"392","author":"Griswold","year":"2018"},{"key":"10.1016\/j.taap.2024.117041_bb0105","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3748\/wjg.v22.i1.37","article-title":"Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes","volume":"22","author":"Han","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.taap.2024.117041_bb0110","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1111\/j.1525-1594.2010.01121.x","article-title":"The role of phospho-adenosine monophosphate-activated protein kinase and vascular endothelial growth factor in a model of chronic heart failure","volume":"34","author":"Heidrich","year":"2010","journal-title":"Artif. Organs"},{"key":"10.1016\/j.taap.2024.117041_bb0120","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1530-0277.2002.tb02434.x","article-title":"A role for interleukin-10 in alcohol-induced liver sensitization to bacterial lipopolysaccharide","volume":"26","author":"Hill","year":"2002","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.taap.2024.117041_bb0125","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0741-8329(02)00215-X","article-title":"Ethanol, oxidative stress, and cytokine-induced liver cell injury","volume":"27","author":"Hoek","year":"2002","journal-title":"Alcohol (Fayetteville, NY)"},{"key":"10.1016\/j.taap.2024.117041_bb0130","series-title":"The quantitative ER immunohistochemical analysis in breast cancer: Detecting the 3+ 0, 4+ 0, and 5+ 0 allred score cases","first-page":"461","volume":"55","author":"Ili\u0107","year":"2019"},{"issue":"2","key":"10.1016\/j.taap.2024.117041_bb0115","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/hep.22709","article-title":"Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia","volume":"49","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.taap.2024.117041_bb0135","first-page":"696","volume":"22","author":"Ishak","year":"1995","journal-title":"Histological grading and staging of chronic hepatitis."},{"key":"10.1016\/j.taap.2024.117041_bb0145","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.3748\/wjg.v24.i25.2661","article-title":"Apoptosis and non-alcoholic fatty liver diseases","volume":"24","author":"Kanda","year":"2018","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.taap.2024.117041_bb0150","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.jhep.2019.06.019","article-title":"The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice","volume":"71","author":"Kim","year":"2019","journal-title":"J. Hepatol."},{"key":"10.1016\/j.taap.2024.117041_bb0155","doi-asserted-by":"crossref","first-page":"445","DOI":"10.4161\/auto.19496","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy","volume":"8","author":"Klionsky","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2024.117041_bb0160","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1080\/03602532.2019.1679169","article-title":"Ethanol and its metabolites: update on toxicity, benefits, and focus on immunomodulatory effects","volume":"51","author":"Le Dar\u00e9","year":"2019","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.taap.2024.117041_bb0165","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/978-981-15-0602-4_4","article-title":"AMPK and autophagy","volume":"1206","author":"Li","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.taap.2024.117041_bb0170","first-page":"26087","volume":"16","author":"Li","year":"2015","journal-title":"The Role of Oxidative Stress and Antioxidants in Liver Diseases."},{"key":"10.1016\/j.taap.2024.117041_bb0175","series-title":"Protein immunoblotting","first-page":"273","author":"LILLEHOJ","year":"1994"},{"key":"10.1016\/j.taap.2024.117041_bb0180","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.jhep.2013.01.011","article-title":"Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice","volume":"58","author":"Lin","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.taap.2024.117041_bb0185","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1053\/j.gastro.2018.05.011","article-title":"Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual Data From Controlled Trials","volume":"155","author":"Louvet","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.taap.2024.117041_bb0190","doi-asserted-by":"crossref","first-page":"3622","DOI":"10.1080\/15548627.2021.1886829","article-title":"AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy","volume":"17","author":"Lu","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2024.117041_bb0195","series-title":"Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data","first-page":"255","volume":"60","author":"Mathurin","year":"2011"},{"key":"10.1016\/j.taap.2024.117041_bb0200","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1055\/s-2007-1007110","article-title":"Cytokines in alcoholic liver disease","volume":"19","author":"McClain","year":"1999","journal-title":"Semin. Liver Dis."},{"key":"10.1016\/j.taap.2024.117041_bb0205","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S0002-9343(00)00412-5","article-title":"The evolution of free radicals and oxidative stress","volume":"108","author":"McCord","year":"2000","journal-title":"Am. J. Med."},{"key":"10.1016\/j.taap.2024.117041_bb0210","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.cgh.2016.08.047","article-title":"Medical Management of Severe Alcoholic Hepatitis: expert review from the clinical practice updates committee of the AGA Institute","volume":"15","author":"Mitchell","year":"2017","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.taap.2024.117041_bb0215","doi-asserted-by":"crossref","first-page":"542","DOI":"10.4161\/auto.4600","article-title":"How to interpret LC3 immunoblotting","volume":"3","author":"Mizushima","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.taap.2024.117041_bb0220","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cell.2010.01.028","article-title":"Methods in mammalian autophagy research","volume":"140","author":"Mizushima","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.taap.2024.117041_bb0225","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.yexmp.2013.10.006","article-title":"Changes in the pathogenesis of alcohol-induced liver disease \u2014 preclinical studies","volume":"95","author":"Neuman","year":"2013","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.taap.2024.117041_bb0230","doi-asserted-by":"crossref","DOI":"10.3390\/nu12072006","article-title":"Asaronic acid inhibited glucose-triggered M2-phenotype shift through disrupting the formation of coordinated signaling of IL-4R\u03b1-Tyk2-STAT6 and GLUT1-Akt-mTOR-AMPK","volume":"12","author":"Oh","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.taap.2024.117041_bb0235","first-page":"460","article-title":"An overview of autophagy: morphology, mechanism","volume":"20","author":"Parzych","year":"2014","journal-title":"Regulation"},{"key":"10.1016\/j.taap.2024.117041_bb0240","first-page":"599","article-title":"Apoptotic markers p53, Bcl-2 and Bax in primary lung cancer","volume":"20","author":"Porebska","year":"2006","journal-title":"In vivo (Athens, Greece)"},{"key":"10.1016\/j.taap.2024.117041_bb0245","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.jhep.2010.07.006","article-title":"Autophagy in liver diseases","volume":"53","author":"Rautou","year":"2010","journal-title":"J. Hepatol."},{"key":"10.1016\/j.taap.2024.117041_bb0255","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.pneurobio.2013.06.002","article-title":"Impaired autophagy and APP processing in Alzheimer's disease: the potential role of Beclin 1 interactome","volume":"106-107","author":"Salminen","year":"2013","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.taap.2024.117041_bb0260","first-page":"591","article-title":"Protective effect of \u03b1-asarone and \u03b2-asarone on A\u03b2 -induced inflammatory response in PC12 cells and its. Zhejiang da xue xue bao. Yi xue ban = journal of Zhejiang University","volume":"50","author":"Shi","year":"2021","journal-title":"Medical sciences"},{"key":"10.1016\/j.taap.2024.117041_bb0265","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4062\/biomolther.2013.102","article-title":"\u03b1-Asarone ameliorates memory deficit in lipopolysaccharide-treated mice via suppression of pro-inflammatory cytokines and microglial activation","volume":"22","author":"Shin","year":"2014","journal-title":"Biomol. Ther."},{"key":"10.1016\/j.taap.2024.117041_bb0270","doi-asserted-by":"crossref","first-page":"173","DOI":"10.5009\/gnl16477","article-title":"Pathophysiology and Management of Alcoholic Liver Disease: update 2016","volume":"11","author":"Stickel","year":"2017","journal-title":"Gut and liver"},{"key":"10.1016\/j.taap.2024.117041_bb0275","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.biopha.2017.12.051","article-title":"\u03b1-Asarone reduce proteinuria by restoring antioxidant enzymes activities and regulating necrosis factor \u03baB signaling pathway in doxorubicin-induced nephrotic syndrome","volume":"98","author":"Sutariya","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.taap.2024.117041_bb0280","series-title":"LC3 and Autophagy. Methods in Molecular Biology (Clifton, N.J.)","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/978-1-59745-157-4_4","volume":"vol. 445","author":"Tanida","year":"2008"},{"issue":"13","key":"10.1016\/j.taap.2024.117041_bb0285","doi-asserted-by":"crossref","first-page":"103","DOI":"10.22270\/jddt.v12i3.5335","article-title":"\u0391-Asarone protects CCL4 induced hepatotoxicity in experimental rats by inhibiting oxidative stress and cytokines","volume":"12","author":"Tathe","year":"2022","journal-title":"Journal of Drug Delivery and Therapeutics"},{"key":"10.1016\/j.taap.2024.117041_bb0290","doi-asserted-by":"crossref","first-page":"5515","DOI":"10.1080\/07391102.2023.2227712","article-title":"Isolation, identification, and characterization of \u03b1- asarone, from hydromethanolic leaf extract of Acorus calamus L. and its apoptosis-inducing mechanism in A549 cells","volume":"42","author":"Thakkar","year":"2024","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.taap.2024.117041_bb0295","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/cld.172","article-title":"Histopathology of alcoholic liver disease","volume":"2","author":"Theise","year":"2013","journal-title":"Clinical liver disease"},{"key":"10.1016\/j.taap.2024.117041_bb0300","series-title":"Fundamentals of Clinical Chemistry","author":"Tietz","year":"1976"},{"key":"10.1016\/j.taap.2024.117041_bb0305","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/nrgastro.2016.185","article-title":"Autophagy in the liver: functions in health and disease","volume":"14","author":"Ueno","year":"2017","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.taap.2024.117041_bb0310","series-title":"A mechanistic review of cell death in alcohol-induced liver injury","first-page":"1215","volume":"40","author":"Wang","year":"2016"},{"key":"10.1016\/j.taap.2024.117041_bb0315","series-title":"Role of autophagy in alcohol and drug-induced liver injury","first-page":"111075","volume":"136","author":"Williams","year":"2020"},{"key":"10.1016\/j.taap.2024.117041_bb0320","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2174\/1566524033479555","article-title":"Death receptor activation-induced hepatocyte apoptosis and liver injury","volume":"3","author":"Yin","year":"2003","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.taap.2024.117041_bb0325","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.neuroscience.2021.08.006","article-title":"Neuroprotective effect of alpha-asarone on the rats model of cerebral ischemia-reperfusion stroke via ameliorating glial activation and autophagy","volume":"473","author":"Zhang","year":"2021","journal-title":"Neuroscience"},{"key":"10.1016\/j.taap.2024.117041_bb0330","series-title":"Neuroprotective effect of alpha-asarone on the rats model of cerebral ischemia\u2013reperfusion stroke via ameliorating glial activation and autophagy","first-page":"130","volume":"473","author":"Zhang","year":"2021"},{"key":"10.1016\/j.taap.2024.117041_bb0335","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1002\/jcp.25934","article-title":"Acute ethanol exposure-induced autophagy-mediated cardiac injury via activation of the ROS-JNK-Bcl-2 pathway","volume":"233","author":"Zhu","year":"2018","journal-title":"J. Cell. Physiol."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X24002394?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X24002394?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T23:26:06Z","timestamp":1723332366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X24002394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":62,"alternative-id":["S0041008X24002394"],"URL":"https:\/\/doi.org\/10.1016\/j.taap.2024.117041","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alpha-Asarone attenuates alcohol-induced hepatotoxicity in a murine model by ameliorating oxidative stress, inflammation, and modulating apoptotic-Autophagic cell death","name":"articletitle","label":"Article Title"},{"value":"Toxicology and Applied Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.taap.2024.117041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117041"}}